Normal and pathological remodeling of human trabecular bone:​ three dimensional reconstruction of the remodeling sequence in normals and in metabolic bone disease

Eriksen, E. F.

Year	Entry
1990	Simmons DJ, Grynpas MD. Mechanisms of bone formation in vivo. In: Hall BK, ed. Bone. Volume 1: The Osteoblast and Osteocyte. Caldwell, NJ: Inc., The Telford Press; 1990:193-302.
1990	Parfitt AM. Bone-forming cells in clinical conditions. In: Hall BK, ed. Bone. Volume 1: The Osteoblast and Osteocyte. Caldwell, NJ: Inc., The Telford Press; 1990:351-429.
2009	Andersen TL, Sondergaard TE, Skorzynska KE, Dagnaes-Hansen F, Plesner TL, Hauge EM, Plesner T, Delaisse J-M. A physical mechanism for coupling bone resorption and formation in adult human bone. Am J Pathol. January 2009;174(1):239-247.
2013	Andersen TL, Abdelgawad ME, Kristensen HB, Hauge EM, Rolighed L, Bollerslev J, Kjærsgaard-Andersen P, Delaisse J-M. Understanding coupling between bone resorption and formation: are reversal cells the missing link? Am J Pathol. July 2013;183(1):235-246.
2014	Andersen TL, Hauge EM, Rolighed L, Bollerslev J, Kjærsgaard-Andersen P, Delaisse J-M. Correlation between absence of bone remodeling compartment canopies, reversal phase arrest, and deficient bone formation in post-menopausal osteoporosis. Am J Pathol. April 2014;184(4):1142-1151.
1990	Frost HM. Skeletal structural adaptations to mechanical usage (SATMU), II: redefining Wolff's Law: the remodeling problem. Anat Rec. April 1990;226(4):414-422.
2003	Frost HM. Bone's mechanostat: a 2003 update. Anat Rec. 2003;275A(2):1081-1101.
1994	Frost HM. Wolff's law and bone's structural adaptations to mechanical usage: an overview for clinicians. Angle Orthod. June 1994;64(3):175-188.
2020	Sims NA, Martin TJ. Osteoclasts provide coupling signals to osteoblast lineage cells through multiple mechanisms. Annu Rev Physiol. February 10, 2020;82:507-529.
1991	Parfitt AM, Foldes J. The ambiguity of interstitial bone thickness: a new approach to the mechanism of trabecular thinning. Bone. 1991;12(2):119-122.
1992	Steiniche T, Eriksen EF, Kudsk H, Mosekilde L, Melsen F. Reconstruction of the formative site in trabecular bone by a new, quick, and easy method. Bone. 1992;13(2):147-152.
1993	Parfitt AM. Morphometry of bone resorption: introduction and overview. Bone. ;14(3):435-441.
2000	Bell KL, Loveridge N, Jordan GR, Power J, Constant CR, Reeve J. A novel mechanism for induction of increased cortical porosity in cases of intracapsular hip fracture. Bone. August 2000;27(2):297-304.
2002	Eriksen E, Melsen F, Sod E, Barton I, Chines A. Effects of long-term risedronate on bone quality and bone turnover in women with postmenopausal osteoporosis. Bone. November 2002;31(5):620-625.
2018	Andreasen CM, Delaisse J-M, van der Eerden BCJ, van Leeuwen JPTM, Ding M, Andersen TL. Understanding age-induced cortical porosity in women: is a negative BMU balance in quiescent osteons a major contributor? Bone. December 2018;117:70-82.
2020	Delaisse J-M, Andersen TL, Kristensen HB, Jensen PR, Andreasen CM, Søe K. Re-thinking the bone remodeling cycle mechanism and the origin of bone loss. Bone. December 2020;141:115628.
2021	Jensen PR, Andersen TL, Chavassieux P, Roux J-P, Delaisse J-M. Bisphosphonates impair the onset of bone formation at remodeling sites. Bone. April 2021;145:115850.
