Grodzinsky, Alan J.

Name	Count	Oldest	Newest
Massachusetts Institute of Technology	50	1974	2023

Name

Count

Oldest

Newest

Massachusetts Institute of Technology

1974

2023

Year	Article	Times Cited	Times Cited (no self-citations)
1990	Frank EH, Grodzinsky AJ, Phillips SL, Grimshaw PE. Physicochemical and bioelectrical determinants of cartilage material properties. In: Mow VC, Ratcliffe A, Woo SL-Y, eds. Biomechanics of Diarthrodial Joints. Vol 1. New York, NY: Springer-Verlag; 1990:261-282.	27	16
1988	Kim Y-J, Sah RLY, Doong J-YH, Grodzinsky AJ. Fluorometric assay of DNA in cartilage explants using Hoechst 33258. Anal Ciochem. October 1988;174(1):168-176.	141	84
2000	Grodzinsky AJ, Levenston ME, Jin M, Frank EH. Cartilage tissue remodeling in response to mechanical forces. Annu Rev Biomed Eng. 2000;2:691-713.	82	72
1991	Sah RL-Y, Doong J-YH, Grodzinsky AJ, Plaas AHK, Sandy JD. Effects of compression on the loss of newly synthesized proteoglycans and proteins from cartilage explants. Arch Biochem Biophys. April 1991;286(1):209-29.	75	42
1994	Sah RL, Chen AC, Grodzinsky AJ, Trippel SB. Differential effects of bFGF and IGF-I on matrix metabolism in calf and adult bovine cartilage explants. Arch Biochem Biophys. January 1994;308(1):137-147.	38	13
1994	Kim Y-J, Sah RLY, Grodzinsky AJ, Plaas AHK, Sandy JD. Mechanical regulation of cartilage biosynthetic behavior: physical stimuli. Arch Biochem Biophys. May 1994;311(1):1-12.	135	97
1996	Kim Y-J, Grodzinsky AJ, Plaas AHK. Compression of cartilage results in differential effects on biosynthetic pathways for aggrecan, link protein, and hyaluronan. Arch Biochem Biophys. April 15, 1996;328(2):331-340.	31	16
1999	Buschmann MD, Kim Y-J, Wong M, Frank E, Hunziker EB, Grodzinsky AJ. Stimulation of aggrecan synthesis in cartilage explants by cyclic loading is localized to regions of high interstitial fluid flow1. Arch Biochem Biophys. June 1, 1999;366(1):1-7.	94	78
2000	Bonassar LJ, Grodzinsky AJ, Srinivasan A, Davila SG, Trippel SB. Mechanical and physicochemical regulation of the action of insulin-like growth factor-I on articular cartilage. Arch Biochem Biophys. July 1, 2000;379(1):57-63.	35	26
2000	Loening AM, James IE, Levenston ME, Badger AM, Frank EH, Kurz B, Nuttall ME, Hung H-H, Blake SM, Grodzinsky AJ, Lark MW. Injurious mechanical compression of bovine articular cartilage induces chondrocyte apoptosis. Arch Biochem Biophys. September 15, 2000;381(2):205-212.	62	45
2000	Ragan PM, Chin VI, Hung H-HK, Masuda K, Thonar EJ-MA, Arner EC, Grodzinsky AJ, Sandy JD. Chondrocyte extracellular matrix synthesis and turnover are influenced by static compression in a new alginate disk culture system. Arch Biochem Biophys. November 15, 2000;383(2):256-264.	40	27
2001	Jin M, Frank EH, Quinn TM, Hunziker EB, Grodzinsky AJ. Tissue shear deformation stimulates proteoglycan and protein biosynthesis in bovine cartilage explants. Arch Biochem Biophys. November 1, 2001;395(1):41-48.	65	54
1995	Bonassar LJ, Frank EH, Murray JC, Paguio CG, Moore VL, Lark MW, Sandy JD, Wu J-J, Eyre DR, Grodzinsky AJ. Changes in cartilage composition and physical properties due to stromelysin degradation. Arthritis Rheum. February 1995;38(2):173-183.	32	21
2003	Patwari P, Cook MN, DiMicco MA, Blake SM, James IE, Kumar S, Cole AA, Lark MW, Grodzinsky AJ. Proteoglycan degradation after injurious compression of bovine and human articular cartilage in vitro: interaction with exogenous cytokines. Arthritis Rheum. May 2003;48(5):1292-1301.	34	19
2005	Lee JH, Fitzgerald JB, DiMicco MA, Grodzinsky AJ. Mechanical injury of cartilage explants causes specific time-dependent changes in chondrocyte gene expression. Arthritis Rheum. August 2005;52(8):2386-2395.	29	22
1989	Gray ML, Pizzanelli AM, Lee RC, Grodzinsky AJ, Swann DA. Kinetics of the chondrocyte biosynthetic response to compressive load and release. Biochim Biophys Acta. June 27, 1989;991(3):415-425.	47	35
2014	Bajpayee AG, Wong CR, Bawendi MG, Frank EH, Grodzinsky AJ. Avidin as a model for charge driven transport into cartilage and drug delivery for treating early stage post-traumatic osteoarthritis. Biomaterials. January 2014;35(1):538-549.	20	11
2004	Fitzgerald JB, Jin M, Dean D, Wood DJ, Zheng MH, Grodzinsky AJ. Mechanical compression of cartilage explants induces multiple time-dependent gene expression patterns and involves intracellular calcium and cyclic AMP. J Biol Chem. May 7, 2004;279(19):19502-19511.	35	23
1987	Frank EH, Grodzinsky AJ. Cartilage electromechanics, I: electrokinetic transduction and the effects of electrolyte pH and ionic strength. J Biomech. 1987;20(6):615-627.	103	68
1987	Frank EH, Grodzinsky AJ. Cartilage electromechanics, II: a continuum model of cartilage electrokinetics and correlation with experiments. J Biomech. 1987;20(6):629-639.	119	89
1995	Kim Y-J, Bonassar LJ, Grodzinsky AJ. The role of cartilage streaming potential, fluid flow and pressure in the stimulation of chondrocyte biosynthesis during dynamic compression. J Biomech. September 1995;28(9):1055-1066.	107	77
2000	Frank EH, Jin M, Loening AM, Levenston ME, Grodzinsky AJ. A versatile shear and compression apparatus for mechanical stimulation of tissue culture explants. J Biomech. November 2000;33(11):1523-1527.	54	30
2004	Kisiday JD, Jin M, DiMicco MA, Kurz B, Grodzinsky AJ. Effects of dynamic compressive loading on chondrocyte biosynthesis in self-assembling peptide scaffolds. J Biomech. May 2004;37(5):595-604.	34	28
