2002 |
Müller R. The Zürich experience: one decade of three-dimensional high-resolution computed tomography. Top Magn Reson Imaging. 2002;13(5):307-322. |
9 |
6 |
2021 |
Callens SJP, Tourolle né Betts DC, Müller R, Zadpoor AA. The local and global geometry of trabecular bone. Acta Biomater. August 2021;130:343-361. |
0 |
0 |
2001 |
Fajardo RJ, Müller R. Three‐dimensional analysis of nonhuman primate trabecular architecture using micro‐computed tomography. Am J Phys Anthropol. 2001;115(4):327-336. |
27 |
26 |
2003 |
Judex S, Boyd S, Qin Y-X, Turner S, Ye K, Müller R, Rubin C. Adaptations of trabecular bone to low magnitude vibrations result in more uniform stress and strain under load. Ann Biomed Eng. January 2003;31(1):12-20. |
26 |
12 |
2006 |
Boyd SK, Moser S, Kuhn M, Klinck RJ, Krauze PL, Müller R, Gasser JA. Evaluation of three-dimensional image registration methodologies for in vivo micro-computed tomography. Ann Biomed Eng. October 2006;34(10):1587-1599. |
27 |
13 |
2012 |
Webster D, Wirth A, van Lenthe GH, Müller R. Experimental and finite element analysis of the mouse caudal vertebrae loading model: prediction of cortical and trabecular bone adaptation. Biomech Model Mechanobiol. January 2012;11(1-2):221-230. |
10 |
9 |
2012 |
Christen P, van Rietbergen B, Lambers FM, Müller R, Ito K. Bone morphology allows estimation of loading history in a murine model of bone adaptation. Biomech Model Mechanobiol. March 2012;11(3-4):483-492. |
10 |
4 |
1996 |
Müller R, Hahn M, Vogel M, Delling G, Rüegsegger P. Morphometric analysis of noninvasively assessed bone biopsies: comparison of high-resolution computed tomography and histologic sections. Bone. March 1996;18(3):215-220. |
44 |
39 |
1998 |
Müller R, Van Campenhout H, Van Damme B, Van der Perre G, Dequeker J, Hildebrand T, Rüegsegger P. Morphometric analysis of human bone biopsies: a quantitative structural comparison of histological sections and micro-computed tomography. Bone. July 1998;23(1):59-66. |
87 |
65 |
2005 |
Shefelbine SJ, Simon U, Claes L, Gold A, Gabet Y, Bab I, Müller R, Augat P. Prediction of fracture callus mechanical properties using micro-CT images and voxel-based finite element analysis. Bone. March 2005;36(3):480-488. |
27 |
26 |
2006 |
Stauber M, Müller R. Volumetric spatial decomposition of trabecular bone into rods and plates: a new method for local bone morphometry. Bone. 2006;38(4):475-484. |
56 |
45 |
2006 |
Thurner PJ, Wyss P, Voide R, Stauber M, Stampanoni M, Sennhauser U, Müller R. Time-lapsed investigation of three-dimensional failure and damage accumulation in trabecular bone using synchrotron light. Bone. August 2006;39(2):289-299. |
60 |
50 |
2006 |
Boyd SK, Davison P, Müller R, Gasser JA. Monitoring individual morphological changes over time in ovariectomized rats by in vivo micro-computed tomography. Bone. October 2006;39(4):854-862. |
30 |
23 |
2006 |
van Lenthe GH, Stauber M, Müller R. Specimen-specific beam models for fast and accurate prediction of human trabecular bone mechanical properties. Bone. December 2006;39(6):1182-1189. |
19 |
17 |
2006 |
Nazarian A, Stauber M, Zurakowski D, Snyder BD, Müller R. The interaction of microstructure and volume fraction in predicting failure in cancellous bone. Bone. December 2006;39(6):1196-1202. |
49 |
44 |
2008 |
Nazarian A, Snyder BD, Zurakowski D, Müller R. Quantitative micro-computed tomography: a non-invasive method to assess equivalent bone mineral density. Bone. August 2008;43(2):302-311. |
22 |
18 |
2008 |
