Tissue engineering

Langer, Robert; Vacanti, Joseph P.

Year	Entry
1998	Knight MM, Lee DA, Bader DL. The influence of elaborated pericellular matrix on the deformation of isolated articular chondrocytes cultured in agarose. Biochim Biophys Acta. October 21, 1998;1405:67-77.
2000	Hutmacher DW. Scaffolds in tissue engineering bone and cartilage. Biomaterials. December 15, 2000;21(24):2529-2543.
2003	Drury JL, Mooney DJ. Hydrogels for tissue engineering: scaffold design variables and applications. Biomaterials. November 2003;24(24):4337-4351.
2010	Zhu J. Bioactive modification of poly(ethylene glycol) hydrogels for tissue engineering. Biomaterials. June 2010;31(17):4639-4656.
1994	Hillsley MV, Frangos JA. Review: bone tissue engineering: the role of interstitial fluid flow. Biotechnol Bioeng. March 25, 1994;43(7):573-581.
1998	Vunjak-Novakovic G, Obradovic B, Martin I, Bursac PM, Langer R, Freed LE. Dynamic cell seeding of polymer scaffolds for cartilage tissue engineering. Biotechnol Prog. March–April 1998;14(2):193-202.
2003	Sachlos E, Czernuszka JT. Making tissue engineering scaffolds work: review on the application of solid freeform fabrication technology to the production of tissue engineering scaffolds. Eur Cell Mater. 2003;5:29-40.
2009	Boerckel JD, Dupont KM, Kolambkar YM, Lin ASP, Guldberg RE. In vivo model for evaluating the effects of mechanical stimulation on tissue-engineered bone repair. J Biomech Eng. August 2009;131(8):084502.
2020	Yoon JP, Chung SW, Jung JW, Lee Y, Kim K, Park GY, Kim H, Choi J. Is a local administration of parathyroid hormone effective to tendon‐to‐bone healing in a rat rotator cuff repair model? J Orthop Res. January 2020;38(1):82-91.
2004	Salgado AJ, Coutinho OP, Reis RL. Bone tissue engineering: state of the art and future trends. Macromol Biosci. August 9, 2004;4(8):743-765.
2019	Bian T, Zhao K, Meng Q, Tang Y, Jiao H, Luo J. The construction and performance of multi-level hierarchical hydroxyapatite (HA)/collagen composite implant based on biomimetic bone Haversian motif. Mater Des. January 15, 2019;162:60-69.
2005	Hollister SJ. Porous scaffold design for tissue engineering. Nat Mater. July 2005;4(7):518-524.
2010	Estes BT, Diekman BO, Gimble JM, Guilak F. Isolation of adipose-derived stem cells and their induction to a chondrogenic phenotype. Nat Protoc. July 2010;5(7):1294-1311.
2000	Lee KY, Peters MC, Anderson KW, Mooney DJ. Controlled growth factor release from synthetic extracellular matrices. Nature. December 21, 2000;408:998-1000.
1997	Freed LE, Langer R, Martin I, Pellis NR, Vunjak-Novakovic G. Tissue engineering of cartilage in space. Proc Natl Acad Sci USA. December 9, 1997;94(25):13885-13890.
2012	Huey DJ, Hu JC, Athanasiou KA. Unlike bone, cartilage regeneration remains elusive. Science. November 16, 2012;338(6109):917-921.
2001	Yang S, Leong K-F, Du Z, Chua C-K. The design of scaffolds for use in tissue engineering, I: traditional factors. Tissue Eng. December 2001;7(6):679-689.
2002	Yang S, Leong K-F, Du Z, Chua C-K. The design of scaffolds for use in tissue engineering, II: rapid prototyping techniques. Tissue Eng. February 2002;8(1):1-11.
2011	Patel RS. Cell-Based Growth Factor Delivery for in Situ Tissue Regeneration and Repair [PhD thesis]. Brown University; May 2011.
2001	Bursac N. Engineered Cardiac Tissue: A Novel in Vitro Model for Electrophysiological Studies of Cardiac Muscle [PhD thesis]. Boston University; 2001.
2018	Wang Y. Transport of GAG Digesting Enzymes in Engineered Cartilage Tissues [Master's thesis]. Boston University; 2018.
2018	Wang T. Optimization of Delivery of TGF-Beta for Improving Quality of Engineered Articular Cartilage [Master's thesis]. Boston University; 2018.
2022	McCreery KP. Multiscale Biophysical Signaling Regulates Tissue Morphogenesis and Degeneration [PhD thesis]. University of Colorado; 2022.
