Physicochemical and bioelectrical determinants of cartilage material properties

Frank, E. H.; Grodzinsky, A. J.; Phillips, S. L.; Grimshaw, P. E.

Affiliations

¹Department of Surgery, Faculty of Medicine, University of Calgary HSC, Calgary, Alberta, Canada T2N 4Nl

²Continuum Electromechanics Group, Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, U.S.A.

Links

DOI: 10.1007/978-1-4612-3448-7_9

Cited Works (23)

Year	Entry
1989	Heinegård D, Oldberg Å. Structure and biology of cartilage and bone matrix noncollagenous macromolecules. FASEB J. July 1989;3(9):2042-2051.
1986	Mak AF. The apparent viscoelastic behavior of articular cartilage: the contributions from the intrinsic matrix viscoelasticity and interstitial fluid flows. J Biomech Eng. May 1986;108(2):123-130.
1979	Maroudas A. Physicochemical properties of articular cartilage. In: Freeman MAR, ed. Adult Articular Cartilage. 2nd ed. Kent, England: Pitman Medical; 1979:215-290.
1963	Sokoloff L. Elasticity of articular cartilage: effect of ions and viscous solutions. Science. September 13, 1963;141(3585):1055-1057.
1986	Holmes MH. Finite deformation of soft tissue: analysis of a mixture model in uni-axial compression. J Biomech Eng. November 1986;108(4):372-381.
1985	Holmes MH, Lai WM, Mow VC. Singular perturbation analysis of the nonlinear, flow-dependent compressive stress relaxation behavior of articular cartilage. J Biomech Eng. August 1985;107(3):206-218.
1983	Eisenberg SR. Nonequilibrium Electromechanical Interactions in Cartilage: Swelling and Electrokinetics Cambridge, MA: Massachusetts Institute of Technology; February 1983.
1985	Eisenberg SR, Grodzinsky AJ. Swelling of articular cartilage and other connective tissues: electromechanochemical forces. J Orthop Res. 1985;3(2):148-159.
1987	Eisenberg SR, Grodzinsky AJ. The kinetics of chemically induced nonequilibrium swelling of articular cartilage and corneal stroma. J Biomech Eng. February 1987;109(1):79-89.
1979	Kempson GE. Mechanical properties of articular cartilage. In: Freeman MAR, ed. Adult Articular Cartilage. 2nd ed. Kent, England: Pitman Medical; 1979:333-414.
1984	Armstrong CG, Lai WM, Mow VC. An analysis of the unconfined compression of articular cartilage. J Biomech Eng. May 1984;106(2):165-173.
1963	Elmore SM, Sokoloff L, Norris G, Carmeci P. Nature of “imperfect” elasticity of articular cartilage. J Appl Physiol. 1963;18(2):393-396.
1987	Frank EH, Grodzinsky AJ. Cartilage electromechanics, I: electrokinetic transduction and the effects of electrolyte pH and ionic strength. J Biomech. 1987;20(6):615-627.
1988	Gray ML, Pizzanelli AM, Grodzinsky AJ, Lee RC. Mechanical and physicochemical determinants of the chondrocyte biosynthetic response. J Orthop Res. November 1988;6(6):777-792.
1984	Myers ER, Lai WM, Mow VC. A continuum theory and an experiment for the ion-induced swelling behavior of articular cartilage. J Biomech Eng. May 1984;106(2):151-158.
1980	Mow VC, Kuei SC, Lai WM, Armstrong CG. Biphasic creep and stress relaxation of articular cartilage in compression: theory and experiments. J Biomech Eng. February 1980;102(1):73-84.
1984	Mow VC, Holmes MH, Lai WM. Fluid transport and mechanical properties of articular cartilage: a review. J Biomech. 1984;17(5):377-394.
1986	Nussbaum JH. Electric Field Control of Mechanical and Electrochemical Properties of Polyelectrolyte Gel Membranes Cambridge, MA: Massachusetts Institute of Technology; August 1986.
1979	Urban JPG, Maroudas A. The measurement of fixed charged density in the intervertebral disc. Biochim Biophys Acta. August 6, 1979;586(1):166-178.
1981	Grodzinsky AJ, Roth V, Myers E, Grossman WD, Mow VC. The significance of electromechanical and osmotic forces in the nonequilibrium swelling behavior of articular cartilage in tension. J Biomech Eng. November 1981;103(4):221-231.
1981	Lee RC, Frank EH, Grodzinsky AJ, Roylance DK. Oscillatory compressional behavior of articular cartilage and its associated electromechanical properties. J Biomech Eng. November 1981;103(2):280-292.
1987	Frank EH, Grodzinsky AJ. Cartilage electromechanics, II: a continuum model of cartilage electrokinetics and correlation with experiments. J Biomech. 1987;20(6):629-639.
1987	Frank EH. Electromechanics of Normal and Degenerated Cartilage: Poroelastic Behavior and Electrokinetic Mechanisms [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; May 1987.

