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Parfitt, A. M.
1
Bone remodeling: relationship to the amount and structure of bone, and the pathogenesis and prevention of fractures
Osteoporosis: Etiology, Diagnosis, and Management
Affiliations
1
Bone and Mineral Research Laboratory, Department of Medicine,
Henry Ford Hospital
, Detroit, Michigan 48202
Cited Works (43)
Year
Entry
1965
Atkinson PJ. Changes in resorption spaces in femoral cortical bone with age.
J Pathol Bacteriol
. January 1965;89(1):173-178.
1985
Cann CE, Genant HK, Kolb FO, Ettinger B. Quantitative computed tomography for prediction of vertebral fracture risk.
Bone
. 1985;6(1):1-7.
1980
Cann CE, Genant HK. Precise measurement of vertebral mineral content using computed tomography.
J Comput Assist Tomogr
. 1980;4(4):493-500.
1979
Parfitt AM. Quantum concept of bone remodeling and turnover: implications for the pathogenesis of osteoporosis.
Calcif Tiss Int
. 1979;28(1):1-5.
1982
Riggs BL, Wahner HW, Seeman E, Offord KP, Dunn WL, Mazess RB, Johnson KA, Melton LJ III. Changes in bone mineral density of the proximal femur and spine with aging: differences between the postmenopausal and senile osteoporosis syndromes.
J Clin Invest
. October 1982;70(4):716-723.
1984
Parfitt AM. The cellular basis of bone remodeling: the quantum concept reexamined in light of recent advances in the cell biology of bone.
Calcif Tiss Int
. March 1984;36(suppl 1):S37-S45.
1983
Kragstrup J, Melsen F. Three-dimensional morphology of trabecular bone osteons reconstructed from serial sections.
Metab Bone Dis Rel Res
. 1983–1984;5(3):127-130.
1966
Arnold JS, Bartley MH, Tont SA, Jenkins DP. Skeletal changes in aging and disease.
Clin Orthop Relat Res
. December 1966;49:17-38.
1986
Riggs BL, Wahner HW, Melton LJ III, Richelson LS, Judd HL, Offord KP. Rates of bone loss in the appendicular and axial skeletons of women: evidence of substantial vertebral bone loss before menopause.
J Clin Invest
. May 1986;77(5):1487-1491.
1979
Lakes R, Saha S. Cement line motion in bone.
Science
. May 4, 1979;204(4392):501-503.
1978
Singh I. The architecture of cancellous bone.
J Anat
. October 1978;127(2):305-310.
1967
Dunnill MS, Anderson JA, Whitehead R. Quantitative histological studies on age changes in bone.
J Pathol Bacteriol
. October 1967;94(2):275-291.
1977
Tappen NC. Three‐dimensional studies of resorption spaces and developing osteons.
Am J Anat
. July 1977;149(3):301-331.
1985
Kleerekoper M, Villanueva AR, Stanciu J, Rao DS, Parfitt AM. The role of three-dimensional trabecular microstructure in the pathogenesis of vertebral compression fractures.
Calcif Tiss Int
. 1985;37(6):594-597.
1981
Darby AJ, Meunier PJ. Mean wall thickness and formation periods of trabecular bone packets in idiopathic osteoporosis.
Calcif Tiss Int
. December 1981;33(3):199-204.
1982
Genant HK, Cann CE, Ettinger B, Gordan GS. Quantitative computed tomography of vertebral spongiosa: a sensitive method for detecting early bone loss after oophorectomy.
Ann Intern Med
. 1982;97(5):699-705.
1971
Meunier P, Aaron J, Edouard C, Vignon G. Osteoporosis and the replacement of cell populations of the marrow by adipose tissue: a quantitative study of 84 iliac bone biopsies.
Clin Orthop Relat Res
. October 1971;80:147-154.
1972
Martin RB. The effects of geometric feedback in the development of osteoporosis.
J Biomech
. September 1972;5(5):447-455.