2023	Szapary HJ, Flaman L, Frank E, Chubinskaya S, Dwivedi G, Grodzinsky AJ. Effects of dexamethasone and dynamic loading on cartilage of human osteochondral explants challenged with inflammatory cytokines. J Biomech. March 2023;149:111480.	0	0
1981	Grodzinsky AJ, Roth V, Myers E, Grossman WD, Mow VC. The significance of electromechanical and osmotic forces in the nonequilibrium swelling behavior of articular cartilage in tension. J Biomech Eng. November 1981;103(4):221-231.	41	22
1987	Eisenberg SR, Grodzinsky AJ. The kinetics of chemically induced nonequilibrium swelling of articular cartilage and corneal stroma. J Biomech Eng. February 1987;109(1):79-89.	34	25
1995	Buschmann MD, Grodzinsky AJ. A molecular model of proteoglycan-associated electrostatic forces in cartilage mechanics. J Biomech Eng. May 1995;117(2):179-192.	90	63
1995	Buschmann MD, Gluzband YA, Grodzinsky AJ, Hunziker EB. Mechanical compression modulates matrix biosynthesis in chondrocyte/agarose culture. J Cell Sci. April 1995;108(4):1497-1508.	163	145
1996	Buschmann MD, Hunziker EB, Kim YJ, Grodzinsky AJ. Altered aggrecan synthesis correlates with cell and nucleus structure in statically compressed cartilage. J Cell Sci. February 1996;109(2):499-508.	48	39
1998	Quinn TM, Grodzinsky AJ, Buschmann MD, Kim YJ, Hunziker EB. Mechanical compression alters proteoglycan deposition and matrix deformation around individual cells in cartilage explants. J Cell Sci. March 1998;111(5):573-583.	62	42
1981	Lee RC, Frank EH, Grodzinsky AJ, Roylance DK. Oscillatory compressional behavior of articular cartilage and its associated electromechanical properties. J Biomech Eng. November 1981;103(2):280-292.	83	64
1983	Hoch DH, Grodzinsky AJ, Koob TJ, Albert ML, Eyre DR. Early changes in material properties of rabbit articular cartilage after meniscectomy. J Orthop Res. 1983;1(1):4-12.	73	58
1985	Eisenberg SR, Grodzinsky AJ. Swelling of articular cartilage and other connective tissues: electromechanochemical forces. J Orthop Res. 1985;3(2):148-159.	95	69
1987	Frank EH, Grodzinsky AJ, Koob TJ, Eyre DR. Streaming potentials: a sensitive index of enzymatic degradation in articular cartilage. J Orthop Res. 1987;5(4):497-508.	60	47
1988	Gray ML, Pizzanelli AM, Grodzinsky AJ, Lee RC. Mechanical and physicochemical determinants of the chondrocyte biosynthetic response. J Orthop Res. November 1988;6(6):777-792.	139	113
1989	Sah RL-Y, Kim Y-J, Doong J-YH, Grodzinsky AJ, Plass AHK, Sandy JD. Biosynthetic response of cartilage explants to dynamic compression. J Orthop Res. 1989;7(5):619-636.	257	184
1992	Buschmann MD, Gluzband YA, Grodzinsky AJ, Kimura JH, Hunziker EB. Chondrocytes in agarose culture synthesize a mechanically functional extracellular matrix. J Orthop Res. November 1992;10(6):745-758.	113	94
1996	Sah RL, Trippel SB, Grodzinsky AJ. Differential effects of serum, insulin-like growth factor-I, and fibroblast growth factor-2 on the maintenance of cartilage physical properties during long-term culture. J Orthop Res. January 1996;14(1):44-52.	34	12
1998	Quinn TM, Grodzinsky AJ, Hunziker EB, Sandy JD. Effects of injurious compression on matrix turnover around individual cells in calf articular cartilage explants. J Orthop Res. July 1998;16(4):490-499.	48	28
1999	Vunjak-Novakovic G, Martin I, Obradovic B, Treppo S, Grodzinsky AJ, Langer R, Freed LE. Bioreactor cultivation conditions modulate the composition and mechanical properties of tissue-engineered cartilage. J Orthop Res. January 1999;17(1):130-138.	104	95
1999	Ragan PM, Badger AM, Cook M, Chin VI, Gowen M, Grodzinsky AJ, Lark MW. Down-regulation of chondrocyte aggrecan and type-II collagen gene expression correlates with increases in static compression magnitude and duration. J Orthop Res. November 1999;17(6):836-842.	41	30
2000	Treppo S, Koepp H, Quan EC, Cole AA, Kuettner KE, Grodzinsky AJ. Comparison of biomechanical and biochemical properties of cartilage from human knee and ankle pairs. J Orthop Res. September 2000;18(5):739-748.	49	39
2000	Lee CR, Grodzinsky AJ, Hsu H-P, Martin SD, Spector M. Effects of harvest and selected cartilage repair procedures on the physical and biochemical properties of articular cartilage in the canine knee. J Orthop Res. September 2000;18(5):790-799.	22	20
2001	Bonassar LJ, Grodzinsky AJ, Frank EH, Davila SG, Bhaktav NR, Trippel SB. The effect of dynamic compression on the response of articular cartilage to insulin-like growth factor-i. J Orthop Res. January 2001;19(1):11-17.	70	58
2001	Kurz B, Jin M, Patwari P, Cheng DM, Lark MW, Grodzinsky AJ. Biosynthetic response and mechanical properties of articular cartilage after injurious compression. J Orthop Res. 2001;19(6):1140-1146.	52	37
2020	Connizzo BK, Grodzinsky AJ. Lose‐dose administration of dexamethasone is beneficial in preventing secondary tendon damage in a stress‐deprived joint injury explant model. J Orthop Res. January 2020;38(1):139-149.	1	1
2022	Orozco GA, Eskelinen ASA, Kosonen JP, Tanaka MS, Yang M, Link TM, Ma B, Li X, Grodzinsky AJ, Korhonen RK, Tanska P. Shear strain and inflammation-induced fixed charge density loss in the knee joint cartilage following ACL injury and reconstruction: a computational study. J Orthop Res. July 2022;40(7):1505-1522.	0	0
2003	Ng L, Grodzinsky AJ, Patwari P, Sandy J, Plaas A, Ortiz C. Individual cartilage aggrecan macromolecules and their constituent glycosaminoglycans visualized via atomic force microscopy. J Struct Biol. September 2003;143(3):242-257.	28	15
1978	Grodzinsky AJ, Lipshitz H, Glimcher MJ. Electromechanical properties of articular cartilage during compression and stress relaxation. Nature. October 5, 1978;275(5679):448-450.	36	24