van Lenthe GH, Voide R, Boyd SK, Müller R. Tissue modulus calculated from beam theory is biased by bone size and geometry: implications for the use of three-point bending tests to determine bone tissue modulus. Bone. October 2008;43(4):717-723. |
21 |
16 |
2009 |
Mueller TL, Stauber M, Kohler T, Eckstein F, Müller R, van Lenthe GH. Non-invasive bone competence analysis by high-resolution pQCT: an in vitro reproducibility study on structural and mechanical properties at the human radius. Bone. February 2009;44(2):364-371. |
35 |
26 |
2009 |
Voide R, Schneider P, Stauber M, Wyss P, Stampanoni M, Sennhauser U, van Lenthe GH, Müller R. Time-lapsed assessment of microcrack initiation and propagation in murine cortical bone at submicrometer resolution. Bone. August 2009;45(2):164-173. |
39 |
32 |
2009 |
Mueller TL, van Lenthe GH, Stauber M, Gratzke C, Eckstein F, Müller R. Regional, age and gender differences in architectural measures of bone quality and their correlation to bone mechanical competence in the human radius of an elderly population. Bone. November 2009;45(5):882-891. |
21 |
19 |
2010 |
Rubin MR, Dempster DW, Kohler T, Stauber M, Zhou H, Shane E, Nickolas T, Stein E, Sliney J Jr, Silverberg SJ, Bilezikian JP, Müller R. Three dimensional cancellous bone structure in hypoparathyroidism. Bone. January 2010;46(1):190-195. |
9 |
7 |
2010 |
Schneider P, Meier M, Wepf R, Müller R. Towards quantitative 3d imaging of the osteocyte lacuno-canalicular network. Bone. November 2010;47(5):848-858. |
30 |
27 |
2011 |
Schulte FA, Lambers FM, Kuhn G, Müller R. In vivo micro-computed tomography allows direct three-dimensional quantification of both bone formation and bone resorption parameters using time-lapsed imaging. Bone. March 2011;48(3):433-442. |
34 |
22 |
2011 |
Mueller TL, Christen D, Sandercott S, Boyd SK, van Rietbergen B, Eckstein F, Lochmüller E-M, Müller R, van Lenthe GH. Computational finite element bone mechanics accurately predicts mechanical competence in the human radius of an elderly population. Bone. June 1, 2011;48(6):1232-1238. |
44 |
29 |
2011 |
Schneider P, Meier M, Wepf R, Müller R. Serial FIB/SEM imaging for quantitative 3D assessment of the osteocyte lacuno-canalicular network. Bone. August 2011;49(2):304-311. |
28 |
25 |
2011 |
Voide R, Schneider P, Stauber M, van Lenthe GH, Stampanoni M, Müller R. The importance of murine cortical bone microstructure for microcrack initiation and propagation. Bone. December 2011;49(6):1186-1193. |
14 |
8 |
2011 |
Lambers FM, Schulte FA, Kuhn G, Webster DJ, Müller R. Mouse tail vertebrae adapt to cyclic mechanical loading by increasing bone formation rate and decreasing bone resorption rate as shown by time-lapsed in vivo imaging of dynamic bone morphometry. Bone. December 2011;49(6):1340-1350. |
22 |
17 |
2014 |
Carriero A, Doube M, Vogt M, Busse B, Zustin J, Levchuk A, Schneider P, Müller R, Shefelbine SJ. Altered lacunar and vascular porosity in osteogenesis imperfecta mouse bone as revealed by synchrotron tomography contributes to bone fragility. Bone. April 2014;61:116-124. |
15 |
9 |
2021 |
Zhang J, Wang Y, Cheng K-l, Cheuk K, Lam T-p, Hung ALH, Cheng JCY, Qiu Y, Müller R, Christen P, Lee WYW. Association of higher bone turnover with risk of curve progression in adolescent idiopathic scoliosis. Bone. February 2021;143:115655. |
1 |
0 |
2021 |
Besler BA, Schadow JE, Durongbhan P, Steiner TH, Choo RJ, Zulliger MA, Wilke M, Atal K, Firminger C, Quintin A, Koller B, Müller R, Nesic D, Stok KS. Quantitative measures of bone shape, cartilage morphometry and joint alignment are associated with disease in an ACLT and MMx rat model of osteoarthritis. Bone. May 2021;146:115903. |