2018	Pauly HM. Development of a Hierarchical Electrospun Scaffold for Ligament Replacement [PhD thesis]. Colorado State University; 2018.
2007	Wan Q. Fundamental Theoretical and Experimental Studies for Applications Toward Functional Tissue Engineering of Articular Cartilage [PhD thesis]. Columbia University; 2007.
2008	Spalazzi JP. Biomimetic Multi-Phasic Scaffold Design for Orthpaedic Interface Tissue Engineering [PhD thesis]. Columbia University; 2008.
2014	Sampat SR. Optimization of Culture Conditions for Cartilage Tissue Engineering Using Synovium-Derived Stem Cells [PhD thesis]. Columbia University; 2014.
2015	Chuang PJ. Development and Characterization of Ion Encapsulated Liposomes for Vesicle-Mediated Biomineralization [PhD thesis]. Columbia University; 2015.
2016	Cigan AD. Nutrient Channels to Aid the Growth of Articular Surface-Sized Engineered Cartilage Constructs [PhD thesis]. Columbia University; 2016.
2016	Nover AB. Fabrication of Tissue Engineered Osteochondral Allografts for Clinical Translation [PhD thesis]. Columbia University; 2016.
2020	Mosher CZ. Interface Scaffold Design Principles for Integrative Cartilage Regeneration [PhD thesis]. Columbia University; 2020.
2010	Babalola OM. Effects of Physical Stimuli on Extracellular Matrix Assembly by Chondrocytes and Mesenchymal Stem Cells: Experimental and Finite Element Analyses [PhD thesis]. Ithaca, NY: Cornell University; May 2010.
2018	Mojica Santiago JA. Tissue Engineering of Cervical Intervertebral Discs: An in Vitro and in Vivo Pre-Clinical Canine Model of Total Disc Replacement [PhD thesis]. Ithaca, NY: Cornell University; August 2018.
2011	Bian W. Tissue Engineering of a Differentiated Skeletal Muscle Construct With Controllable Structure and Function [PhD thesis]. Duke University; 2011.
2013	Liau B. Role of Non-Myocytes in Engineering of Highly Functional Pluripotent Stem Cell-Derived Cardiac Tissues [PhD thesis]. Duke University; 2013.
2013	Mhanna R. Engineering Chondrogenic Micro-Environments for Tissue Engineering Applications [PhD thesis]. Swiss Federal Institute of Technology Zürich; 2013.
2013	Nebuloni L. Monitoring Angiogenesis in Tissue Engineering Through Time-Lapsed Vascular Imaging [PhD thesis]. Swiss Federal Institute of Technology Zürich; 2013.
2014	Wüst S. 3D Bioprinting of Multicellular Skeletal Tissues [PhD thesis]. Swiss Federal Institute of Technology Zürich; 2014.
2015	Millan CA. Formation of Engineered Microtissues by Schiff Base Crosslinking [PhD thesis]. Swiss Federal Institute of Technology Zürich; 2015.
2016	Müller M. Material Development for the 3D Printing of Osteochondral Grafts [PhD thesis]. Swiss Federal Institute of Technology Zürich; 2016.
2018	Cavalli E. Cell‐based Injectable Therapies for Cartilage Repair [PhD thesis]. Swiss Federal Institute of Technology Zürich; 2018.
2018	Formica FA. From Electrospinning to Protein Engineering: Novel Approaches for Cartilage Repair [PhD thesis]. Swiss Federal Institute of Technology Zürich; 2018.
2020	Levinson CSJ. From Bedside to Bench and Back: Translatable Approaches for Cartilage Repair [PhD thesis]. Swiss Federal Institute of Technology Zürich; 2020.
2004	Gallant ND. Analysis of Integrin-Mediated Cell Adhesion Strengthening Using Surfaces Engineered to Control Cell Shape and Focal Adhesion Assembly [PhD thesis]. Atlanta, GA: Georgia Institute of Technology; November 2004.
2004	Benjamin G. Keselowsky. Engineering Surfaces to Direct Integrin Binding and Signaling to Promote Osteoblast Differentiation [PhD thesis]. Atlanta, GA: Georgia Institute of Technology; May 2004.
2005	Capadona JR. Surface-Directed Assembly of Fibrillar Extracellular Matrices [PhD thesis]. Atlanta, GA: Georgia Institute of Technology; May 2005.
2006	Michael KE. FAK Modulates Cell Adhesion Strengthening Via Two Distinct Mechanisms: Integrin Binding and Vinculin Localization [PhD thesis]. Atlanta, GA: Georgia Institute of Technology; December 2006.
