Mechanosensory mechanisms in bone

Cowin, Stephen C.; Moss, Melvin L.

Year	Entry
1991	Goldstein SA, Matthews LS, Kuhn JL, Hollister SJ. Trabecular bone remodeling: an experimental model. J Biomech. 1991;24(suppl 1):135-150.
1990	Brown TD, Pedersen DR, Gray ML, Brand RA, Rubin CT. Toward an identification of mechanical parameters initiating periosteal remodeling: a combined experimental and analytic approach. J Biomech. 1990;23(9):893-905.
1993	Harrigan TP, Hamilton JJ. Bone strain sensation via transmembrane potential changes in surface osteoblasts: loading rate and microstructural implications. J Biomech. February 1993;26(2):183-200.
1987	Salzstein RA, Pollack SR. Electromechanical potentials in cortical bone, II: experimental analysis. J Biomech. 1987;20(3):271-280.
1990	Kufahl RH, Saha S. A theoretical model for stress-generated fluid flow in the canaliculi-lacunae network in bone tissue. J Biomech. 1990;23(2):171-180.
1987	Rubin CT, Lanyon LE. Osteoregulatory nature of mechanical stimuli: function as a determinant for adaptive remodeling in bone. J Orthop Res. 1987;5(2):300-310.
1993	Lanyon LE. Osteocytes, strain detection, bone modeling and remodeling. Calcif Tiss Int. February 1993;53(suppl 1):S102-S107.
1978	Uhthoff HK, Jaworski ZF. Bone loss in response to long-term immobilisation. J Bone Joint Surg. August 1978;60B(3):420-429.
1971	Heřt J, Lišková M, Landa J. Reaction of bone to mechanical stimuli, I: continuous and intermittent loading of tibia in rabbit. Folia Morphol (Praha). August 1971;19(3):290-300.
1995	Cowin SC, Weinbaum S, Zeng Y. A case for bone canaliculi as the anatomical site of strain generated potentials. J Biomech. November 1995;28(11):1281-1297.
1994	Williams JL, Iannotti JP, Ham A, Bleuit J, Chen JH. Effects of fluid shear stress on bone cells. Biorheology. March–April 1994;31(2):163-170.
1892	Wolff J. Das Gesetz der Transformation der Knochen. Berlin: Hirschwald; 1892.
1995	Pitsillides AA, Rawlinson SCF, Suswillo RFL, Bourrin S, Zaman G, Lanyon LE. Mechanical strain‐induced NO production by bone cells: a possible role in adaptive bone (re)modeling? FASEB J. December 1995;9(15):1614-1622.
1969	Frost HM. Tetracycline-based histological analysis of bone remodeling. Calcif Tiss Res. 1969;3(1):211-237.
1988	Montgomery RJ, Sutker BD, Bronk JT, Smith SR, Kelly PJ. Interstitial fluid flow in cortical bone. Microvasc Res. May 1988;35(3):295-307.
1997	Owan I, Burr DB, Turner CH, Qiu J, Tu Y, Onyia JE, Duncan RL. Mechanotransduction in bone: osteoblasts are more responsive to fluid forces than mechanical strain. Am J Physiol Cell Physiol. September 1997;273(3):C810-C815.
1992	Otter MW, Palmieri VR, Wu DD, Seiz KG, MacGinitie LA, Cochran GVB. A comparative analysis of streaming potentials in vivo and in vitro. J Orthop Res. September 1992;10(5):710-719.
1992	Marotti G, Ferretti M, Muglia M, Palumbo C, Palazzini S. A quantitative evaluation of osteoblast-osteocyte relationships on growing endosteal surface of rabbit tibiae. Bone. July–August 1992;13(5):363-368.
2000	Fritton SP, McLeod KJ, Rubin CT. Quantifying the strain history of bone: spatial uniformity and self-similarity of low-magnitude strains. J Biomech. March 2000;33(3):317-325.
1991	Cowin SC, Moss-Salentijn L, Moss ML. Candidates for the mechanosensory system in bone. J Biomech Eng. May 1991;113(2):191-197.
