Automated three-dimensional finite element modelling of bone:​ a new method

Keyak, J. H.; Meagher, J. M.; Skinner, H. B.; Mote, Jr, C. D.

Year	Entry
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2000	Halldin PH, Brolin K, Kleiven S, von Holst H, Jakobsson L, Palmertz C. Investigation of conditions that affect neck compression-flexion injuries using numerical techniques. Stapp Car Crash J. 2000;44:127-138. SAE 2000-01-SC10.
2000	Cody DD, Hou FJ, Divine GW, Fyhrie DP. Short term in vivo precision of proximal femoral finite element modeling. Ann Biomed Eng. April 2000;28(4):408-414.
2010	Keaveny TM. Biomechanical computed tomography: noninvasive bone strength analysis using clinical computed tomography scans. Annals NY Acad Sci. 2010;1192(1):57-65.
2003	Crawford RP, Cann CE, Keaveny TM. Finite element models predict in vitro vertebral body compressive strength better than quantitative computed tomography. Bone. 2003;33(4):744-750.
2006	Hernandez CJ, Keaveny TM. A biomechanical perspective on bone quality. Bone. December 2006;39(6):1173-1181.
2020	Varga P, Willie BM, Stephan C, Kozloff KM, Zysset PK. Finite element analysis of bone strength in osteogenesis imperfecta. Bone. April 2020;133:115250.
2020	Keyak JH, Kaneko TS, Khosla S, Amin S, Atkinson EJ, Lang TF, Sibonga JD. Hip load capacity and yield load in men and women of all ages. Bone. August 2020;137:115321.
2008	Helgason B, Perilli E, Schileo E, Taddei F, Brynjólfsson S, Viceconti M. Mathematical relationships between bone density and mechanical properties: a literature review. Clin Biomech (Bristol, Avon). 2008;23(2):135-146.
2009	Dai Y, Niebur GL. A semi-automated method for hexahedral mesh construction of human vertebrae from CT scans. Comput Methods Biomech Biomed Eng. 2009;12(5):599-606.
2009	Grosland NM, Shivanna KH, Magnotta VA, Kallemeyn NA, DeVries NA, Tadepalli SC, Lisle C. IA-FEMesh: an open-source, interactive, multiblock approach to anatomic finite element model development. Comput Methods Prog Biomed. April 2009;94(1):96-107.
1997	Camacho DLA, Hopper RH, Lin GM, Myers BS. An improved method for finite element mesh generation of geometrically complex structures with application to the skullbase. J Biomech. 1997;30(10):1067-1070.
1998	Keyak JH, Rossi SA, Jones KA, Skinner HB. Prediction of femoral fracture load using automated finite element modeling. J Biomech. February 1998;31(2):125-133.
1999	Ulrich D, van Rietbergen B, Laib A, Rüegsegger P. Load transfer analysis of the distal radius from in-vivo high-resolution CT-imaging. J Biomech. August 1999;32(8):821-828.
1999	Cody DD, Gross GJ, Hou FJ, Spencer HJ, Goldstein SA, Fyhrie DP. Femoral strength is better predicted by finite element models than QCT and DXA. J Biomech. October 1999;32(10):1013-1020.
1999	Jacobs CR, Davis BR, Rieger CJ, Francis JJ, Saad M, Fyhrie DP. The impact of boundary conditions and mesh size on the accuracy of cancellous bone tissue modulus determination using large-scale finite-element modeling. J Biomech. November 1999;32(11):1159-1164.
2000	Keyak J, Rossi S. Prediction of femoral fracture load using finite element models: an examination of stress- and strain-based failure theories. J Biomech. 2000;33(2):209-214.
2000	Charras GT, Guldberg RE. Improving the local solution accuracy of large-scale digital image-based finite element analyses. J Biomech. February 2000;33(2):255-259.
2000	Weinans H, Sumner DR, Igloria R, Natarajan RN. Sensitivity of periprosthetic stress-shielding to load and the bone density–modulus relationship in subject-specific finite element models. J Biomech. July 2000;33(7):809-817.
2000	Couteau B, Payan Y, Lavallée S. The mesh-matching algorithm: an automatic 3d mesh generator for finite element structures. J Biomech. August 2000;33(8):1005-1009.
2006	Taddei F, Cristofolini L, Martelli S, Gill HS, Viceconti M. Subject-specific finite element models of long bones: an in vitro evaluation of the overall accuracy. J Biomech. 2006;39(13):2457-2467.
