Compressive properties of cortical bone:​ mineral-organic interfacial bonding

Walsh, W. R.<sup>1</sup>; Guzelsu, N.<sup>2</sup>

Affiliations

¹Biomechanics Laboratory, Department of Orthopaedlcs, Brown University School of Medicine, Rhode /s/and Hospital, 593 Eddy Street, Providence, RI 02903, USA

²University of Medicine and Dentistry, SOM Biomechanics & Rutgers University Biomedical Engineering, 675 Hoes Lane, Piscataway, NJ 08854, USA

Abstract and keywords

Bone tissue is an anisotropic non-homogeneous composite material composed of inorganic, bone mineral fibres (hydroxyapatite) embedded in an organic matrix (type I collagen and non-collagenous proteins). Factors contributing to the overall mechanical behaviour include constituent volume fraction, mechanical properties, orientation and interfacial bonding interactions. Interfacial bonding between the mineral and organic constituents is based, in part, on electrostatic interactions between negatively charged organic domains and the positively charged mineral surface. Phosphate and fluoride ions have been demonstrated to alter mineral-organic interactions, thereby influencing the mechanical properties of bone in tension. The present study explores the effects of phosphate and fluoride ions on the compressive properties of cortical bone.

Keywords: Bone; mineral; mechanical properties; interfacial bonding

Links

DOI: 10.1016/0142-9612(94)90263-1

PubMed: 8011860

WoS: A1994MU95500008

History

Received: 1992-12-24

Accepted: 1993-06-20

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