Structural and Material Changes in Osteoporosis: Their Impact on the Mechanical Environment of the Osteocyte

Year	Entry
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2000	Ciarelli TE, Fyhrie DP, Schaffler MB, Goldstein SA. Variations in three‐dimensional cancellous bone architecture of the proximal femur in female hip fractures and in controls. J Bone Miner Res. 2000;15(1):32-40.
1991	Hollister SJ, Fyhrie DP, Jepsen KJ, Goldstein SA. Application of homogenization theory to the study of trabecular bone mechanics. J Biomech. 1991;24(9):825-839.
1993	Grynpas M. Age and disease-related changes in the mineral of bone. Calcif Tiss Int. February 1993;53(suppl 1):S57-S64.
1981	Riggs BL, Wahner HW, Dunn WL, Mazess RB, Offord KP, Melton LJ III. Differential changes in bone mineral density of the appendicular and axial skeleton with aging: relationship to spinal osteoporosis. J Clin Invest. February 1981;67(2):328-335.
1994	Keyak JH, Lee IY, Skinner HB. Correlations between orthogonal mechanical properties and density of trabecular bone: use of different densitometric measures. J Biomed Mater Res. November 1994;A28(11):1329-1336.
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1998	Ciarelli TE. Architectural and Material Contributions to Fracture of the Spine and Proximal Femur [PhD thesis]. University of Michigan; 1998.
2000	Verborgt O, Gibson GJ, Schaffler MB. Loss of osteocyte integrity in association with microdamage and bone remodeling after fatigue in vivo. J Bone Miner Res. January 2000;15(1):60-67.
1998	Zysset PK, Goulet RW, Hollister SJ. A global relationship between trabecular bone morphology and homogenized elastic properties. J Biomech Eng. October 1998;120(5):640-646.
1989	Kuhn JL, Goldstein SA, Choi K, London M, Feldkamp LA, Matthews LS. Comparison of the trabecular and cortical tissue moduli from human iliac crests. J Orthop Res. November 1989;7(6):876-884.
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1994	Fyhrie DP, Schaffler MB. Failure mechanisms in human vertebral cancellous bone. Bone. 1994;15(1):105-109.
2000	Dempster DW. The contribution of trabecular architecture to cancellous bone quality. J Bone Miner Res. January 2000;15(1):20-23.
1993	Boyce TM, Bloebaum RD. Cortical aging differences and fracture implications for the human femoral neck. Bone. September–October 1993;14(5):769-778.
1993	Skedros JG, Bloebaum RD, Bachus KN, Boyce TM. The meaning of graylevels in backscattered electron images of bone. J Biomed Mater Res. January 1993;7(1):47-56.
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1997	Bloebaum RD, Skedros JG, Vajda EG, Bachus KN, Constantz BR. Determining mineral content variations in bone using backscattered electron imaging. Bone. May 1997;20(5):485-490.
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1996	Aoubiza B, Crolet JM, Meunier A. On the mechanical characterization of compact bone structure using the homogenization theory. J Biomech. December 1996;29(12):1539-1547.
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1994	Zeng Y, Cowin SC, Weinbaum S. A fiber matrix model for fluid flow and streaming potentials in the canaliculi of an osteon. Ann Biomed Eng. May–June 1994;22(3):280-292.
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1997	Wachtel EF, Keaveny TM. Dependence of trabecular damage on mechanical strain. J Orthop Res. September 1997;15(5):781-787.
1998	Boyde A, Compston JE, Reeve J, Bell KL, Noble BS, Jones SJ, Loveridge N. Effect of estrogen suppression on the mineralization density of iliac crest biopsies in young women as assessed by backscattered electron imaging. Bone. March 1998;22(3):241-250.
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Year	Entry
2002	Homminga J, McCreadie BR, Ciarelli TE, Weinans H, Goldstein SA, Huiskes R. Cancellous bone mechanical properties from normals and patients with hip fractures differ on the structure level, not on the bone hard tissue level. Bone. May 2002;30(5):759-764.
2004	Homminga J, Van-Rietbergen B, Lochmüller EM, Weinans H, Eckstein F, Huiskes R. The osteoporotic vertebral structure is well adapted to the loads of daily life, but not to infrequent "error" loads. Bone. March 2004;34(3):510-516.
2003	Homminga J, McCreadie BR, Weinans H, Huiskes R. The dependence of the elastic properties of osteoporotic cancellous bone on volume fraction and fabric. J Biomech. October 2003;36(10):1461-1467.
2004	McCreadie BR, Hollister SJ, Schaffler MB, Goldstein SA. Osteocyte lacuna size and shape in women with and without osteoporotic fracture. J Biomech. April 2004;37(4):563-572.
2007	Rath Bonivtch A, Bonewald LF, Nicolella DP. Tissue strain amplification at the osteocyte lacuna: a microstructural finite element analysis. J Biomech. 2007;40(10):2199-2206.
2009	Rath AL. The Effects of Strain and Perilacunar Environment on the Mechanotransduction of Osteocytes [PhD thesis]. Winston-Salem, NC: Wake Forest University; May 2009.