Evidence for two distinct syndromes of involutional osteoporosis

Riggs, B. Lawrence; Melton, III, L. Joseph

Affiliations

¹Mayo Clinic and Mayo Foundation, Rochester, Minnesota

Links

DOI: 10.1016/0002-9343(83)90860-4

PubMed: 6650542

WoS: A1983RT79200001

Cited Works (4)

Year	Entry
1982	Riggs BL, Wahner HW, Seeman E, Offord KP, Dunn WL, Mazess RB, Johnson KA, Melton LJ III. Changes in bone mineral density of the proximal femur and spine with aging: differences between the postmenopausal and senile osteoporosis syndromes. J Clin Invest. October 1982;70(4):716-723.
1980	Lindsay R, Hart DM, Forrest C, Baird C. Prevention of spinal osteoporosis in oophorectomised women. Lancet. November 29, 1980;2(8205):1151-1154.
1978	Lips P, Courpron P, Meunier PJ. Mean wall thickness of trabecular bone packets in the human iliac crest: changes with age. Calcif Tiss Res. 1978;26(1):13-17.
1982	Mazess RB. On aging bone loss. Clin Orthop Relat Res. May 1982;165:239-252.

Cited By (38)

Year	Entry
1985	Cummings SR, Kelsey JL, Nevitt MC, O'Dowd KJ. Epidemiology of osteoporosis and osteoporotic fractures. Epidemiol Rev. 1985;7:178-208.
1988	Melton LJ III, Chao EYS, Lane J. Biomechanical aspects of fractures. In: Riggs BL, Melton LJ III, eds. Osteoporosis: Etiology, Diagnosis, and Management. New York, NY: Raven Press; 1988:111-131.
1988	Melton LJ III. Epidemiology of fractures. In: Riggs BL, Melton LJ III, eds. Osteoporosis: Etiology, Diagnosis, and Management. New York, NY: Raven Press; 1988:133-154.
1988	Melton LJ III, Riggs BL. Clinical spectrum. In: Riggs BL, Melton LJ III, eds. Osteoporosis: Etiology, Diagnosis, and Management. New York, NY: Raven Press; 1988:155-179.
1988	Genant HK, Volger JB, Block JE. Radiology of osteoporosis. In: Riggs BL, Melton LJ III, eds. Osteoporosis: Etiology, Diagnosis, and Management. New York, NY: Raven Press; 1988:181-220.
1988	Meunier PJ. Assessment of bone turnover by histomorphometry in osteoporosis. In: Riggs BL, Melton LJ III, eds. Osteoporosis: Etiology, Diagnosis, and Management. New York, NY: Raven Press; 1988:317-332.
1988	Eastell R, Heath H III, Kumar R, Riggs BL. Hormonal factors: PTH, vitamin D, and calcitonin. In: Riggs BL, Melton LJ III, eds. Osteoporosis: Etiology, Diagnosis, and Management. New York, NY: Raven Press; 1988:373-388.
1988	Lane JM, Cornell CN, Healey JH. Orthopaedic consequences of osteoporosis. In: Riggs BL, Melton LJ III, eds. Osteoporosis: Etiology, Diagnosis, and Management. New York, NY: Raven Press; 1988:433-455.
1997	Mori S, Harruff R, Ambrosius W, Burr DB. Trabecular bone volume and microdamage accumulation in the femoral heads of women with and without femoral neck fractures. Bone. December 1997;21(6):521-526.
2000	Jordan GR, Loveridge N, Bell KL, Power J, Rushton N, Reeve J. Spatial clustering of remodeling osteons in the femoral neck cortex: a cause of weakness in hip fracture? Bone. March 2000;26(3):305-313.
1990	Mazess RB. Fracture risk: a role for compact bone. Calcif Tiss Int. October 1990;47(4):191-193.
1993	Guy JA, Shea M, Peter CP, Morrissey R, Hayes WC. Continuous alendronate treatment throughout growth, maturation, and aging in the rat results in increases in bone mass and mechanical properties. Calcif Tiss Int. October 1993;53(4):283-288.
2000	Manolagas SC. Birth and death of bone cells: basic regulatory mechanisms and implications for the pathogenesis and treatment of osteoporosis. Endocr Rev. April 2000;21(2):115-137.
2002	Riggs BL, Khosla S, Melton LJ III. Sex steroids and the construction and conservation of the adult skeleton. Endocr Rev. June 2002;23(3):279-302.
1993	Nevitt MC, Cummings SR; Study of Osteoporofic Fractures Research Group. Type of fall and risk of hip and wrist fractures: the study of osteoporotic fractures. J Am Geriatr Soc. November 1993;41(11):1226-1234.
1996	Garnero P, Sornay‐Rendu E, Chapuy M, Delmas PD. Increased bone turnover in late postmenopausal women is a major determinant of osteoporosis. J Bone Miner Res. 1996;11(3):337-349.
