Quantification of bone microarchitecture with the structure model index

Hildebrand, Tor; Rüegsegger, Peter

Year	Entry
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2009	Ohser J, Redenbach C, Schladitz K. Mesh free estimation of the structure model index. Image Anal Stereol. 2009;28(3):179-185.
2010	Parkinson IH, Forbes D, Sutton-Smith P, Fazzalari NL. Model-independent 3D descriptors of vertebral cancellous bone architecture. J Osteopor. 2010;2010:641578.
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2010	Yao X, Wang P, Dai R, Yeh HY. Microstructures and properties of cancellous bone of avascular necrosis of femoral heads. Acta Mech Sin. March 2010;26(1):13-19.
2008	Zhang Y, He Z, Fan S, He K, Li C. Automatic thresholding of micro-CT trabecular bone images. Proceedings of the International Conference on BioMedical Engineering and Informatics (BMEI 2008); May 27-30, 2008; Sanya, Hainan, China.23-27.
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2021	Callens SJP, Tourolle né Betts DC, Müller R, Zadpoor AA. The local and global geometry of trabecular bone. Acta Biomater. August 2021;130:343-361.
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2001	Fajardo RJ, Müller R. Three‐dimensional analysis of nonhuman primate trabecular architecture using micro‐computed tomography. Am J Phys Anthropol. 2001;115(4):327-336.
2003	Cooper DML, Turinsky AL, Sensen CW, Hallgrímsson B. Quantitative 3D analysis of the canal network in cortical bone by micro-computed tomography. Anat Rec. September 2003;274B(1):169-179.
2006	Boyd SK, Moser S, Kuhn M, Klinck RJ, Krauze PL, Müller R, Gasser JA. Evaluation of three-dimensional image registration methodologies for in vivo micro-computed tomography. Ann Biomed Eng. October 2006;34(10):1587-1599.
2007	Burghardt AJ, Kazakia GJ, Majumdar S. A local adaptive threshold strategy for high resolution peripheral quantitative computed tomography of trabecular bone. Ann Biomed Eng. October 2007;235(10):1678-1686.
1998	Müller R, Van Campenhout H, Van Damme B, Van der Perre G, Dequeker J, Hildebrand T, Rüegsegger P. Morphometric analysis of human bone biopsies: a quantitative structural comparison of histological sections and micro-computed tomography. Bone. July 1998;23(1):59-66.
1999	Laib A, Rüegsegger P. Calibration of trabecular bone structure measurements of in vivo three-dimensional peripheral quantitative computed tomography with 28-μm-resolution microcomputed tomography. Bone. January 1999;24(1):35-39.
2000	Ding M, Hvid I. Quantification of age-related changes in the structure model type and trabecular thickness of human tibial cancellous bone. Bone. March 2000;26(3):291-295.
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2002	Hara T, Tanck E, Homminga J, Huiskes R. The influence of microcomputed tomography threshold variations on the assessment of structural and mechanical trabecular bone properties. Bone. July 2002;31(1):107-109.
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2004	Borah B, Dufresne TE, Chmielewski PA, Johnson TD, Chines A, Manhart MD. Risedronate preserves bone architecture in postmenopausal women with osteoporosis as measured by three-dimensional microcomputed tomography. Bone. April 2004;34(4):736-746.
2004	Siu WS, Qin L, Cheung WH, Leung KS. A study of trabecular bones in ovariectomized goats with micro-computed tomography and peripheral quantitative computed tomography. Bone. 2004;35(1):21-26.
2005	Lai YM, Qin L, Yeung HY, Lee KKH, Chan KM. Regional differences in trabecular BMD and micro-architecture of weight-bearing bone under habitual gait loading: a pQCT and microCT study in human cadavers. Bone. 2005;37(2):274-282.
2005	De Souza RL, Matsuura M, Eckstein F, Rawlinson SCF, Lanyon LE, Pitsillides AA. Non-invasive axial loading of mouse tibiae increases cortical bone formation and modifies trabecular organization: a new model to study cortical and cancellous compartments in a single loaded element. Bone. December 2005;37(6):810-818.
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2006	Boyd SK, Davison P, Müller R, Gasser JA. Monitoring individual morphological changes over time in ovariectomized rats by in vivo micro-computed tomography. Bone. October 2006;39(4):854-862.
