Cell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitment

McBeath, Rowena<sup>1</sup>; Pirone, Dana M.<sup>2</sup>; Nelson, Celeste M.<sup>2</sup>; Bhadriraju, Kiran<sup>2</sup>; Chen, Christopher S.<sup>1,2,3</sup>

Year	Entry
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2009	Guilak F, Cohen DM, Estes BT, Gimble JM, Liedtke W, Chen CS. Control of stem cell fate by physical interactions with the extracellular matrix. Cell Stem Cell. July 2, 2009;5(1):17-26.
2007	David V, Martin A, Lafage-Proust M-H, Malaval L, Peyroche S, Jones DB, Vico L, Guignandon A. Mechanical loading down-regulates peroxisome proliferator-activated receptor γ in bone marrow stromal cells and favors osteoblastogenesis at the expense of adipogenesis. Endocrinology. May 2007;148(5):2553-2562.
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2007	Malone AMD. Mechanotransduction Mechanisms in Bone Cells [PhD thesis]. Stanford University; August 2007.
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2012	Uzer G. Role of Fluid Shear Modulation on Bone Cell Metabolism During High-Frequency Oscillatory Vibrations [PhD thesis]. Stony Brook, NY: Stony Brook University; December 2012.
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2018	Patel VS. Harnessing Cell Mechanosensitivity to Combat Obesity-Induced Systemic Metabolic Disruptions and to Promote Protein Production for Bioprocessing [PhD thesis]. Stony Brook, NY: Stony Brook University; December 2018.
2015	Tseng L-F. Shape Memory Electrospun Scaffolds for Cell Mechanobiology and Bone Regenerative Applications [PhD thesis]. University of Syracuse; December 2015.
2016	Wang J. Studies of Cell Motility and Differentiation in Complex 3D in Vitro Microenvironment [PhD thesis]. University of Syracuse; December 2016.
2020	Hoang PK. Cardiac Organoid Technology and Computational Processing of Cardiac Physiology for Advanced Drug Screening Applications [PhD thesis]. University of Syracuse; December 2020.
2017	Gonzalez Fernandez T. Integrating Non-Viral Gene Therapy and 3D Bioprinting for Bone, Cartilage and Osteochondral Tissue Engineering [PhD thesis]. Trinity College Dublin; December 2017.
2017	Irvine AD. Modulating Mechanical Cues and Oxygen Availability to Regulate Chondrogenesis Within MSC Laden Hydrogels [PhD thesis]. Trinity College Dublin; June 2017.
2018	Olvera Ramos DP. Spatial Presentation of Tissue Specific Extracellular Matrix Components and Growth Factors on Porous Electrospun Fibre Scaffolds for Bone-Ligament Interface Tissue Engineering [PhD thesis]. Trinity College Dublin; 2018.
2013	Pineda Fortin ET. The Role of the Cytoskeleton in Pluripotent Stem Cell Differentiation [PhD thesis]. Tulane University; 2013.
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2012	Kohen N. Designing Synthetic Culture Systems for Human Stem Cell Culture [PhD thesis]. Berkeley, CA: Berkeley, University of California; 2012.
2014	Rode NA. Design of Electrospun Hydrogel Fibers Containing Multivalent Peptide Conjugates for Cardiac Tissue Engineering [PhD thesis]. Berkeley, CA: Berkeley, University of California; 2014.
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2021	McDonough RC. Controlled Calcium Activation Via Chemogenetic Signaling Platforms for Tissue Engineering of Articular Cartilage [PhD thesis]. University of Delaware; 2021.
2013	Yew AG. Clinorotation Time-Lapse Microscopy for Live-Cell Assays in Simulated Microgravity [PhD thesis]. University of Maryland; 2013.
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2009	Krizan SJ. The Role of Adhesion Strength in Human Mesenchymal Stem Cell Osteoblastic Differentiation on Biodegradable Polymers [PhD thesis]. University of Michigan; 2009.
2023	Madsen E. Cell and Material Specific Dual-Functional Peptides for Enhancing Mesenchymal Stem Cell Migration for Bone Tissue Engineering [PhD thesis]. University of Michigan; 2023.
2022	Blank MA. Defining Mechanisms by Which EphrinB2 in Osteocytes Controls Bone Strength and Material Quality [PhD thesis]. University of Melbourne; September 2022.
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2021	Speer JE. Engineering Nucleus Pulposus Cell-Matrix Interactions With Laminin Ligands for Tissue Regeneration [PhD thesis]. St. Louis, MO: Washington University in St. Louis; May 2021.

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