Prediction of vertebral strength by dual photon absorptiometry and quantitative computed tomography

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Eriksson, Staffan A. V.¹; Isberg, Bengt O.²; Lindgren, J. Urban¹

Prediction of vertebral strength by dual photon absorptiometry and quantitative computed tomography

Calcif Tiss Int. April 1989;44(4):243-250

©1989 Springer-Verlag New York Inc.

Affiliations

¹Department of Orthopaedic Surgery, Karolinska Institute, Huddinge University Hospital, Huddinge, Sweden

²Department of Diagnostic Radiology, Karolinska Institute, Huddinge University Hospital, Huddinge, Sweden
Abstract and keywords

We measured the lumbar bone mineral of 19 cadavers (10 women, 9 men) by dual photon absorptiometry (DPA) and quantitative computed tomography (QCT). In addition, we determined the ultimate load and stress of each vertebra, and finally ash content and volumetric ash density of the vertebral body. We found that single energy QCT was inferior to DPA and dual energy QCT in the prediction of the ultimate load or stress of vertebrae (P<0.001). The ultimate stress of predicted by using the dual energy QCT results (r=0.71; SEE=36.3 N/cm²) whereas the ultimate vertebral load was best predicted by using the DPA (BMC) results (r=0.80; SEE=740 N). If the QCT finding was multiplied with the surface area of the vertebral body it could be used to predict the ultimate load with good accuracy (r=0.74; SEE=841 N). All the above correlations were higher in women than in men. The frequency of vertebral compression fractures in the material was wel correlated with the bone mineral findings. A nonlinear (third degree) relationship between mineral content and mechanical characteristics is proposed but within the area of measurement used in clinical practice a linear (first degree) equation is preferred.

Keywords: Lumbar bone mineral content; Quantitative computed tomography; Dual photon absorptiometry; Load and stress
Links

DOI: 10.1007/BF02553758

PubMed: 2501006

WoS: A1989U078500002
History

Received: 1987-07-31

Revised: 1988-05-27

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Cited By (25)

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2011	Wagnac É. Expérimentation et modélisation détaillée de la colonne vertébrale pour étudier le rôle de facteurs anatomiques et biomécaniques sur les traumatismes rachidiens [PhD thesis]. École polytechnique de Montréal; November 2011.
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2011	Howarth SJ. Mechanical Response of the Porcine Cervical Spine to Acute and Repetitive Anterior-Posterior Shear [PhD thesis]. University of Waterloo; 2011.