Structure, Function, and Adaptation of Compact Bone

Year	Entry
2007	Cowin SC, Doty SB. Bone tissue. In: Tissue Mechanics. Boca Raton, FL: Springer; 2007:341-384.
2007	Cowin SC, Doty SB. Bone tissue adaptation. In: Tissue Mechanics. Boca Raton, FL: Springer; 2007:385-424.
1996	van Rietbergen B. Mechanical Behavior and Adaptation of Trabecular Bone in Relation to Bone Morphology [PhD thesis]. Nijmegen, Netherlands: Catholic University of Nijmegen; 1996.
2011	Wang R, Gupta HS. Deformation and fracture mechanisms of bone and nacre. Ann Rev Mater Res. August 2011;41:41-73.
1991	Weinans HH. Mechanically Induced Bone Adaptations Around Orthopaedic Implants [PhD thesis]. Nijmegen, The Netherlands: Katholieke Universiteit te Nijmegen; 1991.
2001	Jee WSS. Integrated bone tissue physiology: anatomy and physiology. In: Cowin SC, ed. Bone Mechanics Handbook. 2nd ed. Boca Raton, FL: CRC Press; 2001:1-1–1-68.
2001	Turner CH, Burr DB. Experimental techniques for bone mechanics. In: Cowin SC, ed. Bone Mechanics Handbook. 2nd ed. Boca Raton, FL: CRC Press; 2001:7-1–7-35.
2001	Fritton SP, Rubin CT. Dense bone tissue as a molecular composite. In: Cowin SC, ed. Bone Mechanics Handbook. 2nd ed. Boca Raton, FL: CRC Press; 2001:8-1–8-41.
2001	Guo XE. Mechanical properties of cortical and cancellous bone tissue. In: Cowin SC, ed. Bone Mechanics Handbook. 2nd ed. Boca Raton, FL: CRC Press; 2001:10-1–10-23.
2001	Kaufman JJ, Siffert RS. Noninvasive measurement of bone integrity. In: Cowin SC, ed. Bone Mechanics Handbook. 2nd ed. Boca Raton, FL: CRC Press; 2001:34-1–34-25.
2025	Skedros JG. Biomechanical foundations of histological analysis in limb bones: the crucial role of load-complexity categorization and collagen fiber orientation analysis when interpreting bone adaptation. In: Stout SD, Crowder C, eds. Bone Histology: A Biological Anthropological Perspective. 2nd ed. Boca Raton, FL: CRC Press; 2025:150-224.
2025	Pfeiffer S, Pinto D. Histological analyses of human bone from archaeological contexts. In: Stout SD, Crowder C, eds. Bone Histology: A Biological Anthropological Perspective. 2nd ed. Boca Raton, FL: CRC Press; 2025:343-364.
2011	Rantalainen T, Kłodowski A. Estimating lower limb skeletal loading. In: Klika V, ed. Theoretical Biomechanics. InTech; 2011:243-266.
2002	Currey JD. Bones: Structure and Mechanics. Princeton, NJ: Princeton University Press; 2002.
1990	Currey JD. Function and form of bone. In: Mow VC, Ratcliffe A, Woo SL-Y, eds. Biomechanics of Diarthrodial Joints. Vol 2. New York, NY: Springer-Verlag; 1990:3-30.
1998	Martin RB, Burr DB, Sharkey NA. Skeletal Tissue Mechanics. New York, NY: Springer-Verlag; 1998.
2003	Cormier JM, Stitzel JD, Duma SM, Matsuoka F. Microstructural analysis of osteon orientation in human rib cortical bone. In: Proceedings of the 31st International Workshop on Human Subjects for Biomechanical Research. October 23, 2003; San Diego, CA.1-7.
2004	Kennedy EA, Hurst WJ, Stitzel JD, Cormier JM, Hansen GA, Smith EP, Duma SM. Lateral and posterior dynamic bending of the mid-shaft femur: fracture risk curves for the adult population. Stapp Car Crash J. 2004;48:27-51. SAE 2004-22-0002.
2014	Reznikov N, Shahar R, Weiner S. Bone hierarchical structure in three dimensions. Acta Biomater. September 2014;10(8):3815-3826.
2009	Chen P-Y, Stokes AG, McKittrick J. Comparison of the structure and mechanical properties of bovine femur bone and antler of the North American elk (Cervus elaphus canadensis). Acta Biomater. February 2009;5(2):693-706.
2009	Ebacher V, Wang R. A unique microcracking process associated with the inelastic deformation of Haversian bone. Adv Funct Mater. January 9, 2009;19(1):57-66.
2005	Skedros JG, Holmes JL, Vajda EG, Bloebaum AD. Cement lines of secondary osteons in human bone are not mineral‐deficient: new data in a historical perspective. Anat Rec. September 2005;286A(1):781-803.