1984	Lanyon LE. Functional strain as a determinant for bone remodeling. Calcif Tiss Int. March 1984;36(suppl 1):S56-S61.
1995	Hung T Clark, Pollack R Solomon, Reilly TM, Brighton T Carl. Real-time calcium response of cultured bone cells to fluid flow. Clin Orthop Relat Res. April 1995;313:256-269.
1977	Piekarski K, Munro M. Transport mechanism operating between blood supply and osteocytes in long bones. Nature. September 1, 1977;270(5623):80-82.
1976	Carter DR, Hayes WC. Bone compressive strength: the influence of density and strain rate. Science. September 10, 1976;194(4270):1174-1176.
1964	Frost HM. The Laws of Bone Structure. Springfield, IL: Charles C. Thomas; 1964.
1993	Wang N, Butler JP, Ingber DE. Mechanotransduction across the cell surface and through the cytoskeleton. Science. May 21, 1993;260(5111):1124-1127.
1998	Zhang D, Weinbaum S, Cowin SC. Estimates of the peak pressures in bone pore water. J Biomech Eng. December 1998;120(6):697-703.
1994	Parfitt AM. Osteonal and hemi‐osteonal remodeling: the spatial and temporal framework for signal traffic in adult human bone. J Cell Biochem. July 1994;55(3):273-286.
1996	Sasaki N, Odajima S. Elongation mechanism of collagen fibrils and force-strain relations of tendon at each level of structural hierarchy. J Biomech. 1996;29(9):1131-1136.
1981	Doty SB. Morphological evidence of gap junctions between bone cells. Calcif Tiss Int. 1981;33(5):509-512.
1994	Aarden EM, Burger EH, Nijweide PJ. Function of osteocytes in bone. J Cell Biochem. July 1994;55(3):287-299.
1990	Scott GC, Korostoff E. Oscillatory and step response electromechanical phenomena in human and bovine bone. J Biomech. 1990;23(2):127-143.
1997	Salter DM, Robb JE, Wright MO. Electrophysiological responses of human bone cells to mechanical stimulation: evidence for specific integrin function in mechanotransduction. J Bone Miner Res. July 1997;12(7):1133-1141.
1976	Cowin SC, Hegedus DH. Bone remodeling, I: theory of adaptive elasticity. J Elast. 1976;6(3):313-326.
1982	Lanyon LE, Goodship AE, Pye CJ, MacFie JH. Mechanically adaptive bone remodelling. J Biomech. 1982;15(3):141-154.
1982	Johnson MW, Chakkalakal DA, Harper RA, Katz JL, Rouhana SW. Fluid flow in bone in vitro. J Biomech. 1982;15(11):881-885.
1994	Zeng Y, Cowin SC, Weinbaum S. A fiber matrix model for fluid flow and streaming potentials in the canaliculi of an osteon. Ann Biomed Eng. May–June 1994;22(3):280-292.
1984	Rubin CT, Lanyon LE. Regulation of bone formation by applied dynamic loads. J Bone Joint Surg. March 1984;66A(3):397-402.
1980	Jaworski ZFG, Liskova-Kiar M, Uhthoff HK. Effect of long-term immobilisation on the pattern of bone loss in older dogs. J Bone Joint Surg. February 1980;62B(1):104-110.
1982	Martin RB, Burr DB. A hypothetical mechanism for the stimulation of osteonal remodelling by fatigue damage. J Biomech. 1982;15(3):137-139.
1986	Fyhrie DP, Carter DR. A unifying principle relating stress to trabecular bone morphology. J Orthop Res. 1986;4(3):304-317.
1984	Pollack SR, Petrov N, Salzstein R, Brankov G, Blagoeva R. An anatomical model for streaming potentials in osteons. J Biomech. 1984;17(8):627-636.
1995	Klein-Nulend J, van der Plas A, Semeins CM, Ajubi NE, Frangos JA, Nijweide PJ, Burger EH. Sensitivity of osteocytes to biomechanical stress in vitro. FASEB J. March 1995;9(5):441-445.
