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Lee, BoBae
Time-Dependent Mechanical Behavior of Newly Developing Matrix of Bovine Primary Chondrocytes and Bone Marrow Stromal Cells Using Atomic Force Microscopy
[PhD thesis].
Cambridge, MA: Massachusetts Institute of Technology
Grodzinsky, Alan J.
;
Ortiz, Christine
(supervisors)
September 2009
Links
URL:
http://hdl.handle.net/1721.1/54571
OCLC:
1130072583
PROQUEST:
305098181
Cited Works (47)
Year
Entry
1999
Buschmann MD, Kim Y-J, Wong M, Frank E, Hunziker EB, Grodzinsky AJ. Stimulation of aggrecan synthesis in cartilage explants by cyclic loading is localized to regions of high interstitial fluid flow1.
Arch Biochem Biophys
. June 1, 1999;366(1):1-7.
2006
Guilak F, Alexopoulos LG, Upton ML, Youn I, Choi JB, Cao L, Setton LA, Haider MA. The pericellular matrix as a transducer of biomechanical and biochemical signals in articular cartilage.
Annals NY Acad Sci
. April 2006;1068(1):498-512.
2003
Ng L, Grodzinsky AJ, Patwari P, Sandy J, Plaas A, Ortiz C. Individual cartilage aggrecan macromolecules and their constituent glycosaminoglycans visualized via atomic force microscopy.
J Struct Biol
. September 2003;143(3):242-257.
2002
Guilak F, Erickson GR, Ting-Beall HP. The effects of osmotic stress on the viscoelastic and physical properties of articular chondrocytes.
Biophys J
. February 2002;82(2):720-727.
2000
Guilak F, Mow VC. The mechanical environment of the chondrocyte: a biphasic finite element model of cell–matrix interactions in articular cartilage.
J Biomech
. December 2000;33(12):1663-1673.
1992
Buschmann MD, Gluzband YA, Grodzinsky AJ, Kimura JH, Hunziker EB. Chondrocytes in agarose culture synthesize a mechanically functional extracellular matrix.
J Orthop Res
. November 1992;10(6):745-758.
2005
Leipzig ND, Athanasiou KA. Unconfined creep compression of chondrocytes.
J Biomech
. January 2005;38(1):77-85.
1982
Armstrong CG, Mow VC. Variations in the intrinsic mechanical properties of human articular cartilage with age, degeneration, and water content.
J Bone Joint Surg
. 1982;64A(1):88-94.
2003
Masuda K, Sah RL, Hejna MJ, Thonar EJ-MA. A novel two-step method for the formation of tissue-engineered cartilage by mature bovine chondrocytes: the alginate-recovered-chondrocyte (ARC) method.
J Orthop Res
. January 2003;21(1):139-148.
2004
Darling EM, Hu JCY, Athanasiou KA. Zonal and topographical differences in articular cartilage gene expression.
J Orthop Res
. November 2004;22(6):1182-1187.
1981
Lee RC, Frank EH, Grodzinsky AJ, Roylance DK. Oscillatory compressional behavior of articular cartilage and its associated electromechanical properties.
J Biomech Eng
. November 1981;103(2):280-292.
2006
Darling EM, Zauscher S, Guilak F. Viscoelastic properties of zonal articular chondrocytes measured by atomic force microscopy.
Osteoarthritis Cartilage
. June 2006;14(6):571-579.
2002
Wang CC-B, Guo XE, Sun D, Mow VC, Ateshian GA, Hung CT. The functional environment of chondrocytes within cartilage subjected to compressive loading: a theoretical and experimental approach.
Biorheology
. 2002;39(1-2):11-25.
1995
Bachrach NM, Valhmu WB, Stazzone E, Ratcliffe A, Lai WM, Mow VC. Changes in proteoglycan synthesis of chondrocytes in articular cartilage are associated with the time-dependent changes in their mechanical environment.
J Biomech
. December 1995;28(12):1561-1569.
1994
Freeman PM, Natarajan RN, Kimura JH, Andriacchi TP. Chondrocyte cells respond mechanically to compressive loads.
J Orthop Res
. May 1994;12(3):311-320.
1995
Buschmann MD, Grodzinsky AJ. A molecular model of proteoglycan-associated electrostatic forces in cartilage mechanics.
J Biomech Eng
. May 1995;117(2):179-192.
1961
Woessner JF Jr. The determination of hydroxyproline in tissue and protein samples containing small proportions of this imino acid.
Arch Biochem Biophys
. May 1961;93(2):440-447.
2000
Millward-Sadler SJ, Wright MO, Davies LW, Nuki G, Salter DM. Mechanotransduction via integrins and interleukin-4 results in altered aggrecan and matrix metalloproteinase 3 gene expression in normal, but not osteoarthritic, human articular chondrocytes.
Arthritis Rheum
. September 2000;43(9):2091-2099.
1997
Poole CA. Articular cartilage chondrons: form, function and failure.
J Anat
. 1997;191(1):1-13.
2000
Trickey WR, Lee GM, Guilak F. Viscoelastic properties of chondrocytes from normal and osteoarthritic human cartilage.
J Orthop Res
. November 2000;18(6):891-898.
1986
Farndale RW, Buttle DJ, Barrett AJ. Improved quantitation and discrimination of sulphated glycosaminoglycans by use of dimethylmethylene blue.
Biochim Biophys Acta
. September 4, 1986;883(2):173-177.
1980
Mow VC, Kuei SC, Lai WM, Armstrong CG. Biphasic creep and stress relaxation of articular cartilage in compression: theory and experiments.
J Biomech Eng
. February 1980;102(1):73-84.
