Bone mineral assay: its relation to the mechanical strength of cancellous bone

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Hvid, I.¹; Jensen, N. C.¹; Bünger, C.¹; Sølund, K.¹; Djurhuus, J. C.¹

Bone mineral assay: its relation to the mechanical strength of cancellous bone

Eng Med. 1985;14(2):79-83

©1985 MEP Ltd.

Affiliations

¹Orthopaedic Hospital and Institute of Experimental Clinical Research, University of Aarhus, Denmark
Abstract

Photon absorptiometric (¹²⁵) bone mineral assay and low strain-rate axial compression tests were carried out on cylindrical cancellous bone specimens from the proximal tibial epiphysis of large, skeletally mature mongrel dogs. Bone mineral assay was reproducible within ±5.0 per cent (99 per cent tolerance limits). Linear regression analysis with the bone mineral concentration as the independent variable showed a strong correlation towards the ultimate strength (r = 0.92) and the yield strength (r = 0.89), somewhat weaker towards the elastic modulus (r = 0.82), the ultimate energy absorption (r = 0.79), and the yield energy absorption (r = 0.73), and insignificant towards the ultimate strain (r = −0.14) and the yield strain (r = −0.18). The power relationships between trabecular bone density and compressive strength and modulus suggested by Carter and Hayes (1977) were not statistically superior to linear relationships in the relatively narrow density range reported here. The quadratic relationship between bone mineral content and energy absorption suggested for cortical bone (Currey, 1969) could not be confirmed for trabecular bone. Linear regression analysis with the elastic modulus as the independent variable showed that the regression coefficients to predict ultimate strength and yield strength are statistically indistinguishable from those found in studies on human material. It is concluded that non-destructive techniques to measure bone density and mineralization may be suitable for clinical bone strength assay.
Links

DOI: 10.1243/EMED_JOUR_1985_014_016_02

PubMed: 4043498

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Cited By (33)

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1991	Edidin AA. Modeling of Bone Material Properties from CT Scans: Considerations in Biomechanical Structural Models [PhD thesis]. Ithaca, NY: Cornell University; May 1991.
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1996	Ford CM. Failure of the Human Proximal Femur: Material and Structural Perspectives [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; September 1996.
2001	Arthur Moore TL. Microdamage Accumulation in Bovine Trabecular Bone [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; June 2001.
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2002	Morgan EF-i. The Dependence on Anatomic Site of Trabecular Bone Structure-Function Relationships [PhD thesis]. Berkeley, CA: Berkeley, University of California; 2002.
1993	Goulet RW. The Quantification of the Structure and Mechanical Properties of Trabecular Bone [PhD thesis]. University of Michigan; 1993.
2008	Burgers TA. Press-Fit Fixation and Viscoelastic Response of a Bone-Implant Interface in the Distal Femur [PhD thesis]. University of Wisconsin – Madison; 2008.
2011	Aiyangar AK. Physical and Computational Modeling of Subsidence of Anterior Interbody Fusion Devices [PhD thesis]. University of Wisconsin – Madison; 2011.