Physicochemical properties of articular cartilage

Maroudas, A.

Year	Entry
1994	Mow VC, Bachrach NM, Setton LA, Guilak F. Stress, strain, pressure and flow fields in articular cartilage and chondrocytes. In: Mow VC, Tran-Son-Tay R, Guilak F, Hochmuth RM, eds. Cell Mechanics and Cellular Engineering. Symposium on Cell Mechanics and Cellular Engineering; July 10-15, 1994. New York, NY: Springer-Verlag; 1994:345-379.
1994	Guilak F, Donahue HJ, Zell RA, Grande D, McLeod KJ, Rubin CT. Deformation-induced calcium signaling in articular chondrocytes. In: Mow VC, Tran-Son-Tay R, Guilak F, Hochmuth RM, eds. Cell Mechanics and Cellular Engineering. Symposium on Cell Mechanics and Cellular Engineering; July 10-15, 1994. New York, NY: Springer-Verlag; 1994:380-397.
1994	Urban JPG, Hall AC. The effects of hydrostatic and osmotic pressures on chondrocyte metabolism. In: Mow VC, Tran-Son-Tay R, Guilak F, Hochmuth RM, eds. Cell Mechanics and Cellular Engineering. Symposium on Cell Mechanics and Cellular Engineering; July 10-15, 1994. New York, NY: Springer-Verlag; 1994:398-419.
2003	Ateshian GA, Hung CT. Functional properties of native articular cartilage. In: Guilak F, Butler DL, Goldstein SA, Mooney DJ, eds. Functional Tissue Engineering. New York, NY: Inc., Springer-Verlag; 2003:46-68.
2003	Hu JCY, Athanasiou KA. The role of mechanical forces in tissue engineering of articular cartilage. In: Guilak F, Butler DL, Goldstein SA, Mooney DJ, eds. Functional Tissue Engineering. New York, NY: Inc., Springer-Verlag; 2003:227-242.
2003	Guilak F, Setton LA. Functional tissue engineering and the role of biomechanical signaling in articular cartilage repair. In: Guilak F, Butler DL, Goldstein SA, Mooney DJ, eds. Functional Tissue Engineering. New York, NY: Inc., Springer-Verlag; 2003:277-290.
1997	Ishihara H, Warensjo K, Roberts S, Urban JPG. Proteoglycan synthesis in the intervertebral disk nucleus: the role of extracellular osmolality. Am J Physiol Cell Physiol. May 1997;272(5):C1499-C1506.
1996	Schinagl RM, Ting MK, Price JH, Sah RL. Video microscopy to quantitate the inhomogeneous equilibrium strain within articular cartilage during confined compression. Ann Biomed Eng. July–August 1996;24(4):500-512.
2003	Leddy HA, Guilak F. Site-specific molecular diffusion in articular cartilage measured using fluorescence recovery after photobleaching. Ann Biomed Eng. July–August 2003;31(7):753-760.
2004	Almarza AJ, Athanasiou KA. Design characteristics for the tissue engineering of cartilaginous tissues. Ann Biomed Eng. January 2004;32(1):2-17.
2006	Guilak F, Alexopoulos LG, Upton ML, Youn I, Choi JB, Cao L, Setton LA, Haider MA. The pericellular matrix as a transducer of biomechanical and biochemical signals in articular cartilage. Annals NY Acad Sci. April 2006;1068(1):498-512.
1990	O'Hara BP, Urban JP, Maroudas A. Influence of cyclic loading on the nutrition of articular cartilage. Ann Rheum Dis. July 1990;49(7):536-539.
2000	Grodzinsky AJ, Levenston ME, Jin M, Frank EH. Cartilage tissue remodeling in response to mechanical forces. Annu Rev Biomed Eng. 2000;2:691-713.
2002	Mow VC, Guo XE. Mechano-electrochemical properties of articular cartilage: their inhomogeneities and anisotropies. Annu Rev Biomed Eng. 2002;4:175-209.
1991	Sah RL-Y, Doong J-YH, Grodzinsky AJ, Plaas AHK, Sandy JD. Effects of compression on the loss of newly synthesized proteoglycans and proteins from cartilage explants. Arch Biochem Biophys. April 1991;286(1):209-29.
1994	Sah RL, Chen AC, Grodzinsky AJ, Trippel SB. Differential effects of bFGF and IGF-I on matrix metabolism in calf and adult bovine cartilage explants. Arch Biochem Biophys. January 1994;308(1):137-147.
2000	Bonassar LJ, Grodzinsky AJ, Srinivasan A, Davila SG, Trippel SB. Mechanical and physicochemical regulation of the action of insulin-like growth factor-I on articular cartilage. Arch Biochem Biophys. July 1, 2000;379(1):57-63.
2002	Eyre D. Articular cartilage and changes in arthritis: collagen of articular cartilage. Arthritis Res. 2002;4(1):30-35.
2007	Asanbaeva A, Masuda K, Thonar EJ-MA, Klisch SM, Sah RL. Mechanisms of cartilage growth: modulation of balance between proteoglycan and collagen in vitro using chondroitinase ABC. Arthritis Rheum. January 2007;56(1):188-198.
1989	Gray ML, Pizzanelli AM, Lee RC, Grodzinsky AJ, Swann DA. Kinetics of the chondrocyte biosynthetic response to compressive load and release. Biochim Biophys Acta. June 27, 1989;991(3):415-425.
1989	Urban JPG, Bayliss MT. Regulation of proteoglycan synthesis rate in cartilage in vitro: influence of extracellular ionic composition. Biochim Biophys Acta. July 21, 1989;992(1):59-65.
2002	Guilak F, Erickson GR, Ting-Beall HP. The effects of osmotic stress on the viscoelastic and physical properties of articular chondrocytes. Biophys J. February 2002;82(2):720-727.
1979	Urban JPG, Maroudas A, Bayliss MT, Dillon J. Swelling pressures of proteoglycans at the concentrations found in cartilaginous tissues. Biorheology. 1979;16(6):447-464.
