| 2011 |
Dragomir-Daescu D, Op Den Buijs J, McEligot S, Dai Y, Entwistle RC, Salas C, Melton LJ III, Bennet KE, Khosla S, Amin S. Robust QCT/FEA models of proximal femur stiffness and fracture load during a sideways fall on the hip. Ann Biomed Eng. February 2011;39(2):742-755. |
44 |
41 |
| 2016 |
Farr JN, Khosla S. Determinants of bone strength and quality in diabetes mellitus in humans. Bone. January 2016;82:28-34. |
20 |
19 |
| 2020 |
Aquino-Martinez R, Rowsey JL, Fraser DG, Eckhardt BA, Khosla S, Farr JN, Monroe DG. LPS-induced premature osteocyte senescence: implications in inflammatory alveolar bone loss and periodontal disease pathogenesis. Bone. March 2020;132:115220. |
0 |
0 |
| 2020 |
Robinson JW, Blixt NC, Norton A, Mansky KC, Ye Z, Aparicio C, Wagner BM, Benton AM, Warren GL, Khosla S, Gaddy D, Suva LJ, Potter LR. Male mice with elevated C-type natriuretic peptide-dependent guanylyl cyclase-B activity have increased osteoblasts, bone mass and bone strength. Bone. June 2020;135:115320. |
0 |
0 |
| 2020 |
Keyak JH, Kaneko TS, Khosla S, Amin S, Atkinson EJ, Lang TF, Sibonga JD. Hip load capacity and yield load in men and women of all ages. Bone. August 2020;137:115321. |
0 |
0 |
| 2016 |
Diez-Perez A, Bouxsein M, Eriksen E, Khosla S, Nyman J, Papapoulos S, Tang S. Technical note: recommendations for a standard procedure to assess cortical bone at the tissue-level in vivo using impact microindentation. Bone Rep. December 2016;5:181-185. |
15 |
5 |
| 2002 |
Riggs BL, Khosla S, Melton LJ III. Sex steroids and the construction and conservation of the adult skeleton. Endocr Rev. June 2002;23(3):279-302. |
62 |
58 |
| 2021 |
Shiraishi K, Burghardt AJ, Osaki M, Khosla S, Carballido-Gamio J. Global and spatial compartmental interrelationships of bone density, microstructure, geometry and biomechanics in the distal radius in a Colles’ fracture study using HR-pQCT. Front Endocrinol (Lausanne). May 26, 2021;12:568454. |
0 |
0 |
| 2019 |
Zebaze R, Atkinson EJ, Peng Y, Bui M, Ghasem‐Zadeh A, Khosla S, Seeman E. Increased cortical porosity and reduced trabecular density are not necessarily synonymous with bone loss and microstructural deterioration. JMBR Plus. July 2019;3(4):e10078. |
6 |
4 |
| 1997 |
Melton LJ III, Khosla S, Atkinson EJ, O'Fallon WM, Riggs BL. Relationship of bone turnover to bone density and fractures. J Bone Miner Res. July 1997;12(7):1083-1091. |
21 |
19 |
| 1998 |
Riggs BL, Khosla S, Melton LJ III. A unitary model for involutional osteoporosis: estrogen deficiency causes both type I and type II osteoporosis in postmenopausal women and contributes to bone loss in aging men. J Bone Miner Res. May 1998;13(5):763-773. |
43 |
39 |
| 2004 |
Riggs BL, Melton LJ III, Robb RA, Camp JJ, Atkinson EJ, Peterson JM, Rouleau PA, McCollough CH, Bouxsein ML, Khosla S. Population-based study of age and sex differences in bone volumetricdensity, size, geometry, and structure at different skeletal sites. J Bone Miner Res. December 2004;19(12):1945-1954. |
107 |
89 |
| 2006 |
Khosla S, Riggs BL, Atkinson EJ, Oberg AL, McDaniel LJ, Holets M, .Peterson JM, Melton LJ III. Effects of sex and age on bone microstructure at the ultradistal radius: a population-based noninvasive in vivo assessment. J Bone Miner Res. January 2006;21(1):124-131. |
112 |
105 |
| 2006 |
Riggs BL, Melton LJ III, Robb RA, Camp JJ, Atkinson EJ, Oberg AL, Rouleau PA, McCollough CH, Khosla S, Bouxsein ML. Population-based analysis of the relationship of whole bone strength indices and fall-related loads to age- and sex-specific patterns of hip and wrist fractures. J Bone Miner Res. February 2006;21(2):315-323. |