2007	Buie HR, Campbell GM, Klinck RJ, MacNeil JA, Boyd SK. Automatic segmentation of cortical and trabecular compartments based on a dual threshold technique for in vivo micro-CT bone analysis. Bone. October 2007;41(4):505-515.
2007	Perilli E, Baleani M, Öhman C, Baruffaldi F, Viceconti M. Structural parameters and mechanical strength of cancellous bone in the femoral head in osteoarthritis do not depend on age. Bone. November 2007;41(5):760-768.
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2010	Rubin MR, Dempster DW, Kohler T, Stauber M, Zhou H, Shane E, Nickolas T, Stein E, Sliney J Jr, Silverberg SJ, Bilezikian JP, Müller R. Three dimensional cancellous bone structure in hypoparathyroidism. Bone. January 2010;46(1):190-195.
2010	Shi X, Liu XS, Wang X, Guo XE, Niebur GL. Effects of trabecular type and orientation on microdamage susceptibility in trabecular bone. Bone. May 2010;46(5):1260-1266.
2010	Doube M, Kłosowski MM, Arganda-Carreras I, Cordelières FP, Dougherty RP, Jackson JS, Schmid B, Hutchinson JR, Shefelbine SJ. BoneJ: free and extensible bone image analysis in ImageJ. Bone. December 2010;47(6):1076-1079.
2012	Pialat JB, Burghardt AJ, Sode M, Link TM, Majumdar S. Visual grading of motion induced image degradation in high resolution peripheral computed tomography: impact of image quality on measures of bone density and micro-architecture. Bone. January 2012;50(1):111-118.
2013	Thomsen JS, Niklassen AS, Ebbesen EN, Brüel A. Age-related changes of vertical and horizontal lumbar vertebral trabecular 3D bone microstructure is different in women and men. Bone. November 2013;57(1):47-55.
2014	Dong P, Haupert S, Hesse B, Langer M, Gouttenoire P-J, Bousson V, Peyrin F. 3D osteocyte lacunar morphometric properties and distributions in human femoral cortical bone using synchrotron radiation micro-CT images. Bone. March 2014;60:172-185.
2017	Kroker A, Zhu Y, Manske SL, Barber R, Mohtadi N, Boyd SK. Quantitative in vivo assessment of bone microarchitecture in the human knee using HR-pQCT. Bone. April 2017;97:43-48.
2020	Jin Y, Zhang T, Cheung JPY, Wong TM, Feng X, Sun T, Zu H, Sze KY, Lu WW. A novel mechanical parameter to quantify the microarchitecture effect on apparent modulus of trabecular bone: a computational analysis of ineffective bone mass. Bone. June 2020;135:115314.
2021	Wang L, Hou S, Sabsovich I, Guo T-Z, Wei T, Kingery WS. Mice lacking substance P have normal bone modeling but diminished bone formation, increased resorption, and accelerated osteopenia with aging. Bone. March 2021;144:115806.
2022	Doi M, Chiba K, Okazaki N, Kondo C, Yamada S, Yokota K, Yonekura A, Tomita M, Osaki M. Bone microstructure in healthy men measured by HR-pQCT: age-related changes and their relationships with DXA parameters and biochemical markers. Bone. January 2022;154:116252.
2022	Chiba K, Okazaki N, Kurogi A, Watanabe T, Mori A, Suzuki N, Adachi K, Era M, Yokota K, Inoue T, Yabe Y, Furukawa K, Kondo C, Tsuda K, Ota S, Isobe Y, Miyazaki S, Morimoto S, Sato S, Nakashima S, Tashiro S, Yonekura A, Tomita M, Osaki M. Randomized controlled trial of daily teriparatide, weekly high-dose teriparatide, or bisphosphonate in patients with postmenopausal osteoporosis: the TERABIT study. Bone. July 2022;160:116416.
2022	Goff E, Cohen A, Shane E, Recker RR, Kuhn G, Müller R. Large-scale osteocyte lacunar morphological analysis of transiliac bone in normal and osteoporotic premenopausal women. Bone. July 1, 2022;160:116424.
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2020	Albiol L, Büttner A, Pflanz D, Mikolajewicz N, Birkhold AI, Kramer I, Kneissel M, Duda GN, Checa S, Willie BM. Effects of long-term sclerostin deficiency on trabecular bone mass and adaption to limb loading differ in male and female mice. Calcif Tiss Int. April 2020;106(4):415-430.