1986	Mizrahi J, Maroudas A, Lanir Y, Ziv I, Webber TJ. The “instantaneous” deformation of cartilage: effects of collagen fiber orientation and osmotic stress. Biorheology. 1986;23(4):311-330.
2002	Wang CC-B, Guo XE, Sun D, Mow VC, Ateshian GA, Hung CT. The functional environment of chondrocytes within cartilage subjected to compressive loading: a theoretical and experimental approach. Biorheology. 2002;39(1-2):11-25.
1994	Urban JPG. The chondrocyte: a cell under pressure. Br J Rheumatol. October 1994;33(10):901-908.
1982	Jones IL, Klämfeldt A, Sandström T. The effect of continuous mechanical pressure upon the turnover of articular cartilage proteoglycans in vitro. Clin Orthop Relat Res. May 1982;165:283-289.
1990	Fithian DC, Kelly MA, Mow VC. Material properties and structure-function relationships in the menisci. Clin Orthop Relat Res. March 1990;252:19-31.
1999	Mow VC, Wang CC-B. Some bioengineering considerations for tissue engineering of articular cartilage. Clin Orthop Relat Res. October 1999;367(suppl):S204-S223.
1989	Heinegård D, Oldberg Å. Structure and biology of cartilage and bone matrix noncollagenous macromolecules. FASEB J. July 1989;3(9):2042-2051.
1975	Maroudas A, Stockwell RA, Nachemson A, Urban J. Factors involved in the nutrition of the human lumbar intervertebral disc: cellularity and diffusion of glucose in vitro. J Anat. September 1975;120(1):113-130.
1984	Mow VC, Holmes MH, Lai WM. Fluid transport and mechanical properties of articular cartilage: a review. J Biomech. 1984;17(5):377-394.
1987	Torzilli PA, Adams TC, Mis RJ. Transient solute diffusion in articular cartilage. J Biomech. 1987;20(2):203-214.
1987	Frank EH, Grodzinsky AJ. Cartilage electromechanics, I: electrokinetic transduction and the effects of electrolyte pH and ionic strength. J Biomech. 1987;20(6):615-627.
1987	Frank EH, Grodzinsky AJ. Cartilage electromechanics, II: a continuum model of cartilage electrokinetics and correlation with experiments. J Biomech. 1987;20(6):629-639.
1987	Mak AF, Lai WM, Mow VC. Biphasic indentation of articular cartilage, I: theoretical analysis. J Biomech. 1987;20(7):703-714.
1990	Kwan MK, Lai WM, Mow VC. A finite deformation theory for cartilage and other soft hydrated connective tissues, I: equilibrium results. J Biomech. 1990;23(2):145-155.
1990	Holmes MH, Mow VC. The nonlinear characteristics of soft gels and hydrated connective tissues in ultrafiltration. J Biomech. 1990;23(11):1145-1156.
1992	Hou JS, Mow VC, Lai WM, Holmes MH. An analysis of the squeeze-film lubrication mechanism for articular cartilage. J Biomech. March 1992;25(3):247-259.
1993	Setton LA, Zhu W, Mow VC. The biphasic poroviscoelastic behavior of articular cartilage: role of the surface zone in governing the compressive behavior. J Biomech. April–May 1993;26(4-5):581-592.
1993	Gu WY, Lai WM, Mow VC. Transport of fluid and ions through a porous-permeable charged-hydrated tissue, and streaming potential data on normal bovine articular cartilage. J Biomech. June 1993;26(6):709-723.
1995	Guilak F. Compression-induced changes in the shape and volume of the chondrocyte nucleus. J Biomech. December 1995;28(12):1529-1541.
1997	Khalsa PS, Eisenberg SR. Compressive behavior of articular cartilage is not completely explained by proteoglycan osmotic pressure. J Biomech. June 1997;30(6):589-594.
1998	Bachrach NM, Mow VC, Guilak F. Incompressibility of the solid matrix of articular cartilage under high hydrostatic pressures. J Biomech. May 1998;31(5):445-451.
1998	Soltz MA, Ateshian GA. Experimental verification and theoretical prediction of cartilage interstitial fluid pressurization at an impermeable contact interface in confined compression. J Biomech. October 1998;31(10):927-934.
1999	Jones WR, Ping Ting-Beall H, Lee GM, Kelley SS, Hochmuth RM, Guilak F. Alterations in the young’s modulus and volumetric properties of chondrocytes isolated from normal and osteoarthritic human cartilage. J Biomech. February 1999;32(2):119-127.
1999	Narmoneva DA, Wang JY, Setton LA. Nonuniform swelling-induced residual strains in articular cartilage. J Biomech. April 1999;32(4):401-408.
2000	Li LP, Buschmann MD, Shirazi-Adl A. A fibril reinforced nonhomogeneous poroelastic model for articular cartilage: inhomogeneous response in unconfined compression. J Biomech. December 2000;33(12):1533-1541.
2000	Guilak F, Mow VC. The mechanical environment of the chondrocyte: a biphasic finite element model of cell–matrix interactions in articular cartilage. J Biomech. December 2000;33(12):1663-1673.
2001	Chen AC, Bae WC, Schinagl RM, Sah RL. Depth- and strain-dependent mechanical and electromechanical properties of full-thickness bovine articular cartilage in confined compression. J Biomech. January 2001;34(1):1-12.
2001	Erickson GR, Alexopoulos LG, Guilak F. Hyper-osmotic stress induces volume change and calcium transients in chondrocytes by transmembrane, phospholipid, and G-protein pathways. J Biomech. December 2001;34(12):1527-1535.
2003	Park S, Krishnan R, Nicoll SB, Ateshian GA. Cartilage interstitial fluid load support in unconfined compression. J Biomech. December 2003;36(12):1785-1796.
2004	Ateshian GA, Chahine NO, Basalo IM, Hung CT. The correspondence between equilibrium biphasic and triphasic material properties in mixture models of articular cartilage. J Biomech. March 2004;37(3):391-400.
