Dynamic compressive properties of human lumbar intervertebral joints:​ a comparison between fresh and thawed specimens

Smeathers, J. E.<sup>1</sup>; Joanes, D. N.<sup>1</sup>

Affiliations

¹Rheumatology and Rehabilitation Research Unit, University of Leeds

²Statistics Department, University of Leeds

Abstract

A comparison between the dynamic compressive properties of human lumbar intervertebral joints when fresh and after a period of deep frozen storage was made. Physiologically relevant loads of −750 ± 250 N were applied in axial compression with the joint constrained against bending, over a frequency range of 0.01–10 Hz. Frozen storage was found not to affect the compressive stiffness or hysteresis of the seven joints. The magnitude of the observed changes in mean values were small, less than 1% decrease in the compressive stiffness and less than 1% increase in hysteresis after deep frozen storage.

Links

DOI: 10.1016/0021-9290(88)90148-0

PubMed: 3417694

WoS: A1988P366800009

History

Received: 1986-07-15

Revised: 1987-03-31

Cited Works (15)

Year	Entry
1966	Viidik A, Lewin T. Changes in tensile strength characteristics and histology of rabbit ligaments induced by different modes of postmortal storage. Acta Orthop Scand. 1966;37(2):141-155.
1960	Nachemson A. Lumbar intradiscal pressure: experimental studies on post-mortem material. Acta Orthop Scand. 1960;31(suppl 43):1-104.
1957	Brown T, Hansen RJ, Yorra AJ. Some mechanical tests on the lumbosacral spine with particular reference to the intervertebral discs: a preliminary report. J Bone Joint Surg. October 1957;39A(5):1135-1164.
1966	Sedlin‌ ED, Hirsch C. Factors affecting the determination of the physical properties of femoral cortical bone. Acta Orthop Scand. 1966;37(1):29-48.
1955	Hirsch C. The reaction of intervertebral discs to compression forces. J Bone Joint Surg. December 1955;37A(6):1188-1196.
1986	Miller JAA, Schultz AB, Warwick DN, Spencer DL. Mechanical properties of lumbar spine motion segments under large loads. J Biomech. 1986;19(1):79-84.
1980	Adams MA, Hutton WC. The effect of posture on the role of the apophysial joints in resisting intervertebral compressive forces. J Bone Joint Surg. August 1980;62B(3):358-362.
1967	Galante JO. Tensile properties of the human lumbar annulus fibrosus. Acta Orthop Scand. 1967;(suppl 100):1-91.
1986	Koeller W, Muehlhaus S, Meier W, Hartmann F. Biomechanical properties of human intervertebral discs subjected to axial dynamic compression: influence of age and degeneration. J Biomech. 1986;19(10):807-816.
1968	Matthews LS, Ellis D. Viscoelastic properties of cat tendon: effects of time after death and preservation by freezing. J Biomech. July 1968;1(2):65-71.
1985	Panjabi MM, Krag M, Summers D, Videman T. Biomechanical time-tolerance of fresh cadaveric human spine specimens. J Orthop Res. 1985;3(3):292-300.
1979	Nachemson AL, Schultz AB, Berkson MH. Mechanical properties of human lumbar spine motion segments: influences of age, sex, disc level, and degeneration. Spine. January–February 1979;4(1):1-8.
1986	Panjabi MM, Summers DJ, Pelker RR, Videman T, Friedlaender GE, Southwick WO. Three-dimensional load-displacement curves due to forces on the cervical spine. J Orthop Res. 1986;4(2):152-161.
1972	Markolf KL. Deformation of the thoracolumbar intervertebral joints in response to external loads: a biomechanical study using autopsy material. J Bone Joint Surg. April 1972;54A(3):511-533.
1951	Virgin WJ. Experimental investigations into the physical properties of the intervertebral disc. J Bone Joint Surg. November 1951;33B(4):607-611.