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1999	Hildebrand T, Laib A, Müller R, Dequeker J, Rüegsegger P. Direct three-dimensional morphometric analysis of human cancellous bone: microstructural data from spine, femur, iliac crest, and calcaneus. J Bone Miner Res. July 1999;14(7):1167-1174.
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2002	Halloran BP, Ferguson VL, Simske SJ, Burghardt A, Venton LL, Majumdar S. Changes in bone structure and mass with advancing age in the male C57BL/6J mouse. J Bone Miner Res. June 2002;17(6):1044-1050.
2003	Komatsubara S, Mori S, Mashiba T, Ito M, Li J, Kaji Y, Akiyama T, Miyamoto K, Cao Y, Kawanishi J, Norimatsu H. Long‐term treatment of incadronate disodium accumulates microdamage but improves the trabecular bone microarchitecture in dog vertebra. J Bone Miner Res. March 2003;18(3):512-520.
2003	Amblard D, Lafage-Proust M-H, Laib A, Thomas T, Rüegsegger P, Alexandre C, Vico L. Tail suspension induces bone loss in skeletally mature mice in the C57BL/6J strain but not in the C3H/HeJ strain. J Bone Miner Res. March 2003;18(3):561-569.
2003	David V, Laroche N, Boudignon B, Lafage‐Proust M, Alexandre C, Ruegsegger P, Vico L. Noninvasive in vivo monitoring of bone architecture alterations in hindlimb‐unloaded female rats using novel three‐dimensional microcomputed tomography. J Bone Miner Res. September 2003;18(9):1622-1631.
2004	Judex S, Garman R, Squire M, Donahue L, Rubin C. Genetically based influences on the site‐specific regulation of trabecular and cortical bone morphology. J Bone Miner Res. April 2004;19(4):600-606.
2004	Judex S, Garman R, Squire M, Busa B, Donahue L-R, Rubin C. Genetically linked site-specificity of disuse osteoporosis. J Bone Miner Res. April 2004;19(4):607-613.
2004	Waarsing JH, Day JS, Weinans H. An improved segmentation method for in vivo μCT imaging. J Bone Miner Res. 2004;19(10):1640-1650.
2005	Bouxsein ML, Myers KS, Shultz KL, Donahue LR, Rosen CJ, Beamer WG. Ovariectomy‐induced bone loss varies among inbred strains of mice. J Bone Miner Res. July 2005;20(7):1085-1092.
2006	Stauber M, Rapillard L, van Lenthe GH, Zysset P, Müller R. Importance of individual rods and plates in the assessment of bone quality and their contribution to bone stiffness. J Bone Miner Res. April 2006;21(4):586-595.
2006	Hernandez CJ, Gupta A, Keaveny TM. A biomechanical analysis of the effects of resorption cavities on cancellous bone strength. J Bone Miner Res. August 2006;21(8):1248-1255.
2007	Eckstein F, Matsuura M, Kuhn V, Priemel M, Müller R, Link TM, Lochmüller E. Sex differences of human trabecular bone microstructure in aging are site‐dependent. J Bone Miner Res. June 2007;22(6):817-824.
2007	Glatt V, Canalis E, Stadmeyer L, Bouxsein ML. Age‐related changes in trabecular architecture differ in female and male C57BL/6J mice. J Bone Miner Res. August 2007;22(8):1197-1207.
2007	Badiei A, Bottema MJ, Fazzalari NL. Influence of orthogonal overload on human vertebral trabecular bone mechanical properties. J Bone Miner Res. 2007;22(11):1690-1699.
2008	Liu XS, Sajda P, Saha PK, Wehrli FW, Bevill G, Keaveny TM, Guo XE. Complete volumetric decomposition of individual trabecular plates and rods and its morphological correlations with anisotropic elastic moduli in human trabecular bone. J Bone Miner Res. February 2008;23(2):223-235.
2008	Arlot ME, Burt‐Pichat B, Roux J, Vashishth D, Bouxsein ML, Delmas PD. Microarchitecture influences microdamage accumulation in human vertebral trabecular bone. J Bone Miner Res. 2008;23(10):1613-1618.
2008	Buie HR, Moore CP, Boyd SK. Postpubertal architectural developmental patterns differ between the l3 vertebra and proximal tibia in three inbred strains of mice. J Bone Miner Res. 2008;23(12):2048-2059.