2004	Chahine NO, Wang CC-B, Hung CT, Ateshian GA. Anisotropic strain-dependent material properties of bovine articular cartilage in the transitional range from tension to compression. J Biomech. August 2004;37(8):1251-1261.
2007	Klein TJ, Chaudhry M, Bae WC, Sah RL. Depth-dependent biomechanical and biochemical properties of fetal, newborn, and tissue-engineered articular cartilage. J Biomech. January 2007;40(1):182-190.
2009	Ateshian GA. The role of interstitial fluid pressurization in articular cartilage lubrication. J Biomech. June 19, 2009;42(9):1163-1176.
2015	Oungoulian SR, Durney KM, Jones BK, Ahmad CS, Hung CT, Ateshian GA. Wear and damage of articular cartilage with friction against orthopedic implant materials. J Biomech. July 16, 2015;48(10):1957-1964.
2024	Rich MJ, Burnash S, Krishnan RR, Chubinskaya S, Loeser RF, Polacheck WJ, Diekman BO. Use of a novel magnetically actuated compression system to study the temporal dynamics of axial and lateral strain in human osteochondral plugs. J Biomech. January 2024;162:111887.
1981	Grodzinsky AJ, Roth V, Myers E, Grossman WD, Mow VC. The significance of electromechanical and osmotic forces in the nonequilibrium swelling behavior of articular cartilage in tension. J Biomech Eng. November 1981;103(4):221-231.
1984	Myers ER, Lai WM, Mow VC. A continuum theory and an experiment for the ion-induced swelling behavior of articular cartilage. J Biomech Eng. May 1984;106(2):151-158.
1987	Eisenberg SR, Grodzinsky AJ. The kinetics of chemically induced nonequilibrium swelling of articular cartilage and corneal stroma. J Biomech Eng. February 1987;109(1):79-89.
1989	Hou JS, Holmes MH, Lai WM, Mow VC. Boundary conditions at the cartilage-synovial fluid interface for joint lubrication and theoretical verifications. J Biomech Eng. February 1989;111(1):78-87.
1990	Farquhar T, Dawson PR, Torzilli PA. A microstructural model for the anisotropic drained stiffness of articular cartilage. J Biomech Eng. November 1990;112(4):414-425.
1991	Lai WM, Hou JS, Mow VC. A triphasic theory for the swelling and deformation behaviors of articular cartilage. J Biomech Eng. August 1991;113(3):245-258.
1993	Mow VC, Ateshian GA, Spilker RL. Biomechanics of diarthrodial joints: a review of twenty years of progress. J Biomech Eng. November 1993;115(4B):460-467.
1995	Buschmann MD, Grodzinsky AJ. A molecular model of proteoglycan-associated electrostatic forces in cartilage mechanics. J Biomech Eng. May 1995;117(2):179-192.
1998	Gu WY, Lai WM, Mow VC. A mixture theory for charged-hydrated soft tissues containing multi-electrolytes: passive transport and swelling behaviors. J Biomech Eng. April 1998;120(2):169-180.
1998	Setton LA, Tohyama H, Mow VC. Swelling and curling behaviors of articular cartilage. J Biomech Eng. June 1998;120(3):355-361.
2000	Lai WM, Mow VC, Sun DD, Ateshian GA. On the electric potentials inside a charged soft hydrated biological tissue: streaming potential versus diffusion potential. J Biomech Eng. August 2000;122(4):336-346.
2002	Wang CC-B, Deng J-M, Ateshian GA, Hung CT. An automated approach for direct measurement of two-dimensional strain distributions within articular cartilage under unconfined compression. J Biomech Eng. October 2002;124(6):557-567.
2003	Krishnan R, Park S, Eckstein F, Ateshian GA. Inhomogeneous cartilage properties enhance superficial interstitial fluid support and frictional properties, but do not provide a homogeneous state of stress. J Biomech Eng. October 2003;125(5):569-577.
2003	Mauck RL, Hung CT, Ateshian GA. Modeling of neutral solute transport in a dynamically loaded porous permeable gel: implications for articular cartilage biosynthesis and tissue engineering. J Biomech Eng. October 2003;125(5):602-614.
2004	Sun DD, Guo XE, Likhitpanichkul M, Lai WM, Mow VC. The influence of the fixed negative charges on mechanical and electrical behaviors of articular cartilage under unconfined compression. J Biomech Eng. February 2004;126(1):6-16.
2004	Leddy HA, Awad HA, Guilak F. Molecular diffusion in tissue-engineered cartilage constructs: effects of scaffold material, time, and culture conditions. J Biomed Mater Res. August 15, 2004;B70(2):397-406.
1993	Urban JPG, Hall AC, Gehl KA. Regulation of matrix synthesis rates by the ionic and osmotic environment of articular chondrocytes. J Cell Physiol. February 1993;154(2):262-270.
1995	Buschmann MD, Gluzband YA, Grodzinsky AJ, Hunziker EB. Mechanical compression modulates matrix biosynthesis in chondrocyte/agarose culture. J Cell Sci. April 1995;108(4):1497-1508.
2005	Jadin KD, Wong BL, Bae WC, Li KW, Williamson AK, Schumacher BL, Price JH, Sah RL. Depth-varying density and organization of chondrocytes in immature and mature bovine articular cartilage assessed by 3D imaging and analysis. J Histochem Cytochem. September 2005;53(9):1109-1119.
1983	Hoch DH, Grodzinsky AJ, Koob TJ, Albert ML, Eyre DR. Early changes in material properties of rabbit articular cartilage after meniscectomy. J Orthop Res. 1983;1(1):4-12.
1985	Eisenberg SR, Grodzinsky AJ. Swelling of articular cartilage and other connective tissues: electromechanochemical forces. J Orthop Res. 1985;3(2):148-159.
1986	Schneiderman R, Keret D, Maroudas A. Effects of mechanical and osmotic pressure on the rate of glycosaminoglycan synthesis in the human adult femoral head cartilage: an in vitro study. J Orthop Res. 1986;4(4):393-408.
1987	Akizuki S, Mow VC, Muller F, Pita JC, Howell DS. Tensile properties of human knee joint cartilage, II: correlations between weight bearing and tissue pathology and the kinetics of swelling. J Orthop Res. 1987;5(2):173-186.