2021	Li Y, Tseng W-J, de Bakker CMJ, Zhao H, Chung R, Liu XS. Peak trabecular bone microstructure predicts rate of estrogen-deficiency-induced bone loss in rats. Bone. April 2021;145:115862.
2014	Sims NA, Martin TJ. Coupling the activities of bone formation and resorption: a multitude of signals within the basic multicellular unit. BoneKEy Rep. January 2014;3:481.
1991	Compston JE, Croucher PI. Histomorphometric assessment of trabecular bone remodelling in osteoporosis. Bone Miner. August 1, 1991;14(2):91-102.
1993	Yamaguchi K, Croucher PI, Compston JE. Comparison between the lengths of individual osteoid seams and resorption cavities in human iliac crest cancellous bone. Bone Miner. October 1993;23(1):27-33.
2020	Lerebours C, Weinkamer R, Roschger A, Buenzli PR. Mineral density differences between femoral cortical bone and trabecular bone are not explained by turnover rate alone. Bone Rep. December 1, 2020;13:100731.
1989	Frost HM. Transient-steady state phenomena in microdamage physiology: a proposed algorithm for lamellar bone. Calcif Tiss Int. June 1989;44(6):367-381.
2003	Dufresne TE, Chmielewski PA, Manhart MD, Johnson TD, Borah B. Risedronate preserves bone architecture in early postmenopausal women in 1 year as measured by three-dimensional microcomputed tomography. Calcif Tiss Int. November 2003;73(5):423-432.
2008	Clarke B. Normal bone anatomy and physiology. Clin J Am Soc Nephrol. November 2008;3(suppl 3):S131-S139.
1987	Parfitt AM. Bone remodeling and bone loss: understanding the pathophysiology of osteoporosis. Clin Obstet Gynecol. December 1987;30(4):789-811.
1993	Dempster DW, Cosman F, Parisien M, Shen V, Lindsay R. Anabolic actions of parathyroid hormone on bone. Endocr Rev. December 1993;14(6):690-709.
1997	Feik SA, Thomas CDL, Clement JG. Age‐related changes in cortical porosity of the midshaft of the human femur. J Anat. October 1997;191(3):407-416.
2001	Hazelwood SJ, Martin RB, Rashid MM, Rodrigo JJ. A mechanistic model for internal bone remodeling exhibits different dynamic responses in disuse and overload. J Biomech. March 2001;34(3):299-308.
2006	McNamara LM, Van der Linden JC, Weinans H, Prendergast PJ. Stress-concentrating effect of resorption lacunae in trabecular bone. J Biomech. 2006;39(4):734-741.
2020	Ascenzi M-G, Zonca A, Keyak JH. Effect of cortical bone micro-structure in fragility fracture patients on lamellar stress. J Biomech. February 13, 2020;100:109596.
1987	Parfitt AM, Drezner MK, Glorieux FH, Kanis JA, Malluche H, Meunier PJ, Ott SM, Recker RR. Bone histomorphometry: standardization of nomenclature, symbols, and units: report of the ASBMR histomorphometry nomenclature committee. J Bone Miner Res. December 1987;2(6):595-610.
1990	Eriksen EF, Hodgson SF, Eastell R, Cedel SL, O'Fallon WM, Riggs BL. Cancellous bone remodeling in type I (postmenopausal) osteoporosis: quantitative assessment of rates of formation, resorption, and bone loss at tissue and cellular levels. J Bone Miner Res. April 1990;5(4):311-319.
1990	Foldes J, Shih M-S, Parfitt AM. Frequency distributions of tetracycline-based measurements: implications for the interpretation of bone formation indices in the absence of double-labeled surfaces. J Bone Miner Res. October 1990;5(10):1063-1067.
1996	Parfitt AM, Mundy GR, Roodman GD, Hughes DE, Boyce BF. A new model for the regulation of bone resorption, with particular reference to the effects of bisphosphonates. J Bone Miner Res. February 1996;11(2):150-159.