24 |
14 |
| 2006 |
Bouxsein ML, Melton LJ III, Riggs BL, Muller J, Atkinson EJ, Oberg AL, Robb RA, Camp JJ, Rouleau PA, McCollough CH, Khosla S. Age‐ and sex‐specific differences in the factor of risk for vertebral fracture: a population‐based study using QCT. J Bone Miner Res. September 2006;21(9):1475-1482. |
28 |
17 |
| 2007 |
Melton LJ, Riggs BL, van Lenthe GH, Achenbach SJ, Müller R, Bouxsein ML, Amin S, Atkinson EJ, Khosla S. Contribution of in vivo structural measurements and load/strength ratios to the determination of forearm fracture risk in postmenopausal women. J Bone Miner Res. September 2007;22(9):1442-1448. |
59 |
45 |
| 2007 |
Khosla S, Burr D, Cauley J, Dempster DW, Ebeling PR, Felsenberg D, Gagel RF, Gilsanz V, Guise T, Koka S, McCauley LK, McGowan J, McKee MD, Mohla S, Pendrys DG, Raisz LG, Ruggiero SL, Shafer DM, Shum L, Silverman SL, Van Poznak CH, Watts N, Woo S-B, Shane E. Bisphosphonate-associated osteonecrosis of the jaw: report of a task force of the American Society for Bone and Mineral Research. J Bone Miner Res. October 2007;22(10):1479-1491. |
31 |
22 |
| 2007 |
Melton LJ III, Riggs BL, Keaveny TM, Achenbach SJ, Hoffmann PF, Camp JJ, Rouleau PA, Bouxsein ML, Amin S, Atkinson EJ, Robb RA, Khosla S. Structural determinants of vertebral fracture risk. J Bone Miner Res. December 2007;22(12):1885-1892. |
51 |
27 |
| 2008 |
Riggs BL, Melton LJ, Robb RA, Camp JJ, Atkinson EJ, McDaniel L, Amin S, Rouleau PA, Khosla S. A population‐based assessment of rates of bone loss at multiple skeletal sites: evidence for substantial trabecular bone loss in young adult women and men. J Bone Miner Res. February 2008;23(2):205-214. |
40 |
39 |
| 2009 |
Kirmani S, Christen D, van Lenthe GH, Fischer PR, Bouxsein ML, McCready LK, Melton LJ III, Riggs BL, Amin S, Müller R, Khosla S. Bone structure at the distal radius during adolescent growth. J Bone Miner Res. June 2009;24(6):1033-1042. |
34 |
29 |
| 2010 |
Keaveny TM, Kopperdahl DL, Melton LJ III, Hoffmann PF, Amin S, Riggs BL, Khosla S. Age‐dependence of femoral strength in white women and men. J Bone Miner Res. May 2010;25(5):994-1001. |
30 |
20 |
| 2011 |
Amin S, Kopperdhal DL, Melton LJ, Achenbach SJ, Therneau TM, Riggs BL, Keaveny TM, Khosla S. Association of hip strength estimates by finite‐element analysis with fractures in women and men. J Bone Miner Res. July 2011;26(7):1593-1600. |
19 |
14 |
| 2011 |
Khosla S, Bellido TM, Drezner MK, Gordon CM, Harris TB, Kiel DP, Kream BE, LeBoff MS, Lian JB, Peterson CA, Rosen CJ, Williams JP, Winer KK, Sherman SS. Forum on aging and skeletal health: summary of the proceedings of an ASBMR workshop. J Bone Miner Res. November 2011;26(11):2565-2578. |
1 |
1 |
| 2013 |
Christen D, Melton LJ III, Zwahlen A, Amin S, Khosla S, Müller R. Improved fracture risk assessment based on nonlinear micro-finite element simulations from HRpQCT images at the distal radius. J Bone Miner Res. December 2013;28(12):2601-2608. |
19 |
19 |
| 2014 |
Farr JN, Drake MT, Amin S, Melton LJ III, McCready LK, Khosla S. In vivo assessment of bone quality in postmenopausal women with type 2 diabetes. J Bone Miner Res. April 2014;29(4):787-795. |
45 |
42 |
| 2014 |
Bala Y, Zebaze R, Ghasem-Zadeh A, Atkinson EJ, Iuliano S, Peterson JM, Amin S, Bjørnerem Å, Melton LJ III, Johansson H, Kanis JA, Khosla S, Seeman E. Cortical porosity identifies women with osteopenia at increased risk for forearm fractures. J Bone Miner Res. June 2014;29(6):1356-1362. |
30 |
23 |
| 2016 |