3 |
1 |
2021 |
Ohs N, Collins CJ, Tourolle DC, Atkins PR, Schroeder BJ, Blauth M, Christen P, Müller R. Automated segmentation of fractured distal radii by 3D geodesic active contouring of in vivo HR-pQCT images. Bone. June 2021;147:115930. |
0 |
0 |
2022 |
Goff E, Cohen A, Shane E, Recker RR, Kuhn G, Müller R. Large-scale osteocyte lacunar morphological analysis of transiliac bone in normal and osteoporotic premenopausal women. Bone. July 1, 2022;160:116424. |
1 |
0 |
2023 |
Yang KG, Goff E, Cheng K-l, Kuhn GA, Wang Y, Cheng JC-y, Qiu Y, Müller R, Lee WY-w. Abnormal morphological features of osteocyte lacunae in adolescent idiopathic scoliosis: a large-scale assessment by ultra-high-resolution micro-computed tomography. Bone. January 2023;166:116594. |
0 |
0 |
2023 |
Walle M, Eggemann D, Atkins PR, Kendall JJ, Stock K, Müller R, Collins CJ. Motion grading of high-resolution quantitative computed tomography supported by deep convolutional neural networks. Bone. January 2023;166:116607. |
2 |
0 |
2023 |
Walle M, Whittier DE, Schenk D, Atkins PR, Blauth M, Zysset P, Lippuner K, Müller R, Collins CJ. Precision of bone mechanoregulation assessment in humans using longitudinal high-resolution peripheral quantitative computed tomography in vivo. Bone. July 2023;172:116780. |
1 |
0 |
2023 |
Whittier DE, Walle M, Schenk D, Atkins PR, Collins CJ, Zysset P, Lippuner K, Müller R. A multi-stack registration technique to improve measurement accuracy and precision across longitudinal HR-pQCT scans. Bone. November 2023;176:116893. |
0 |
0 |
1996 |
Rüegsegger P, Koller B, Müller R. A microtomographic system for the nondestructive evaluation of bone architecture. Calcif Tiss Int. 1996;58(1):24-29. |
185 |
122 |
2004 |
Nägele E, Kuhn V, Vogt H, Link TM, Müller R, Lochmüller E-M, Eckstein F. Technical considerations for microstructural analysis of human trabecular bone from specimens excised from various skeletal sites. Calcif Tiss Int. 2004;75(1):15-22. |
10 |
7 |
2008 |
Nazarian A, von Stechow D, Zurakowski D, Müller R, Snyder BD. Bone volume fraction explains the variation in strength and stiffness of cancellous bone affected by metastatic cancer and osteoporosis. Calcif Tiss Int. December 2008;83(6):368-379. |
40 |
38 |
2008 |
Verhulp E, Van Rietbergen B, Müller R, Huiskes R. Micro-finite element simulation of trabecular-bone post-yield behaviour: effects of material model, element size and type. Comput Methods Biomech Biomed Eng. August 2008;11(4):389-395. |
46 |
42 |
2008 |
Webster DJ, Morley PL, van Lenthe GH, Müller R. A novel in vivo mouse model for mechanically stimulated bone adaptation: a combined experimental and computational validation study. Comput Methods Biomech Biomed Eng. October 2008;11(5):435-441. |
26 |
15 |
2003 |
Judex S, Boyd S, Qin Y-X, Miller L, Müller R, Rubin C. Combining high-resolution micro-computed tomography with material composition to define the quality of bone tissue. Curr Osteoporos Rep. June 2003;1(1):11-19. |
31 |
16 |
2018 |
Levchuk A, Schneider P, Meier M, Vogel P, Donaldson F, Müller R. An automated step-wise micro-compression device for 3D dynamic image-guided failure assessment of bone tissue on a microstructural level using time-lapsed tomography. Front Mater. June 2018;5:32. |
3 |
2 |
2008 |
Arbenz P, van Lenthe GH, Mennel U, Müller R, Sala M. A scalable multi‐level preconditioner for matrix‐free µ‐finite element analysis of human bone structures. Int J Num Meth Eng. February 12, 2008;73(7):927-947. |
26 |
16 |
1999 |