1987	Frank EH, Grodzinsky AJ, Koob TJ, Eyre DR. Streaming potentials: a sensitive index of enzymatic degradation in articular cartilage. J Orthop Res. 1987;5(4):497-508.
1988	Gray ML, Pizzanelli AM, Grodzinsky AJ, Lee RC. Mechanical and physicochemical determinants of the chondrocyte biosynthetic response. J Orthop Res. November 1988;6(6):777-792.
1990	Schmidt MB, Mow VC, Chun LE, Eyre DR. Effects of proteoglycan extraction on the tensile behavior of articular cartilage. J Orthop Res. May 1990;8(3):353-363.
1993	Zhu W, Mow VC, Koob TJ, Eyre DR. Viscoelastic shear properties of articular cartilage and the effects of glycosidase treatments. J Orthop Res. November 1993;11(6):771-781.
1994	Guilak F, Ratcliffe A, Lane N, Rosenwasser MP, Mow VC. Mechanical and biochemical changes in the superficial zone of articular cartilage in canine experimental osteoarthritis. J Orthop Res. July 1994;12(4):474-484.
1995	Guilak F, Ratcliffe A, Mow VC. Chondrocyte deformation and local tissue strain in articular cartilage: a confocal microscopy study. J Orthop Res. May 1995;13(3):410-421.
1995	Smith RL, Donlon BS, Gupta MK, Mohtai M, Das P, Carter DR, Cooke J, Gibbons G, Hutchinson N, Schurman DJ. Effects of fluid-induced shear on articular chondrocyte morphology and metabolism in vitro. J Orthop Res. November 1995;13(6):824-831.
1996	Sah RL, Trippel SB, Grodzinsky AJ. Differential effects of serum, insulin-like growth factor-I, and fibroblast growth factor-2 on the maintenance of cartilage physical properties during long-term culture. J Orthop Res. January 1996;14(1):44-52.
1997	Schinagl RM, Gurskis D, Chen AC, Sah RL. Depth-dependent confined compression modulus of full-thickness bovine articular cartilage. J Orthop Res. July 1997;15(4):499-506.
2000	LeRoux MA, Arokoski J, Vail TP, Guilak F, Hyttinen MM, Kiviranta I, Setton LA. Simultaneous changes in the mechanical properties, quantitative collagen organization, and proteoglycan concentration of articular cartilage following canine meniscectomy. J Orthop Res. May 2000;18(3):383-392.
2000	Treppo S, Koepp H, Quan EC, Cole AA, Kuettner KE, Grodzinsky AJ. Comparison of biomechanical and biochemical properties of cartilage from human knee and ankle pairs. J Orthop Res. September 2000;18(5):739-748.
2001	Williamson AK, Chen AC, Sah RL. Compressive properties and function—composition relationships of developing bovine articular cartilage. J Orthop Res. November 2001;19(6):1113-1121.
2002	Thibault M, Poole AR, Buschmann MD. Cyclic compression of cartilage/bone explants in vitro leads to physical weakening, mechanical breakdown of collagen and release of matrix fragments. J Orthop Res. November 2002;20(6):1265-1273.
2004	Darling EM, Hu JCY, Athanasiou KA. Zonal and topographical differences in articular cartilage gene expression. J Orthop Res. November 2004;22(6):1182-1187.
2005	Darling EM, Athanasiou KA. Rapid phenotypic changes in passaged articular chondrocyte subpopulations. J Orthop Res. March 2005;23(2):425-432.
2022	Moo EK, Al-Saffar Y, Le T, Seerattan RA, Pingguan-Murphy B, Korhonen RK, Herzog W. Deformation behaviors and mechanical impairments of tissue cracks in immature and mature cartilages. J Orthop Res. September 2022;40(9):2103-2112.
2024	Moo EK, Sibole SC, Federico S, Korhonen RK, Herzog W. Microscale investigation of the anisotropic swelling of cartilage tissue and cells in response to hypo-osmotic challenges. J Orthop Res. January 2024;42(1):54-65.
1998	Cohen NP, Foster RJ, Mow VC. Composition and dynamics of articular cartilage: structure, function, and maintaining healthy state. J Orthop Sports Phys Ther. October 1998;28(4):203-215.
2003	Ng L, Grodzinsky AJ, Patwari P, Sandy J, Plaas A, Ortiz C. Individual cartilage aggrecan macromolecules and their constituent glycosaminoglycans visualized via atomic force microscopy. J Struct Biol. September 2003;143(3):242-257.
1994	Guilak F, Meyer BC, Ratcliffe A, Mow VC. The effects of matrix compression on proteoglycan metabolism in articular cartilage explants. Osteoarthritis Cartilage. June 1994;2(2):91-101.
1997	Froimson MI, Ratcliffe A, Gardner TR, Mow VC. Differences in patellofemoral joint cartilage material properties and their significance to the etiology of cartilage surface fibrillation. Osteoarthritis Cartilage. November 1997;5(6):377-386.
1999	Setton LA, Elliott D., Mow VC. Altered mechanics of cartilage with osteoarthritis: human osteoarthritis and an experimental model of joint degeneration. Osteoarthritis Cartilage. January 1999;7(1):2-14.
1999	Mow VC, Wang CC, Hung CT. The extracellular matrix, interstitial fluid and ions as a mechanical signal transducer in articular cartilage. Osteoarthritis Cartilage. January 1999;7(1):41-58.
1999	Guilak F, Jones WR, Ting-Beall HP, Lee GM. The deformation behavior and mechanical properties of chondrocytes in articular cartilage. Osteoarthritis Cartilage. January 1999;7(1):59-70.
2001	Chen SS, Falcovitz YH, Schneiderman R, Maroudas A, Sah RL. Depth-dependent compressive properties of normal aged human femoral head articular cartilage: relationship to fixed charge density. Osteoarthritis Cartilage. August 2001;9(6):561-569.