Khosla S, Shane E. A crisis in the treatment of osteoporosis. J Bone Miner Res. August 2016;31(8):1485-1487. |
29 |
24 |
| 2017 |
Khosla S, Cauley JA, Compston J, Kiel DP, Rosen C, Saag KG, Shane E. Addressing the crisis in the treatment of osteoporosis: a path forward. J Bone Miner Res. March 2017;32(3):424-430. |
16 |
13 |
| 2019 |
Clarke BL, Khosla S. Is it time to stop (or pause) vertebral augmentation? J Bone Miner Res. January 2019;34(1):1-2. |
0 |
0 |
| 2020 |
Conley RB, Adib G, Adler RA, Åkesson KE, Alexander IM, Amenta KC, Blank RD, Brox WT, Carmody EE, Chapman‐Novakofski K, Clarke BL, Cody KM, Cooper C, Crandall CJ, Dirschl DR, Eagen TJ, Elderkin AL, Fujita M, Greenspan SL, Halbout P, Hochberg MC, Javaid M, Jeray KJ, Kearns AE, King T, Koinis TF, Koontz JS, Kužma M, Lindsey C, Lorentzon M, Lyritis GP, Michaud LB, Miciano A, Morin SN, Mujahid N, Napoli N, Olenginski TP, Puzas JE, Rizou S, Rosen CJ, Saag K, Thompson E, Tosi LL, Tracer H, Khosla S, Kiel DP. Secondary fracture prevention: consensus clinical recommendations from a multistakeholder coalition. J Bone Miner Res. January 2020;35(1):36-52. |
12 |
9 |
| 2020 |
Chandra A, Lagnado AB, Farr JN, Monroe DG, Park S, Hachfeld C, Tchkonia T, Kirkland JL, Khosla S, Passos JF, Pignolo RJ. Targeted reduction of senescent cell burden alleviates focal radiotherapy‐related bone loss. J Bone Miner Res. June 2020;35(6):1119-1131. |
1 |
0 |
| 2020 |
Hong N, Lee DC, Khosla S, Keaveny TM, Rhee Y. Comparison of vertebral and femoral strength between white and asian adults using finite element analysis of computed tomography scans. J Bone Miner Res. December 2020;35(12):2345-2354. |
0 |
0 |
| 2021 |
Eastell R, Black DM, Lui L, Chines A, Marin F, Khosla S, de Papp AE, Cauley JA, Mitlak B, McCulloch CE, Vittinghoff E, Bauer DC; Foundation for the National Institutes of Health (FNIH) Bone Quality Project. Treatment‐related changes in bone turnover and fracture risk reduction in clinical trials of antiresorptive drugs: proportion of treatment effect explained. J Bone Miner Res. February 2021;36(2):236-243. |
0 |
0 |
| 2022 |
Eastell R, Vittinghoff E, Lui L-Y, McCulloch CE, Pavo I, Chines A, Khosla S, Cauley JA, Mitlak B, Bauer DC, Bouxsein M, Black DM. Validation of the surrogate threshold effect for change in bone mineral density as a surrogate endpoint for fracture outcomes: the FNIH-ASBMR SABRE project. J Bone Miner Res. January 2022;37(1):29-35. |
5 |
3 |
| 2022 |
Whittier DE, Samelson EJ, Hannan MT, Burt LA, Hanley DA, Biver E, Szulc P, Sornay-Rendu E, Merle B, Chapurlat R, Lespessailles E, Wong AKO, Goltzman D, Khosla S, Ferrari S, Bouxsein ML, Kiel DP, Boyd SK. Bone microarchitecture phenotypes identified in older adults are associated with different levels of osteoporotic fracture risk. J Bone Miner Res. March 2022;37(3):428-439. |
6 |
3 |
| 2022 |
Chandra A, Lagnado AB, Farr JN, Schleusner M, Monroe DG, Saul D, Passos JF, Khosla S, Pignolo RJ. Bone marrow adiposity in models of radiation- and aging-related bone loss is dependent on cellular senescence. J Bone Miner Res. May 2022;37(5):997-1011. |
0 |
0 |
| 2022 |
Doolittle ML, Saul D, Kaur J, Rowsey JL, Eckhardt B, Vos S, Grain S, Kroupova K, Ruan M, Weivoda M, Oursler MJ, Farr JN, Monroe DG, Khosla S. Skeletal effects of inducible ERα deletion in osteocytes in adult mice. J Bone Miner Res. September 2022;37(9):1750-1760. |
0 |
0 |
| 2023 |
Whittier DE, Samelson EJ, Hannan MT, Burt LA, Hanley DA, Biver E, Szulc P, Sornay-Rendu E, Merle B, Chapurlat R, Lespessailles E, Wong AKO, Goltzman D, Khosla S, Ferrari S, Bouxsein ML, Kiel DP, Boyd SK. A fracture risk assessment tool for high resolution peripheral quantitative computed tomography. J Bone Miner Res. September 2023;38(9):1234-1244. |