1994	Weinbaum S, Cowin SC, Zeng Y. A model for the excitation of osteocytes by mechanical loading-induced bone fluid shear stresses. J Biomech. March 1994;27(3):339-360.
1999	Wang L, Fritton SP, Cowin SC, Weinbaum S. Fluid pressure relaxation depends upon osteonal microstructure: modeling an oscillatory bending experiment. J Biomech. July 1999;32(7):663-672.
1997	Gross TS, Edwards JL, Mcleod KJ, Rubin CT. Strain gradients correlate with sites of periosteal bone formation. J Bone Miner Res. June 1997;12(6):982-988.
1999	Cowin SC. Bone poroelasticity. J Biomech. March 1999;32(3):217-238.
1995	Klein-Nulend J, Semeins CM, Ajubi NE, Nijweide P, Burger EH. Pulsating fluid flow increases nitric oxide (NO) synthesis by osteocytes but not periosteal fibroblasts - correlation with prostaglandin upregulation. Biochem Biophys Res Commun. December 14, 1995;217(2):640-648.
1987	Huiskes R, Weinans H, Grootenboer HJ, Dalstra M, Fudala B, Slooff TJ. Adaptive bone-remodeling theory applied to prosthetic-design analysis. J Biomech. 1987;20(11-12):1135-1150.
1982	O'Connor JA, Lanyon LE, MacFie H. The influence of strain rate on adaptive bone remodelling. J Biomech. 1982;15(10):767-781.
1987	Salzstein RA, Pollack SR, Mak AFT, Petrov N. Electromechanical potentials in cortical bone, I: a continuum approach. J Biomech. 1987;20(3):261-270.
1997	Zhang D, Cowin SC, Weinbaum S. Electrical signal transmission and gap junction regulation in a bone cell network: a cable model for an osteon. Ann Biomed Eng. March 1997;25(2):357-374.
1990	Reich KM, Gay CV, Frangos JA. Fluid shear stress as a mediator of osteoblast cyclic adenosine monophosphate production. J Cell Physiol. April 1990;143(1):100-103.

Year	Entry
2007	Cowin SC, Doty SB. Bone tissue adaptation. In: Tissue Mechanics. Boca Raton, FL: Springer; 2007:385-424.
2011	Hartmann MA, Dunlop JWC, Bréchet YJM, Fratzl P, Weinkamer R. Trabecular bone remodelling simulated by a stochastic exchange of discrete bone packets from the surface. J Mech Behav Biomed Mater. August 2011;4(6):879-887.
2004	Pearson OM, Lieberman DE. The aging of Wolff's “law”: ontogeny and responses to mechanical loading in cortical bone. Yearb Phys Anthropol. 2004;47:63-99.
2012	Moore E. The Frequency, Aqueous Solution, Stress Amplitude, Temperature (FAST) Machine: A Device Proposed for Accelerated Fatigue Testing of Cortical Bone [Master's thesis]. Cleveland, OH: Case Western Reserve University; August 2012.
2005	Yoon YJ. Estimates of Bone Elastic Constants At Sequential Hierarchical Levels [PhD thesis]. New York, NY: The City University of New York; 2005.
2007	Devlin MJ. Interactions of Estrogen, Strain, and Bone Growth: Implications for Human Skeletal Robusticity [PhD thesis]. Cambridge, MA: Harvard University; September 2007.
2020	Lamarche BA. Morphometric Changes With Age in Human Trabecular Bone Structural Units (BSU) of the Lumbar Spine [Master's thesis]. Sudbury, ON: Laurentian University; 2020.
2012	Druchok C. The Effect of a High-Fat Diet on Bone Strain in Adult Rat Femurs [Master's thesis]. Hamilton, ON: McMaster University; October 2012.
2004	Tovar A. Bone Remodeling as a Hybrid Cellular Automaton Optimization Process [PhD thesis]. University of Notre Dame; December 2004.
2010	Manske SL. Muscle Disuse and Vibration Effects on Bone Morphology [PhD thesis]. Calgary, AB: University of Calgary; December 2010.