1989	Roberts S, Menage J, Urban JPG. Biochemical and structural properties of the cartilage end-plate and its relation to the intervertebral disc. Spine. February 1989;14(2):166-174.
1996	Roberts S, Urban JPG, Evans H, Eisenstein SM. Transport properties of the human cartilage endplate in relation to its composition and calcification. Spine. March 15, 1996;21(4):415-420.
1999	Gu WY, Mao XG, Foster RJ, Weidenbaum M, Mow VC, Rawlins BA. The anisotropic hydraulic permeability of human lumbar anulus fibrosus: influence of age, degeneration, direction, and water content. Spine. December 1, 1999;24(23):2449-2455.
2009	Fox AJS, Bedi A, Rodeo SA. The basic science of articular cartilage: structure, composition, and function. Sports Health. November–December 2009;1(6):461-468.
2019	Shegaf A. Cartilage Biomechanical and Mechanobiological Response to Sliding Contact [PhD thesis]. Carleton University; August 2019.
2001	Smith CL. Some Aspects of the Biomechanics of Articular Cartilage Repair [PhD thesis]. Cleveland, OH: Case Western Reserve University; May 2001.
1989	Athanasiou KA. Biomechanical Assessment of Articular Cartilage Healing and Interspecies Variability [PhD thesis]. Columbia University; 1989.
1993	Setton LA. Effects of Intrinsic Viscoelasticity and Ion-Induced Swelling on the Mechanical Behavior of Articular Cartilage: Theory and Experiments [PhD thesis]. Columbia University; 1993.
1994	Gu W. A Study of Mechano-Electrokinetic Properties of Charged-Hydrated-Soft Tissues and Biomechanics of Articular Cartilage [PhD thesis]. Columbia University; 1994.
2000	Soltz MA. Investigation of a Boundary Friction Model for Articular Cartilage: Effects of Interstitial Fluid Pressurization and Surface Topography [PhD thesis]. Columbia University; 2000.
2001	Huang C-Y. Biomechanics of Soft Tissues in the Shoulder Joint: Glenohumeral Cartilage, Ligament, and Rotator Cuff Tendon [PhD thesis]. Columbia University; 2001.
2001	Wang C. Digital Video Microscopy-Based Determination of Cartilage Inhomogeneity, Anisotropy and Tension -Compression Nonlinearity: Implications on Chondrocyte Environment [PhD thesis]. Columbia University; 2001.
2002	Sun D. Theoretical and Experimental Investigations of the Mechano-Electrochemical Properties of Articular Cartilage, a Charged -Hydrated -Soft, Biological Tissue [PhD thesis]. Columbia University; 2002.
2003	Mauck RL. Functional Tissue Engineering of Articular Cartilage: The Effect of Physical Forces on the in Vitro Growth of Engineered Constructs [PhD thesis]. Columbia University; 2003.
2004	Krishnan R. Role of Interstitial Fluid Pressurization in Articular Cartilage Lubrication [PhD thesis]. Columbia University; 2004.
2005	Chao P-hG. Physical Forces on Cells: Effects of Applied Osmotic Loading and Direct Current Electric Fields [PhD thesis]. Columbia University; 2005.
2005	Park S. Interstitial Fluid Flow-Dependent and Flow-Independent Mechanical and Tribological Response of Articular Cartilage [PhD thesis]. Columbia University; 2005.
2006	Basalo Perez-Luna IM. Effects of Enzymatic Degradation and Supplementation of Chrondroitin Sulfate on the Frictional Properties of Articular Cartilage [PhD thesis]. Columbia University; 2006.
2006	Chahine NO. Multi-Scale Measurements of the Mechanical and Transport Properties of Native and Engineered Articular Cartilage [PhD thesis]. Columbia University; 2006.
2007	Likhitpanichkul M. The Cell-Matrix Mechano-Electrochemical Interactions in Articular Cartilage: Experiment and Triphasic Model [PhD thesis]. Columbia University; 2007.
2007	Lu X. Indentation Analysis of Articular Cartilage Using the Triphasic Mixture Theory [PhD thesis]. Columbia University; 2007.
2007	Wan Q. Fundamental Theoretical and Experimental Studies for Applications Toward Functional Tissue Engineering of Articular Cartilage [PhD thesis]. Columbia University; 2007.
2008	Ng KW. Biomimetic Engineered Cartilage: Recreating the in Vivo Collagen Network and Depth-Dependent Inhomogeneity [PhD thesis]. Columbia University; 2008.
2009	Canal Guterl C. Contact Mechanics of Articular Layers: 2D Strain Fields and Their Relation to Tissue Inhomogeneity [PhD thesis]. Columbia University; 2009.
2014	Sampat SR. Optimization of Culture Conditions for Cartilage Tissue Engineering Using Synovium-Derived Stem Cells [PhD thesis]. Columbia University; 2014.
2016	Cigan AD. Nutrient Channels to Aid the Growth of Articular Surface-Sized Engineered Cartilage Constructs [PhD thesis]. Columbia University; 2016.
2017	Jones BK. Articular Cartilage Contact Mechanics and Development of a Bendable Osteochondral Allograft [PhD thesis]. Columbia University; 2017.
2020	Zimmerman BKL. Mechanically Mediated Fatigue Failure in Articular Cartilage: Experimental, Theoretical, and Computational Models [PhD thesis]. Columbia University; 2020.
2017	Doyran Sitik B. Nanoscale Structure-Mechanics Principles of Murine Joint Tissues [PhD thesis]. Drexel University; April 2017.
2018	Li Q. Role of Meniscus Micromechanics in Joint Function and Osteoarthritis [PhD thesis]. Drexel University; December 2018.
2019	Chery DR. Biomechanics of the Pericellular Matrix: Roles in Cartilage Development and Osteoarthritis [PhD thesis]. Drexel University; January 2019.
2020	Han B. Decorin Regulates the Structure and Biomechanical Functions of Articular Cartilage Extracellular Matrix in Health and Disease [PhD thesis]. Drexel University; October 2020.
2021	Petrovic MI. Extracellular Matrix Engineering of Porcine Bioprosthetic Heart Valves [Master's thesis]. Drexel University; May 2021.