1994	Frost HM. Wolff's law and bone's structural adaptations to mechanical usage: an overview for clinicians. Angle Orthod. June 1994;64(3):175-188.
2000	Fyhrie DP, Hoshaw SJ, Hamid MS, Hou FJ. Shear stress distribution in the trabeculae of human vertebral bone. Ann Biomed Eng. October 2000;28(10):1194-1199.
1998	Weiner S, Wagner HD. The material bone: structure-mechanical function relations. Ann Rev Mater Sci. August 1998;28:271-298.
2010	Launey ME, Buehler MJ, Ritchie RO. On the mechanistic origins of toughness in bone. Ann Rev Mater Sci. 2010;40:25-53.
2009	Zimmermann EA, Launey ME, Barth HD, Ritchie RO. Mixed-mode fracture of human cortical bone. Biomaterials. October 2009;30(29):5877.
1989	Burr DB, Schaffler MB, Yang KH, Lukoschek M, Sivaneri N, Blaha JD, Radin EL. Skeletal change in response to altered strain environments: is woven bone a response to elevated strain? Bone. 1989;10(3):223-233.
1990	Schaffler MB, Radin EL, Burr DB. Long-term fatigue behavior of compact bone at low strain magnitude and rate. Bone. 1990;11(5):321-326.
1993	Boyce TM, Bloebaum RD. Cortical aging differences and fracture implications for the human femoral neck. Bone. September–October 1993;14(5):769-778.
1994	Fyhrie DP, Schaffler MB. Failure mechanisms in human vertebral cancellous bone. Bone. 1994;15(1):105-109.
1994	Crofts RD, Boyce TM, Bloebaum RD. Aging changes in osteon mineralization in the human femoral neck. Bone. March–April 1994;15(2):147-152.
1994	Heřt J, Fiala P, Petrtýl M. Osteon orientation of the diaphysis of the long bones in man. Bone. May–June 1994;15(3):269-277.
1995	Forwood MR, Turner CH. Skeletal adaptations to mechanical usage: results from tibial loading studies in rats. Bone. October 1995;17(4)(suppl):197S-205S.
1997	Bloebaum RD, Skedros JG, Vajda EG, Bachus KN, Constantz BR. Determining mineral content variations in bone using backscattered electron imaging. Bone. May 1997;20(5):485-490.
1997	Yeni YN, Brown CU, Wang Z, Norman TL. The influence of bone morphology on fracture toughness of the human femur and tibia. Bone. November 1997;21(4):453-459.
1998	Zioupos P, Currey JD. Changes in the stiffness, strength, and toughness of human cortical bone with age. Bone. January 1998;22(1):57-66.
2000	Yeni YN, Norman TL. Fracture toughness of human femoral neck: effect of microstructure, composition, and age. Bone. May 2000;26(5):499-504.
2001	Robling AG, Duijvelaar KM, Geevers JV, Ohashi N, Turner CH. Modulation of appositional and longitudinal bone growth in the rat ulna by applied static and dynamic force. Bone. August 2001;29(2):105-113.
2002	Burr DB. Targeted and nontargeted remodeling. Bone. January 2002;30(1):2-4.
2002	Yeni YN, Fyhrie DP. Fatigue damage-fracture mechanics interaction in cortical bone. Bone. March 2002;30(3):509-514.
2002	Burr DB, Robling AG, Turner CH. Effects of biomechanical stress on bones in animals. Bone. May 2002;30(5):781-786.
2006	Diab T, Condo KW, Burr DB, Vashishth D. Age-related change in the damage morphology of human cortical bone and its role in bone fragility. Bone. March 2006;38(3):427-431.
2007	Diab T, Vashishth D. Morphology, localization and accumulation of in vivo microdamage in human cortical bone. Bone. March 2007;40(3):612-618.
2013	Reznikov N, Almany-Magal R, Shahar R, Weiner S. Three-dimensional imaging of collagen fibril organization in rat circumferential lamellar bone using a dual beam electron microscope reveals ordered and disordered sub-lamellar structures. Bone. February 2013;52(2):676-683.
2014	Reznikov N, Shahar R, Weiner S. Three-dimensional structure of human lamellar bone: the presence of two different materials and new insights into the hierarchical organization. Bone. February 2014;59:93-104.
2015	Tang T, Ebacher V, Cripton P, Guy P, McKay H, Wang R. Shear deformation and fracture of human cortical bone. Bone. February 2015;71:25-35.
2019	Burr DB. Stress concentrations and bone microdamage: John Currey's contributions to understanding the initiation and arrest of cracks in bone. Bone. October 2019;127:517-525.
2022	Bonicelli A, Kranioti EF, Xhemali B, Arnold E, Zioupos P. Assessing bone maturity: compositional and mechanical properties of rib cortical bone at different ages. Bone. February 2022;155:116265.