Year

Article

Times Cited

Times Cited (no self-citations)

1990

Frank EH, Grodzinsky AJ, Phillips SL, Grimshaw PE. Physicochemical and bioelectrical determinants of cartilage material properties. In: Mow VC, Ratcliffe A, Woo SL-Y, eds. Biomechanics of Diarthrodial Joints. Vol 1. New York, NY: Springer-Verlag; 1990:261-282.

1988

Kim Y-J, Sah RLY, Doong J-YH, Grodzinsky AJ. Fluorometric assay of DNA in cartilage explants using Hoechst 33258. Anal Ciochem. October 1988;174(1):168-176.

141

2000

Grodzinsky AJ, Levenston ME, Jin M, Frank EH. Cartilage tissue remodeling in response to mechanical forces. Annu Rev Biomed Eng. 2000;2:691-713.

1991

Sah RL-Y, Doong J-YH, Grodzinsky AJ, Plaas AHK, Sandy JD. Effects of compression on the loss of newly synthesized proteoglycans and proteins from cartilage explants. Arch Biochem Biophys. April 1991;286(1):209-29.

1994

Sah RL, Chen AC, Grodzinsky AJ, Trippel SB. Differential effects of bFGF and IGF-I on matrix metabolism in calf and adult bovine cartilage explants. Arch Biochem Biophys. January 1994;308(1):137-147.

1994

Kim Y-J, Sah RLY, Grodzinsky AJ, Plaas AHK, Sandy JD. Mechanical regulation of cartilage biosynthetic behavior: physical stimuli. Arch Biochem Biophys. May 1994;311(1):1-12.

135

1996

Kim Y-J, Grodzinsky AJ, Plaas AHK. Compression of cartilage results in differential effects on biosynthetic pathways for aggrecan, link protein, and hyaluronan. Arch Biochem Biophys. April 15, 1996;328(2):331-340.

1999

Buschmann MD, Kim Y-J, Wong M, Frank E, Hunziker EB, Grodzinsky AJ. Stimulation of aggrecan synthesis in cartilage explants by cyclic loading is localized to regions of high interstitial fluid flow1. Arch Biochem Biophys. June 1, 1999;366(1):1-7.

2000

Bonassar LJ, Grodzinsky AJ, Srinivasan A, Davila SG, Trippel SB. Mechanical and physicochemical regulation of the action of insulin-like growth factor-I on articular cartilage. Arch Biochem Biophys. July 1, 2000;379(1):57-63.

2000

Loening AM, James IE, Levenston ME, Badger AM, Frank EH, Kurz B, Nuttall ME, Hung H-H, Blake SM, Grodzinsky AJ, Lark MW. Injurious mechanical compression of bovine articular cartilage induces chondrocyte apoptosis. Arch Biochem Biophys. September 15, 2000;381(2):205-212.

2000

Ragan PM, Chin VI, Hung H-HK, Masuda K, Thonar EJ-MA, Arner EC, Grodzinsky AJ, Sandy JD. Chondrocyte extracellular matrix synthesis and turnover are influenced by static compression in a new alginate disk culture system. Arch Biochem Biophys. November 15, 2000;383(2):256-264.

2001

Jin M, Frank EH, Quinn TM, Hunziker EB, Grodzinsky AJ. Tissue shear deformation stimulates proteoglycan and protein biosynthesis in bovine cartilage explants. Arch Biochem Biophys. November 1, 2001;395(1):41-48.

1995

Bonassar LJ, Frank EH, Murray JC, Paguio CG, Moore VL, Lark MW, Sandy JD, Wu J-J, Eyre DR, Grodzinsky AJ. Changes in cartilage composition and physical properties due to stromelysin degradation. Arthritis Rheum. February 1995;38(2):173-183.

2003

Patwari P, Cook MN, DiMicco MA, Blake SM, James IE, Kumar S, Cole AA, Lark MW, Grodzinsky AJ. Proteoglycan degradation after injurious compression of bovine and human articular cartilage in vitro: interaction with exogenous cytokines. Arthritis Rheum. May 2003;48(5):1292-1301.

2005

Lee JH, Fitzgerald JB, DiMicco MA, Grodzinsky AJ. Mechanical injury of cartilage explants causes specific time-dependent changes in chondrocyte gene expression. Arthritis Rheum. August 2005;52(8):2386-2395.

1989

Gray ML, Pizzanelli AM, Lee RC, Grodzinsky AJ, Swann DA. Kinetics of the chondrocyte biosynthetic response to compressive load and release. Biochim Biophys Acta. June 27, 1989;991(3):415-425.

2014

Bajpayee AG, Wong CR, Bawendi MG, Frank EH, Grodzinsky AJ. Avidin as a model for charge driven transport into cartilage and drug delivery for treating early stage post-traumatic osteoarthritis. Biomaterials. January 2014;35(1):538-549.

2004

Fitzgerald JB, Jin M, Dean D, Wood DJ, Zheng MH, Grodzinsky AJ. Mechanical compression of cartilage explants induces multiple time-dependent gene expression patterns and involves intracellular calcium and cyclic AMP. J Biol Chem. May 7, 2004;279(19):19502-19511.

1987

Frank EH, Grodzinsky AJ. Cartilage electromechanics, I: electrokinetic transduction and the effects of electrolyte pH and ionic strength. J Biomech. 1987;20(6):615-627.

103

1987

Frank EH, Grodzinsky AJ. Cartilage electromechanics, II: a continuum model of cartilage electrokinetics and correlation with experiments. J Biomech. 1987;20(6):629-639.

119

1995

Kim Y-J, Bonassar LJ, Grodzinsky AJ. The role of cartilage streaming potential, fluid flow and pressure in the stimulation of chondrocyte biosynthesis during dynamic compression. J Biomech. September 1995;28(9):1055-1066.

107

2000

Frank EH, Jin M, Loening AM, Levenston ME, Grodzinsky AJ. A versatile shear and compression apparatus for mechanical stimulation of tissue culture explants. J Biomech. November 2000;33(11):1523-1527.