1998	Riggs BL, Khosla S, Melton LJ III. A unitary model for involutional osteoporosis: estrogen deficiency causes both type I and type II osteoporosis in postmenopausal women and contributes to bone loss in aging men. J Bone Miner Res. May 1998;13(5):763-773.
1999	Black DM, Arden NK, Palermo L, Pearson J, Cummings SR; Study of Osteoporotic Fractures Research Group. Prevalent vertebral deformities predict hip fractures and new vertebral deformities but not wrist fractures. J Bone Miner Res. May 1999;14(5):821-828.
2000	McCreadie BR, Goldstein SA. Biomechanics of fracture: is bone mineral density sufficient to assess risk? J Bone Miner Res. December 2000;15(12):2305-2308.
2020	Wong RHX, Zaw JJT, Xian CJ, Howe PRC. Regular supplementation with resveratrol improves bone mineral density in postmenopausal women: a randomized, placebo‐controlled trial. J Bone Miner Res. November 2020;35(11):2121-2131.
2022	Whittier DE, Samelson EJ, Hannan MT, Burt LA, Hanley DA, Biver E, Szulc P, Sornay-Rendu E, Merle B, Chapurlat R, Lespessailles E, Wong AKO, Goltzman D, Khosla S, Ferrari S, Bouxsein ML, Kiel DP, Boyd SK. Bone microarchitecture phenotypes identified in older adults are associated with different levels of osteoporotic fracture risk. J Bone Miner Res. March 2022;37(3):428-439.
1986	Riggs BL, Wahner HW, Melton LJ III, Richelson LS, Judd HL, Offord KP. Rates of bone loss in the appendicular and axial skeletons of women: evidence of substantial vertebral bone loss before menopause. J Clin Invest. May 1986;77(5):1487-1491.
1989	Cummings SR, Nevitt MC. A hypothesis: the causes of hip fractures. J Gerontol Med Sci. September 1989;44(5):M107-M111.
2002	Seeman E. Pathogenesis of bone fragility in women and men. Lancet. May 25, 2002;359(9320):1841-1850.
1986	Riggs BL, Melton LJ III. Involutional osteoporosis. NEJM. June 26, 1986;314(26):1676-1686.
1995	Lotz JC, Cheal EJ, Hayes WC. Stress distributions within the proximal femur during gait and falls: implications for osteoporotic fracture. Osteoporos Int. July 1995;5(3):252-261.
2010	Lynch ME. Cancellous Bone Adaptation to Non-Invasive Mechanical Loading in the Murine Tibia [PhD thesis]. Ithaca, NY: Cornell University; August 2010.
2005	Buie HR. Use of Finite Element Method Modelling and Rapid Prototyping to Study the Effect of Trabecular Bone Architecture on Apparent Mechanical Properties [Master's thesis]. Queen's University; November 2005.
2005	George WT. Multiaxial Fracture Characteristics of Aging Human Bone [PhD thesis]. Troy, NY: Rensselaer Polytechnic Institute; April 2005.
2008	Mulvihill BMC. Computational Investigation Into the Mechanoregulation of Osteoporosis [PhD thesis]. Trinity College Dublin; December 2008.
2005	Ruimerman R. Modeling and Remodeling in Bone Tissue [PhD thesis]. Eindhoven, The Netherlands: Technische Universiteit Eindhoven; 2005.
2021	Whittier DEW. The Assessment of Fragility Fracture Risk Using HR-PQCT as a Novel Tool for Diagnosis of Osteoporosis [PhD thesis]. Calgary, AB: University of Calgary; August 2021.
2020	Pei S. Osteocyte Mechanosensing: Interstitial Fluid Flow, Cellular Response, and Turnover of Pericellular Matrix [PhD thesis]. University of Delaware; 2020.
1993	McCubbrey DA. The Macroscopic Architectural Properties of Vertebral Trabecular Bone and Their Relation to Whole Vertebral Failure Loads [PhD thesis]. University of Michigan; 1993.
1998	Ciarelli TE. Architectural and Material Contributions to Fracture of the Spine and Proximal Femur [PhD thesis]. University of Michigan; 1998.
2000	McCreadie BR. Structural and Material Changes in Osteoporosis: Their Impact on the Mechanical Environment of the Osteocyte [PhD thesis]. University of Michigan; 2000.
2011	Wolfram U. Mechanical Multiscale Characterisation of Vertebral Trabecular Bone for the Prediction of Vertebral Fracture Risk [PhD thesis]. University of Ulm; 2011.
2009	Potter RS. Age Effects on the Material and Mechanical Properties of Bone At the Osteocyte Lacuna [Master's thesis]. San Antionio, TX: University of Texas at San Antonio; December 2009.