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2007	Kemper A, McNally C, Manoogian S, McNeely D, Duma S. Stiffness properties of human lumbar intervertebral discs in compression and the influence of strain rate. In: Proceedings of the 20th International Technical Conference on the Enhanced Safety of Vehicles (ESV). June 18-21, 2007; Lyon, France.
2005	Stemper BD, Stineman MR, Yoganandan N, Pintar FA, Sinson GP, Gennarelli TA. Mechanical characterization of internal layer failure in the human carotid artery. In: Proceedings of the 2005 International IRCOBI Conference on the Biomechanics of Impact. September 21-23, 2005; Prague, Czech Republic.269-277.
2020	Ortiz-Paparoni MA, Pigue M, Bass CR‘. Building a whole spine from segments: lumbar spine response during dynamic compression. In: Proceedings of the 2020 International IRCOBI Conference on the Biomechanics of Injury. 2020; Munich, Germany.770-781.
1998	Van Ee CA, Chasse AL, Myers BS. The effect of postmortem time and freezer storage on the mechanical properties of skeletal muscle. In: Proceedings of the 42nd Stapp Car Crash Conference. November 2-4, 1998; Tempa, AZ. Warrendale, PA: Society of Automotive Engineers:169-. SAE 983155.
2017	Arun MWJ, Hadagali P, Driesslein K, Curry W, Yoganandan N, Pintar FA. Biomechanics of lumbar motion-segments in dynamic compression. Stapp Car Crash J. November 2017;61:1-25. SAE 2017-22-0001.
2001	Callaghan JP, McGill SM. Intervertebral disc herniation: studies on a porcine model exposed to highly repetitive flexion/extension motion with compressive force. Clin Biomech (Bristol, Avon). January 2001;16(1):28-37.
1991	Adams MA, Dolan P. A technique for quantifying the bending moment acting on the lumbar spine in vivo. J Biomech. 1991;24(2):117-126.
1991	Myers BS, McElhaney JH, Doherty BJ. The viscoelastic responses of the human cervical spine in torsion: experimental limitations of quasi-linear theory, and a method for reducing these effects. J Biomech. 1991;24(9):811-817.
1995	McCubbrey DA, Cody DD, Peterson EL, Kuhn JL, Flynn MJ, Goldstein SA. Static and fatigue failure properties of thoracic and lumbar vertebral bodies and their relation to regional density. J Biomech. August 1995;28(8):891-899.
2004	Walsh AJL, Lotz JC. Biological response of the intervertebral disc to dynamic loading. J Biomech. March 2004;37(3):329-337.
2000	Van Ee CA, Chasse AL, Myers BS. Quantifying skeletal muscle properties in cadaveric test specimens: effects of mechanical loading, postmortem time, and freezer storage. J Biomech Eng. February 2000;122(1):9-14.
1996	Nightingale RW, McElhaney JH, Richardson WJ, Best TM, Myers BS. Experimental impact injury to the cervical spine: relating motion of the head and the mechanism of injury. J Bone Joint Surg. March 1996;78A(3):412-421.
1995	Callaghan JP, McGill SM. Frozen storage increases the ultimate compressive load of porcine vertebrae. J Orthop Res. September 1995;13(5):809-812.
1991	Gordon SJ, Yang KH, Mayer PJ, Mace AH Jr, Kish VL, Radin EL. Mechanism of disc rupture: a preliminary report. Spine. April 1991;16(6):450-456.
2001	Dhillon N, Bass EC, Lotz JC. Effect of frozen storage on the creep behavior of human intervertebral discs. Spine. April 15, 2001;26(8):883-888.
2015	Oxland TR. A history of spine biomechanics: focus on 20th century progress. Unfallchirurg. December 2015;118(suppl 1):80-92.
1993	Nightingale RW. The Dynamics of Head and Cervical Spine Impact [PhD thesis]. Duke University; 1993.
2000	Van Ee CA. Tensile Properties of the Human Muscular and Ligamentous Cervical Spine [PhD thesis]. Duke University; 2000.