1992	Frost HM, Jee WSS. On the rat model of human osteopenias and osteoporoses. Bone Miner. September 1992;18(3):227-236.
1992	Frost HM. Perspectives: bone's mechanical usage windows. Bone Miner. December 1992;19(3):257-271.
1993	Martin B. Aging and strength of bone as a structural material. Calcif Tiss Int. February 1993;53(suppl 1):S34-S40.
1998	Wohl GR, Loehrke L, Watkins BA, Zernicke RF. Effects of high-fat diet on mature bone mineral content, structure, and mechanical properties. Calcif Tiss Int. July 1998;63(1):74-79.
2001	Li J, Mashiba T, Burr DB. Bisphosphonate treatment suppresses not only stochastic remodeling but also the targeted repair of microdamage. Calcif Tiss Int. November 2001;69(5):281-286.
2012	Abdel-Wahab AA, Maligno AR, Silberschmidt VV. Micro-scale modelling of bovine cortical bone fracture: analysis of crack propagation and microstructure using X-FEM. Comp Mater Sci. February 2012;52(1):128-135.
2004	Doblaré M, García JM, Gomez MJ. Modelling bone tissue fracture and healing: a review. Eng Fract Mech. September 2004;71(13-14):1809-1840.
1997	Guo XE, Goldstein SA. Is trabecular bone tissue different from cortical bone tissue? Forma. 1997;12(3-4):185-196.
2020	Zhou J, Cui Z, Sevostianov I. Effect of saturation on the elastic properties and anisotropy of cortical bone. Int J Eng Sci. October 2020;155:103362.
2006	Zioupos P, Kaffy C, Currey JD. Tissue heterogeneity, composite architecture and fractal dimension effects in the fracture of ageing human bone. Int J Fract. June 2006;139(3-4):407-424.
2000	Lee TC, Staines A, Taylor D. Bone adaptation to load: microdamage as a stimulus for bone remodelling. J Anat. December 2000;201(6):437-446.
2003	Lee TC, Mohsin S, Taylor D, Parkesh R, Gunnlaugsson T, O'Brien FJ, Giehl M, Gowin W. Detecting microdamage in bone. J Anat. August 2003;203(2):161-172.
2006	Mohsin S, O'Brien FJ, Lee TC. Osteonal crack barriers in ovine compact bone. J Anat. January 2006;208(1):81-89.
2012	Skedros JG, Knight AN, Farnsworth RW, Bloebaum RD. Do regional modifications in tissue mineral content and microscopic mineralization heterogeneity adapt trabecular bone tracts for habitual bending? analysis in the context of trabecular architecture of deer calcanei. J Anat. March 2012;220(3):242-255.
2001	Zioupos P. Ageing human bone: factors affecting its biomechanical properties and the role of collagen. J Biomater Appl. January 2001;15(3):187-229.
1991	Martin RB. Determinants of the mechanical properties of bones. J Biomech. 1991;24(suppl 1):79-88.
1992	Hogan HA. Micromechanics modeling of Haversian cortical bone properties. J Biomech. May 1992;25(5):549-556.
1992	Pidaparti RMV, Burr DB. Collagen fiber orientation and geometry effects on the mechanical properties of secondary osteons. J Biomech. August 1992;25(8):869-880.
1994	Hollister SJ, Brennan JM, Kikuchi N. A homogenization sampling procedure for calculating trabecular bone effective stiffness and tissue level stres. J Biomech. 1994;27(4):433-444.
1994	Prendergast P, Taylor D. Prediction of bone adaptation using damage accumulation. J Biomech. August 1994;27(8):1067-1076.
1995	van Rietbergen B, Weinans H, Huiskes R, Odgaard A. A new method to determine trabecular bone elastic properties and loading using micromechanical finite-element models. J Biomech. January 1995;28(1):69-81.
1995	Norman TL, Vashishth D, Burr DB. Fracture toughness of human bone under tension. J Biomech. March 1995;28(3):309-320.
1996	Petrtýl M, Heřt J, Fiala P. Spatial organization of the haversian bone in man. J Biomech. February 1996;29(2):161-169.
1996	Norman TL, Nivargikar SV, Burr DB. Resistance to crack growth in human cortical bone is greater in shear than in tension. J Biomech. August 1996;29(8):1023-1031.
1996	Courtney AC, Hayes WC, Gibson LJ. Age-related differences in post-yield damage in human cortical bone: experiment and model. J Biomech. November 1996;29(11):1463-1471.
1998	Taylor D. Microcrack growth parameters for compact bone deduced from stiffness variations. J Biomech. July 1998;31(7):587-592.
1998	Zioupos P, Casinos A. Cumulative damage and the response of human bone in two-step loading fatigue. J Biomech. September 1998;31(9):825-833.