2010	Liu XS, Zhang XH, Sekhon KK, Adams MF, McMahon DJ, Bilezikian JP, Shane E, Guo XE. High-resolution peripheral quantitative computed tomography can assess microstructural and mechanical properties of human distal tibial bone. J Bone Miner Res. April 2010;25(4):746-756.
2010	Bouxsein ML, Boyd SK, Christiansen BA, Guldberg RE, Jepsen KJ, Müller R. Guidelines for assessment of bone microstructure in rodents using micro-computed tomography. J Bone Miner Res. July 2010;25(7):1468-1486.
2010	Liu XS, Cohen A, Shane E, Stein E, Rogers H, Kokolus SL, Yin PT, McMahon DJ, Lappe JM, Recker RR, Guo XE. Individual trabeculae segmentation (ITS)–based morphological analysis of high‐resolution peripheral quantitative computed tomography images detects abnormal trabecular plate and rod microarchitecture in premenopausal women with idiopathic osteoporosis. J Bone Miner Res. July 2010;25(7):1496-1505.
2010	Wegrzyn J, Roux J, Arlot ME, Boutroy S, Vilayphiou N, Guyen O, Delmas PD, Chapurlat R, Bouxsein ML. Role of trabecular microarchitecture and its heterogeneity parameters in the mechanical behavior of ex vivo human L3 vertebrae. J Bone Miner Res. November 2010;25(11):2324-2331.
2015	Maquer G, Musy SN, Wandel J, Gross T, Zysset PK. Bone volume fraction and fabric anisotropy are better determinants of trabecular bone stiffness than other morphological variables. J Bone Miner Res. June 2015;30(6):1000-1008.
2005	Boutroy S, Bouxsein ML, Munoz F, Delmas PD. In vivo assessment of trabecular bone microarchitecture by high-resolution peripheral quantitative computed tomography. J Clin Endocrinol Metab. December 2005;90(12):6508-6515.
2005	Thomsen JS, Laib A, Koller B, Prohaska S, Mosekilde L, Gowin W. Stereological measures of trabecular bone structure: comparison of 3D micro computed tomography with 2D histological sections in human proximal tibial bone biopsies. J Microsc (Oxford). 2005;218(2):171-179.
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2023	Ren Y, Zhang S, Weeks J, Moreno JR, He B, Xue T, Rainbolt J, Morita Y, Shu Y, Liu Y, Kates SL, Schwarz EM, Xie C. Reduced angiogenesis and delayed endochondral ossification in CD163^−/− mice highlights a role of M2 macrophages during bone fracture repair. J Orthop Res. November 2023;41(11):2384-2393.
2021	Ding M, Overgaard S. 3-D microarchitectural properties and rod- and plate-like trabecular morphometric properties of femur head cancellous bones in patients with rheumatoid arthritis, osteoarthritis, and osteoporosis. J Orthop Translat. May 2021;28:159-168.
2020	Bourzac C, Bensidhoum M, Manassero M, Chappard C, Michoux N, Pallu S, Portier H. Preventive moderate continuous running-exercise conditioning improves the healing of non-critical size bone defects in male Wistar rats: a pilot study using µCT. Life. December 2020;10(12):308.
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2002	Lane NE, Kumer JL, Majumdar S, Khan M, Lotz J, Stevens RE, Klein R, Phelps KV. The effects of synthetic conjugated estrogens, a (cenestin) on trabecular bone structure and strength in the ovariectomized rat model. Osteoporos Int. October 2002;13(10):816-823.
2005	Ito M, Nishida A, Aoyagi K, Uetani M, Hayashi K, Kawase M. Effects of risedronate on trabecular microstructure and biomechanical properties in ovariectomized rat tibia. Osteoporos Int. 2005;16(9):1042-1048.
2006	Stauber M, Müller R. Age-related changes in trabecular bone microstructures: global and local morphometry. Osteoporos Int. April 2006;17(4):616-626.
2008	Lochmüller E-M, Pöschl K, Würstlin L, Matsuura M, Müller R, Link TM, Eckstein F. Does thoracic or lumbar spine bone architecture predict vertebral failure strength more accurately than density? Osteoporos Int. April 2008;19(4):537-545.