Cited By (27)

Year	Entry
2003	Gu WY, Yao H. Effects of hydration and fixed charge density on fluid transport in charged hydrated soft tissues. Ann Biomed Eng. November 2003;31(10):1162-1170.
2000	Grodzinsky AJ, Levenston ME, Jin M, Frank EH. Cartilage tissue remodeling in response to mechanical forces. Annu Rev Biomed Eng. 2000;2:691-713.
1995	Bonassar LJ, Frank EH, Murray JC, Paguio CG, Moore VL, Lark MW, Sandy JD, Wu J-J, Eyre DR, Grodzinsky AJ. Changes in cartilage composition and physical properties due to stromelysin degradation. Arthritis Rheum. February 1995;38(2):173-183.
2009	Ateshian GA. The role of interstitial fluid pressurization in articular cartilage lubrication. J Biomech. June 19, 2009;42(9):1163-1176.
1995	Buschmann MD, Grodzinsky AJ. A molecular model of proteoglycan-associated electrostatic forces in cartilage mechanics. J Biomech Eng. May 1995;117(2):179-192.
1998	Gu WY, Lai WM, Mow VC. A mixture theory for charged-hydrated soft tissues containing multi-electrolytes: passive transport and swelling behaviors. J Biomech Eng. April 1998;120(2):169-180.
2009	Ateshian GA, Rajan V, Chahine NO, Canal CE, Hung CT. Modeling the matrix of articular cartilage using a continuous fiber angular distribution predicts many observed phenomena. J Biomech Eng. June 2009;131(6):061003.
1993	Urban JPG, Hall AC, Gehl KA. Regulation of matrix synthesis rates by the ionic and osmotic environment of articular chondrocytes. J Cell Physiol. February 1993;154(2):262-270.
1992	Buschmann MD, Gluzband YA, Grodzinsky AJ, Kimura JH, Hunziker EB. Chondrocytes in agarose culture synthesize a mechanically functional extracellular matrix. J Orthop Res. November 1992;10(6):745-758.
1996	Sah RL, Trippel SB, Grodzinsky AJ. Differential effects of serum, insulin-like growth factor-I, and fibroblast growth factor-2 on the maintenance of cartilage physical properties during long-term culture. J Orthop Res. January 1996;14(1):44-52.
2000	Treppo S, Koepp H, Quan EC, Cole AA, Kuettner KE, Grodzinsky AJ. Comparison of biomechanical and biochemical properties of cartilage from human knee and ankle pairs. J Orthop Res. September 2000;18(5):739-748.
2015	Wright GJ. Biomechanical Characterization and Modeling of the Human TMJ Disc [PhD thesis]. Clemson, SC: Clemson University; May 2015.
1994	Gu W. A Study of Mechano-Electrokinetic Properties of Charged-Hydrated-Soft Tissues and Biomechanics of Articular Cartilage [PhD thesis]. Columbia University; 1994.
2001	Wang C. Digital Video Microscopy-Based Determination of Cartilage Inhomogeneity, Anisotropy and Tension -Compression Nonlinearity: Implications on Chondrocyte Environment [PhD thesis]. Columbia University; 2001.
2007	Wan Q. Fundamental Theoretical and Experimental Studies for Applications Toward Functional Tissue Engineering of Articular Cartilage [PhD thesis]. Columbia University; 2007.
2004	Yao H. Physical Signals and Solute Transport in Cartilaginous Tissues [PhD thesis]. University of Miami; August 2004.
2017	Kleinhans KL. Transport Properties in Porcine Meniscus Fibrocartilage [PhD thesis]. University of Miami; August 2017.
1993	Lesperance LM. Compositional Studies of Cartilage Matrix Using NMR Spectroscopy [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; September 1993.
1995	Bonassar LJ. Matrix Metalloproteinase Activity and Inhibition in Articular Cartilage: Effects on Composition and Biophysical Properties and Relevance to Osteoarthritis [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; February 1995.
1996	Berkenblit SI. Spatial Localization of Cartilage Degradation Using Electromechanical Surface Spectroscopy With Variable Wavelength and Frequency [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; June 1996.
1996	García AM. Mechanisms of Macromolecular Transport Through Articular Cartilage: Relevance to Loading [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; June 1996.
1999	Treppo S. Physical Diagnostics of Cartilage Degeneration [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; February 1999.
2020	Krishnan Y. Intra/extracellular Multi-Drug Delivery for Osteoarthritis [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; September 2020.
2005	Mesfar W. Biomécanique du genou humain en flexion sous les activités musculaires: Modélisation par la méthode des éléments finis [PhD thesis]. École polytechnique de Montréal; December 2005.
2009	Adouni MBA. Biomécanique de joint du genou durant l'application des exercices à chaîne cinétique fermée (CKC) [Master's thesis]. École polytechnique de Montréal; June 2009.
2012	Marouane H. Effet de la force de compression sur la réponse passive de l'articulation du genou: Une étude numérique non-linéaire [Master's thesis]. École polytechnique de Montréal; November 2012.
1997	Chen AC. Electromechanical Properties of Normal Cartilage and Biomechanical Regulation of Transplanted Chondrocytes: Implications for Articular Cartilage Tissue Engineering [PhD thesis]. San Diego (UCSD), University of California; 1997.