2004

Kisiday JD, Jin M, DiMicco MA, Kurz B, Grodzinsky AJ. Effects of dynamic compressive loading on chondrocyte biosynthesis in self-assembling peptide scaffolds. J Biomech. May 2004;37(5):595-604.

2023

Szapary HJ, Flaman L, Frank E, Chubinskaya S, Dwivedi G, Grodzinsky AJ. Effects of dexamethasone and dynamic loading on cartilage of human osteochondral explants challenged with inflammatory cytokines. J Biomech. March 2023;149:111480.

1981

Grodzinsky AJ, Roth V, Myers E, Grossman WD, Mow VC. The significance of electromechanical and osmotic forces in the nonequilibrium swelling behavior of articular cartilage in tension. J Biomech Eng. November 1981;103(4):221-231.

1987

Eisenberg SR, Grodzinsky AJ. The kinetics of chemically induced nonequilibrium swelling of articular cartilage and corneal stroma. J Biomech Eng. February 1987;109(1):79-89.

1995

Buschmann MD, Grodzinsky AJ. A molecular model of proteoglycan-associated electrostatic forces in cartilage mechanics. J Biomech Eng. May 1995;117(2):179-192.

1995

Buschmann MD, Gluzband YA, Grodzinsky AJ, Hunziker EB. Mechanical compression modulates matrix biosynthesis in chondrocyte/agarose culture. J Cell Sci. April 1995;108(4):1497-1508.

163

145

1996

Buschmann MD, Hunziker EB, Kim YJ, Grodzinsky AJ. Altered aggrecan synthesis correlates with cell and nucleus structure in statically compressed cartilage. J Cell Sci. February 1996;109(2):499-508.

1998

Quinn TM, Grodzinsky AJ, Buschmann MD, Kim YJ, Hunziker EB. Mechanical compression alters proteoglycan deposition and matrix deformation around individual cells in cartilage explants. J Cell Sci. March 1998;111(5):573-583.

1981

Lee RC, Frank EH, Grodzinsky AJ, Roylance DK. Oscillatory compressional behavior of articular cartilage and its associated electromechanical properties. J Biomech Eng. November 1981;103(2):280-292.

1983

Hoch DH, Grodzinsky AJ, Koob TJ, Albert ML, Eyre DR. Early changes in material properties of rabbit articular cartilage after meniscectomy. J Orthop Res. 1983;1(1):4-12.

1985

Eisenberg SR, Grodzinsky AJ. Swelling of articular cartilage and other connective tissues: electromechanochemical forces. J Orthop Res. 1985;3(2):148-159.

1987

Frank EH, Grodzinsky AJ, Koob TJ, Eyre DR. Streaming potentials: a sensitive index of enzymatic degradation in articular cartilage. J Orthop Res. 1987;5(4):497-508.

1988

Gray ML, Pizzanelli AM, Grodzinsky AJ, Lee RC. Mechanical and physicochemical determinants of the chondrocyte biosynthetic response. J Orthop Res. November 1988;6(6):777-792.

139

113

1989

Sah RL-Y, Kim Y-J, Doong J-YH, Grodzinsky AJ, Plass AHK, Sandy JD. Biosynthetic response of cartilage explants to dynamic compression. J Orthop Res. 1989;7(5):619-636.

257

184

1992

Buschmann MD, Gluzband YA, Grodzinsky AJ, Kimura JH, Hunziker EB. Chondrocytes in agarose culture synthesize a mechanically functional extracellular matrix. J Orthop Res. November 1992;10(6):745-758.

113

1996

Sah RL, Trippel SB, Grodzinsky AJ. Differential effects of serum, insulin-like growth factor-I, and fibroblast growth factor-2 on the maintenance of cartilage physical properties during long-term culture. J Orthop Res. January 1996;14(1):44-52.

1998

Quinn TM, Grodzinsky AJ, Hunziker EB, Sandy JD. Effects of injurious compression on matrix turnover around individual cells in calf articular cartilage explants. J Orthop Res. July 1998;16(4):490-499.

1999

Vunjak-Novakovic G, Martin I, Obradovic B, Treppo S, Grodzinsky AJ, Langer R, Freed LE. Bioreactor cultivation conditions modulate the composition and mechanical properties of tissue-engineered cartilage. J Orthop Res. January 1999;17(1):130-138.

104

1999

Ragan PM, Badger AM, Cook M, Chin VI, Gowen M, Grodzinsky AJ, Lark MW. Down-regulation of chondrocyte aggrecan and type-II collagen gene expression correlates with increases in static compression magnitude and duration. J Orthop Res. November 1999;17(6):836-842.

2000

Treppo S, Koepp H, Quan EC, Cole AA, Kuettner KE, Grodzinsky AJ. Comparison of biomechanical and biochemical properties of cartilage from human knee and ankle pairs. J Orthop Res. September 2000;18(5):739-748.