2008	Campbell GM, Buie HR, Boyd SK. Signs of irreversible architectural changes occur early in the development of experimental osteoporosis as assessed by in vivo micro-CT. Osteoporos Int. October 2008;19(10):1409-1419.
2008	Chen H, Shoumura S, Emura S, Bunai Y. Regional variations of vertebral trabecular bone microstructure with age and gender. Osteoporos Int. October 2008;19(10):1473-1483.
2010	Chen H, Zhou X, Shoumura S, Emura S, Bunai Y. Age- and gender-dependent changes in three-dimensional microstructure of cortical and trabecular bone at the human femoral neck. Osteoporos Int. April 2010;21(4):627-636.
2013	Karim L, Tang SY, Sroga GE, Vashishth D. Differences in non-enzymatic glycation and collagen cross-links between human cortical and cancellous bone. Osteoporos Int. September 2013;24(9):2441-2447.
2015	Thomsen JS, Jensen MV, Niklassen AS, Ebbesen EN, Brüel A. Age-related changes in vertebral and iliac crest 3D bone microstructure: differences and similarities. Osteoporos Int. January 2015;26(1):219-228.
2020	Whittier DE, Boyd SK, Burghardt AJ, Paccou J, Ghasem-Zadeh A, Chapurlat R, Engelke K, Bouxsein ML. Guidelines for the assessment of bone density and microarchitecture in vivo using high-resolution peripheral quantitative computed tomography. Osteoporos Int. September 2020;31(9):1607-1627.
2006	Sierpowska J, Hakulinen MA, Töyräs J, Day JS, Weinans H, Kiviranta I, Jurvelin JS, Lappalainen R. Interrelationships between electrical properties and microstructure of human trabecular bone. Phys Med Biol. 2006;51(20):5289-5303.
2021	Felder AA, Monzem S, De Souza R, Javaheri B, Mills D, Boyde A, Doube M. The plate-to-rod transition in trabecular bone loss is elusive. R Soc Open Sci. June 9, 2021;8(5):201401.
2006	Gong H, Zhang M, Qin L, Lee KKH, Guo X, Shi S-Q. Regional variations in microstructural properties of vertebral trabeculae with structural groups. Spine. January 2006;31(1):24-32.
1998	Peyrin F, Salome M, Cloetens P, Laval-Jeantet AM, Ritman E, Rüegsegger P. Micro-ct examinations of trabecular bone samples at different resolutions: 14, 7 and 2 micron level. Technol Health Care. 1998;6(5-6):391-401.
2022	Bott KN. Effects of Exogenous Lipopolysaccharide Exposure on Bone Outcomes in Rodent Models [PhD thesis]. Brock University; 2022.
2013	Hussein Ali AI. 3-D Visualization and Prediction of Spine Fractures Under Axial Loading [PhD thesis]. Boston University; 2013.
2011	Cotter MM. Gross Morphology, Microarchitecture, Strength and Evolution of the Hominoid Vertebral Body [PhD thesis]. Cleveland, OH: Case Western Reserve University; May 2011.
2007	Liu XS. High-Resolution Image Based Micro-Mechanical Modeling of Trabecular Bone [PhD thesis]. Columbia University; 2007.
2010	Zhang XH. High Resolution Imaging Based Patient Specific Biomechanical Assessment of Bone Quality [PhD thesis]. New York, NY: Columbia University; 2010.
2015	Goff M. The Role of Micro and Ultra-Structure in Microdamage Accumulation in Cancellous Bone [PhD thesis]. Ithaca, NY: Cornell University; August 2015.
2017	Cresswell EN. Spatial Regulation of Bone Formation in Functional Adaptation of Cancellous Bone [PhD thesis]. Ithaca, NY: Cornell University; May 2017.
2018	Hunt HB. Characterization of Material Properties, Microarchitecture, and Mechanics of Bone from Subjects With Type 2 Diabetes Mellitus [PhD thesis]. Ithaca, NY: Cornell University; December 2018.
2018	Torres AM. Fatigue Behavior of Cancellous Bone, Microdamage Accumulation, and Biologically Inspired Cellular Solids [PhD thesis]. Ithaca, NY: Cornell University; August 2018.
2004	İnceoğlu S. Failure of Pedicle Screw-Bone Interface: Biomechanics of Pedicle Screw Insertion and Pullout [PhD thesis]. Cleveland State University; December 2004.
