Compressive properties of trabecular bone in the distal femur

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Burgers, Travis A.¹; Mason, Jim²; Niebur, Glen³; Ploeg, Heidi L.¹

Compressive properties of trabecular bone in the distal femur

J Biomech. 2008;41(5):1077-1085

Affiliations

¹Mechanical Engineering Department, University of Wisconsin, Madison, WI, USA

²Research Laboratory, Zimmer Inc., Warsaw, IN, USA

³Aerospace and Mechanical Engineering Department, University of Notre Dame, South Bend, IN, USA
Abstract and keywords

Early loosening and implant migration are two problems that lead to failures in cementless (press-fit) femoral knee components of total knee replacements. To begin to address these early failures, this study determined the anterior–posterior mechanical properties from four locations in the human distal femur. Thirty-three cylindrical specimens were removed perpendicular to the press-fit surface after the surgical cuts on 10 human cadaveric femurs (age 71.5±14.2 years) had been made. Compression testing was performed that utilized methods to reduce the effects of end-artifacts. The bone mineral apparent density (BMAD), apparent modulus of elasticity, yield and ultimate stress, and yield and ultimate strain were measured for 28 cylindrical specimens. The apparent modulus, yield and ultimate stress, and yield and ultimate strain each significantly differed (p<0.05) in the superior and inferior locations. Linear and power law relationships between superior and inferior mechanical properties and BMAD were determined. The inferior apparent modulus and stresses were higher than those in the superior locations. These results show that the press-fit fixation characteristics of the femoral knee component differ on the anterior shield and posterior condyles. This information will be useful in the assignment of mechanical properties in finite element models for further investigations of femoral knee components. The property–density relations also have applications for implant design and preoperative assessment of bone strength using clinically available tools.

Keywords: Cancellous bone; Distal femur; Apparent modulus; Bone mineral apparent density; Femoral knee components
Links

DOI: 10.1016/j.jbiomech.2007.11.018

PubMed: 18206893

WoS: 000254943800019

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2018	Zhao S, Arnold M, Ma S, Abel RL, Cobb JP, Hansen U, Boughton O. Standardizing compression testing for measuring the stiffness of human bone. Bone Joint Res. August 2018;7(8):524-538.
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2011	Yao H. Microstructure-Based Characterization and Modeling of Trabecular Bone Deformation and Failure [PhD thesis]. Southern Methodist University; August 3, 2011.
2020	Amromanoh OA. An Experimental Study of the Effect of Bone Inorganic-Organic Composition on the Mechanical Properties [Master's thesis]. Winnipeg, MB: University of Manitoba; April 2020.
2008	Burgers TA. Press-Fit Fixation and Viscoelastic Response of a Bone-Implant Interface in the Distal Femur [PhD thesis]. University of Wisconsin – Madison; 2008.
2016	Meyer LA. Testing and Modeling Mechanical Properties of Ex Vivo Trabecular Bone [PhD thesis]. University of Wisconsin – Madison; 2016.
2016	Alshaya AA. Experimental, Analytical and Numerical Analyses of Orthotropic Materials and Biomechanics Application [PhD thesis]. University of Wisconsin – Madison; 2016.