2000

Lee CR, Grodzinsky AJ, Hsu H-P, Martin SD, Spector M. Effects of harvest and selected cartilage repair procedures on the physical and biochemical properties of articular cartilage in the canine knee. J Orthop Res. September 2000;18(5):790-799.

2001

Bonassar LJ, Grodzinsky AJ, Frank EH, Davila SG, Bhaktav NR, Trippel SB. The effect of dynamic compression on the response of articular cartilage to insulin-like growth factor-i. J Orthop Res. January 2001;19(1):11-17.

2001

Kurz B, Jin M, Patwari P, Cheng DM, Lark MW, Grodzinsky AJ. Biosynthetic response and mechanical properties of articular cartilage after injurious compression. J Orthop Res. 2001;19(6):1140-1146.

2020

Connizzo BK, Grodzinsky AJ. Lose‐dose administration of dexamethasone is beneficial in preventing secondary tendon damage in a stress‐deprived joint injury explant model. J Orthop Res. January 2020;38(1):139-149.

2022

Orozco GA, Eskelinen ASA, Kosonen JP, Tanaka MS, Yang M, Link TM, Ma B, Li X, Grodzinsky AJ, Korhonen RK, Tanska P. Shear strain and inflammation-induced fixed charge density loss in the knee joint cartilage following ACL injury and reconstruction: a computational study. J Orthop Res. July 2022;40(7):1505-1522.

2003

Ng L, Grodzinsky AJ, Patwari P, Sandy J, Plaas A, Ortiz C. Individual cartilage aggrecan macromolecules and their constituent glycosaminoglycans visualized via atomic force microscopy. J Struct Biol. September 2003;143(3):242-257.

1978

Grodzinsky AJ, Lipshitz H, Glimcher MJ. Electromechanical properties of articular cartilage during compression and stress relaxation. Nature. October 5, 1978;275(5679):448-450.

Year	Article	Times Cited	Times Cited (no self-citations)
1974	Grodzinsky AJ. Electromechanics of Deformable Polyelectrolyte Membranes Cambridge, MA: Massachusetts Institute of Technology; June 1974.	0	0

Year

Article

Times Cited

Times Cited (no self-citations)

1974

Grodzinsky AJ. Electromechanics of Deformable Polyelectrolyte Membranes Cambridge, MA: Massachusetts Institute of Technology; June 1974.

