Electromechanical properties of articular cartilage during compression and stress relaxation

Grodzinsky, A. J.<sup>1</sup>; Lipshitz, H.<sup>2</sup>; Glimcher, M. J.<sup>2</sup>

Affiliations

¹Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139

²Department of Orthopaedic Surgery, Children's Hospital Medical Center and Harvard Medical School, Boston, Massachusetts

Links

DOI: 10.1038/275448a0

PubMed: 29231

WoS: A1978FR32800040

History

Received: 1978-04-26

Accepted: 1978-07-31

Cited Works (4)

Year	Entry
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1962	McCutchen CW. The frictional properties of animal joints. Wear. January–February 1962;5(1):1-17.
1965	Linn FC, Sokoloff L. Movement and composition of interstitial fluid of cartilage. Arthritis Rheum. August 1965;8(4):481-494.
1971	Kempson GE, Freeman MAR, Swanson SAV. The determination of a creep modulus for articular cartilage from indentation tests on the human femoral head. J Biomech. July 1971;4(4):239-250.

Cited By (36)

Year	Entry
2003	Ateshian GA, Hung CT. Functional properties of native articular cartilage. In: Guilak F, Butler DL, Goldstein SA, Mooney DJ, eds. Functional Tissue Engineering. New York, NY: Inc., Springer-Verlag; 2003:46-68.
2002	Mow VC, Guo XE. Mechano-electrochemical properties of articular cartilage: their inhomogeneities and anisotropies. Annu Rev Biomed Eng. 2002;4:175-209.
1987	Frank EH, Grodzinsky AJ. Cartilage electromechanics, I: electrokinetic transduction and the effects of electrolyte pH and ionic strength. J Biomech. 1987;20(6):615-627.
1987	Frank EH, Grodzinsky AJ. Cartilage electromechanics, II: a continuum model of cartilage electrokinetics and correlation with experiments. J Biomech. 1987;20(6):629-639.
1981	Grodzinsky AJ, Roth V, Myers E, Grossman WD, Mow VC. The significance of electromechanical and osmotic forces in the nonequilibrium swelling behavior of articular cartilage in tension. J Biomech Eng. November 1981;103(4):221-231.
2000	Lai WM, Mow VC, Sun DD, Ateshian GA. On the electric potentials inside a charged soft hydrated biological tissue: streaming potential versus diffusion potential. J Biomech Eng. August 2000;122(4):336-346.
2000	Soltz MA, Ateshian GA. A conewise linear elasticity mixture model for the analysis of tension-compression nonlinearity in articular cartilage. J Biomech Eng. December 2000;122(6):576-586.
1980	Roth V, Mow VC. The intrinsic tensile behavior of the matrix of bovine articular cartilage and its variation with age. J Bone Joint Surg. October 1980;62A(7):1102-1117.
1981	Lee RC, Frank EH, Grodzinsky AJ, Roylance DK. Oscillatory compressional behavior of articular cartilage and its associated electromechanical properties. J Biomech Eng. November 1981;103(2):280-292.
1987	Frank EH, Grodzinsky AJ, Koob TJ, Eyre DR. Streaming potentials: a sensitive index of enzymatic degradation in articular cartilage. J Orthop Res. 1987;5(4):497-508.
1996	Sah RL, Trippel SB, Grodzinsky AJ. Differential effects of serum, insulin-like growth factor-I, and fibroblast growth factor-2 on the maintenance of cartilage physical properties during long-term culture. J Orthop Res. January 1996;14(1):44-52.
1980	Mow VC, Lai WM. Recent developments in synovial joint biomechanics. SIAM Rev. 1980;22(3):275-317.
2022	McCreery KP. Multiscale Biophysical Signaling Regulates Tissue Morphogenesis and Degeneration [PhD thesis]. University of Colorado; 2022.
1994	Gu W. A Study of Mechano-Electrokinetic Properties of Charged-Hydrated-Soft Tissues and Biomechanics of Articular Cartilage [PhD thesis]. Columbia University; 1994.
2000	Soltz MA. Investigation of a Boundary Friction Model for Articular Cartilage: Effects of Interstitial Fluid Pressurization and Surface Topography [PhD thesis]. Columbia University; 2000.