2004	Samuel SP. Fluid/solid Interactions in Cancellous Bone [PhD thesis]. Cleveland State University; August 2004.
2007	Boyd LM. Effects of a Genetic Mutation in Type IX Collagen on Morphology and Metabolism in a Murine Model of Intervertebral Disc Degeneration [PhD thesis]. Duke University; 2007.
2009	Christensen SE. The Role of Collagen VI in the Structure and Properties of the Knee Joint [PhD thesis]. Duke University; 2009.
2011	Donaldson FE. On Incorporating Bone Microstructure in Macro-Finite-Element Models [PhD thesis]. Edinburgh, UK: University of Edinburgh; March 2011.
2005	Day JS. Bone Quality: The Mechanical Effects of Microarchitecture and Matrix Properties [PhD thesis]. Erasmus University Rotterdam; 2005.
1999	Laib A. Microarchitecture of the Human Radius Assessed With High Resolution in Vivo 3D-QCT [PhD thesis]. Swiss Federal Institute of Technology Zürich; 1999.
2005	Stauber M. Volumetric Spatial Decomposition of Porous Microstructures: A Framework for Element Based Analysis of Trabecular Bone [PhD thesis]. Swiss Federal Institute of Technology Zürich; 2005.
2007	Kohler T. A Service-Oriented Platform for Visualization and High-Throughput Structural Characterization in Bone Phenomics [PhD thesis]. Swiss Federal Institute of Technology Zürich; 2007.
2008	Nazarian A. Relative Interaction of Material and Structure in Normal and Pathologic Bone [PhD thesis]. Swiss Federal Institute of Technology Zürich; 2008.
2008	Webster DJ. A Combined Experimental and Computational Model for Genetic Control of Micro Structural Bone Adaptation [PhD thesis]. Swiss Federal Institute of Technology Zürich; 2008.
2010	Müller T. Bioimaging and Biomechanics of Bone Competence and Implant Stability [PhD thesis]. Swiss Federal Institute of Technology Zürich; 2010.
2022	Goff E. Osteocyte Lacunar Biomarkers in Human Rare Bone Diseases [PhD thesis]. Swiss Federal Institute of Technology Zürich; 2022.
2014	Thote T. Evaluation of Therapeutics Strategies for Osteoarthritis Using Contrast Based CT Imaging Atlanta, GA: Georgia Institute of Technology; August 2014.
2002	Follet H. Caractérisation Biomécanique Et Modélisation 3D Par Imagerie X Et IRM Haute Résolution De L’os Spongieux Humain: Evaluation Du Risque Fracturaire [PhD thesis]. Institut national des sciences appliquées de Lyon (INSA Lyon); 2002.
2020	Lamarche BA. Morphometric Changes With Age in Human Trabecular Bone Structural Units (BSU) of the Lumbar Spine [Master's thesis]. Sudbury, ON: Laurentian University; 2020.
2014	Jameson JR. Characterization of Bone Material Properties and Microstructure in Osteogenesis Imperfecta/brittle Bone Disease [PhD thesis]. Marquette University; December 2014.
2014	Ellman R. Skeletal Adaptation to Reduced Mechanical Loading [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; September 2014.
2021	Fawcett EB. Effect of Brachial Plexus Birth Injury on Postnatal Glenohumeral Bone and Muscle [PhD thesis]. North Carolina State University; 2021.
2010	Shi X. Effects of Architecture on Microdamage Susceptibility in Trabecular Bone [PhD thesis]. University of Notre Dame; April 2010.
2011	Garrison JG. The Relative Importance of Stress State, Microarchitecture, and Damage Burden in the Failure Behavior of Trabecular Bone [PhD thesis]. University of Notre Dame; April 2011.
2013	Gaddini GW. Effects of 12 Months of Voluntary Alcohol Self-Administration on Intracortical Bone Remodeling in a Rhesus Macaque Model [Master's thesis]. Oregon State University; 2013.
2009	Bower AL. An Investigation of Trabecular Bone Morphology [PhD thesis]. State College, PA: Pennsylvania State University; December 2009.
2016	Hammond MA. The Influence of Collagen Crosslinking and Treadmill Exercise on the Mechanics, Composition, and Morphology of Bone At Multiple Length Scales [PhD thesis]. Purdue University; May 2016.