Year	Article	Times Cited	Times Cited (no self-citations)
2020	Krishnan Y. Intra/extracellular Multi-Drug Delivery for Osteoarthritis [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; September 2020.	0	0
2019	Geiger BC. Designing Nanocarriers to Penetrate Cartilage and Improve Delivery of Biologic Drugs for Osteoarthritis [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; February 2019.	0	0
2017	Ibañez JR. Use of Synthetic Solid Scaffolds to Mechanically Support a Chondrocyte-Seeded Peptide Hydrogel for Articular Cartilage Repair [Master's thesis]. Cambridge, MA: Massachusetts Institute of Technology; June 2017.	0	0
2016	Young WT. Cartilage Stress Relaxation Induced by Intra-Tissue Transport of Cationic Nanoparticles: Implications for Post-Traumatic Osteoarthritis Drug Delivery [Master's thesis]. Cambridge, MA: Massachusetts Institute of Technology; June 2016.	0	0
2016	Wang Y. Molecular Pathway Analysis and Therapeutics Development in Post-Traumatic Osteoarthritis [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; September 2016.	0	0
2016	Liebesny PH. Single-Dose Growth Factor Treatments to Enhance Cell Recruitment and Neotissue Integration in an Augmented Microfracture Cartilage Repair Model [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; June 2016.	1	0
2015	Bajpayee AG. Charge-Based Transport and Drug Delivery Into Cartilage for Localized Treatment of Degenerative Joint Diseases [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; February 2015.	1	0
2013	Nia HT. Nanomechanics of Cartilage At the Matrix and Molecular Levels [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; June 2013.	0	0
2013	Li Y. In Vitro Model of Injury/cytokine-Induced Cartilage Catabolism Modulated by Dynamic Compression, Growth Factors, and Glucocorticoids [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; June 2013.	1	0
2012	Florine EM. Optimizing Chondrogenic Factors and Protein Delivery Methods for Cartilage Repair [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; June 2012.	0	0
2010	Miller RE. In Vitro and in Vivo Growth Factor Delivery to Chondrocytes and Bone-Marrow-Derived Stromal Cells in Cartilage and in Self-Assembling Peptide Scaffolds [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; June 2010.	0	0
2010	Lu YCS. In Vitro Models of Cartilage Degradation Following Joint Injury: Mechanical Overload, Inflammatory Cytokines and Therapeutic Approaches [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; February 2010.	0	0
2010	Lee H-Y. Ultrastructure and Nanomechanical Properties of Aggrecan from Native Cartilage and Engineered Tissue [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; June 2010.	0	0
2010	Byun S. Transport of Proteins, Biopharmaceuticals and Small Pharmaceutical Compounds Into Normal and Injured Cartilage [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; June 2010.	0	0
2009	Lee B. Time-Dependent Mechanical Behavior of Newly Developing Matrix of Bovine Primary Chondrocytes and Bone Marrow Stromal Cells Using Atomic Force Microscopy [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; September 2009.	0	0
2009	Kopesky PW. Self-Assembling Peptide Hydrogels Promote in Vitro Chondrogenesis of Bone Marrow-Derived Stromal Cells: Effects of Peptide Sequence, Cell Donor Age, and Method of Growth Factor Delivery [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; June 2009.	0	0
2009	Chen S. Regulation of Lubricin Gene Expression and Synthesis in Cartilage by Mechanical Injury [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; September 2009.	0	0
2008	Wheeler CA. Cartilage Response to in Vitro Models of Injury in Combination With Growth Factor and Antioxidant Treatments [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; February 2008.	0	0
2008	Chai DH. Progression of Chondrocyte Signaling Responses to Mechanical Stimulation in 3-D Gel Culture [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; February 2008.	0	0
2007	Han L. Nanomechanics of Cartilage Extracellular Matrix Macromolecules [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; September 2007.	0	0
2006	Stevens AL. Mechanical Injury and Inflammatory Cytokines Affect Cartilage Integrity and Tissue Homeostasis: A Mass Spectrometric Analysis of Proteins With Relevance to Arthritis [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; September 2006.	0	0
2005	Szafranski JD. Cartilage Mechanobiology: The Effects of Loading on the Fine Structure and Function of Chondroitin Sulfate Glycosaminoglycans [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; June 2005.	0	0
2005	Ng LJ. Probing Nanomechanics of Aggrecan and the Aggrecan-Rich Pericellular Matrix of Chondrocytes in Cartilage [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; September 2005.	0	0
2005	Lee JH. Chondrocyte Response to in Vitro Mechanical Injury and Co-Culture With Joint Capsule Tissue [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; June 2005.	2	0
2005	FitzGerald JB. Chondrocyte Gene Expression and Intracellular Signaling Pathways in Cartilage Mechanotransduction [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; July 2005.	1	1
2005	Dean DMD. Modeling and Measurement of Intermolecular Interaction Forces Between Cartilage ECM Macromolecules [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; February 2005.	0	0