1960
Frost HM. Micropetrosis.
J Bone Joint Surg
. January 1960;42A(1):144-150.
1977
Whitehouse WJ. Cancellous bone in the anterior part of the iliac crest.
Calcif Tiss Res
. December 1977;23(1):67-76.
1969
Wakamatsu E, Sissons HA. The cancellous bone of the iliac crest.
Calcif Tiss Res
. December 1969;4(1):147-161.
1984
Lanyon LE. Functional strain as a determinant for bone remodeling.
Calcif Tiss Int
. March 1984;36(suppl 1):S56-S61.
1980
Martin RB, Pickett JC, Zinaich S. Studies of skeletal remodeling in aging men.
Clin Orthop Relat Res
. June 1980;149:268-282.
1985
Frost HM. The pathomechanics of osteoporoses.
Clin Orthop Relat Res
. November 1985;200:198-225.
1972
Jaworski ZF, Meunier P, Frost HM. Observations on two types of resorption cavities in human lamellar cortical bone.
Clin Orthop Relat Res
. March–April 1972;83:279-285.
1982
Mazess RB. On aging bone loss.
Clin Orthop Relat Res
. May 1982;165:239-252.
1983
Parfitt AM, Mathews CH, Villanueva AR, Kleerekoper M, Frame B, Rao DS. Relationships between surface, volume, and thickness of iliac trabecular bone in aging and in osteoporosis: implications for the microanatomic and cellular mechanisms of bone loss.
J Clin Invest
. October 1983;72(4):1396-1409.
1982
Parfitt AM. The coupling of bone formation to bone resorption: a critical analysis of the concept and of its relevance to the pathogenesis of osteoporosis.
Metab Bone Dis Rel Res
. 1982;4(1):1-6.
1984
Keshawarz NM, Recker RR. Expansion of the medullary cavity at the expense of cortex in postmenopausal osteoporosis.
Metab Bone Dis Rel Res
. 1984;5(5):223-228.
1964
Currey JD. Some effects of ageing in human haversian systems.
J Anat
. January 1964;98(1):69-75.
1974
Minaire P, Meunier P, Edouard C, Bernard J, Courpron P, Bourret J. Quantitative histological data on disuse osteoporosis: comparison with biological data.
Calcif Tiss Res
. December 1974;17(1):57-73.
1983
Parfitt AM. The physiologic and clinical significance of bone histomorphometric data. In: Recker RR, ed.
Bone Histomorphometry: Techniques and Interpretation
. Boca Raton, FL: Inc., CRC Press; 1983:143-223.
1983
Jaworski ZFG, Kimmel DB, Jee WSS. Cell kinetics underlying skeltal growth and bone tissue turnover. In: Recker RR, ed.
Bone Histomorphometry: Techniques and Interpretation
. Boca Raton, FL: Inc., CRC Press; 1983:225-239.
1980
Jaworski ZFG, Liskova-Kiar M, Uhthoff HK. Effect of long-term immobilisation on the pattern of bone loss in older dogs.
J Bone Joint Surg
. February 1980;62B(1):104-110.
1982
Martin RB, Burr DB. A hypothetical mechanism for the stimulation of osteonal remodelling by fatigue damage.
J Biomech
. 1982;15(3):137-139.
1984
Carter DR. Mechanical loading histories and cortical bone remodeling.
Calcif Tiss Int
. March 1984;36(suppl 1):S19-S24.
1965
Hattner R, Epker BN, Frost HM. Suggested sequential mode of control of changes in cell behaviour in adult bone remodelling.
Nature
. May 1, 1965;206(4983):489-490.
1984
Eriksen EF, Melsen F, Mosekilde L. Reconstruction of the resorptive site in iliac trabecular bone: a kinetic model for bone resorption in 20 normal individuals.
Metab Bone Dis Rel Res
. 1984;5(5):235-242.
