Creep does not contribute to fatigue in bovine trabecular bone

Moore, T. L. A.<sup>1</sup>; O’Brien, F. J.<sup>2</sup>; Gibson, L. J.<sup>3</sup>

Affiliations

¹Exponent Failure Analysis Associates, Philadelphia, PA 19106

²Department of Anatomy, Royal College of Surgeons in Ireland, Dublin 2, Ireland

³Department of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139

Abstract and keywords

In both cortical and trabecular bone loaded in fatigue, the stress-strain loops translate along the strain axis. Previous studies have suggested that this translation is the result of creep associated with the mean stress applied in the fatigue test. In this study, we measured the residual strain (corresponding to the translation of the stress-strain loops) in fatigue tests on bovine trabecular bone and compared it to an upper bound estimate of the creep strain in each test. Our results indicate that the contribution of creep to the translation of the stress-strain loops is negligible in bovine trabecular bone. These results, combined with models for fatigue in lower density bone, suggest that that creep does not contribute to the fatigue of normal human bone. Creep may make a significant contribution to fatigue in low-density osteoporotic bone in which trabeculae have resorbed, reducing the connectivity of the trabecular structure.

Keywords:

Links

DOI: 10.1115/1.1762892

PubMed: 15341168

WoS: 000222620100001

History

Received: 2003-06-16

Revised: 2003-12-04

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2006	Rapillard L, Charlebois M, Zysset PK. Compressive fatigue behavior of human vertebral trabecular bone. J Biomech. 2006;39(11):2133-2139.
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2011	Green JO, Wang J, Diab T, Vidakovic B, Guldberg RE. Age-related differences in the morphology of microdamage propagation in trabecular bone. J Biomech. October 13, 2011;44(15):2659-2666.
2021	Frank M, Fischer J-T, Thurner PJ. Microdamage formation in individual bovine trabeculae during fatigue testing. J Biomech. January 22, 2021;115:110131.
2013	Lambers FM, Bouman AR, Rimnac CM, Hernandez CJ. Microdamage caused by fatigue loading in human cancellous bone: relationship to reductions in bone biomechanical performance. PLoS One. December 2013;8(12):e83662.
2018	Xie S. Characterisation of Time-Dependent Mechanical Behaviour of Trabecular Bone and Its Constituents [PhD thesis]. Edinburgh, Scotland: University of Edinburgh; 2018.
2006	Nagaraja S. Microstructural Stresses and Strains Associated With Trabecular Bone Microdamage [PhD thesis]. Atlanta, GA: Georgia Institute of Technology; December 2006.
2011	O'Neal JM. The Effects of Aging and Remodeling on Bone Quality and Microdamage [PhD thesis]. Atlanta, GA: Georgia Institute of Technology; August 2011.
2012	Tozzi G. In Vitro Studies of Bone-Cement Interface and Related Work on Cemented Acetabular Replacement [PhD thesis]. Portsmouth, England: University of Portsmouth; May 29, 2012.
2005	Buie HR. Use of Finite Element Method Modelling and Rapid Prototyping to Study the Effect of Trabecular Bone Architecture on Apparent Mechanical Properties [Master's thesis]. Queen's University; November 2005.
2019	Heney AP. Effect of Fatigue-Induced Microdamage on the Compressive Properties of Bovine Trabecular Bone [Master's thesis]. Queen's University; September 2019.
2021	Frank M. Mechanical Characterization of Individual Trabeculae [PhD thesis]. Vienna University of Technology; February 2021.
2008	Parkinson RJ. Refining the Relationship Between the Mechanical Demands on the Spine and Injury Mechanisms Through Improved Estimates of Load Exposure and Tissue Tolerance [PhD thesis]. University of Waterloo; 2008.