2001	van der Linden JC, Homminga J, Verhaar JAN, Weinans H. Mechanical consequences of bone loss in cancellous bone. J Bone Miner Res. March 2001;16(3):457-465.
2003	Jiang Y, Zhao JJ, Mitlak BH, Wang O, Genant HK, Eriksen EF. Recombinant human parathyroid hormone (1–34) [teriparatide] improves both cortical and cancellous bone structure. J Bone Miner Res. November 2003;18(11):1932-1941.
2006	Ma YL, Zeng Q, Donley DW, Ste‐Marie L, Gallagher JC, Dalsky GP, Marcus R, Eriksen EF. Teriparatide increases bone formation in modeling and remodeling osteons and enhances IGF‐II immunoreactivity in postmenopausal women with osteoporosis. J Bone Miner Res. June 2006;21(6):855-864.
2007	Compston JE, Vedi S, Kaptoge S, Seeman E. Bone remodeling rate and remodeling balance are not co-regulated in adulthood: implications for the use of activation frequency as an index of remodeling rate. J Bone Miner Res. July 2007;22(7):1031-1036.
2008	Recker RR, Delmas PD, Halse J, Reid IR, Boonen S, García-Hernandez PA, Supronik J, Lewiecki EM, Ochoa L, Miller P, Hu H, Mesenbrink P, Hartl F, Gasser J, Eriksen EF. Effects of intravenous zoledronic acid once yearly on bone remodeling and bone structure. J Bone Miner Res. January 2008;23(1):6-16.
2013	Dempster DW, Compston JE, Drezner MK, Glorieux FH, Kanis JA, Malluche H, Meunier PJ, Ott SM, Recker RR, Parfitt AM. Standardized nomenclature, symbols, and units for bone histomorphometry: a 2012 update of the report of the ASBMR Histomorphometry Nomenclature Committee. J Bone Miner Res. January 2013;28(1):2-17.
2017	Lassen NE, Andersen TL, Pløen GG, Søe K, Hauge EM, Harving S, Eschen GET, Delaisse J-M. Coupling of bone resorption and formation in real time: new knowledge gained from human Haversian BMUs. J Bone Miner Res. July 2017;32(7):1395-1405.
2022	Eriksen EF, Chapurlat R, Boyce RW, Shi Y, Brown JP, Horlait S, Betah D, Libanati C, Chavassieux P. Modeling-based bone formation after 2 months of romosozumab treatment: results from the FRAME clinical trial. J Bone Miner Res. January 2022;37(1):36-40.
2023	Weivoda MM, Bradley EW. Macrophages and bone remodeling. J Bone Miner Res. March 2023;38(3):359-369.
1994	Parfitt AM. Osteonal and hemi‐osteonal remodeling: the spatial and temporal framework for signal traffic in adult human bone. J Cell Biochem. July 1994;55(3):273-286.
2011	Hartmann MA, Dunlop JWC, Bréchet YJM, Fratzl P, Weinkamer R. Trabecular bone remodelling simulated by a stochastic exchange of discrete bone packets from the surface. J Mech Behav Biomed Mater. August 2011;4(6):879-887.
2019	Compston JE, McClung MR, Leslie WD. Osteoporosis. Lancet. January 26, 2019;393(10169):364-376.
2010	Eriksen EF. Cellular mechanisms of bone remodeling. Rev Endocr Metab Disord. December 2010;11(4):219-227.
2016	Langdahl B, Ferrari S, Dempster DW. Bone modeling and remodeling: potential as therapeutic targets for the treatment of osteoporosis. Ther Adv Musculoskel Dis. December 2016;8(6):225-235.
2000	Mosekilde L. Age-related changes in bone mass, structure, and strength: effects of loading. Z Rheumatol. February 2000;59(suppl 1):I1-I9.
2017	Saers JPP. Ontogeny and Functional Adaptation of Trabecular Bone in the Human Foot [PhD thesis]. Cambridge, UK: University of Cambridge; July 2017.