2000	Narmoneva DA. Material Property Determination for Normal and Osteoarthritic Articular Cartilage Using a Triphasic Mechano -Chemical Theoretical Model of Osmotic Loading [PhD thesis]. Duke University; 2000.
2007	Leddy HA. Diffusional Properties of Articular Cartilage [PhD thesis]. Duke University; 2007.
2009	Christensen SE. The Role of Collagen VI in the Structure and Properties of the Knee Joint [PhD thesis]. Duke University; 2009.
2016	Schätti OR. A Model to Study Articular Cartilage Mechanical and Biological Responses to Sliding and Rolling Loads [PhD thesis]. Swiss Federal Institute of Technology Zürich; 2016.
2007	Palmer AW. Investigations of the Composition-Function Relationships in Normal, Degraded, and Engineered Articular Cartilage Using Epic-Microcomputed Tomography [PhD thesis]. Atlanta, GA: Georgia Institute of Technology; May 2007.
2004	Yao H. Physical Signals and Solute Transport in Cartilaginous Tissues [PhD thesis]. University of Miami; August 2004.
2009	Travascio F. Modeling Molecular Transport and Binding Interactions in Intervertebral Disc [PhD thesis]. University of Miami; December 2009.
2011	Yuan T-Y. Innovative Methods to Determine Material Properties of Cartilaginous Tissues and Application for Tissue Engineering [PhD thesis]. University of Miami; August 2011.
2016	Gao X. Modeling the Biomechanics and Mechanobiology of Intervertebral Discs [PhD thesis]. University of Miami; August 2016.
2017	Kleinhans KL. Transport Properties in Porcine Meniscus Fibrocartilage [PhD thesis]. University of Miami; August 2017.
1983	Eisenberg SR. Nonequilibrium Electromechanical Interactions in Cartilage: Swelling and Electrokinetics Cambridge, MA: Massachusetts Institute of Technology; February 1983.
1986	Gray ML. Physical Regulation of Epiphyseal Cartilage Biosynthesis: Responses to Electrical, Mechanical, and Chemical Signals [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; July 1986.
1987	Frank EH. Electromechanics of Normal and Degenerated Cartilage: Poroelastic Behavior and Electrokinetic Mechanisms [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; May 1987.
1987	Sachs JR. A Mathematical Model of an Electromechanically Coupled Poroelastic Medium [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; June 1987.
1988	MacGinitie LA. Electrical and Thermal Modulation of Protein Synthesis in Cartilage: A Model for Field Effects on Biological Tissues [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; January 1988.
1990	Sah RL-Y. Biophysical Regulation of Matrix Systhesis, Assembly, and Degradation in Dynamically Compressed Calf Cartilage [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; 1990.
1993	Lesperance LM. Compositional Studies of Cartilage Matrix Using NMR Spectroscopy [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; September 1993.
1995	Bashir A. Sodium NMR Relaxation Parameters in Cartilage: Implications for MR Imaging [Master's thesis]. Cambridge, MA: Massachusetts Institute of Technology; 1995.
1995	Bonassar LJ. Matrix Metalloproteinase Activity and Inhibition in Articular Cartilage: Effects on Composition and Biophysical Properties and Relevance to Osteoarthritis [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; February 1995.
1996	Berkenblit SI. Spatial Localization of Cartilage Degradation Using Electromechanical Surface Spectroscopy With Variable Wavelength and Frequency [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; June 1996.
1996	García AM. Mechanisms of Macromolecular Transport Through Articular Cartilage: Relevance to Loading [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; June 1996.
1999	Treppo S. Physical Diagnostics of Cartilage Degeneration [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; February 1999.
2003	Seog J. Molecular Mechanics of Cartilage: Quantification of GAG Electrostatic Interactions Via High-Resolution Force Spectroscopy Cambridge, MA: Massachusetts Institute of Technology; June 2003.
2005	Dean DMD. Modeling and Measurement of Intermolecular Interaction Forces Between Cartilage ECM Macromolecules [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; February 2005.
2005	Ng LJ. Probing Nanomechanics of Aggrecan and the Aggrecan-Rich Pericellular Matrix of Chondrocytes in Cartilage [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; September 2005.
2005	Szafranski JD. Cartilage Mechanobiology: The Effects of Loading on the Fine Structure and Function of Chondroitin Sulfate Glycosaminoglycans [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; June 2005.
2007	Han L. Nanomechanics of Cartilage Extracellular Matrix Macromolecules [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; September 2007.
2007	Wu BYC. Investigation of Long-Term Cyclic Loading Effects on Initially Intact Cartilage [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; September 2007.
2008	Chai DH. Progression of Chondrocyte Signaling Responses to Mechanical Stimulation in 3-D Gel Culture [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; February 2008.
2008	Wheeler CA. Cartilage Response to in Vitro Models of Injury in Combination With Growth Factor and Antioxidant Treatments [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; February 2008.
2009	Chen S. Regulation of Lubricin Gene Expression and Synthesis in Cartilage by Mechanical Injury [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; September 2009.
2010	Byun S. Transport of Proteins, Biopharmaceuticals and Small Pharmaceutical Compounds Into Normal and Injured Cartilage [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; June 2010.
2013	Nia HT. Nanomechanics of Cartilage At the Matrix and Molecular Levels [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; June 2013.
2016	Liebesny PH. Single-Dose Growth Factor Treatments to Enhance Cell Recruitment and Neotissue Integration in an Augmented Microfracture Cartilage Repair Model [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; June 2016.
1992	Ide TM. An Analysis of Impact-Induced Trauma to Articular Cartilage [Master's thesis]. East Lansing, MI: Michigan State University; 1992.
2009	Golenberg N. Investigations on the Effects of Cyclic Loading and Therapeutic Treatments Following Traumatic Injury to Articular Cartilage [Master's thesis]. East Lansing, MI: Michigan State University; 2009.
2002	Stile RA. Injectable Thermo-Responsive Hydrogels Capable of Cell- and Tissue-Specific Interactions [PhD thesis]. Evanston, IL: Northwestern University; June 2002.