1 |
1 |
| 2023 |
Bartenschlager S, Cavallaro A, Pogarell T, Chaudry O, Uder M, Khosla S, Schett G, Engelke K. Opportunistic screening with CT: comparison of phantomless BMD calibration methods. J Bone Miner Res. November 2023;38(11):1689-1699. |
0 |
0 |
| 2020 |
Eckhardt BA, Rowsey JL, Thicke BS, Fraser DG, O’Grady KL, Bondar OP, Hines JM, Singh RJ, Thoreson AR, Rakshit K, Lagnado AB, Passos JF, Vella A, Matveyenko AV, Khosla S, Monroe DG, Farr JN. Accelerated osteocyte senescence and skeletal fragility in mice with type 2 diabetes. JCI Insight. May 7, 2020;5(9):135236. |
2 |
2 |
| 2015 |
Zysset P, Qin L, Lang T, Khosla S, Leslie WD, Shepherd JA, Schousboe JT, Engelke K. Clinical use of quantitative computed tomography–based finite element analysis of the hip and spine in the management of osteoporosis in adults: the 2015 ISCD official positions—part II. J Clin Densitom. July–September 2015;18(3):359-392. |
18 |
16 |
| 1998 |
Khosla S, Melton LJ III, Atkinson EJ, O’Fallon WM, Klee GG, Riggs BL. Relationship of serum sex steroid levels and bone turnover markers with bone mineral density in men and women: a key role for bioavailable estrogen. J Clin Endocrinol Metab. July 1998;83(7):2266-2274. |
20 |
16 |
| 2008 |
Melton LJ III, Riggs BL, Leibson CL, Achenbach SJ, Camp JJ, Bouxsein ML, Atkinson EJ, Robb RA, Khosla S. A bone structural basis for fracture risk in diabetes. J Clin Endocrinol Metab. December 2008;03(12):4804-4809. |
15 |
14 |
| 2003 |
Eghbali-Fatourechi G, Khosla S, Sanyal A, Boyle WJ, Lacey DL, Riggs BL. Role of RANK ligand in mediating increased bone resorption in early postmenopausal women. J Clin Invest. April 2003;111(8):1221-1230. |
26 |
23 |
| 2011 |
Rachner TD, Khosla S, Hofbauer LC. Osteoporosis: now and the future. Lancet. April 9, 2011;377(9773):1276-1287. |
35 |
35 |
| 2017 |
Khosla S, Hofbauer LC. Osteoporosis treatment: recent developments and ongoing challenges. Lancet Diabetes Endocrinol. November 2017;5(11):898-907. |
26 |
26 |
| 2019 |
Samelson EJ, Broe KE, Xu H, Yang L, Boyd S, Biver E, Szulc P, Adachi J, Amin S, Atkinson E, Berger C, Burt L, Chapurlat R, Chevalley T, Ferrari S, Goltzman D, Hanley DA, Hannan MT, Khosla S, Liu C-T, Lorentzon M, Mellstrom D, Merle B, Nethander M, Rizzoli R, Sornay-Rendu E, Van Rietbergen B, Sundh D, Wong AKO, Ohlsson C, Demissie S, Kiel DP, Bouxsein ML. Cortical and trabecular bone microarchitecture as an independent predictor of incident fracture risk in older women and men in the Bone Microarchitecture International Consortium (BoMIC): a prospective study. Lancet Diabetes Endocrinol. January 2019;7(1):34-43. |
63 |
33 |
| 2008 |
Drake MT, Clarke BL, Khosla S. Bisphosphonates: mechanism of action and role in clinical practice. Mayo Clin Proc. September 2008;83(9):1032-1045. |
40 |
40 |
| 2010 |
Melton LJ III, Christen D, Riggs BL, Achenbach SJ, Müller R, van Lenthe GH, Amin S, Atkinson EJ, Khosla S. Assessing forearm fracture risk in postmenopausal women. Osteoporos Int. July 2010;21(7):1161-1169. |
23 |
18 |
| 2017 |
Bonaretti S, Majumdar S, Lang TF, Khosla S, Burghardt AJ. The comparability of HR-pQCT bone measurements is improved by scanning anatomically standardized regions. Osteoporos Int. July 2017;28(7):2115-2128. |
22 |
18 |
| 2020 |
Keaveny TM, Clarke BL, Cosman F, Orwoll ES, Siris ES, Khosla S, Bouxsein ML. Biomechanical computed tomography analysis (BCT) for clinical assessment of osteoporosis. Osteoporos Int. June 2020;31(6):1025-1048. |
13 |
8 |