1998	Taylor D, Lee TC. Measuring the shape and size of microcracks in bone. J Biomech. December 1998;31(12):1177-1180.
1999	Liu D, Weiner S, Wagner HD. Anisotropic mechanical properties of lamellar bone using miniature cantilever bending specimens. J Biomech. July 1999;32(7):647-654.
2000	Sevostianov I, Kachanov M. Impact of the porous microstructure on the overall elastic properties of the osteonal cortical bone. J Biomech. July 2000;33(7):881-888.
2003	Yeni YN, Fyhrie DP. A rate-dependent microcrack-bridging model that can explain the strain rate dependency of cortical bone apparent yield strength. J Biomech. September 2003;36(9):1343-1353.
2003	Qin Y-X, Kaplan T, Saldanha A, Rubin C. Fluid pressure gradients, arising from oscillations in intramedullary pressure, is correlated with the formation of bone and inhibition of intracortical porosity. J Biomech. October 2003;36(10):1427-1437.
2004	Sobelman OS, Gibeling JC, Stover SM, Hazelwood SJ, Yeh OC, Shelton DR, Martin RB. Do microcracks decrease or increase fatigue resistance in cortical bone? J Biomech. September 2004;37(9):1295-1303.
2006	Gibson VA, Stover SM, Gibeling JC, Hazelwood SJ, Martin RB. Osteonal effects on elastic modulus and fatigue life in equine bone. J Biomech. 2006;39(2):217-225.
2006	McNamara LM, Van der Linden JC, Weinans H, Prendergast PJ. Stress-concentrating effect of resorption lacunae in trabecular bone. J Biomech. 2006;39(4):734-741.
2007	McNamara LM, Prendergast PJ. Bone remodelling algorithms incorporating both strain and microdamage stimuli. J Biomech. 2007;40(6):1381-1391.
2007	Ural A, Vashishth D. Anisotropy of age-related toughness loss in human cortical bone: a finite element study. J Biomech. 2007;40(7):1606-1614.
2012	Al Nazer R, Lanovaz J, Kawalilak C, Johnston JD, Kontulainen S. Direct in vivo strain measurements in human bone: a systematic literature review. J Biomech. January 3, 2012;45(1):27-40.
1996	Prendergast PJ, Huiskes R. Microdamage and osteocyte-lacuna strain in bone: a microstructural finite element analysis. J Biomech Eng. May 1996;118(2):240-246.
1998	Guo XE, Liang LC, Goldstein SA. Micromechanics of osteonal cortical bone fracture. J Biomech Eng. February 1998;120(1):112-117.
1998	Zhang D, Weinbaum S, Cowin SC. Estimates of the peak pressures in bone pore water. J Biomech Eng. December 1998;120(6):697-703.
2000	Butler DL, Goldstein SA, Guilak F. Functional tissue engineering: the role of biomechanics. J Biomech Eng. December 2000;122(6):570-575.
2000	Phelps JB, Hubbard GB, Wang X, Agrawal CM. Microstructural heterogeneity and the fracture toughness of bone. J Biomed Mater Res. September 15, 2000;51(4):735-741.
1999	Roy ME, Rho J-Y, Tsui TY, Evans ND, Pharr GM. Mechanical and morphological variation of the human lumbar vertebral cortical and trabecular bone. J Biomed Mater Res. February 1999;A44(2):191-197.
1999	Zioupos P, Currey JD, Hamer AJ. The role of collagen in the declining mechanical properties of aging human cortical bone. J Biomed Mater Res. May 1999;A45(2):108-116.
1995	Courtney AC, Wachtel EF, Myers ER, Hayes WC. Age-related reductions in the strength of the femur tested in a fall-loading configuration. J Bone Joint Surg. March 1995;77A(3):387-395.
1995	Buckwalter JA, Glimcher MJ, Cooper RR, Recker R. Bone biology, I: structure, blood supply, cells, matrix, and mineralization. J Bone Joint Surg. August 1995;77A(8):1256-1275.
1995	Rubin CT, Gross TS, McLeod KJ, Bain SD. Morphologie stages in lamellar bone formation stimulated by a potent mechanical stimulus. J Bone Miner Res. March 1995;10(3):488-495.
1996	Takano Y, Turner CH, Burr DB. Mineral anisotropy in mineralized tissues is similar among species and mineral growth occurs independently of collagen orientation in rats: results from acoustic velocity measurements. J Bone Miner Res. September 1996;11(9):1292-1301.
1997	Burr DB. Muscle strength, bone mass, and age‐related bone loss. J Bone Miner Res. 1997;12(10):1547-1551.
1997	Frost HM. On our age‐related bone loss: insights from a new paradigm. J Bone Miner Res. October 1997;12(10):1539-1546.