Van Rietbergen B, Müller R, Ulrich D, Rüegsegger P, Huiskes R. Tissue stresses and strain in trabeculae of a canine proximal femur can be quantified from computer reconstructions. J Biomech. February 1999;32(2):165-173. |
57 |
38 |
2004 |
Nazarian A, Müller R. Time-lapsed microstructural imaging of bone failure behavior. J Biomech. 2004;37(1):55-65. |
81 |
60 |
2004 |
Kotha SP, Hsieh Y-F, Strigel RM, Müller R, Silva MJ. Experimental and finite element analysis of the rat ulnar loading model: correlations between strain and bone formation following fatigue loading. J Biomech. April 2004;37(4):541-548. |
34 |
27 |
2006 |
Boyd SK, Müller R. Smooth surface meshing for automated finite element model generation from 3D image data. J Biomech. 2006;39(7):1287-1295. |
19 |
15 |
2007 |
Nazarian A, Muller J, Zurakowski D, Müller R, Snyder BD. Densitometric, morphometric and mechanical distributions in the human proximal femur. J Biomech. 2007;40(11):2573-2579. |
19 |
17 |
2008 |
Verhulp E, van Rietbergen B, Müller R, Huiskes R. Indirect determination of trabecular bone effective tissue failure properties using micro-finite element simulations. J Biomech. 2008;41(7):1479-1485. |
50 |
44 |
2008 |
Nazarian A, Bauernschmitt M, Eberle C, Meier D, Müller R, Snyder BD. Design and validation of a testing system to assess torsional cancellous bone failure in conjunction with time-lapsed micro-computed tomographic imaging. J Biomech. December 5, 2008;41(16):3496-3501. |
5 |
5 |
2010 |
Cory E, Nazarian A, Entezari V, Vartanians V, Müller R, Snyder BD. Compressive axial mechanical properties of rat bone as functions of bone volume fraction, apparent density and micro-CT based mineral density. J Biomech. March 22, 2010;43(5):953-960. |
16 |
14 |
2012 |
Wirth AJ, Müller R, van Lenthe GH. The discrete nature of trabecular bone microarchitecture affects implant stability. J Biomech. April 5, 2012;45(6):1060-1067. |
9 |
9 |
1996 |
Merz B, Niederer P, Müller R, Rüegsegger P. Automated finite element analysis of excised human femora based on precision-QCT. J Biomech Eng. August 1996;118(3):387-390. |
21 |
20 |
2007 |
Kim CH, Zhang H, Mikhail G, von Stechow D, Müller R, Kim HS, Guo XE. Effects of thresholding techniques on μCT-based finite element models of trabecular bone. J Biomech Eng. 2007;129(4):481-486. |
12 |
10 |
2005 |
Nazarian A, Stauber M, Müller R. Design and implementation of a novel mechanical testing system for cellular solids. J Biomed Mater Res. 2005;B73(2):400-411. |
18 |
8 |
1996 |
Müller R, Hildebrand T, Häuselmann HJ, Rüegsegger P. In vivo reproducibility of three‐dimensional structural properties of noninvasive bone biopsies using 3D‐pQCT. J Bone Miner Res. November 1996;11(11):1745-1750. |
32 |
22 |
1999 |
Hildebrand T, Laib A, Müller R, Dequeker J, Rüegsegger P. Direct three-dimensional morphometric analysis of human cancellous bone: microstructural data from spine, femur, iliac crest, and calcaneus. J Bone Miner Res. July 1999;14(7):1167-1174. |
274 |
219 |
2000 |
Turner CH, Hsieh Y, Müller R, Bouxsein ML, Baylink DJ, Rosen CJ, Grynpas MD, Donahue LR, Beamer WG. Genetic regulation of cortical and trabecular bone strength and microstructure in inbred strains of mice. J Bone Miner Res. June 2000;15(6):1126-1131. |
57 |
35 |
2001 |
Turner CH, Hsieh Y, Müller R, Bouxsein ML, Rosen CJ, McCrann ME, Donahue LR, Beamer WG. Variation in bone biomechanical properties, microstructure, and density in BXH recombinant inbred mice. J Bone Miner Res. February 2001;16(2):206-213. |
24 |
14 |
2001 |