2006	Vanderploeg EJ. Mechanotransduction in Engineered Cartilaginous Tissues: In Vitro Oscillatory Tensile Loading [PhD thesis]. Atlanta, GA: Georgia Institute of Technology; August 2006.
2008	Bridges AW. Host Responses to Microgel-Based Biomaterial Interfaces [PhD thesis]. Atlanta, GA: Georgia Institute of Technology; December 2008.
2009	Deutsch ER. The Use of Stem Cell Synthesized Extracellular Matrix for Bone Repair [Master's thesis]. Atlanta, GA: Georgia Institute of Technology; December 2009.
2009	Wojtowicz AM. Genetically-Engineered Bone Marrow Stromal Cells and Collagen Mimetic Scaffold Modification for Healing Critically-Sized Bone Defects [PhD thesis]. Atlanta, GA: Georgia Institute of Technology; August 2009.
2009	Kolambkar YM. Electrospun Nanofiber Meshes for the Functional Repair of Bone Defects [PhD thesis]. Atlanta, GA: Georgia Institute of Technology; December 2009.
2010	Dupont KM. Human Stem Cell Delivery and Programming for Functional Regeneration of Large Segmental Bone Defects [PhD thesis]. Atlanta, GA: Georgia Institute of Technology; May 2010.
2021	Anderson SE. Aberrant Cellular Response and Muscle Regeneration Following Volumetric Muscle Loss [PhD thesis]. Atlanta, GA: Georgia Institute of Technology; August 2021.
206	Chen Y. Developing Bioactive Composite Scaffolds for Bone Tissue Engineering [PhD thesis]. Hong Kong Polytechnic University; October 206.
2008	Singh M. Osteochondral Tissue Engineering for the TMJ Condyle Using a Novel Gradient Scaffold [PhD thesis]. Lawrence, KS: University of Kansas; 2008.
2010	Rami E. Automated Design of Trabecular Structures [PhD thesis]. Loughborough, UK: Loughborough University; February 2010.
2013	Khayat G. Low Frequency Stimulation of Stem Cells in Dynamic Culture Modulates Differentiation Pathways [PhD thesis]. McGill University; July 2013.
2011	Yuan T-Y. Innovative Methods to Determine Material Properties of Cartilaginous Tissues and Application for Tissue Engineering [PhD thesis]. University of Miami; August 2011.
1997	Bhatia SN. Controlling Cell-Cell Interactions in Hepatic Tissue Engineering Using Microfabrication [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; June 1997.
2002	Lee CR. Behavior of Passaged Chondrocytes in Collagen-Glycosaminoglycan Scaffolds: Effects of Cross-Linking, Mechanical Loading, and Genetic Modification of the Scaffold [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; February 2002.
2022	Panebianco CJ. Engineering Composite Hydrogels and Discovering Novel Cell Populations for Next-Generation Intervertebral Disc Repair [PhD thesis]. Icahn School of Medicine at Mount Sinai; March 2022.
2013	Snyder KL. Development of Vapor Deposited Silica Sol-Gel Particles for a Bioactive Materials System to Direct Osteoblast Behavior [PhD thesis]. Houghton, MI: Michigan Technological University; 2013.
2012	Samberg M. Biological Interactions of Silver Nanoparticles [PhD thesis]. North Carolina State University; 2012.
2003	Harbers GM. Biomimetic Surface Engineering to Study Osteoblast Adhesion and Matrix Mineralization [PhD thesis]. Evanston, IL: Northwestern University; December 2003.
2013	Weiss HE. Engineering a Replacement Bone Tissue With Adult Adipose-Derived Stem Cells [PhD thesis]. University of Notre Dame; April 2013.
2021	Olivier C. Evaluation of the in Vitro Biocompatibility of Cortical Bone Matrix [Master's thesis]. Potchefstroom, South Africa: North-West University; November 2021.
2018	De Mori A. Silver Nanowires and Their Potential Use as 3D Scaffolds for Biomedical Applications [PhD thesis]. Portsmouth, England: University of Portsmouth; October 2018.
2018	Yang F. The Synergistic Effect of Bone Graft Substitute Architecture and Mechanical Environment on HMSCs Responses in Vitro [PhD thesis]. Queen Mary University of London; December 2018.
2007	Ilagan BG. The Development of an Elastomeric Scaffold for Small Diameter Blood Vessel Tissue Engineering [Master's thesis]. Queen's University; November 2007.