2000	Smit TH, Burger EH. Is BMU-coupling a strain-regulated phenomenon? a finite element analysis. J Bone Miner Res. February 2000;12(2):301-307.
2001	Ryder KD, Duncan RL. Parathyroid hormone enhances fluid shear-induced [Ca²⁺]_i signaling in osteoblastic cells through activation of mechanosensitive and voltage-sensitive Ca²⁺ channels. J Bone Miner Res. February 2001;16(2):240-248.
2018	Kersh ME, Martelli S, Zebaze R, Seeman E, Pandy MG. Mechanical loading of the femoral neck in human locomotion. J Bone Miner Res. November 2018;33(11):1999-2006.
1994	Zioupos P, Currey JD. The extent of microcracking and the morphology of microcracks in damaged bone. J Mater Sci. 1994;29(4):978-986.
2001	Parsamian GP, Norman TL. Diffuse damage accumulation in the fracture process zone of human cortical bone specimens and its influence on fracture toughness. J Mater Sci Mater Med. September 2001;12(9):779-783.
2011	Kulin RM, Jiang F, Vecchio KS. Effects of age and loading rate on equine cortical bone failure. J Mech Behav Biomed Mater. January 2011;4(1):57-75.
2021	Du J, Li S, Silberschmidt VV. Remodelling of trabecular bone in human distal tibia: a model based on an in-vivo HR-pQCT study. J Mech Behav Biomed Mater. July 2021;119:104506.
1991	Simmons ED Jr, Pritzker KPH, Grynpas MD. Age‐related changes in the human femoral cortex. J Orthop Res. 1991;9(2):155-167.
1995	Martin B. Mathematical model for repair of fatigue damage and stress fracture in osteonal bone. J Orthop Res. May 1995;13(3):309-316.
1996	Martin RB, Stover SM, Gibson VA, Gibeling JC, Griffin LV. In vitro fatigue behavior of the equine third metacarpus: remodeling and microcrack damage analysis. J Orthop Res. September 1996;14(5):794-801.
1997	Griffin LV, Gibeling JC, Martin RB, Gibson VA, Stover SM. Model of flexural fatigue damage accumulation for cortical bone. J Orthop Res. July 1997;15(4):607-614.
2002	Les CM, Stover SM, Keyak JH, Taylor KT, Kaneps AJ. Stiff and strong compressive properties are associated with brittle post‐yield behavior in equine compact bone material. J Orthop Res. May 2002;20(2):607-614.
2005	O'Brien FJ, Taylor D, Lee TC. The effect of bone microstructure on the initiation and growth of microcracks. J Orthop Res. March 2005;23(2):475-480.
1999	Weiner S, Traub W, Wagner HD. Lamellar bone: structure–function relations. J Struct Biol. June 1999;126(3):241-255.
2010	Zebaze RMD, Ghasem-Zadeh A, Bohte A, Iuliano-Burns S, Mirams M, Price RI, Mackie EJ, Seeman E. Intracortical remodelling and porosity in the distal radius and post-mortem femurs of women: a cross-sectional study. Lancet. May 15, 2010;375(9727):1729-1736.
2005	Dong XN, Zhang X, Guo XE. Interfacial strength of cement lines in human cortical bone. Mech Chem Biosyst. June 2005;2(2):63-8.
2005	Nyman JS, Reyes M, Wang X. Effect of ultrastructural changes on the toughness of bone. Micron. October–December 2005;36(7-8):566-582.
2007	Tai K, Dao M, Suresh S, Palazoglu A, Ortiz C. Nanoscale heterogeneity promotes energy dissipation in bone. Nat Mater. June 2007;6(6):454-462.
2014	Schwiedrzik J, Raghavan R, Bürki A, LeNader V, Wolfram U, Michler J, Zysset P. In situ micropillar compression reveals superior strength and ductility but an absence of damage in lamellar bone. Nat Med. July 2014;13(7):740-747.
2003	Burr D. Microdamage and bone strength. Osteoporos Int. September 2003;14(suppl 5):S67-S72.
1995	Zioupos P, Currey JD, Mirza MS, Barton DC. Experimentally determined microcracking around a circular hole in a flat plate of bone: comparison with predicted stresses. Philos Trans R Soc Lond B Biol Sci. March 29, 1995;347(1322):383-396.
1990	Bonadio J, Saunders TL, Tsai E, Goldstein SA, Morris-Wiman J, Brinkley L, Dolan DF, Altschuler RA, Hawkins JE Jr, Bateman JF, Mascara T, Jaenisch R. Transgenic mouse model of the mild dominant form of osteogenesis imperfecta. Proc Natl Acad Sci USA. September 1990;87(18):7145-7149.
