Muscle strength, bone mass, and age‐related bone loss

Burr, David B.

Affiliations

¹Departments of Anatomy and Orthopedic Surgery, Indiana University School of Medicine, Biomechanics and Biomaterials Research Center, Indiana University-Purdue University at Indianapolis, Indianapolis, Indiana, U.S.A

Links

DOI: 10.1359/jbmr.1997.12.10.1547

PubMed: 9333114

WoS: A1997XY46700002

History

Online: 1997-10-1

Cited Works (7)

Year	Entry
1989	Martin RB, Burr DB. Structure, Function, and Adaptation of Compact Bone. New York, NY: Raven Press; 1989.
1987	Frost HM. The mechanostat: a proposed pathogenic mechanism of osteoporoses and the bone mass effects of mechanical and nonmechanical agents. Bone Miner. April 1987;2(2):73-85.
1997	Frost HM. On our age‐related bone loss: insights from a new paradigm. J Bone Miner Res. October 1997;12(10):1539-1546.
1991	Rodan GA. Perspectives: mechanical loading, estrogen deficiency, and the coupling of bone formation to bone resorption. J Bone Miner Res. June 1991;6(6):527-530.
1993	Forwood MR, Burr DB. Physical activity and bone mass: exercises in futility? Bone Miner. May 1993;21(2):89-112.
1985	Frost HM. The pathomechanics of osteoporoses. Clin Orthop Relat Res. November 1985;200:198-225.
1986	Frost HM. Intermediary Organization of the Skeleton. Vols. 1-2. Boca Raton, FL: CRC Press; 1986.

Cited By (39)