2004	Bathe M. Inverse Monte Carlo Simulation of Biomolecular Conformation and Coarse-Grained Molecular Modeling of Chondroitin Sulfate Conformation, Titration, and Osmotic Pressure [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; June 2004.	0	0
2003	Szász N. Electric Field Regulation of Chondrocyte Proliferation, Biosynthesis, and Cellular Signaling [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; 2003.	0	0
2003	Seog J. Molecular Mechanics of Cartilage: Quantification of GAG Electrostatic Interactions Via High-Resolution Force Spectroscopy Cambridge, MA: Massachusetts Institute of Technology; June 2003.	0	0
2003	Patwari P. In Vitro Models for Injurious Compression of Bovine and Human Articular Cartilage Cambridge, MA: Massachusetts Institute of Technology; June 2003.	0	0
2003	Kisiday JD. In Vitro Culture of a Chondrocyte-Seeded Peptide Hydrogel and the Effects of Dynamic Compression [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; June 2003.	0	0
2002	Lee CR. Behavior of Passaged Chondrocytes in Collagen-Glycosaminoglycan Scaffolds: Effects of Cross-Linking, Mechanical Loading, and Genetic Modification of the Scaffold [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; February 2002.	0	0
2002	Jin M. Chondrocyte Metabolism and Matrix Nano-Electromechanics: The Response to Cartilage Tissue Shear Deformation Cambridge, MA: Massachusetts Institute of Technology; February 2002.	0	0
1999	Treppo S. Physical Diagnostics of Cartilage Degeneration [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; February 1999.	0	0
1999	Szász N. Transport and Binding of Insulin-Like Growth Factors to Articular Cartilage [Master's thesis]. Cambridge, MA: Massachusetts Institute of Technology; June 1999.	0	0
1999	Ragan PM. The Effect of Mechanical Compression on Chondrocyte Gene Expression [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; May 1999.	0	0
1996	Quinn TM. Articular Cartilage: Matrix Assembly, Mediation of Chondrocyte Metabolism, and Response to Compression [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; May 1996.	3	0
1996	García AM. Mechanisms of Macromolecular Transport Through Articular Cartilage: Relevance to Loading [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; June 1996.	0	0
1996	Berkenblit SI. Spatial Localization of Cartilage Degradation Using Electromechanical Surface Spectroscopy With Variable Wavelength and Frequency [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; June 1996.	1	0
1995	Bonassar LJ. Matrix Metalloproteinase Activity and Inhibition in Articular Cartilage: Effects on Composition and Biophysical Properties and Relevance to Osteoarthritis [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; February 1995.	0	0
1994	Chang Y-HD. Augmentation of Mass Transfer Through Electrical Means and Nutrient Enrichment for Suspension and Entrapment Cell Cultures [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; May 1994.	0	0
1993	Kim Y-J. Physical Regulation of Cartilage Metabolism: Effects of Compression on Specific Matrix Molecules and Their Spatial Distribution [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; 1993.	0	0
1992	Buschmann MD. Chondrocytes in Agarose Culture: Development of a Mechanically Functional Matrix, Biosynthetic Response to Compression, and Molecular Model of the Modulus [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; 1992.	8	1
1990	Sah RL-Y. Biophysical Regulation of Matrix Systhesis, Assembly, and Degradation in Dynamically Compressed Calf Cartilage [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; 1990.	1	0
1989	Grimshaw PE. Electrical Control of Solute Transport Across Polyelectrolyte Membranes [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; February 1989.	1	0
1988	MacGinitie LA. Electrical and Thermal Modulation of Protein Synthesis in Cartilage: A Model for Field Effects on Biological Tissues [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; January 1988.	0	0
1987	Sachs JR. A Mathematical Model of an Electromechanically Coupled Poroelastic Medium [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; June 1987.	2	0
1987	Frank EH. Electromechanics of Normal and Degenerated Cartilage: Poroelastic Behavior and Electrokinetic Mechanisms [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; May 1987.	4	0
1986	Weiss AM. Real-Time Control of the Permeability of Crosslinked Polyelectrolyte Membranes to Fluorescent Solutes [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; 1986.	1	0
1986	Nussbaum JH. Electric Field Control of Mechanical and Electrochemical Properties of Polyelectrolyte Gel Membranes Cambridge, MA: Massachusetts Institute of Technology; August 1986.	3	0
1986	Gray ML. Physical Regulation of Epiphyseal Cartilage Biosynthesis: Responses to Electrical, Mechanical, and Chemical Signals [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; July 1986.	6	1
1984	Siegel RA. Macromolecular Drug Release from Porous Implants: Sources of Matrix Tortuosity Cambridge, MA: Massachusetts Institute of Technology; February 1984.	0	0
1983	Eisenberg SR. Nonequilibrium Electromechanical Interactions in Cartilage: Swelling and Electrokinetics Cambridge, MA: Massachusetts Institute of Technology; February 1983.	7	2
1980	Lee RC. Cartilage Electromechanics: The Relationship of Physicochemical to Mechanical Properties Cambridge, MA: Massachusetts Institute of Technology; 1980.	0	0
2018	Wallace C. Effects of Glucocorticoids on Chondrocytes and Cartilage [Master's thesis]. Boston University; 2018.	0	0