2004	Pearson OM, Lieberman DE. The aging of Wolff's “law”: ontogeny and responses to mechanical loading in cortical bone. Yearb Phys Anthropol. 2004;47:63-99.
2002	Dong X. Micromechanics of Osteonal Cortical Bone [PhD thesis]. Columbia University; 2002.
2018	Chen JTH. Alterations in Bone Tissue Properties With Parathyroid Hormone Treatment [PhD thesis]. Ithaca, NY: Cornell University; May 2018.
2003	Winwood K. An Experimental Investigation Into the Effects of Cyclic Fatigue on Ageing Human Cortical Bone [PhD thesis]. Cranfield University; September 2003.
2008	Ciani C. Characterization of Microporosities and Load-Induced Interstitial Fluid Movement in Normal and Osteopenic Bone [PhD thesis]. New York, NY: The City University of New York; 2008.
2019	Bakr M. Parathyroid Hormone Effect on Facilitating Stress Fracture Repair [PhD thesis]. Brisbane, Australia: Griffith University; July 2019.
1994	Courtney AC. Mechanical Properties of the Proximal Femur: Changes With Age [PhD thesis]. Cambridge, MA: Harvard University; May 1994.
2000	Ryder KD. Parathyroid Hormone Modulates the Response of Osteoblast-Like Cells to Mechanical Stimulation [PhD thesis]. Indianapolis, IN: Indiana University; May 2000.
1995	Heinrich RE. Functional Morphology and Body Size of Early Tertiary Miacoidea (mammalia, Carnivora) [PhD thesis]. Johns Hopkins University; 1995.
1999	Egi N. Functional Morphology of the Limb Bones in Recent Carnivores and Its Application to North American Hyaenodontid Creodonta [PhD thesis]. Johns Hopkins University; 1999.
1997	Heinonen A. Exercise as an Osteogenic Stimulus [PhD thesis]. University of Jyväskylä; 1997.
2002	Kontulainen S. Training, Detraining and Bone: Effect of Exercise on Bone Mass and Structure With Special Reference to Maintenance of the Exercise-Induced Bone Gain [PhD thesis]. University of Jyväskylä; 2002.
2011	Abdel-Wahab AA-GM. Experimental and Numerical Analysis of Deformation and Fracture of Cortical Bone Tissue [PhD thesis]. Loughborough University; August 2011.
2019	Du J. Mechanical Adaptation of Human Trabecular Bone: Experimental and Computational Study [PhD thesis]. Loughborough University; 2019.
2000	Richman CC. In Vitro and in Vivo Studies on Bone Formation [PhD thesis]. Loma Linda University; March 2000.
2005	Offiah A. Optimisation of the Digital Radiographic Imaging of Suspected Non-Accidental Injury [PhD thesis]. London, UK: University of London; March 2005.
2007	Akhtar R. Micromechanical Behaviour of Bone [PhD thesis]. University of Manchester; 2007.
2009	Karakolis T. Mechanical Induction of Bone Formation: Comparison Between Rat and Mouse Forelimb Models [Master's thesis]. Hamilton, ON: McMaster University; December 2009.
1998	Robling AG. Histomorphometric Assessment of Mechanical Loading History from Human Skeletal Remains: The Relation Between Micromorphology and Macromorphology At the Femoral Midshaft [PhD thesis]. University of Missouri; December 1998.
2007	Tai K. Nanomechanics and Ultrastructural Studies of Cortical Bone: Fundamental Insights Regarding Structure-Function, Mineral-Organic Force Mechanics Interactions, and Heterogeneity [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; June 2007.
2020	O’Sullivan LM. Time-Sequence of Biomechanical Adaption in Trabecular Tissue During Estrogen Deficiency [PhD thesis]. National University of Ireland Galway; March 2020.
2012	Sun X. Mechanically Induced Calcium Efflux from Bone Matrix Stimulates Osteoblasts [PhD thesis]. Purdue University; May 2012.
2001	Kim DG. Micromechanical Analysis of Bone At a Bone-Implant Interface [PhD thesis]. Troy, NY: Rensselaer Polytechnic Institute; April 2001.
2006	Diab T. The Role of Damage Morphology in Age-Related Increase in Bone Fragility [PhD thesis]. Troy, NY: Rensselaer Polytechnic Institute; 2006.
2010	Janeiro C. The Effect of Bone Quality on Osteoclastic Bone Resorption [PhD thesis]. Troy, NY: Rensselaer Polytechnic Institute; May 2010.
2000	Kotha SP. A Micromechanical Model to Explain the Mechanical Properties of Bovine Cortical Bone in Tension: In Vitro Fluoride Ion Effects [PhD thesis]. Rutgers University; January 2000.
1994	Levenston ME. Simulation of Functional Adaptation in Trabecular and Cortical Bone [PhD thesis]. Stanford University; September 1994.