2006	Verhulp E, van Rietbergen B, Huiskes R. Comparison of micro-level and continuum-level voxel models of the proximal femur. J Biomech. 2006;39(16):2951-2957.
2007	Yosibash Z, Trabelsi N, Milgrom C. Reliable simulations of the human proximal femur by high-order finite element analysis validated by experimental observations. J Biomech. 2007;40(16):3688-3699.
2008	Burgers TA, Mason J, Niebur G, Ploeg HL. Compressive properties of trabecular bone in the distal femur. J Biomech. 2008;41(5):1077-1085.
2009	Trabelsi N, Yosibash Z, Milgrom C. Validation of subject-specific automated p-FE analysis of the proximal femur. J Biomech. February 9, 2009;42(3):234-241.
2011	Trabelsi N, Yosibash Z, Wutte C, Augat P, Eberle S. Patient-specific finite element analysis of the human femur: a double-blinded biomechanical validation. J Biomech. June 3, 2011;44(9):1666-1672.
2020	Ascenzi M-G, Zonca A, Keyak JH. Effect of cortical bone micro-structure in fragility fracture patients on lamellar stress. J Biomech. February 13, 2020;100:109596.
1996	Merz B, Niederer P, Müller R, Rüegsegger P. Automated finite element analysis of excised human femora based on precision-QCT. J Biomech Eng. August 1996;118(3):387-390.
1998	Guldberg RE, Hollister SJ, Charras GT. The accuracy of digital image-based finite element models. J Biomech Eng. 1998;120(2):289-295.
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2003	Crawford RP, Rosenberg WS, Keaveny TM. Quantitative computed tomography-based finite element models of the human lumbar vertebral body: effect of element size on stiffness, damage, and fracture strength predictions. J Biomech Eng. August 2003;125(4):434-438.
2007	Yosibash Z, Padan R, Joskowicz L, Milgrom C. A CT-based high-order finite element analysis of the human proximal femur compared to in-vitro experiments. J Biomech Eng. June 2007;129(3):297-309.
2011	Trabelsi N, Yosibash Z. Patient-specific finite-element analyses of the proximal femur with orthotropic material properties validated by experiments. J Biomech Eng. June 2011;133(6):061001.
2011	Unnikrishnan GU, Morgan EF. A new material mapping procedure for quantitative computed tomography-based, continuum finite element analyses of the vertebra. J Biomech Eng. July 2011;133(7):071001.
2014	Chen Y, Pani M, Taddei F, Mazzà C, Li X, Viceconti M. Large-scale finite element analysis of human cancellous bone tissue micro computer tomography data: a convergence study. J Biomech Eng. October 2014;136(10):101013.
1992	Keyak JH, Skinner HB. Three-dimensional finite element modelling of bone: effects of element size. J Biomed Eng. 1992;14(6):483-489.
1993	Keyak JH, Fourkas MG, Meagher JM, Skinner HB. Validation of an automated method of three-dimensional finite element modelling of bone. J Biomed Eng. November 1993;15(6):505-509.
1999	Ota T, Yamamoto I, Morita R. Fracture simulation of the femoral bone using the finite-element method: how a fracture initiates and proceeds. J Bone Min Metab. May 1999;17(2):108-112.
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1995	Bandak FA, Vander Vorst MJ, Stuhmiller LM, Mlakar PF, Chilton WE, Stuhmiller JH. An imaging-based computational and experimental study of skull fracture: finite element model development. J Neurotrauma. August 1995;12(4):679-688.
1994	Skinner HB, Kim AS, Keyak JH, Mote CD Jr. Femoral prosthesis implantation induces changes in bone stress that depend on the extent of porous coating. J Orthop Res. July 1994;12(4):553-563.
1994	Les CM, Keyak JH, Stover SM, Taylor KT, Kaneps AJ. Estimation of material properties in the equine metacarpus with use of quantitative computed tomography. J Orthop Res. November 1994;12(6):822-833.
1998	Silva MJ, Keaveny TM, Hayes WC. Computed tomography-based finite element analysis predicts failure loads and fracture patterns for vertebral sections. J Orthop Res. May 1998;16(3):300-308.
2001	Keyak JH, Skinner HB, Fleming JA. Effect of force direction on femoral fracture load for two types of loading conditions. J Orthop Res. July 2001;19(4):539-544.
1994	Bozic KJ, Keyak JH, Skinner HB, Bueff UH, Bradford DS. Three-dimensional finite element modeling of a cervical vertebra an investigation of burst fracture mechanism. J Spinal Disord. April 1994;7(2):102-110.