2000	Langelier E. Le rôle du cytosquelette dans la mécanique des cellules du cartilage, les chondrocytes [PhD thesis]. École polytechnique de Montréal; December 2000.
2003	Willett TL. The Depth- and Strain-Dependent Electro-Mechanical Properties of Porcine Articular Cartilage [Master's thesis]. Queen's University; May 2003.
2011	Bow JK. Using Adenosine Triphosphate (ATP) as a Substitute for Mechanical Stimulation for Tissue Engineering Applications [Master's thesis]. Queen's University; January 2011.
2016	Levett PA. Photocrosslinkable Hydrogels for Cartilage Tissue Engineering [PhD thesis]. Queensland University of Technology; 2016.
2018	Arabshahi Z. New Mechanical Indentation Framework for Functional Assessment of Articular Cartilage [PhD thesis]. Queensland University of Technology; 2018.
2004	Darling EM. Phenotype of Passaged, Zonal Articular Chondrocytes [PhD thesis]. Houston, TX: Rice University; July 2004.
2004	Detamore MS. Characterization and Tissue Engineering of the Temporomandibular Joint Disc [PhD thesis]. Houston, TX: Rice University; July 2004.
2005	Almarza AJ. Extracellular Matrix Characterization and Tissue Engineering of the Temporomandibular Joint Disc [PhD thesis]. Houston, TX: Rice University; April 2005.
2005	Hu J. Chondrocyte Self -Assembly and Culture in Bioreactors [PhD thesis]. Houston, TX: Rice University; April 2005.
1985	Kwan MK-W. A Finite Deformation Theory for Nonlinearly Permeable Cartilage and Other Soft Hydrated Connective Tissues and Rheological Study of Cartilage Proteoglycans [PhD thesis]. Troy, NY: Rensselaer Polytechnic Institute; December 1985.
1989	Suh J-K. A Finite Element Formulation for Nonlinear Behavior of Biphasic Hydrated Soft Tissues Under Finite Deformation [PhD thesis]. Troy, NY: Rensselaer Polytechnic Institute; September 1989.
1995	Hejna MJ. Isolation and Characterization of Peptides Bearing the Epitope for Monoclonal Antibody 1-C-6 from Swarm Rat Chondrosarcoma Proteoglycan [PhD thesis]. Rush University; 1995.
1990	Wong M. The Role of Mechanical Loading Histories in Skeletal Morphogenesis [PhD thesis]. Stanford University; June 1990.
1996	Mikic B. Epigenetic Influences on Long Bone Growth, Development, and Evolution [PhD thesis]. Stanford University; June 1996.
1997	Wren TAL. Structure-Function Relationships for Soft Skeletal Connective Tissues [PhD thesis]. Stanford University; June 1997.
2000	Sarin VK. Mechanobiology of Sesamoid Formation, Development, and Ossification [PhD thesis]. Stanford University; May 2000.
2017	Monu UD. Visualization and Evaluation Tools of Quantitative MRI in an ACL-Injured Population [PhD thesis]. Stanford University; August 2017.
2018	Baylon EG. Isn’t it Swell? The Effect of Osmotic Swelling on Articular Cartilage and Meniscal Fibrocartilage Mechanics and Diagnostic Approaches [PhD thesis]. Stanford University; March 2018.
1992	Van der Voet AF. Finite Element Modelling of Load Transfer Through Articular Cartilage [PhD thesis]. Calgary, AB: University of Calgary; August 1992.
2000	Kralovic BJ. The Effects of Patellofemoral Kinematics on Joint Congruence and Cartilage Stresses [Master's thesis]. Calgary, AB: University of Calgary; January 2000.
2003	Han S-K. Articular Cartilage Modeling in the 3-D Patellofemoral Joint Contact [Master's thesis]. Calgary, AB: University of Calgary; June 2003.
2014	Jablonski CL. Integrin Α1β1 Participates in Chondrocyte Transduction of Osmotic Stress [Master's thesis]. Calgary, AB: University of Calgary; May 2014.
2015	Lee JK. Bioactive and Mechanical Stimuli for Engineering Neocartilage With Native Tissue-Like Tensile Properties [PhD thesis]. Davis, University of California; 2015.
1997	Chen AC. Electromechanical Properties of Normal Cartilage and Biomechanical Regulation of Transplanted Chondrocytes: Implications for Articular Cartilage Tissue Engineering [PhD thesis]. San Diego (UCSD), University of California; 1997.
1997	Schinagl RM. Depth-Dependent Compressive Properties and Cell Adhesion in Articular Cartilage Repair [PhD thesis]. San Diego (UCSD), University of California; 1997.
1998	Ahsan T. Integrative Repair and Collagen Crosslinking in Articular Cartilage [PhD thesis]. San Diego (UCSD), University of California; 1998.
1999	Chang DG. Structure and Function Relationships of Articular Cartilage in Osteoarthritis [PhD thesis]. San Diego (UCSD), University of California; 1999.
2001	DiMicco MA. Collagen Synthesis, Transport, and Deposition in Integrative Articular Cartilage Repair [PhD thesis]. San Diego (UCSD), University of California; 2001.
2002	Li KW. Regulation of Chondrocytes by Static and Dynamic Loading in Articular Cartilage Repair [PhD thesis]. San Diego (UCSD), University of California; 2002.
2002	Williamson AK. Development and Growth of Bovine Articular Cartilage: Biomechanical Function and Function-Composition Relationships [PhD thesis]. San Diego (UCSD), University of California; 2002.
2004	Bae WC. Indentation Testing of Articular Cartilage: Biomechanics and Efficacy [PhD thesis]. San Diego (UCSD), University of California; 2004.
2005	Klein TJ. Cartilage Tissue Engineering: Biophysical Modulation of Functional Depth-Dependent Properties [PhD thesis]. San Diego (UCSD), University of California; 2005.
2005	McGowan KB. Enhancement of Integrative Cartilage Repair by Manipulation of Extracellular Matrix [PhD thesis]. San Diego (UCSD), University of California; 2005.