2001	Wang C. Digital Video Microscopy-Based Determination of Cartilage Inhomogeneity, Anisotropy and Tension -Compression Nonlinearity: Implications on Chondrocyte Environment [PhD thesis]. Columbia University; 2001.
2002	Sun D. Theoretical and Experimental Investigations of the Mechano-Electrochemical Properties of Articular Cartilage, a Charged -Hydrated -Soft, Biological Tissue [PhD thesis]. Columbia University; 2002.
2007	Likhitpanichkul M. The Cell-Matrix Mechano-Electrochemical Interactions in Articular Cartilage: Experiment and Triphasic Model [PhD thesis]. Columbia University; 2007.
2007	Lu X. Indentation Analysis of Articular Cartilage Using the Triphasic Mixture Theory [PhD thesis]. Columbia University; 2007.
2010	Degala S. Fluid Flow Regulates Articular Chondrocyte Mechanotransduction Pathways in 3D Culture [PhD thesis]. Ithaca, NY: Cornell University; May 2010.
2004	Yao H. Physical Signals and Solute Transport in Cartilaginous Tissues [PhD thesis]. University of Miami; August 2004.
2011	Yuan T-Y. Innovative Methods to Determine Material Properties of Cartilaginous Tissues and Application for Tissue Engineering [PhD thesis]. University of Miami; August 2011.
1983	Eisenberg SR. Nonequilibrium Electromechanical Interactions in Cartilage: Swelling and Electrokinetics Cambridge, MA: Massachusetts Institute of Technology; February 1983.
1987	Frank EH. Electromechanics of Normal and Degenerated Cartilage: Poroelastic Behavior and Electrokinetic Mechanisms [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; May 1987.
1988	MacGinitie LA. Electrical and Thermal Modulation of Protein Synthesis in Cartilage: A Model for Field Effects on Biological Tissues [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; January 1988.
1996	Berkenblit SI. Spatial Localization of Cartilage Degradation Using Electromechanical Surface Spectroscopy With Variable Wavelength and Frequency [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; June 1996.
1999	Treppo S. Physical Diagnostics of Cartilage Degeneration [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; February 1999.
2009	Lee B. Time-Dependent Mechanical Behavior of Newly Developing Matrix of Bovine Primary Chondrocytes and Bone Marrow Stromal Cells Using Atomic Force Microscopy [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; September 2009.
2015	Zignego DL. In Vitro and in Vivo Systems Mechanobiology of Osteoarthritic Chondrocytes [PhD thesis]. Bozeman, MT: Montana State University; July 2015.
2017	Mailhiot SE. Diffusion and Diffusive Exchange Are Sensitive to the Structure of Cartilage as Measured by Nuclear Magnetic Resonance [PhD thesis]. Bozeman, MT: Montana State University; July 2017.
2005	Rundell SA. Investigation of the Acute Injury Response of Articular Cartilage in Vitro and in Vivo: Analysis of Various Therapeutic Treatments [Master's thesis]. East Lansing, MI: Michigan State University; 2005.
2003	Willett TL. The Depth- and Strain-Dependent Electro-Mechanical Properties of Porcine Articular Cartilage [Master's thesis]. Queen's University; May 2003.
2007	June RK II. Polymer Dynamics as a Mechanism of Cartilage Flow-Independent Viscoelasticity [PhD thesis]. Davis, University of California; December 2007.
2009	Mejia KL. The Effect of Long-Term Storage on the Relaxation Properties of Articular Cartilage [Master's thesis]. Davis, University of California; 2009.
2010	Anderson MJ. Effects of Glycation on Dynamic Mechanical Properties and Penetration of Articular Cartilage [Master's thesis]. Davis, University of California; 2010.
1997	Chen AC. Electromechanical Properties of Normal Cartilage and Biomechanical Regulation of Transplanted Chondrocytes: Implications for Articular Cartilage Tissue Engineering [PhD thesis]. San Diego (UCSD), University of California; 1997.