1997	Qin Y-X. Fluid Flow, Matrix Strain and Loading Frequency as Interdependent Control Parameters in Skeletal Adaptation [PhD thesis]. Stony Brook, NY: State University of New York at Stony Brook; May 1997.
2000	O’Brien FJ. Microcracks and the Fatigue Behaviour of Compact Bone [PhD thesis]. Trinity College Dublin; October 2000.
2004	McNamara LM. Biomechanical Origins of Osteoporosis [PhD thesis]. Trinity College Dublin; March 2004.
1994	Oden ZM. Computational Prediction of Functional Adaptation in Canine Radii [PhD thesis]. Tulane University; 1994.
1996	Bober MB. The Regulation of Gene Expression by Mechanical Stimulation and Parathyroid Hormone in Bone in Vivo [PhD thesis]. Tulane University; 1996.
2000	Coleman JC. Analysis of in Vivo Bone Strain History During Dynamic Mechanical Loading [PhD thesis]. Tulane University; 2000.
2003	Verborgt O. Osteocyte Apoptosis and Bone Remodeling [PhD thesis]. University of Antwerp; 2003.
2011	Ebacher V. Experimental Study of Deformation and Microcracking in Human Cortical Bone [PhD thesis]. Vancouver, BC: University of British Columbia; May 2011.
2018	Tang T. Fracture Mechanisms and Structural Fragility of Human Femoral Cortical Bone [PhD thesis]. Vancouver, BC: University of British Columbia; April 2018.
1999	Judex S. The Effect of Exercise-Induced Mechanical Stimuli on Cortical Bone [PhD thesis]. Calgary, AB: University of Calgary; 1999.
2001	Boyd SK. Microstructural Bone Adaptation in an Experimental Model of Osteoarthritis [PhD thesis]. Calgary, AB: University of Calgary; January 2001.
2002	Wohl GR. Bone Mechanics in Transplanted Osteochondral Grafts [PhD thesis]. Calgary, AB: University of Calgary; September 2002.
2004	LaMothe JM. Functional Adaptation of Bone [PhD thesis]. Calgary, AB: University of Calgary; September 2004.
2006	Rouhi G. Theoretical Aspects of Bone Remodeling and Resorption Processes [PhD thesis]. Calgary, AB: University of Calgary; March 2006.
2011	Coza A. Effects of Mechanical Vibrations and Compression on Muscle Contractile Properties and Physiology [PhD thesis]. Calgary, AB: University of Calgary; January 2011.
2012	Nishiyama KKS. In Vivo Assessment of Bone Microarchitecture and Estimated Bone Strength [PhD thesis]. Calgary, AB: University of Calgary; October 2012.
2000	Nauman EA. The Analytical Design of a Hybrid Bone Substitute [PhD thesis]. Berkeley, CA: Berkeley, University of California; Spring 2000.
2011	Zimmermann EA. Deformation and Fracture of Human Cortical Bone Across Multiple Length-Scales [PhD thesis]. Berkeley, CA: Berkeley, University of California; F 2011.
1999	Donahue SW. Bone Strain and Microdamage At Stress Fracture Sites in Human Metatarsals [PhD thesis]. Davis, University of California; 1999.
2000	Gibson VA. Fatigue Behavior of Equine Third Metacarpal Bone Tissue [PhD thesis]. Davis, University of California; 2000.
2009	Raison M. On the Quantification of Joint and Muscle Efforts in the Human Body During Motion [PhD thesis]. Université catholique de Louvain; June 23, 2009.
2012	Zephro L. Determining the Timing and Mechanism of Bone Fracture in Bovine Bone [PhD thesis]. Santa Cruz, University of California; June 2012.
2010	Kulin RM. On the Dynamic Behavior of Mineralized Tissues [PhD thesis]. San Diego (UCSD), University of California; 2010.
1996	Rossi SA. The Prediction of Human Cortical Bone Strength Using the Finite-Element Method: A Study of the Flexural and Torsional Behavior of Femoral Shafts With Simulated Metastatic Lesions [PhD thesis]. San Francisco, University of California; 1996.
2011	Majumdar S. Cell Surface ATP Synthase: A Novel Mechanism for ATP Signaling in Osteoblasts [PhD thesis]. University of Delaware; Summer 2011.
2005	Yan J. Elastic-Plastic Fracture Mechanics of Compact Bone [PhD thesis]. University of Florida; 2005.
1996	Adams DJ. Mechanical Factors Initiating Appositional Bone Formation [PhD thesis]. University of Iowa; May 1996.
2023	Fuller LH. Structure-Function Relationships of Bighorn Sheep Horncore Bone and Horn-Horncore Interface Materials for Energy Absorption Applications [PhD thesis]. University of Massachusetts at Amherst; February 2023.
