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Fox, Alice J. Sophia
1
; Bedi, Asheesh
2
;
Rodeo, Scott A.
2
The basic science of articular cartilage: structure, composition, and function
Sports Health
. November–December 2009;1(6):461-468
©2009 The Author(s)
Affiliations
1
Laboratory of Soft Tissue Research,
Hospital for Special Surgery
, New York, New York
2
Sports Medicine and Shoulder Service,
Hospital for Special Surgery
, New York, New York
Keywords
Keywords:
articular cartilage; basic science; extracellular matrix; collagen; proteoglycan; chondrocyte
Links
DOI:
10.1177/1941738109350438
PubMed:
23015907
PubMedCentral:
PMC3445147
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Cited By (141)
Year
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2025
Zila L, Tarantino R, Zastawny P, Waldman SD. Dynamic compression modulates anabolic and catabolic activity in chondrocyte seeded agarose constructs.
J Biomech
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2022
Finnilä MAJ, Gupta SD, Turunen MJ, Hellberg I, Turkiewicz A, Lutz-Bueno V, Jonsson E, Holler M, Ali N, Hughes V, Isaksson H, Tjörnstrand J, Önnerfjord P, Guizar-Sicairos M, Saarakkala S, Englund M. Mineral crystal thickness in calcified cartilage and subchondral bone in healthy and osteoarthritic human knees.
J Bone Miner Res
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2022
Liu H, Witzigreuter L, Sathiaseelan R, Agbaga M-P, Brush RS, Stout MB, Zhu S. Obesity promotes lipid accumulation in mouse cartilage: a potential role of acetyl-CoA carboxylase (ACC) mediated chondrocyte de novo lipogenesis.
J Orthop Res
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2025
Hamada M, Eskelinen ASA, Florea C, Mikkonen S, Nieminen P, Grodzinsky AJ, Tanska P, Korhonen RK. Loss of collagen content is localized near cartilage lesions on the day of injurious loading and intensified on day 12.
J Orthop Res
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2025
Cruz MA, Gronowicz S, Karimzadeh M, Martyniak K, Medam R, Kean TJ. Disease modifying osteoarthritis drug discovery using a temporal phenotypic reporter in 3D aggregates of primary human chondrocytes.
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2020
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2021
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2013
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2014
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2020
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2018
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2019
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2018
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2018
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2019
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Quantitative Imaging of Cartilage and Meniscus for Detection of Early Osteoarthritic Degeneration
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2021
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2021
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2019
Knowles NK.
Improving Material Mapping in Glenohumeral Finite Element Models: A Multi-Level Evaluation
[PhD thesis]. University of Western Ontario; 2019.
2022
Benitah J.
The Effects of a Porous Internal Lattice Design on the Articular Contact Mechanics of Radial Head Hemiarthroplasty Implants
[Master's thesis]. University of Western Ontario; 2022.
2022
Liubchak I.
Conducting Polypyrrole Hydrogel Biomaterials for Drug Delivery and Cartilage Tissue Regeneration
[Master's thesis]. University of Western Ontario; 2022.
2019
Han G.
Energy Dissipation and Failure in Articular Cartilage
[PhD thesis]. University of Wisconsin – Madison; 2019.
2020
Walsh SK.
Effects of Age and Mechanical Loading on Articular Cartilage Metabolism and Corresponding Consequences for Tissue Health
[PhD thesis]. University of Wisconsin – Madison; 2020.
2020
Ross A.
Tissue Engineering of Induced Pluripotent Stem Cells for the Development of Novel Treatment Strategies for Osteoarthritis
[PhD thesis]. St. Louis, MO: Washington University in St. Louis; May 2020.
2021
Berke IM.
Evaluating the Structural and Functional Consequences of Traumatic Joint Injury and Their Relation to NF-ΚB in a Non-Invasive Model of Post-Traumatic Osteoarthritis
[PhD thesis]. St. Louis, MO: Washington University in St. Louis; January 2021.
2021
Dicks A.
Human IPSC Tissue-Engineered Cartilage for Disease Modeling of Skeletal Dysplasia-Causing TRPV4 Mutations
[PhD thesis]. St. Louis, MO: Washington University in St. Louis; August 2021.
2021
Katz D.
Understanding and Improving Adult Stem Cells for Cartilage Tissue Engineering
[PhD thesis]. St. Louis, MO: Washington University in St. Louis; August 2021.
2021
Pferdehirt L.
Synthetic Gene Circuits for Self-Regulating and Temporal Delivery of Anti-Inflammatory Biologic Drugs in Engineered Tissues
[PhD thesis]. St. Louis, MO: Washington University in St. Louis; May 2021.
2023
Savadipour A.
Mechanosensitive Ion Channels as Therapeutics Targets for Osteoarthritis
[PhD thesis]. St. Louis, MO: Washington University in St. Louis; December 2023.
2024
Palmer DR.
Defining the Chondrocyte “Mechanome”: How Mechanosensitive Ion Channels TRPV4 and PIEZO1 Drive Changes in Gene Expression to Affect Cell Behavior and Cartilage Health
[PhD thesis]. St. Louis, MO: Washington University in St. Louis; December 2024.