As an introduction to the general theme of the IRCOBI conference 1988 this paper describes some biomechanical issues where the application of biometric approaches is necessary. The following problem areas are dealt with: population at risk, random sampling for in-depth studies, injury probability models (probit, logit, Weibull) and establishing of protection criteria of dummies. The general aim of the paper is to increase the awareness of the significance for a more intensive cooperation between biomechanics and biostatistics.