Dempster DW, Cosman F, Kurland ES, Zhou H, Nieves J, Woelfert L, Shane E, Plavetić K, Müller R, Bilezikian J, Lindsay R. Effects of daily treatment with parathyroid hormone on bone microarchitecture and turnover in patients with osteoporosis: a paired biopsy study. J Bone Miner Res. October 2001;16(10):1846-1853. |
53 |
33 |
2001 |
Nicholson PHF, Müller R, Cheng XG, Rüegsegger P, Van Der Perre G, Dequeker J, Boonen S. Quantitative ultrasound and trabecular architecture in the human calcaneus. J Bone Miner Res. October 2001;16(10):1886-1892. |
4 |
4 |
2002 |
Eckstein F, Lochmüller E-M, Lill CA, Kuhn V, Schneider E, Delling G, Müller R. Bone strength at clinically relevant sites displays substantial heterogeneity and is best predicted from site-specific bone densitometry. J Bone Miner Res. January 2002;17(1):162-171. |
20 |
17 |
2002 |
Rubin C, Turner AS, Müller R, Mittra E, McLeod K, Lin W, Qin Y. Quantity and quality of trabecular bone in the femur are enhanced by a strongly anabolic, noninvasive mechanical intervention. J Bone Miner Res. February 2002;17(2):349-357. |
57 |
37 |
2002 |
Boyd SK, Müller R, Zernicke RF. Mechanical and architectural bone adaptation in early stage experimental osteoarthritis. J Bone Miner Res. April 2002;17(4):687-694. |
35 |
4 |
2003 |
Kim CH, Takai E, Zhou H, Von Stechow D, Müller R, Dempster DW, Guo XE. Trabecular bone response to mechanical and parathyroid hormone stimulation: the role of mechanical microenvironment. J Bone Miner Res. December 2003;18(12):2116-2125. |
34 |
28 |
2006 |
Stauber M, Rapillard L, van Lenthe GH, Zysset P, Müller R. Importance of individual rods and plates in the assessment of bone quality and their contribution to bone stiffness. J Bone Miner Res. April 2006;21(4):586-595. |
36 |
29 |
2007 |
Eckstein F, Matsuura M, Kuhn V, Priemel M, Müller R, Link TM, Lochmüller E. Sex differences of human trabecular bone microstructure in aging are site‐dependent. J Bone Miner Res. June 2007;22(6):817-824. |
30 |
26 |
2007 |
Melton LJ, Riggs BL, van Lenthe GH, Achenbach SJ, Müller R, Bouxsein ML, Amin S, Atkinson EJ, Khosla S. Contribution of in vivo structural measurements and load/strength ratios to the determination of forearm fracture risk in postmenopausal women. J Bone Miner Res. September 2007;22(9):1442-1448. |
59 |
45 |
2007 |
Schneider P, Stauber M, Voide R, Stampanoni M, Donahue LR, Müller R. Ultrastructural properties in cortical bone vary greatly in two inbred strains of mice as assessed by synchrotron light based micro‐ and nano‐CT. J Bone Miner Res. October 2007;22(10):1557-1570. |
47 |
32 |
2009 |
Kirmani S, Christen D, van Lenthe GH, Fischer PR, Bouxsein ML, McCready LK, Melton LJ III, Riggs BL, Amin S, Müller R, Khosla S. Bone structure at the distal radius during adolescent growth. J Bone Miner Res. June 2009;24(6):1033-1042. |
34 |
29 |
2010 |
Bouxsein ML, Boyd SK, Christiansen BA, Guldberg RE, Jepsen KJ, Müller R. Guidelines for assessment of bone microstructure in rodents using micro-computed tomography. J Bone Miner Res. July 2010;25(7):1468-1486. |
386 |
341 |
2013 |
Christen D, Melton LJ III, Zwahlen A, Amin S, Khosla S, Müller R. Improved fracture risk assessment based on nonlinear micro-finite element simulations from HRpQCT images at the distal radius. J Bone Miner Res. December 2013;28(12):2601-2608. |
19 |
19 |
2020 |
Kiel DP, Kemp JP, Rivadeneira F, Westendorf JJ, Karasik D, Duncan EL, Imai Y, Müller R, Flannick J, Bonewald L, Burtt N. The musculoskeletal knowledge portal: making omics data useful to the broader scientific community. J Bone Miner Res. September 2020;35(9):1626-1633. |
4 |
2 |
2012 |