2011	Ahmed F. Multiscale Quantitative Imaging of Human Femoral Heads Using X-Ray Microtomography [PhD thesis]. Queen Mary University of London; 2011.
2013	Morton JJ. An Investigation of Rat Vertebra Failure Behaviour Under Uniaxial Compression Through Time-Lapsed Micro-CT Imaging [Master's thesis]. Queen's University; 2013.
2001	Tanck EJM. Mechanical Regulation of Bone Development [PhD thesis]. Nijmegen, Netherlands: Katholieke Universiteit Nijmegen; June 2001.
2007	Tang SY-C. Effects of Non-Enzymatic Glycation on the Biomechanical Behavior of Bone [PhD thesis]. Troy, NY: Rensselaer Polytechnic Institute; 2007.
2009	Alwood JS. Radiation and Mechanical Unloading Effects on Mouse Vertebral Bone: Ground-Based Models of the Spaceflight Environment [PhD thesis]. Stanford University; September 2009.
2004	Mittra ES. Assessment of Trabecular Bone Quality Using Microstructure, Micro-Mechanics and Micro-Finite Element Modeling [PhD thesis]. Stony Brook, NY: Stony Brook University; May 2004.
2005	Chung S. Bone Image Analysis: Quantifying Topological Change in Bone Under Uniform Erosion [PhD thesis]. Stony Brook, NY: Stony Brook University; December 2005.
2013	Christen P. Deciphering the Secret Message Within Bone Microstructure [PhD thesis]. Eindhoven University of Technology; 2013.
2009	Varga P. Prediction of Distal Radius Fracture Load Using HR-PQCT-Based Finite Element Analysis [PhD thesis]. Vienna University of Technology; December 2009.
2012	Dall'Ara E. QCT Based Finite Element Models of the Human Vertebra and Femur: Validation With Experiments and Comparison With Bone Densitometry [PhD thesis]. Vienna University of Technology; October 2012.
2018	Bachmann S. Age, Sex and Treatment Related Changes of Bone Mineral Density Based on Ct Data [Master's thesis]. Vienna University of Technology; October 2018.
2014	Colombo A. La micro-architecture de l’os trabéculaire en croissance: Variabilité tridimensionnelle normale et pathologique analysée par microtomodensitométrie [PhD thesis]. Université de Bordeaux; December 15, 2014.
2001	Boyd SK. Microstructural Bone Adaptation in an Experimental Model of Osteoarthritis [PhD thesis]. Calgary, AB: University of Calgary; January 2001.
2005	Cooper DML. 3D Micro-CT Imaging of Human Cortical Bone Porosity: A Novel Method for Estimating Age At Death [PhD thesis]. Calgary, AB: University of Calgary; December 2005.
2007	Klinck RJ. Establishing in Vivo Micro-CT for Use in Mouse Models of Osteoprosis [Master's thesis]. Calgary, AB: University of Calgary; December 2007.
2007	MacNeil JAM. Clinical Assessment of Bone Quality [PhD thesis]. Calgary, AB: University of Calgary; June 2007.
2010	Manske SL. Muscle Disuse and Vibration Effects on Bone Morphology [PhD thesis]. Calgary, AB: University of Calgary; December 2010.
2012	Nishiyama KKS. In Vivo Assessment of Bone Microarchitecture and Estimated Bone Strength [PhD thesis]. Calgary, AB: University of Calgary; October 2012.
2012	Pauchard Y. In Vivo Monitoring of Longitudinal Changes in Bone Micro-Architecture Using High-Resolution Peripheral Computed Tomography [PhD thesis]. Calgary, AB: University of Calgary; February 2012.
2013	Owoc JS. Large Scale Elasto-Plastic Modelling for in Vivo Assessment of Bone Strength from High Resolution Peripheral Quantitative Computed Tomography [Master's thesis]. Calgary, AB: University of Calgary; August 2013.
2021	Besler BAA. Bone as an Orientable, Smooth Surface: Distance Transforms, Morphometry, and Adaptation [PhD thesis]. Calgary, AB: University of Calgary; August 2021.
2022	Mielczarek CB. An Investigation of Local Microarchitecture Topology Changes in Long-Duration Spaceflight [Master's thesis]. Calgary, AB: University of Calgary; November 2022.