2015	Goff M. The Role of Micro and Ultra-Structure in Microdamage Accumulation in Cancellous Bone [PhD thesis]. Ithaca, NY: Cornell University; August 2015.
2020	Fox MC. The Biomechanical Consequences of Body Size Differences in Humans [PhD thesis]. University of Illinois at Urbana-Champaign; 2020.
1997	Qin Y-X. Fluid Flow, Matrix Strain and Loading Frequency as Interdependent Control Parameters in Skeletal Adaptation [PhD thesis]. Stony Brook, NY: State University of New York at Stony Brook; May 1997.
2008	Mulvihill BMC. Computational Investigation Into the Mechanoregulation of Osteoporosis [PhD thesis]. Trinity College Dublin; December 2008.
2005	Ruimerman R. Modeling and Remodeling in Bone Tissue [PhD thesis]. Eindhoven University of Technology; 2005.
2006	Rouhi G. Theoretical Aspects of Bone Remodeling and Resorption Processes [PhD thesis]. Calgary, AB: University of Calgary; March 2006.
2004	Castillo AB. The Female Ferret (Mustela Putorius Furo) as an in Vivo Model for Skeletal Research [PhD thesis]. Davis, University of California; 2004.
2021	Cunningham HC. Bone Adaptation to Disuse in Aging Rodents: Age-Related Differences in Response to Mechanical Unloading and Subsequent Reloading [PhD thesis]. Davis, University of California; 2021.
1993	McCubbrey DA. The Macroscopic Architectural Properties of Vertebral Trabecular Bone and Their Relation to Whole Vertebral Failure Loads [PhD thesis]. University of Michigan; 1993.
2017	de Bakker CMJ. Structural Adaptations of the Maternal Skeleton in Response to Reproduction and Lactation [PhD thesis]. Philadelphia, PA: University of Pennsylvania; 2017.
2021	Li Y. Adaptation of Maternal Skeletal Mechano-Responsiveness, Osteocyte Microenvironment, and Bone Marrow Adipocytes in Response to Reproduction and Lactation [PhD thesis]. Philadelphia, PA: University of Pennsylvania; 2021.
2022	Sales EdS. The Spatio-Temporal Behavior of Basic Multicellular Units in a PTH-Induced Cortical Bone Remodeling Rabbit Model [Master's thesis]. University of Saskatchewan; August 2022.
2019	Kress BJ. Synthesis of Novel Small Molecule PPARδ Agonists for Controlling Mesenchymal Stem Cell Osteogenesis [PhD thesis]. Toledo, OH: University of Toledo; August 2019.

Year	Entry
1983	Melsen F, Mosekilde L, Kragstrup J. Metabolic bone diseases as evaluated by bone histomorphometry. In: Recker RR, ed. Bone Histomorphometry: Techniques and Interpretation. Boca Raton, FL: Inc., CRC Press; 1983:265-284.
1979	Parfitt AM. Quantum concept of bone remodeling and turnover: implications for the pathogenesis of osteoporosis. Calcif Tiss Int. 1979;28(1):1-5.
1976	Parfitt AM. The actions of parathyroid hormone on bone: relation to bone remodeling and turnover, calcium homeostasis, and metabolic bone disease: part I of IV parts: mechanisms of calcium transfer between blood and bone and their cellular basis: morphological and kinetic approaches to bone turnover. Metabolism. July 1976;25(7):809-844.
1981	Kragstrup J, Melsen F, Mosekilde L. Effects of thyroid hormone(s) on mean wall thickness of trabecular bone packets. Metab Bone Dis Rel Res. 1981;3(3):181-184.
1977	Recker RR, Saville PD, Heaney RP. Effect of estrogens and calcium carbonate on bone loss in postmenopausal women. Ann Intern Med. December 1977;87(6):649-655.