1995	Müller R, Rüegsegger P. Three-dimensional finite element modelling of non-invasively assessed trabecular bone structures. Med Eng Phys. March 1995;17(2):126-133.
1995	Rho JY, Hobatho MC, Ashman RB. Relations of mechanical properties to density and CT numbers in human bone. Med Eng Phys. July 1995;17(5):347-355.
1998	Viceconti M, Bellingeri L, Cristofolini L, Toni A. A comparative study on different methods of automatic mesh generation of human femurs. Med Eng Phys. January 1998;20(1):1-10.
1998	Lengsfeld M, Schmitt J, Alter P, Kaminsky J, Leppek R. Comparison of geometry-based and CT voxel-based finite element modelling and experimental validation. Med Eng Phys. October 1998;20(7):515-522.
1998	Zannoni C, Mantovani R, Viceconti M. Material properties assignment to finite element models of bone structures: a new method. Med Eng Phys. December 1998;20(10):735-740.
2001	Keyak JH. Improved prediction of proximal femoral fracture load using nonlinear finite element models. Med Eng Phys. April 2001;23(3):165-173.
2001	Keyak JH, Rossi SA, Jones K, Les CM, Skinner HB. Prediction of fracture location in the proximal femur using finite element models. Med Eng Phys. November 2001;23(9):657-664.
2003	Keyak JH, Falkinstein Y. Comparison of in situ and in vitro CT scan-based finite element model predictions of proximal femoral fracture load. Med Eng Phys. November 2003;25(9):781-787.
2005	Kaminsky J, Rodt T, Gharabaghi A, Forster J, Brand G, Samii M. A universal algorithm for an improved finite element mesh generation: mesh quality assessment in comparison to former automated mesh-generators and an analytic model. Med Eng Phys. 2005;27(5):383-394.
2007	Taddei F, Schileo E, Helgason B, Cristofolini L, Viceconti M. The material mapping strategy influences the accuracy of ct-based finite element models of bones: an evaluation against experimental measurements. Med Eng Phys. 2007;29(9):973-979.
2008	Helgason B, Taddei F, Pálsson H, Schileo E, Cristofolini L, Viceconti M, Brynjolfsson S. A modified method for assigning material properties to FE models of bones. Med Eng Phys. May 2008;30(4):444-453.
2019	Yue Y, Yang H, Li Y, Zhong H, Tang Q, Wang J, Wang R, He H, Chen W, Chen D. Combining ultrasonic and computed tomography scanning to characterize mechanical properties of cancellous bone in necrotic human femoral heads. Med Eng Phys. April 2019;66:12-17.
2010	Cristofolini L, Schileo E, Juszczyk M, Taddei F, Martelli S, Viceconti M. Mechanical testing of bones: the positive synergy of finite–element models and in vitro experiments. Philos Trans R Soc A-Math Phys Eng Sci. June 13, 2010;368(1920):2725-2763.
1991	Faulkner KG, Cann CE, Hasegawa BH. Effect of bone distribution on vertebral strength: assessment with patient-specific nonlinear finite element analysis. Radiology. June 1991;179(3):669-674.
1999	Taylor WR. A Computer Based Technique for Predicting Changes in Bone Properties With Applications in Pre-Clinical Testing of Hip Implants [PhD thesis]. University of Bath; 1999.
2016	Haider IT. An Investigation on the Influence of Stumbling Loads on Femoral Fracture Risk, Using a Novel Gradient Enhanced Quasibrittle Finite Element Model [PhD thesis]. Carleton University; 2016.
2024	Szabo E. Insights Into the Mechanical Behavior of Maturing Cortical Bone: A Porcine Model [PhD thesis]. Cleveland, OH: Case Western Reserve University; May 2024.
2009	Baldwin M. Explicit Finite Element Modeling of Knee Mechanics During Simulated Dynamic Activities [PhD thesis]. University of Denver; June 2009.
1998	Camacho DLA. Dynamic Response of the Head and Cervical Spine to Near-Vertex Head Impact: An Experimental and Computational Study [PhD thesis]. Duke University; 1998.
2019	Fleps I. Assessing the Risk of Hip Fracture: Subject-Specific Dynamic Models for the Simulation of Sideways Fall Impact [PhD thesis]. Swiss Federal Institute of Technology Zürich; 2019.
1999	Bull AMJ. Measurement and Computer Simulation of Knee Kinematics [PhD thesis]. Imperial College London; 1999.
2013	Li S. Cutting of Cortical Bone Tissue: Analysis of Deformation and Fracture Process [PhD thesis]. Loughborough University; June 2013.