1991	Hollister SJ. Homogenization Analysis of Trabecular Bone and Prediction Ofbone Ingrowth Using Topology Optimization [PhD thesis]. University of Michigan; 1991.
1995	Guldberg RE. Mechanical Adaptation of Trabecular Bone Formation in Vivo [PhD thesis]. University of Michigan; 1995.
1995	Tseng K-F. Investigating the Structure-Function Relationships of Long Bone: An Approach Using Growth Hormone Mouse Models [PhD thesis]. University of Michigan; 1995.
1996	Germiller JA. Influence of Skeletal Muscle on Embryonic Long Bone Development [PhD thesis]. University of Michigan; 1996.
1996	Rouleau JP. The Influence of Cyclic Strain Amplitude and Timing of Mechanical Stimulation on Secondary Fracture Healing [PhD thesis]. University of Michigan; 1996.
2000	Borodkin JL. The Influence of Interface Micromechanics on the Biological Fixation of Porous-Coated Implants [PhD thesis]. University of Michigan; 2000.
2010	Hughes JM. Revisiting Harold Frost's Mechanostat Theory of Bone Functional Adaptation: New Interpretations Based on New Evidence [PhD thesis]. University of Minnesota; December 2010.
2014	Schwiedrzik JJ. Experimental, Theoretical and Numerical Investigation of the Nonlinear Micromechanical Properties of Bone [PhD thesis]. Universität Bern; 2014.
2013	Blaber EA. Stem Cell-Based Tissue Regeneration in Space [PhD thesis]. University of New South Wales; November 2013.
1996	Beck BR. The Relationship of Streaming Potential Magnitude to Strain and Periosteal Modeling [PhD thesis]. Eugene, OR: University of Oregon; December 1996.
2014	Carter Y. Quantitative Imaging of Sex and Age Differences in Human Cortical Bone Osteocyte Lacunae [PhD thesis]. University of Saskatchewan; July 2014.
1993	Boyce TM. Aging Changes Within the Human Femoral Neck Cortex [PhD thesis]. University of Utah; August 1993.
1998	Vajda EG. Age-Related Changes in the Microstructure and Mineralization of the Female Proximal Femur [PhD thesis]. University of Utah; March 1998.
2010	Beckstrom AB. Histologic and Geometric Data Challenge the Assumption of Habitual Superior-Inferior (tension-Compression) Bending Across the Chimpanzee Proximal Femur [Master's thesis]. University of Utah; August 2010.
2013	Eleazer CD. The Interaction of Mechanical Loading and Metabolic Stress on Human Cortical Bone: Testing Anthropological Assumptions Using Cross-Sectional Geometry and Histomorphology [PhD thesis]. Knoxville, University of Tennessee; August 2013.
2014	Reeves NM. Augmenting Functional Adaptation: Does Obesity Have a Systemic Effect on Bone Strength Properties in Humans? [PhD thesis]. Knoxville, University of Tennessee; May 2014.
2002	Stock JT. Climatic and Behavioural Influences on Postcranial Robusticity Among Holocene Foragers [PhD thesis]. University of Toronto; 2002.
2009	Nakade R. Influence of Interfacial Properties and Inhomogeneity on Formation of Microdamage in Bone [Master's thesis]. San Antionio, TX: University of Texas at San Antonio; December 2009.
2021	Fiori CJ-BM. An in Vitro Model of Oxidative Damage in Bovine Cortical Bone to Induce Bone Fragility [Master's thesis]. University of Waterloo; 2021.
2003	Cormier JM. Microstructural and Mechanical Properties of Human Ribs [Master's thesis]. Virginia Polytechnic Institute and State University; April 22, 2003.
2014	Reznikov N. The Adaptation of Mechanical Properties of Lamellar Bone Tissue [PhD thesis]. Weizmann Institute of Science; July 2014.
2022	Luo TD. The Effects of Ascorbic Acid in the Treatment of Radiation-Induced Bone Damage [PhD thesis]. Winston-Salem, NC: Wake Forest University; September 2022.
1997	Iwaniec UT. Effects of Dietary Acidity on Cortical Bone Remodeling: A Histomorphometric Assessment [PhD thesis]. University of Wisconsin – Madison; 1997.
1998	Yeni YN. Fracture Mechanics of Human Cortical Bone: The Relationship of Geometry, Microstructure and Composition With the Fracture of the Tibia, Femoral Shaft and the Femoral Neck [PhD thesis]. West Virginia University; 1998.
2004	Porter DS. Smoking and Dose-Dependent Early Effects of Nicotine on Bone Mechanical Properties and Histology [Master's thesis]. West Virginia University; 2004.
1993	Sedman AJ. Mechanical Failure and Antler: The Accumulation of Bone of Damage [PhD thesis]. York, UK: University of York; September 1993.