Strain rate and mineral content in fracture models of bone

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Currey, J. D.¹

Strain rate and mineral content in fracture models of bone

J Orthop Res. January 1988;6(1):32-38

©1988 Orthopaedic Research Society

Affiliations

¹Department of Biology, University of York, York, England
Abstract and keywords

I reanalysed data from my previous work to determine the extent to which a model for the loading‐rate dependence of the fracture of cortical bone, put forward by Carter and Caler, fits this independently derived data set. In particular, the extent to which the generality of the model is vitiated by its ignoring the effect of mineralisation on strength was tested. The model was rather strongly corroborated. In addition, the reanalysed data show that yield strain is strongly strain‐rate dependent, but that Young's modulus is rather unvarying over physiological strain rates. The implication of this for hypotheses concerning fracture of bone are discussed.

Keywords: Mechanical properties; Loading rate; Mineralization; Modeling
Links

DOI: 10.1002/jor.1100060105

PubMed: 3334737

WoS: A1988L307200004

Cited Works (10)

Year	Entry
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1975	Currey JD. The effects of strain rate, reconstruction and mineral content on some mechanical properties of bovine bone. J Biomech. 1975;8(1):81-86.
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Cited By (29)

Year	Entry
2002	Currey JD. Bones: Structure and Mechanics. Princeton, NJ: Princeton University Press; 2002.
2012	Forman JL, del Pozo de Dios E, Symeonidis I, Duart J, Kerrigan JR, Salzar RS, Balasubramanian S, Segui‐Gomez M, Kent RW. Fracture tolerance related to skeletal development and aging throughout life: 3‐point bending of human femurs. In: Proceedings of the 2012 International IRCOBI Conference on the Biomechanics of Injury. September 12-14, 2012; Dublin, Ireland.524-539.
1994	Walsh WR, Guzelsu N. Compressive properties of cortical bone: mineral-organic interfacial bonding. Biomaterials. January 1994;15(2):137-145.
1989	Schaffler MB, Radin EL, Burr DB. Mechanical and morphological effects of strain rate on fatigue of compact bone. Bone. 1989;10(3):207-214.
2000	Fyhrie DP, Vashishth D. Bone stiffness predicts strength similarly for human vertebral cancellous bone in compression and for cortical bone in tension. Bone. February 2000;26(2):169-173.
2001	Hernandez CJ, Beaupré GS, Keller TS, Carter DR. The influence of bone volume fraction and ash fraction on bone strength and modulus. Bone. July 2001;29(1):74-78.
1989	Currey JD. Strain rate dependence of the mechanical properties of reindeer antler and the cumulative damage model of bone fracture. J Biomech. 1989;22(5):469-475.
1994	Currey JD, Brear K, Zioupos P. Dependence of mechanical properties on fibre angle in narwhal tusk, a highly oriented biological composite. J Biomech. July 1994;27(7):885-897.
1996	Zioupos P, Wang XT, Currey JD. Experimental and theoretical quantification of the development of damage in fatigue tests of bone and antler. J Biomech. August 1996;29(8):989-1002.
2001	Yeni YN, Fyhrie DP. Finite element calculated uniaxial apparent stiffness is a consistent predictor of uniaxial apparent strength in human vertebral cancellous bone tested with different boundary conditions. J Biomech. December 2001;34(12):1649-1654.
2003	Yeni YN, Fyhrie DP. A rate-dependent microcrack-bridging model that can explain the strain rate dependency of cortical bone apparent yield strength. J Biomech. September 2003;36(9):1343-1353.
2004	Bourne BC, van der Meulen MCH. Finite element models predict cancellous apparent modulus when tissue modulus is scaled from specimen CT-attenuation. J Biomech. May 2004;37(5):613-621.
1995	Courtney AC, Wachtel EF, Myers ER, Hayes WC. Age-related reductions in the strength of the femur tested in a fall-loading configuration. J Bone Joint Surg. March 1995;77A(3):387-395.
2023	Vahidi G, Moody M, Welhaven HD, Davidson L, Rezaee T, Behzad R, Karim L, Roggenbeck BA, Walk ST, Martin SA, June RK, Heveran CM. Germ-free C57BL/6 mice have increased bone mass and altered matrix properties but not decreased bone fracture resistance. J Bone Miner Res. August 2023;38(8):1154-1174.
2001	Zioupos P, Currey JD, Casinos A. Tensile fatigue in bone: are cycles-, or time to failure, or both, important? J Theo Biol. June 7, 2001;210(3):389-399.
2009	Fritsch A, Hellmich C, Dormieux L. Ductile sliding between mineral crystals followed by rupture of collagen crosslinks: experimentally supported micromechanical explanation of bone strength. J Theo Biol. September 21, 2009;260(2):230-252.
2012	Russell NA, Pelletier MH, Bruce WJ, Walsh WR. The effect of gamma irradiation on the anisotropy of bovine cortical bone. Med Eng Phys. October 2012;34(8):1117-1122.
2008	Sharir A, Barak MM, Shahar R. Whole bone mechanics and mechanical testing. Vet J. July 2008;177(1):8-17.
1989	Fondrk MT. An Experimental and Analytical Investigation Into the Nonlinear Constitutive Equations of Cortical Bone [PhD thesis]. Cleveland, OH: Case Western Reserve University; May 1989.
1996	Kotzar GM. Non-Invasive Estimation of Fracture Callus Properties Using a Six Degree-of-Freedom Loadcell Cleveland, OH: Case Western Reserve University; May 1996.
1990	Simske SJ. Development of Model Osteoporosis in Mice: Alleviation by Electromagnetics and Alternative Treatments [PhD thesis]. University of Colorado; July 1990.
2003	Winwood K. An Experimental Investigation Into the Effects of Cyclic Fatigue on Ageing Human Cortical Bone [PhD thesis]. Cranfield University; September 2003.
1994	Courtney AC. Mechanical Properties of the Proximal Femur: Changes With Age [PhD thesis]. Cambridge, MA: Harvard University; May 1994.
2011	Ebacher V. Experimental Study of Deformation and Microcracking in Human Cortical Bone [PhD thesis]. Vancouver, BC: University of British Columbia; May 2011.
2002	Beardsley CL. Development of Quantitative Measures for Bone Comminution Severity [PhD thesis]. University of Iowa; May 2002.
2019	Martig S. Compressive Fatigue Life and Micromorphology of Equine Metacarpal Subchondral Bone [PhD thesis]. University of Melbourne; June 2019.
2022	Martel DR. Contributors to Proximal Femur Fracture Force: Multiscale Considerations of Rate, Toughness, and Bone Composition [PhD thesis]. University of Waterloo; 2022.
2001	Brown CU. Time-Dependent Circumferential Deformation of Cortical Bone Subjected to Internal Radial Loading [PhD thesis]. West Virginia University; 2001.
1993	Sedman AJ. Mechanical Failure and Antler: The Accumulation of Bone of Damage [PhD thesis]. York, UK: University of York; September 1993.