1985
Cummings SR, Kelsey JL, Nevitt MC, O'Dowd KJ. Epidemiology of osteoporosis and osteoporotic fractures.
Epidemiol Rev
. 1985;7:178-208.
1978
Lips P, Courpron P, Meunier PJ. Mean wall thickness of trabecular bone packets in the human iliac crest: changes with age.
Calcif Tiss Res
. 1978;26(1):13-17.
1986
Dempster DW, Shane E, Horbert W, Lindsay R. A simple method for correlative light and scanning electron microscopy of human iliac crest bone biopsies: qualitative observations in normal and osteoporotic subjects.
J Bone Miner Res
. February 1986;1(1):15-21.
1966
Jowsey J. Studies of Haversian systems in man and some animals.
J Anat
. October 1966;100(4):857-864.
1982
Krølner B, Pors Nielsen S. Bone mineral content of the lumbar spine in normal and osteoporotic women: cross-sectional and longitudinal studies.
Clin Sci
(London). March 1982;62(3):329-336.
Cited By (34)
Year
Entry
1990
Parfitt AM. Bone-forming cells in clinical conditions. In: Hall BK, ed.
Bone. Volume 1: The Osteoblast and Osteocyte
. Caldwell, NJ: Inc., The Telford Press; 1990:351-429.
2002
Banse X. When density fails to predict bone strength.
Acta Orthop Scand
. 2002;73(2)(suppl 303):2-57.
1990
Melton LJ III, Eddy DM, Johnston C Jr. Screening for osteoporosis.
Ann Intern Med
. April 1, 1990;112(7):516-528.
1996
Amling M, Pösl M, Ritzel H, Hahn M, Vogel M, Wening VJ, Delling G. Architecture and distribution of cancellous bone yield vertebral fracture clues: a histomorphometric analysis of the complete spinal column from 40 autopsy specimens.
Arch Orthop Trauma Surg
. July 1996;115(5):262-269.
1991
Parfitt AM, Foldes J. The ambiguity of interstitial bone thickness: a new approach to the mechanism of trabecular thinning.
Bone
. 1991;12(2):119-122.
1992
Parfitt AM. Implications of architecture for the pathogenesis and prevention of vertebral fracture.
Bone
. 1992;13(suppl 2):S41-S47.
1993
Parfitt AM. Morphometry of bone resorption: introduction and overview.
Bone
. ;14(3):435-441.
1993
Brockstedt H, Kassem M, Eriksen EF, Mosekilde L, Melsen F. Age- and sex-related changes in iliac cortical bone mass and remodeling.
Bone
. July–August 1993;14(4):681-691.
1994
Schaffler MB, Pitchford WC, Choi K, Riddle JM. Examination of compact bone microdamage using back-scattered electron microscopy.
Bone
. September–October 1994;15(5):483-488.
1995
Dempster DW, Birchman R, Xu R, Lindsay R, Shen V. Temporal changes in cancellous bone structure of rats immediately after ovariectomy.
Bone
. January 1995;16(1):157-161.
1995
Boyce RW, Wronski TJ, Ebert DC, Stevens ML, Paddock CL, Youngs TA, Gundersen HJG. Direct stereological estimation of three-dimensional connectivity in rat vertebrae: effect of estrogen, etidronate and risedronate following ovariectomy.
Bone
. February 1995;16(2):209-213.
1995
Boyce RW, Ebert DC, Youngs TA, Paddock CL, Mosekilde L, Stevens ML, Gundersen HJG. Unbiased estimation of vertebral trabecular connectivity in calcium-restricted ovariectomized minipigs.
Bone
. June 1995;16(6):637-642.
1995
Schaffler MB, Choi K, Milgrom C. Aging and matrix microdamage accumulation in human compact bone.
Bone
. December 1995;17(6):521-525.
1996
Lin JH. Bisphosphonates: a review of their pharmacokinetic properties.
Bone
. February 1996;18(2):75-85.