1964	Frost HM. Mathematical Elements of Lamellar Bone Remodelling. Springfield, IL: Charles C. Thomas; 1964.
1969	Frost HM. Tetracycline-based histological analysis of bone remodeling. Calcif Tiss Res. 1969;3(1):211-237.
1963	Sedlin ED, Frost HM, Villanueva AR. Variations in cross-section area of rib cortex with age. J Gerontol. 1963;18(1):9-13.
1976	Parfitt AM. The actions of parathyroid hormone on bone: relation to bone remodeling and turnover, calcium homeostasis, and metabolic bone diseases: part II of IV parts: PTH and bone cells: bone turnover and plasma calcium regulation. Metabolism. August 1976;25(8):909-955.
1973	Meunier P, Courpron P, Edouard C, Bernard J, Bringuier J, Vignon G. Physiological senile involution and pathological rarefaction of bone: quantitative and comparative histological data. Clin Endocrinol Metab. July 1973;2(2):239-256.
1977	Whitehouse WJ. Cancellous bone in the anterior part of the iliac crest. Calcif Tiss Res. December 1977;23(1):67-76.
1969	Wakamatsu E, Sissons HA. The cancellous bone of the iliac crest. Calcif Tiss Res. December 1969;4(1):147-161.
1983	Frost HM. Bone histomorphometry: analysis of trabecular bone dynamics. In: Recker RR, ed. Bone Histomorphometry: Techniques and Interpretation. Boca Raton, FL: Inc., CRC Press; 1983:109-131.
1982	Riggs BL, Seeman E, Hodgson SF, Taves DR, O'Fallon WM. Effect of the fluoride/calcium regimen on vertebral fracture occurrence in postmenopausal osteoporosis: comparison with conventional therapy. NEJM. February 25, 1982;306(8):446-450.
1982	Parfitt AM. The coupling of bone formation to bone resorption: a critical analysis of the concept and of its relevance to the pathogenesis of osteoporosis. Metab Bone Dis Rel Res. 1982;4(1):1-6.
1985	Wronski TJ, Lowry PL, Walsh CC, Ignaszewski LA. Skeletal alterations in ovariectomized rats. Calcif Tiss Int. May 1985;37(3):324-328.
1984	Parfitt AM. Age-related structural changes in trabecular and cortical bone: cellular mechanisms and biomechanical consequences. Calcif Tiss Int. 1984;36(suppl 1):S123-S128.
1983	Parfitt AM. Stereologic basis of bone histomorphometry: theory of quantitative micorscopy and reconstruction of the third dimension. In: Recker RR, ed. Bone Histomorphometry: Techniques and Interpretation. Boca Raton, FL: Inc., CRC Press; 1983:53-87.
1983	Parfitt AM. The physiologic and clinical significance of bone histomorphometric data. In: Recker RR, ed. Bone Histomorphometry: Techniques and Interpretation. Boca Raton, FL: Inc., CRC Press; 1983:143-223.
1978	Melsen F, Melsen B, Mosekilde L, Bergmann S. Histomorphometric analysis of normal bone from the iliac crest. Acta Pathol Microbiol Scand. July 1978;86A(1-6):70-81.
1978	Heaney RP, Recker RR, Saville PD. Menopausal changes in bone remodeling. J Lab Clin Med. December 1978;92(6):964-970.
1984	Eriksen EF, Melsen F, Mosekilde L. Reconstruction of the resorptive site in iliac trabecular bone: a kinetic model for bone resorption in 20 normal individuals. Metab Bone Dis Rel Res. 1984;5(5):235-242.
1985	Eriksen EF, Mosekilde L, Melsen F. Trabecular bone resorption depth decreases with age: differences between normal males and females. Bone. 1985;6(3):141-146.
1978	Lips P, Courpron P, Meunier PJ. Mean wall thickness of trabecular bone packets in the human iliac crest: changes with age. Calcif Tiss Res. 1978;26(1):13-17.
1983	Kragstrup J, Melsen F, Mosekilde L. Thickness of bone formed at remodeling sites in normal human iliac trabecular bone: variations with age and sex. Metab Bone Dis Rel Res. 1983–1984;5(1):17-21.
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