2011	Surrao DC. Biomimetic Scaffolds for Ligament Tissue Engineering [PhD thesis]. Queen's University; December 2011.
2012	Khan AA. Effects of Additional Sodium Bicarbonate on Extra/intra Cellular Factors in a Continuous Flow Bioreactor for the Production of Tissue Engineered Articular Cartilage [PhD thesis]. Queen's University; October 2012.
2010	Schrobback K. In Vitro Cultivation of Adult Human Chondrocytes: Importance of Culture System, Oxygen and Zonal Differences [PhD thesis]. Queensland University of Technology; 2010.
2011	Jeon JE. Development of Zonal Cartilage Constructs: Effects of Chondrocyte Subpopulation, Compressive Stimulation, and Culture Models [PhD thesis]. Queensland University of Technology; 2011.
2015	Bartnikowski M. Design and Characterisation of Scaffolds for Osteochondral Regeneration [PhD thesis]. Queensland University of Technology; December 2015.
2016	Levett PA. Photocrosslinkable Hydrogels for Cartilage Tissue Engineering [PhD thesis]. Queensland University of Technology; 2016.
2017	Meinert AC. Hydrogels and Bioreactors for Cartilage Research and Functional Tissue Engineering [PhD thesis]. Queensland University of Technology; 2017.
2021	Pahoff S. Fibre-Reinforced Hydrogels for Functional Cartilage Tissue Engineering [PhD thesis]. Queensland University of Technology; 2021.
2013	Viswanathan P. In Situ Surface Functionalisation of Scaffolds Using Block Copolymer Self-Assembly [PhD thesis]. University of Sheffield; 2013.
2008	Arnsdorf EJ. Guiding Osteogenic Lineage Commitment: The Role of Mesenchymal Stem Cell Biology and the Mechanical Microenvironment [PhD thesis]. Stanford University; September 2008.
2010	Lee WJ. Liver Tissue Engineering Based on Poly (ethylene Glycol) Hydrogels [PhD thesis]. Stanford University; March 2010.
2008	Unnikrishnan GU. Computational Modeling of Biological Cells and Soft Tissues [PhD thesis]. Texas A&M University; May 2008.
2007	McMahon LA. The Effect of Cyclic Tensile Loading and Growth Factors on the Chondrogenic Differentiation of Bone-Marrow Derived Mesenchymal Stem Cells in a Collagen-Glycosaminoglycan Scaffold [PhD thesis]. Trinity College Dublin; September 2007.
2015	Li H. Neural Stem/progenitor Cell 3-D Differentiation for Repair of Central Nervous System Injuries [PhD thesis]. University of Akron; May 2015.
2017	Mohrman AE. Regenerative Medicine Approaches to Spinal Cord Injury [PhD thesis]. University of Akron; March 2017.
1999	Awad HA. Mesenchymal Stem Cell Seeded Collagen Scaffolds for Tendon Repair [PhD thesis]. University of Cincinnati; 1999.
2011	Hurley JR. Tissue Engineering Strategies for Cardiac Regeneration [PhD thesis]. University of Cincinnati; October 2011.
2012	Cho H. Nanofiber-Based Therapy for Diabetic Wound Healing: A Mechanistic Study [PhD thesis]. University of Cincinnati; September 2012.
2004	Kazakia GJ. Development, Analysis, and Imaging of a Tissue Engineered Trabecular Bone Substitute [PhD thesis]. Berkeley, CA: Berkeley, University of California; 2004.
2013	Soicher MA. Fabrication and Characterization of Remineralized Bone Matrices (RBM) for Use as Bone Tissue Engineering Substrates [PhD thesis]. Davis, University of California; 2013.
2020	Salinas EY. Using Mechanical Stimulation to Improve Tissue-Engineered Articular Cartilage for Implantation in the Knee Joint [PhD thesis]. Irvine, CA: Irvine, University of California; 2020.
2005	Albrecht DR. Microscale Organization of Cells Within 3-D Hydrogels by Dielectrophoresis: Applications to Cartilage Biology [PhD thesis]. San Diego (UCSD), University of California; 2005.
2008	Rosines E. Developmental Approaches to in Vitro Engineering of Kidney-Like Tissues [PhD thesis]. San Diego (UCSD), University of California; 2008.
2009	Hsieh-Bonassera ND. Cartilage Tissue Engineering With Human Chondrocytes from Osteoarthritic Knees and a Semi-Permeable Membrane [PhD thesis]. San Diego (UCSD), University of California; 2009.
2010	Hwang J. Integration of Cartilage and Bone Through a Calcified Cartilage Interface to Form a Functional Osteochondral Graft [PhD thesis]. San Diego (UCSD), University of California; 2010.