1998
Wang XD, Masilamani NS, Mabrey JD, Alder ME, Agrawal CM. Changes in the fracture toughness of bone may not be reflected in its mineral density, porosity, and tensile properties.
Bone
. July 1998;23(1):67-72.
2020
Seeman E. Time present and time past are both perhaps present in time future, and time future contained in time past — TSEliot, The Four Quartets.
Bone
. August 2020;137:115427.
1992
Frost HM, Jee WSS. On the rat model of human osteopenias and osteoporoses.
Bone Miner
. September 1992;18(3):227-236.
1993
Forwood MR, Burr DB. Physical activity and bone mass: exercises in futility?
Bone Miner
. May 1993;21(2):89-112.
1998
Wohl GR, Loehrke L, Watkins BA, Zernicke RF. Effects of high-fat diet on mature bone mineral content, structure, and mechanical properties.
Calcif Tiss Int
. July 1998;63(1):74-79.
2000
Lee TC, O'Brien FJ, Taylor D. The nature of fatigue damage in bone.
Int J Fract
. November 2000;22(10):847-853.
1991
Foldes J, Parfitt AM, Shih MS, Rao DS, Kleerekoper M. Structural and geometric changes in iliac bone: relationship to normal aging and osteoporosis.
J Bone Miner Res
. July 1991;6(7):759-766.
1991
Cohen‐Solal ME, Shih M, Lundy MW, Parfitt AM. A new method for measuring cancellous bone erosion depth: application to the cellular mechanisms of bone loss in postmenopausal osteoporosis.
J Bone Miner Res
. December 1991;6(12):1331-1338.
1996
Amling M, Herden S, Pösl M, Hahn M, Ritzel H, Delling G. Heterogeneity of the skeleton: comparison of the trabecular microarchitecture of the spine, the iliac crest, the femur, and the calcaneus.
J Bone Miner Res
. January 1996;11(1):36-45.
1996
Han Z, Palnitkar S, Rao DS, Nelson D, Parfitt AM. Effect of ethnicity and age or menopause on the structure and geometry of iliac bone.
J Bone Miner Res
. December 1996;11(12):1967-1975.
1997
Han Z-H, Palnitkar S, Rao DS, Nelson D, Parfitt AM. Effects of ethnicity and age or menopause on the remodeling and turnover of iliac bone: implications for mechanisms of bone loss.
J Bone Miner Res
. April 1997;12(4):498-508.
1992
Riggs BL, Melton LJ III. The prevention and treatment of osteoporosis.
NEJM
. August 27, 1992;327(9):620-627.
1998
Mosekilde L. The effect of modelling and remodelling on human vertebral body architecture.
Technol Health Care
. December 1998;6(5-6):287-297.
2000
Mosekilde L. Age-related changes in bone mass, structure, and strength: effects of loading.
Z Rheumatol
. February 2000;59(suppl 1):I1-I9.
1994
Sims NA.
The Pathogenesis of Post-Menopausal Osteopaenia Using the Oophorectomised Rat Model
[PhD thesis]. Adelaide, Australia: The University of Adelaide; July 1994.
2011
Yao H.
Microstructure-Based Characterization and Modeling of Trabecular Bone Deformation and Failure
[PhD thesis]. Southern Methodist University; August 3, 2011.
2002
Wohl GR.
Bone Mechanics in Transplanted Osteochondral Grafts
[PhD thesis]. Calgary, AB: University of Calgary; September 2002.
2007
MacNeil JAM.
Clinical Assessment of Bone Quality
[PhD thesis]. Calgary, AB: University of Calgary; June 2007.
1993
McCubbrey DA.
The Macroscopic Architectural Properties of Vertebral Trabecular Bone and Their Relation to Whole Vertebral Failure Loads
[PhD thesis]. University of Michigan; 1993.
1993
Boyce TM.
Aging Changes Within the Human Femoral Neck Cortex
[PhD thesis]. University of Utah; August 1993.