2002	Morgan EF-i. The Dependence on Anatomic Site of Trabecular Bone Structure-Function Relationships [PhD thesis]. Berkeley, CA: Berkeley, University of California; 2002.
2003	Bayraktar HH. Multiaxial Strength and Micromechanics of Human Bone [PhD thesis]. Berkeley, CA: Berkeley, University of California; 2003.
2008	Bevill GR. Micromechanical Modeling of Failure in Trabecular Bone [PhD thesis]. Berkeley, CA: Berkeley, University of California; 2008.
2013	Sanyal A. Bone Strength Multi-Axial Behavior: Volume Fraction, Anisotropy and Microarchitecture [PhD thesis]. Berkeley, CA: Berkeley, University of California; 2013.
2013	Soicher MA. Fabrication and Characterization of Remineralized Bone Matrices (RBM) for Use as Bone Tissue Engineering Substrates [PhD thesis]. Davis, University of California; 2013.
2013	Wang Y-K. Multi-Level Micromechanical Modeling of Bone Tissues [PhD thesis]. Los Angeles, CA: Los Angeles, University of California; 2013.
2010	Rodriguez AG. Human Endplate Permeability and Microstructure and Their Relationship to Disc Degeneration [PhD thesis]. San Francisco, University of California; 2010.
2018	Hilton K. The Effect of Boundary Conditions and Architecture on the Response of Cancellous Bone [Master's thesis]. Cape Town, South Africa: University of Cape Town; October 18, 2018.
2016	Chen C. Mechanical and Micro-Structural Modeling of Trabecular Bone by in Vivo Imaging [PhD thesis]. University of Iowa; December 2016.
2022	Zhang X. Development of an Image-Based System for Assessment of Bone Density, Geometry, and Micro-Architecture Suitable for Human Studies [PhD thesis]. University of Iowa; August 2022.
2007	Ruffoni D. Modeling of Material and Architectural Quality of Trabecular Bone [PhD thesis]. Liège, Belgique: Université de Liège; September 2007.
2017	de Bakker CMJ. Structural Adaptations of the Maternal Skeleton in Response to Reproduction and Lactation [PhD thesis]. Philadelphia, PA: University of Pennsylvania; 2017.
2013	Pratt I. In Vivo Imaging of Cortical Porosity by Synchrotron Phase Contrast Micro Computed Tomography [Master's thesis]. University of Saskatchewan; August 2013.
2022	Sales EdS. The Spatio-Temporal Behavior of Basic Multicellular Units in a PTH-Induced Cortical Bone Remodeling Rabbit Model [Master's thesis]. University of Saskatchewan; August 2022.
2016	Andronowski JM. Evaluating Differential Nuclear DNA Yield Rates Among Human Bone Tissue Types: A Synchrotron Micro-CT Approach [PhD thesis]. Knoxville, University of Tennessee; May 2016.
2013	Liu CC. Effects of a New Conjugate Drug in a Rat Model of Postmenopausal Osteoporosis [Master's thesis]. University of Toronto; 2013.
2018	Zhang L. Effects of Osteoblast-Specific Gα_S Overexpression on Skeletal Development and Response to Catabolic and Anabolic Stimuli Using a Transgenic Mouse Model [PhD thesis]. University of Toronto; 2018.
2013	Mecke D. Probabilistic Analysis of the Microstructure of Human Trabecular Bone With High and Low Volume Fractions [Master's thesis]. San Antionio, TX: University of Texas at San Antonio; December 2013.
2017	Kirby ML. Digital Modeling of Trabecular Bones: Structural Analysis and Probabilistic Modeling Techniques [Master's thesis]. San Antionio, TX: University of Texas at San Antonio; August 2017.

Year	Entry
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1987	Lorensen WE, Cline HE. Marching cubes: a high resolution 3D surface construction algorithm. Comput Graph. 1987;21(4):163-169.
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1976	Dalén N, Hellström L-G, Jacobson B. Bone mineral content and mechanical strength of the femoral neck. Acta Orthop Scand. 1976;47(5):503-508.
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1983	Parfitt AM, Mathews CH, Villanueva AR, Kleerekoper M, Frame B, Rao DS. Relationships between surface, volume, and thickness of iliac trabecular bone in aging and in osteoporosis: implications for the microanatomic and cellular mechanisms of bone loss. J Clin Invest. October 1983;72(4):1396-1409.
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