Year	Entry
2001	Jee WSS. Integrated bone tissue physiology: anatomy and physiology. In: Cowin SC, ed. Bone Mechanics Handbook. 2nd ed. Boca Raton, FL: CRC Press; 2001:1-1–1-68.
2003	Frost HM. Bone's mechanostat: a 2003 update. Anat Rec. 2003;275A(2):1081-1101.
1999	Iwamoto J, Yeh JK, Aloia JF. Differential effect of treadmill exercise on three cancellous bone sites in the young growing rat. Bone. March 1999;24(3):163-169.
2013	Willie BM, Birkhold AI, Razi H, Thiele T, Aido M, Kruck B, Schill A, Checa S, Main RP, Duda GN. Diminished response to in vivo mechanical loading in trabecular and not cortical bone in adulthood of female C57Bl/6 mice coincides with a reduction in deformation to load. Bone. August 2013;55(2):335-346.
2020	Berman AG, Organ JM, Allen MR, Wallace JM. Muscle contraction induces osteogenic levels of cortical bone strain despite muscle weakness in a mouse model of osteogenesis imperfecta. Bone. March 2020;132:115061.
2021	Lee JH, Park J, Kim JH, Choi J-Y, Choi HJ, Ku EJ, Hong AR, Shin CS, Cho NH. Integrative analysis of genetic and clinical risk factors for bone loss in a Korean population. Bone. June 2021;147:115910.
2022	Smith C, Hiam D, Tacey A, Lin X, Woessner MN, Zarekookandeh N, Garnham A, Chubb P, Lewis JR, Sim M, Herrmann M, Duque G, Levinger I. Higher bone remodeling biomarkers are related to a higher muscle function in older adults: effects of acute exercise. Bone. December 2022;165:116545.
2023	Cunningham HC, Orr S, Murugesh DK, Hsia AW, Osipov B, Go L, Wu PH, Wong A, Loots GG, Kazakia GJ, Christiansen BA. Differential bone adaptation to mechanical unloading and reloading in young, old, and osteocyte deficient mice. Bone. February 2023;167:116646.
2005	Thomas CDL, Feik SA, Clement JG. Regional variation of intracortical porosity in the midshaft of the human femur: age and sex differences. J Anat. February 2005;206(2):115-125.
2000	Beck TJ, Looker AC, Ruff CB, Sievanen H, Wahner HW. Structural trends in the aging femoral neck and proximal shaft: analysis of the third national health and nutrition examination survey dual‐energy x‐ray absorptiometry data. J Bone Miner Res. December 2000;15(12):2297-2304.
2001	Beck TJ, Oreskovic TL, Stone KL, Ruff CB, Ensrud K, Nevitt MC, Genant HK, Cummings SR. Structural adaptation to changing skeletal load in the progression toward hip fragility: the study of osteoporotic fractures. J Bone Miner Res. June 2001;16(6):1108-1119.
2020	Higgins S, Sokolowski CM, Vishwanathan M, Schmidt MD, Evans EM, Lewis RD. Sex‐specific muscular mediation of the relationship between physical activity and cortical bone in young adults. J Bone Miner Res. January 2020;35(1):81-91.
2000	Ruff CB. Body size, body shape, and long bone strength in modern humans. J Hum Evol. February 2000;38(2):269-290.
2001	Jee WSS, Yao W. Overview: animal models of osteopenia and osteoporosis. J Musculoskel Neuron Interact. March 2001;1(3):193-207.
2020	Hart NH, Newton RU, Tan2 J, Rantalainen T, Chivers P, Siafarikas A, Nimphius S. Biological basis of bone strength: anatomy, physiology and measurement. J Musculoskel Neuron Interact. September 2020;20(3):347-371.
2020	Turcotte A-F, Kukuljan S, Dalla Via J, Gagnon C, Abbott G, Daly RM. Changes in spinal bone density, back muscle size, and visceral adipose tissue and their interaction following a multi-component exercise program in older men: secondary analysis of an 18-month randomized controlled trial. Osteoporos Int. October 2020;31(10):2025-2035.
2018	Spasic M. Targeting Primary Cilia-Mediated Mechanotransduction to Promote Whole Bone Formation [PhD thesis]. Columbia University; 2018.
2019	Lambert C. A Comparison of the Bone Response to Impact Loading and Resistance Training in Young Adult Women: The OPTIMA-Ex Trial [PhD thesis]. Brisbane, Australia: Griffith University; July 2019.
2019	Myers KB. Are Improvements in Bone and Physical Performance from an 8-Month High-Intensity Exercise Program Maintained in Postmenopausal Women With Low Bone Mass? 3-Year Follow-P of the LIFTMOR Trial [Master's thesis]. Brisbane, Australia: Griffith University; 2019.
2019	Watson S. LIFTMOR: Lifting Intervention for Training Muscle and Osteoporosis Rehabilitation [PhD thesis]. Brisbane, Australia: Griffith University; January 2019.
2007	Auerbach BM. Human Skeletal Variation in the New World During the Holocene: Effects of Climate and Subsistence Across Geography and Time [PhD thesis]. Johns Hopkins University; August 2007.
1998	Ward WE. Steroid-Induced Growth Delay and Bone Abnormalities in Preterm Infants and Piglets During Early Development: The Interaction of Steroids and the GH-IGF-I Axis [PhD thesis]. Hamilton, ON: McMaster University; July 1998.
2012	Druchok C. The Effect of a High-Fat Diet on Bone Strain in Adult Rat Femurs [Master's thesis]. Hamilton, ON: McMaster University; October 2012.
2014	Ellman R. Skeletal Adaptation to Reduced Mechanical Loading [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; September 2014.
2020	Brzezinski ET. Sex Differences in Workload in Medieval Eastern Europe: Patterns of Asymmetry and Biomechanical Adaptation in the Upper Limb At Giecz, Poland [Master's thesis]. The Ohio State University; 2020.
2003	Peterman MM. A Strain Map of the Human Distal Tibia During the Stance Phase of Walking, from Dynamic Cadaver Experiments and Finite Element Analysis Simulations [PhD thesis]. State College, PA: Pennsylvania State University; August 2003.
2009	Bower AL. An Investigation of Trabecular Bone Morphology [PhD thesis]. State College, PA: Pennsylvania State University; December 2009.
2005	Squire ME. Bone’s Response to Unloading, as Defined by Altered Gene Expression, Cellular Activity, and Architecture, is Modulated by Genetics and Gender [PhD thesis]. Stony Brook, NY: Stony Brook University; August 2005.
2016	Sankaran JS. Identification of Genes That Modulate Bone Loss During Mechanical Unloading [PhD thesis]. Stony Brook, NY: Stony Brook University; August 2016.
2005	Ashe MC. Upper Limb Bone Health: Cadaveric, Imaging and Clinical Studies With Special Emphasis on Peripheral Quantitative Computed Tomography [PhD thesis]. Vancouver, BC: University of British Columbia; April 2005.
2006	Macdonald HM. Effectiveness of a School-Based Physical Activity Intervention for Increasing Bone Strength in Children: Action Schools! British Columbia [PhD thesis]. Vancouver, BC: University of British Columbia; July 2006.
2006	Rouhi G. Theoretical Aspects of Bone Remodeling and Resorption Processes [PhD thesis]. Calgary, AB: University of Calgary; March 2006.
2010	Manske SL. Muscle Disuse and Vibration Effects on Bone Morphology [PhD thesis]. Calgary, AB: University of Calgary; December 2010.
2016	Pangka AVS. Biomechanical Measures of the Muscle-Bone Unit in Postmenopausal Females: A Pilot Study [Master's thesis]. Calgary, AB: University of Calgary; August 2016.
2021	Cunningham HC. Bone Adaptation to Disuse in Aging Rodents: Age-Related Differences in Response to Mechanical Unloading and Subsequent Reloading [PhD thesis]. Davis, University of California; 2021.
2014	Gangadharan V. Delineating the Cellular Mechanism of Osteoblast Desensitization to Mechanical Stimulation [PhD thesis]. University of Delaware; 2014.
2010	Joiner DM. The Effect of Age on Bone and Its Response to Mechanical Stimulation [PhD thesis]. University of Michigan; 2010.
2013	Burnett W. Quantitative Computed Tomography Analysis of Patellar Subchondral Bone Density [Master's thesis]. University of Saskatchewan; January 2013.
2014	Reeves NM. Augmenting Functional Adaptation: Does Obesity Have a Systemic Effect on Bone Strength Properties in Humans? [PhD thesis]. Knoxville, University of Tennessee; May 2014.