Christen D, Levchuk A, Schori S, Schneider P, Boyd SK, Müller R. Deformable image registration and 3D strain mapping for the quantitative assessment of cortical bone microdamage. J Mech Behav Biomed Mater. April 2012;8:184-193. |
25 |
22 |
2013 |
Carretta R, Luisier B, Bernoulli D, Stüssi E, Müller R, Lorenzetti S. Novel method to analyze post-yield mechanical properties at trabecular bone tissue level. J Mech Behav Biomed Mater. 2013;20:6-18. |
16 |
14 |
2013 |
Carretta R, Stüssi E, Müller R, Lorenzetti S. Within subject heterogeneity in tissue-level post-yield mechanical and material properties in human trabecular bone. J Mech Behav Biomed Mater. August 2013;24:64-73. |
21 |
20 |
2016 |
Georgiadis M, Müller R, Schneider P. Techniques to assess bone ultrastructure organization: orientation and arrangement of mineralized collagen fibrils. J R Soc Interface. June 1, 2016;13(119):20160088. |
28 |
25 |
1995 |
Müller R, Rüegsegger P. Three-dimensional finite element modelling of non-invasively assessed trabecular bone structures. Med Eng Phys. March 1995;17(2):126-133. |
40 |
28 |
2011 |
Lorenzetti S, Carretta R, Müller R, Stüssi E. A new device and method for measuring the elastic modulus of single trabeculae. Med Eng Phys. October 2011;33(8):993-1000. |
11 |
8 |
2006 |
Stauber M, Müller R. Age-related changes in trabecular bone microstructures: global and local morphometry. Osteoporos Int. April 2006;17(4):616-626. |
33 |
30 |
2008 |
Lochmüller E-M, Pöschl K, Würstlin L, Matsuura M, Müller R, Link TM, Eckstein F. Does thoracic or lumbar spine bone architecture predict vertebral failure strength more accurately than density? Osteoporos Int. April 2008;19(4):537-545. |
3 |
2 |
2010 |
Melton LJ III, Christen D, Riggs BL, Achenbach SJ, Müller R, van Lenthe GH, Amin S, Atkinson EJ, Khosla S. Assessing forearm fracture risk in postmenopausal women. Osteoporos Int. July 2010;21(7):1161-1169. |
23 |
18 |
1994 |
Müller R, Hildebrand T, Rüegsegger P. Non-invasive bone biopsy: a new method to analyse and display the three-dimensional structure of trabecular bone. Phys Med Biol. January 1994;39(1):145-164. |
80 |
44 |
2013 |
Schulte FA, Ruffoni D, Lambers FM, Christen D, Webster DJ, Kuhn G, Müller R. Local mechanical stimuli regulate bone formation and resorption in mice at the tissue level. PLoS One. April 2013;8(4):e62172. |
28 |
20 |
2016 |
Georgiadis M, Guizar-Sicairos M, Gschwend O, Hangartner P, Bunk O, Müller R, Schneider P. Ultrastructure organization of human trabeculae assessed by 3D sSAXS and relation to bone microarchitecture. PLoS One. August 22, 2016;11(8):e0159838. |
6 |
6 |
2020 |
Scheuren AC, Kuhn GA, Müller R. Effects of long-term in vivo micro-CT imaging on hallmarks of osteopenia and frailty in aging mice. PLoS One. September 23, 2020;15(9):e0239534. |
0 |
0 |
2021 |
Malhotra A, Walle M, Paul GR, Kuhn GA, Müller R. Application of subject-specific adaptive mechanical loading for bone healing in a mouse tail vertebral defect. Sci Rep. January 22, 2021;11:1861. |
1 |
0 |
1997 |
Ulrich D, Hildebrand T, Van Rietbergen B, Müller R, Rüegsegger P. The quality of trabecular bone evaluated with micro-computed tomography, FEA and mechanical testing. Stud Health Technol Inform. 1997;40:97-112. |
53 |
40 |
1996 |
Müller R, Koller B, Hildebrand T, Laib A, Gianolini S, Rüegsegger P. Resolution dependency of microstructural properties of cancellous bone based on three-dimensional μ-tomography. Technol Health Care. April 1996;4(1):113-119. |
43 |
31 |
1998 |
Müller R, Gerber SC, Hayes WC. Micro-compression: a novel technique for the nondestructive assessment of local bone failure. Technol Health Care. December 1998;6(5-6):433-444. |
67 |
50 |