1999
Rowley JA, Madlambayan G, Mooney DJ. Alginate hydrogels as synthetic extracellular matrix materials.
Biomaterials
. January 1999;20(1):45-53.
2003
Huang C-Y, Soltz MA, Kopacz M, Mow VC, Ateshian GA. Experimental verification of the roles of intrinsic matrix viscoelasticity and tension-compression nonlinearity in the biphasic response of cartilage.
J Biomech Eng
. February 2003;125(1):84-93.
2005
Alexopoulos LG, Setton LA, Guilak F. The biomechanical role of the chondrocyte pericellular matrix in articular cartilage.
Acta Biomater
. May 2005;1(3):317-325.
1978
Grodzinsky AJ, Lipshitz H, Glimcher MJ. Electromechanical properties of articular cartilage during compression and stress relaxation.
Nature
. October 5, 1978;275(5679):448-450.
1995
Buschmann MD, Gluzband YA, Grodzinsky AJ, Hunziker EB. Mechanical compression modulates matrix biosynthesis in chondrocyte/agarose culture.
J Cell Sci
. April 1995;108(4):1497-1508.
2000
Mauck RL, Soltz MA, Wang CCB, Wong DD, Chao P-HG, Valhmu WB, Hung CT, Ateshian GA. Functional tissue engineering of articular cartilage through dynamic loading of chondrocyte-seeded agarose gels.
J Biomech Eng
. June 2000;122(3):252-260.
2004
Trickey WR, Vail TP, Guilak F. The role of the cytoskeleton in the viscoelastic properties of human articular chondrocytes.
J Orthop Res
. January 2004;22(1):131-139.
2004
Awad HA, Wickham MQ, Leddy HA, Gimble JM, Guilak F. Chondrogenic differentiation of adipose-derived adult stem cells in agarose, alginate, and gelatin scaffolds.
Biomaterials
. July 2004;25(16):3211-3222.
1999
Wu JZ, Herzog W, Epstein M. Modelling of location- and time-dependent deformation of chondrocytes during cartilage loading.
J Biomech
. June 1999;32(6):563-572.
1981
Grodzinsky AJ, Roth V, Myers E, Grossman WD, Mow VC. The significance of electromechanical and osmotic forces in the nonequilibrium swelling behavior of articular cartilage in tension.
J Biomech Eng
. November 1981;103(4):221-231.
1994
Athanasiou KA, Agarwal A, Dzida FJ. Comparative study of the intrinsic mechanical properties of the human acetabular and femoral head cartilage.
J Orthop Res
. May 1994;12(3):340-349.
1995
Athanasiou KA, Agarwal A, Muffoletto A, Dzida FJ, Constantinides G, Clem M. Biomechanical properties of hip cartilage in experimental animal models.
Clin Orthop Relat Res
. July 1995;316:254-266.
2006
Shieh AC, Athanasiou KA. Biomechanics of single zonal chondrocytes.
J Biomech
. 2006;39(9):1595-1602.
2003
Koay EJ, Shieh AC, Athanasiou KA. Creep indentation of single cells.
J Biomech Eng
. June 2003;125(3):334-341.
1991
Athanasiou KA, Rosenwasser MP, Buckwalter JA, Malinin TI, Mow VC. Interspecies comparisons of in situ intrinsic mechanical properties of distal femoral cartilage.
J Orthop Res
. May 1991;9(3):330-340.
2005
Alexopoulos LG, Williams GM, Upton ML, Setton LA, Guilak F. Osteoarthritic changes in the biphasic mechanical properties of the chondrocyte pericellular matrix in articular cartilage.
J Biomech
. March 2005;38(3):509-517.
2000
Soltz MA, Ateshian GA. Interstitial fluid pressurization during confined compression cyclical loading of articular cartilage.
Ann Biomed Eng
. February 2000;28(2):150-159.
1998
Athanasiou KA, Liu GT, Lavery LA, Lanctot DR, Schenck RC Jr. Biomechanical topography of human articular cartilage in the first metatarsophalangeal joint.
Clin Orthop Relat Res
. 1998;348:269-281.
2003
Alexopoulos LG, Haider MA, Vail TP, Guilak F. Alterations in the mechanical properties of the human chondrocyte pericellular matrix with osteoarthritis.
J Biomech Eng
. June 2003;125(3):323-333.
1987
Frank EH, Grodzinsky AJ. Cartilage electromechanics, II: a continuum model of cartilage electrokinetics and correlation with experiments.
J Biomech
. 1987;20(6):629-639.
1995
Kim Y-J, Bonassar LJ, Grodzinsky AJ. The role of cartilage streaming potential, fluid flow and pressure in the stimulation of chondrocyte biosynthesis during dynamic compression.
J Biomech
. September 1995;28(9):1055-1066.
1987
Poole CA, Flint MH, Beaumont BW. Chondrons in cartilage: ultrastructural analysis of the pericellular microenvironment in adult human articular cartilages.
J Orthop Res
. 1987;5(4):509-522.
2008
Darling EM, Topel M, Zauscher S, Vail TP, Guilak F. Viscoelastic properties of human mesenchymally-derived stem cells and primary osteoblasts, chondrocytes, and adipocytes.
J Biomech
. 2008;41(2):454-464.
1997
Schinagl RM, Gurskis D, Chen AC, Sah RL. Depth-dependent confined compression modulus of full-thickness bovine articular cartilage.
J Orthop Res
. July 1997;15(4):499-506.
2004
Stolz M, Raiteri R, Daniels AU, VanLandingham MR, Baschong W, Aebi U. Dynamic elastic modulus of porcine articular cartilage determined at two different levels of tissue organization by indentation-type atomic force microscopy.
Biophys J
. May 2004;86(5):3269-3283.