Name	Count	Oldest	Newest
Martin, Ivan	1	1999	1999
Langer, Robert S.	1	1999	1999
Masuda, Koichi	1	2000	2000
Thonar, Eugene Jean-Marie Antoine	1	2000	2000
Lark, Michael William	5	1995	2003
Mow, Van C.	1	1981	1981
Vunjak-Novakovic, Gordana	1	1999	1999
Kuettner, Klaus E.	1	2000	2000
Eisenberg, Solomon R.	2	1985	1987
Bonassar, Lawrence Justin	4	1995	2001
Frank, Eliot H.	14	1981	2023
Kim, Young-Jo	8	1988	1999
Dean, Delphine M. D.	1	2004	2004
Lee, Raphael C.	2	1988	1989
Hunziker, Ernst B.	7	1992	2001
Link, Thomas M.	1	2022	2022
Ortiz, Christine	1	2003	2003
Myers, Elizabeth R.	1	1981	1981
Bajpayee, Ambika G.	1	2014	2014
Sah, Robert L.-Y.	6	1988	1996
Jin, Moonsoo M.	6	2000	2004
Zenobi-Wong, Marcy	1	1999	1999
Sandy, John D.	7	1989	2003
Eyre, David R.	3	1983	1995
Kisiday, John D.	1	2004	2004
Korhonen, Rami K.	1	2022	2022
Kurz, Bodo	3	2000	2004
Kimura, James Hiroshi	1	1992	1992
Chen, Albert C.	1	1994	1994
Glimcher, Melvin Jacob	1	1978	1978
Levenston, Marc E.	3	2000	2000
Quinn, Thomas M.	3	1998	2001
Gray, Martha L.	2	1988	1989
Freeman, Lisa Ernestine	1	1999	1999
Buschmann, Michael D.	6	1992	1999
Plaas, Anna H. K.	4	1991	2003

Name

Count

Oldest

Newest

Martin, Ivan

1999

Langer, Robert S.

1999

Masuda, Koichi

2000

Thonar, Eugene Jean-Marie Antoine

2000