2022	Cotter TR. Development of a Real-Time Physics-Based Spinal Fusion Training Simulator for Lumbar Discectomy [PhD thesis]. McGill University; April 2022.
2018	Long RG. Repair of Herniated Intervertebral Discs: Designing and Translating Annulus Fibrosus Sealants [PhD thesis]. Icahn School of Medicine at Mount Sinai; 2018.
2002	Petit Y. Analyse biomécanique de la flexibilité du rachis scoliotique pour la planification de l'instrumentation chirurgicale [PhD thesis]. École polytechnique de Montréal; December 2002.
2011	Wagnac É. Expérimentation et modélisation détaillée de la colonne vertébrale pour étudier le rôle de facteurs anatomiques et biomécaniques sur les traumatismes rachidiens [PhD thesis]. École polytechnique de Montréal; November 2011.
2013	Van Toen CY. Biomechanics of Cervical Spine and Spinal Cord Injury Under Combined Axial Compression and Lateral Bending Loading [PhD thesis]. Vancouver, BC: University of British Columbia; December 2013.
2002	Walsh AJL. Tissue Remodeling in the Intervertebral Disc: Response to Dynamic Loading and Growth Factors [PhD thesis]. San Francisco, University of California; 2002.
2017	Berg-Johansen B. Characterization of the Spinal Disc-Vertebra Interface and Its Relation to Injury and Back Pain [PhD thesis]. San Francisco, University of California; 2017.
1993	McCubbrey DA. The Macroscopic Architectural Properties of Vertebral Trabecular Bone and Their Relation to Whole Vertebral Failure Loads [PhD thesis]. University of Michigan; 1993.
2000	Kerr DJ. A Mechanical Comparison of Multi-Segmental and Uni-Segmental Lumbar Porcine Spines in Flexion [Master's thesis]. University of Guelph; September 2000.
2002	Gillespie KA. Biomechanical Role of Lumbar Spine Ligaments in Flexion and Extension Using a Parallel Linkage Robot: A Porcine Model [Master's thesis]. University of Guelph; April 2002.
1990	Cholewicki J. The Contribution of the Lumbar Disc and Posterior Ligaments in Generating Trunk Extensor Moment During Extremely Heavy Lifts Using Fluoroscopy [Master's thesis]. University of Waterloo; 1990.
1997	Yingling VR. Shear Loading of the Lumbar Spine: Modulators of Motion Segment Tolerance and the Resulting Injuries [PhD thesis]. University of Waterloo; 1997.
1999	Callaghan JP. Low-Magnitude Loading of the Spine: In Vivo and in Vitro Studies [PhD thesis]. University of Waterloo; 1999.
2007	Scannell JP. In Vitro and in Vivo Biomechanical Investigation of the Clinical Practice of Disc Prolapse Prevention and Rehabilitation [PhD thesis]. University of Waterloo; 2007.
2008	Parkinson RJ. Refining the Relationship Between the Mechanical Demands on the Spine and Injury Mechanisms Through Improved Estimates of Load Exposure and Tissue Tolerance [PhD thesis]. University of Waterloo; 2008.
2011	Howarth SJ. Mechanical Response of the Porcine Cervical Spine to Acute and Repetitive Anterior-Posterior Shear [PhD thesis]. University of Waterloo; 2011.
2014	Gooyers CE. Exploring Interactions Between Force, Repetition and Posture on Low Back Joint Loading and Intervertebral Disc Injury [PhD thesis]. University of Waterloo; 2014.
2017	Levine IC. The Effects of Body Composition and Body Configuration on Impact Dynamics During Lateral Falls: Insights from in-Vivo, in-Vitro, and in-Silico Approaches [PhD thesis]. University of Waterloo; 2017.
2020	Fewster KM. Exploring Low to Moderate Velocity Motor Vehicle Rear Impacts as a Viable Injury Mechanism in the Lumbar Spine [PhD thesis]. University of Waterloo; 2020.