2022	Grumbles D. Response Surface Optimization to Determine Validity Range for Density Modulus Relationship on Intact Ovine Tibiae [Master's thesis]. Lehigh University; August 2022.
2006	Yang S. Animal Experiment (rabbit) to Demonstrate Changes in Trabecular Bone Mechanical Properties Over Time Using Finite Element Analysis [PhD thesis]. Louisville, KY: University of Louisville; December 2006.
2013	Vijayakumar V. Quantifying the Regional Variations in the Mechanical Properties of Cancellous Bone of the Tibia Using Indentation Testing and CT Imaging [Master's thesis]. Hamilton, ON: McMaster University; September 2013.
1999	Schaffner G. Assessment of Hip Fracture Risk in Astronauts Exposed to Long-Term Weightlessness [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; August 1999.
2009	Pfeiler TW. Computational and Experimental Analyses of Bone and Adult Stem Cell Mechanobiology [PhD thesis]. North Carolina State University; 2009.
2009	Dai Y. Subject-Specific Computational Modeling of Spinal Constructs [PhD thesis]. University of Notre Dame; April 2009.
2015	Gargac J. Evaluation of Bone Healing, Damage, and Adaptation Using Computational Modeling and Image Processing Techniques [PhD thesis]. University of Notre Dame; July 2015.
2016	Metzger TA. Experimental and Computational Investigation of Bone Marrow Mechanobiology [PhD thesis]. University of Notre Dame; April 2016.
2018	Zimmermann Y. Développement d'une modélisation par éléments finis pour caractérisation non destructive de la biomécanique osseuse à partir d'images MICRO-CT [Master's thesis]. École polytechnique de Montréal; December 2018.
2013	Morton JJ. An Investigation of Rat Vertebra Failure Behaviour Under Uniaxial Compression Through Time-Lapsed Micro-CT Imaging [Master's thesis]. Queen's University; 2013.
2024	Cameron E. Knee Joint Loading and Fracture Risk Analyses of Patients With Benign Bone Tumours: A Finite Element Analysis [Master's thesis]. Queen's University; August 15, 2024.
2023	Branni MG. Constitutive Models of Bone: The Human Femur [PhD thesis]. Queensland University of Technology; 2023.
2012	Emerson NJ. Development of Patient-Specific CT-FE Modelling of Bone Through Validation Using Porcine Femora [PhD thesis]. University of Sheffield; September 2012.
2016	Chen Y. Verification and Validation of MicroCT-Based Finite Element Models of Bone Tissue Biomechanics [PhD thesis]. Sheffield, UK: University of Sheffield; July 2016.
1998	Giddings VL. Computer Simulations of Calcaneal Loading and Bone Adaptation [PhD thesis]. Stanford University; June 1998.
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2010	Manske SL. Muscle Disuse and Vibration Effects on Bone Morphology [PhD thesis]. Calgary, AB: University of Calgary; December 2010.
2013	Enns-Bray WS. Mapping Anisotropy of the Proximal Femur for Improved Image-Based Finite Element Analysis [Master's thesis]. Calgary, AB: University of Calgary; August 2013.
2016	Firminger CR. Effects of Minimalist Footwear and Stride Length Reduction on Metatarsal Strains and the Probability of Stress Fracture in Running [Master's thesis]. Calgary, AB: University of Calgary; July 2016.
2023	Bruce OL. Tibial-Fibular Morphology: Variation, Sexual Dimorphism, and Mechanical Implications [PhD thesis]. Calgary, AB: University of Calgary; May 2023.
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1998	Kopperdahl DL. Structural Consequences of Damage on the Mechanical Behavior of the Human Vertebral Body [PhD thesis]. Berkeley, CA: Berkeley, University of California; 1998.
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2006	Jongpaiboonkit L. Calcium Phosphate Scaffolds for Bone Tissue Engineering and Self-Association PEG-PLLA Diblock Copolymer for Controlled Drug Delivery System [PhD thesis]. University of Michigan; 2006.
2018	Hosseini Kalajahi SM. Addressing Partial Volume Artifacts With Quantitative Computed Tomography-Based Finite Element Modeling of the Human Proximal Tibia [Master's thesis]. University of Saskatchewan; April 2018.
1999	Pellettiere JA. A Dynamic Material Model for Bone [PhD thesis]. Charlottesville, VA: University of Virginia; January 1999.
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