Vehicle front-end geometry and stiffness characteristics have been shown to influence pedestrian lower extremity response and injury patterns. The goal of this study is to compare the lower extremity response and injuries of post mortem human surrogates (PMHS) tested in full-scale vehicle-pedestrian impact experiments with a small sedan and a large sport utility vehicle (SUV). The pelves and lower limbs of six PMHS were instrumented with six-degree-of-freedom instrumentation packages. The PMHS were then positioned laterally in mid-stance gait and subjected to vehicle impact at 40 km/h with either a small sedan (n=3) or a large SUV (n=3). Detailed descriptions of the pelvic and lower extremity injuries are presented in conjunction with global and local kinematics data and high speed video images. Injured PMHS knee joints reached peak lateral bending angles between 25 and 85 degrees (exceeding published injury criteria) at bending rates between 1.1 deg/ms and 3.7 deg/ms. In one case, the onset of tibia and fibula fracture may have prevented ipsilateral knee joint injury. Overall, the SUV appeared to be more aggressive than the sedan in causing injuries to the lower extremities and the pelvis of the tested PMHS.