2004	Lin C-Y. A New Spine Interbody Fusion System: Integrating Topology Optimized Biodegradable Interbody Fusion Cages With Cell-Based and Ex Vivo Gene Therapy [PhD thesis]. University of Michigan; 2004.
2004	Schek RM. The Use of Designed, Solid Free Form Scaffolds for Gene Therapy Directed Bone Tissue Engineering [PhD thesis]. University of Michigan; 2004.
2005	Lin C-Y. Solid-Fluid Mixture Microstructure Design of Composite Materials With Application to Tissue Engineering Scaffold Design [PhD thesis]. University of Michigan; 2005.
2006	Jongpaiboonkit L. Calcium Phosphate Scaffolds for Bone Tissue Engineering and Self-Association PEG-PLLA Diblock Copolymer for Controlled Drug Delivery System [PhD thesis]. University of Michigan; 2006.
2007	Liao EE. Enhancement of Chondrogenesis by Directing Cellular Condensation Through Chondroinductive Microenvironments, And, Designed Solid Freeform Fabricated Scaffolds [PhD thesis]. University of Michigan; 2007.
2007	Rossello RA. Cell-to-Cell Communication as a Strategy to Regenerate Three-Dimensional Tissue [PhD thesis]. University of Michigan; 2007.
2007	Wong DY. Anatomically Inspired Scaffold Design Enhances Tissue Regeneration in Brain and Spinal Cord [PhD thesis]. University of Michigan; 2007.
2008	Segvich SJ. Design of Peptides With Targeted Apatite and Human Bone Marrow Stromal Cell Adhesion for Bone Tissue Engineering [PhD thesis]. University of Michigan; 2008.
2010	Kang HS. Hierarchical Design and Simulation of Tissue Engineering Scaffold Mechanical, Mass Transport, and Degradation Properties [PhD thesis]. University of Michigan; 2010.
2022	Davidson CD. Biomaterial Control of Cell Forces to Enable Intercellular Communication During Vasculogenic Assembly [PhD thesis]. University of Michigan; 2022.
1996	García AJ. Quantitative Analysis of Fibronectin-Mediated Adhesion of Osteoblast-Like Cells to Bioactive Glass and Hydroxyapatite [PhD thesis]. Philadelphia, PA: University of Pennsylvania; 1996.
1998	Gan JCC. Tissue Engineering for Intervertebral Disc Repair [PhD thesis]. Philadelphia, PA: University of Pennsylvania; 1998.
2005	Lee MH. Optimization of Surface-Immobilized Peptide/protein Presentation for Control of the Biological Activity of Substrates for Tissue Engineering Applications [PhD thesis]. Philadelphia, PA: University of Pennsylvania; 2005.
2011	Silverman LI. Enhancing Meniscus Repair Through Biomaterial Design [PhD thesis]. Philadelphia, PA: University of Pennsylvania; 2011.
2017	Kim M. Multi-Cellular and Multi-Scale Approaches for Cartilage Repair [PhD thesis]. Philadelphia, PA: University of Pennsylvania; 2017.
2022	Blázquez Carmona P. Mechanobiology of Bone Regeneration: Distraction Osteogenesis and Tissue Engineering [PhD thesis]. Universidad de Sevilla; 2022.
2011	Kempen DHR. Bone Regeneration Based on Growth Factor Releasing Polymer Composites [PhD thesis]. Utrecht University; 2011.
2014	Pourmohammadali H. Mechanical and Hydromechanical Stimulation of Chondrocytes for Articular Cartilage Tissue Engineering [PhD thesis]. University of Waterloo; 2014.
2014	Vlasea M. Additive Manufacturing Methodology and System for Fabrication of Porous Structures With Functionally Graded Properties [PhD thesis]. University of Waterloo; 2014.
2011	Vivanco Morales JF. Investigation of Fabrication and Environmental Effects on Bioceramic Bone Scaffolds [PhD thesis]. University of Wisconsin – Madison; 2011.

Year	Entry
1989	Grande DA, Pitman MI, Peterson L, Menche D, Klein M. The repair of experimentally produced defects in rabbit articular cartilage by autologous chondrocyte transplantation. J Orthop Res. March 1989;7(2):208-218.
1992	Buschmann MD, Gluzband YA, Grodzinsky AJ, Kimura JH, Hunziker EB. Chondrocytes in agarose culture synthesize a mechanically functional extracellular matrix. J Orthop Res. November 1992;10(6):745-758.