2005	Temple MM. Age- and Site-Associated Biomechanical Weakening of Human Articular Cartilage: Relationship to Cellularity, Wear, Matrix Fragmentation and the Progression to Osteoarthritis [PhD thesis]. San Diego (UCSD), University of California; 2005.
2006	Asanbaeva A. Cartilage Growth and Remodeling: Modulation of Growth Phenotype and Tensile Integrity [PhD thesis]. San Diego (UCSD), University of California; 2006.
2006	Chawla K. Mechanisms of Articular Cartilage Defect Repair in Vivo After Implantation of Stratified Cartilaginous Tissue [PhD thesis]. San Diego (UCSD), University of California; 2006.
2006	Jadin KD. Mechanisms of Growth of Articular Cartilage: Cell Organization and Fates [PhD thesis]. San Diego (UCSD), University of California; 2006.
2006	Nugent GE. Biomechanical Regulation of Articular Cartilage Metabolism of Proteoglycan 4 and Articular Surface Integrity [PhD thesis]. San Diego (UCSD), University of California; 2006.
2006	Schmidt TA. Proteoglycan 4 Metabolism and Boundary Lubrication of Articular Cartilage [PhD thesis]. San Diego (UCSD), University of California; 2006.
2009	Hsieh-Bonassera ND. Cartilage Tissue Engineering With Human Chondrocytes from Osteoarthritic Knees and a Semi-Permeable Membrane [PhD thesis]. San Diego (UCSD), University of California; 2009.
2009	Wong BL. Biomechanics of Cartilage Articulation: Effects of Degeneration, Lubrication, and Focal Articular Defects [PhD thesis]. San Diego (UCSD), University of California; 2009.
2010	Hwang J. Integration of Cartilage and Bone Through a Calcified Cartilage Interface to Form a Functional Osteochondral Graft [PhD thesis]. San Diego (UCSD), University of California; 2010.
2010	Williams GM. Biophysical and Biochemical Regulation of the Shape, Size, and Maturity of Calf Articular Cartilage [PhD thesis]. San Diego (UCSD), University of California; 2010.
2011	Antonacci JM. Boundary Lubrication of Articular Cartilage: Contribution of Hyaluronan in Health and Injury [PhD thesis]. San Diego (UCSD), University of California; 2011.
2011	Han E. Tissue Engineering of Cartilaginous Grafts With Mechanically Functional Aggrecan [PhD thesis]. San Diego (UCSD), University of California; 2011.
2012	McCarty WJ. Synovial Fluid Homeostasis: Bulk Flow, Lubricant Transport, and Biophysical Restoration [PhD thesis]. San Diego (UCSD), University of California; 2012.
2012	Nguyen QT. Mechanobiology and Biomechanics of Articular Cartilage Repair [PhD thesis]. San Diego (UCSD), University of California; 2012.
2016	Chang N. Structural Deterioration of Human Articular Cartilage and Subchondral Plate [PhD thesis]. San Diego (UCSD), University of California; 2016.
2018	Raleigh A. Biophysical Mechanisms of Disturbances to Synovial Joint Lubricant Homeostasis in Post-Traumatic Osteoarthritis [PhD thesis]. San Diego (UCSD), University of California; 2018.
2000	Fedewa MM. Determinants of Microstructural Load Transfer in Cartilage Tissue from Chondrocyte Culture [PhD thesis]. University of Minnesota; August 2000.
2015	Robinson DL. Mechanical Properties of Normal and Osteoarthritic Human Articular Cartilage [PhD thesis]. University of Melbourne; 2015.
2011	Erickson IE. Optimization and Translation of MSC-Based Hyaluronic Acid Hydrogels for Cartilage Repair [PhD thesis]. Philadelphia, PA: University of Pennsylvania; 2011.
2007	Anderson AE. Computational Modeling of Hip Joint Mechanics [PhD thesis]. University of Utah; April 2007.
1998	Mukherjee N. Load Sharing in Articular Cartilage [PhD thesis]. Richmond, VA: Virginia Commonwealth University; August 1998.

Year	Entry
1968	Maroudas A. Physicochemical properties of cartilage in the light of ion exchange theory. Biophys J. May 1968;8(5):575-595.
1970	Maroudas A. Distribution and diffusion of solutes in articular cartilage. Biophys J. May 1970;10(5):365-379.
1977	Maroudas A, Venn M. Chemical composition and swelling of normal and osteoarthrotic femoral head cartilage, II: swelling. Ann Rheum Dis. 1977;36(5):399-406.
1976	Maroudas A. Balance between swelling pressure and collagen tension in normal and degenerate cartilage. Nature. April 29, 1976;260(5554):808-809.
1976	Mansour JM, Mow VC. The permeability of articular cartilage under compressive strain and at high pressures. J Bone Joint Surg. June 1976;58A(4):509-516.
1970	Muir H, Bullough P, Maroudas A. The distribution of collagen in human articular cartilage with some of its physiological implications. J Bone Joint Surg. August 1970;52B(3):554-563.
1969	Maroudas A, Muir H, Wingham J. The correlation of fixed negative charge with glycosaminoglycan content of human articular cartilage. Biochim Biophys Acta. May 6, 1969;177(3):492-500.
1962	McCutchen CW. The frictional properties of animal joints. Wear. January–February 1962;5(1):1-17.
1965	Linn FC, Sokoloff L. Movement and composition of interstitial fluid of cartilage. Arthritis Rheum. August 1965;8(4):481-494.
1977	Urban JPG. Fluid and Solute Transport in the Inter-Vertebral Disc [PhD thesis]. Imperial College London; June 1977.
1976	Torzilli PA, Mow VC. On the fundamental fluid transport mechanisms through normal and pathological articular cartilage during function, I: the formulation. J Biomech. 1976;9(8):541-552.
1977	Venn M, Maroudas A. Chemical composition and swelling of normal and osteoarthrotic femoral head cartilage, I: chemical composition. Ann Rheum Dis. 1977;36(2):121-129.