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Diez‐Perez, Adolfo; Güerri, Roberto;
Nogues, Xavier
; Cáceres, Enric; Peña, Maria Jesus; Mellibovsky, Leonardo; Randall, Connor; Bridges, Daniel;
Weaver, James C.
; Proctor, Alexander; Brimer, Davis; Koester, Kurt J.;
Ritchie, Robert O.
;
Hansma, Paul K.
Microindentation for in vivo measurement of bone tissue mechanical properties in humans
J Bone Miner Res
. 2010;25(8):1877-1885
Keywords
Keywords:
bone; fracture; bone quality; instrument; clinical trials
Links
DOI:
10.1002/jbmr.73
PubMed:
20200991
WoS:
000281325000019
Cited Works (26)
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2009
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2008
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J Bone Miner Res
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2005
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Am J Med
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2004
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J Mater Chem
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2000
Garner P, Sornay-Rendu E, Claustrat B, Delmas PD. Biochemical markers of bone turnover, endogenous hormones and the risk of fractures in postmenopausal women: the OFELY study.
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J Biomech
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2005
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Nano Lett
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2006
Peterlik H, Roschger P, Klaushofer K, Fratzl P. From brittle to ductile fracture of bone.
Nat Mater
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2007
Thurner PJ, Erickson B, Jungmann R, Schriock Z, Weaver JC, Fantner GE, Schitter G, Morse DE, Hansma PK. High-speed photography of compressed human trabecular bone correlates whitening to microscopic damage.
Eng Fract Mech
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2007
Taylor D, Hazenberg JG, Lee TC. Living with cracks: damage and repair in human bone.
Nat Mater
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2004
Currey J. Incompatible mechanical properties in compact bone.
J Theo Biol
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2008
Koester KJ, Ager JW III, Ritchie RO. The true toughness of human cortical bone measured with realistically short cracks.
Nat Mater
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2006
Garnero P, Borel O, Gineyts E, Duboeuf F, Solberg H, Bouxsein ML, Christiansen C, Delmas PD. Extracellular post-translational modifications of collagen are major determinants of biomechanical properties of fetal bovine cortical bone.
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2006
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2003
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2002
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2005
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2007
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J R Soc Interface
. April 22, 2007;4(3):277-282.
2003
Bouxsein ML. Bone quality: where do we go from here?
Osteoporos Int
. September 2003;14(suppl 5):S118-S127.
Cited By (39)
Year
Entry
2015
Milovanovic P, Zimmermann EA, Riedel C, vom Scheidt A, Herzog L, Krause M, Djonic D, Djuric M, Püschel K, Amling M, Ritchie RO, Busse B. Multi-level characterization of human femoral cortices and their underlying osteocyte network reveal trends in quality of young, aged, osteoporotic and antiresorptive-treated bone.
Biomaterials
. March 2015;45:46-55.
2013
Gallant MA, Brown DM, Organ JM, Allen MR, Burr DB. Reference-point indentation correlates with bone toughness assessed using whole-bone traditional mechanical testing.
Bone
. March 2013;53(1):301-305.
2015
Katsamenis OL, Jenkins T, Thurner PJ. Toughness and damage susceptibility in human cortical bone is proportional to mechanical inhomogeneity at the osteonal-level.
Bone
. July 2015;76:158-168.
2016
Farr JN, Khosla S. Determinants of bone strength and quality in diabetes mellitus in humans.
Bone
. January 2016;82:28-34.
2016
Mirzaali MJ, Schwiedrzik JJ, Thaiwichai S, Best JP, Michler J, Zysset PK, Wolfram U. Mechanical properties of cortical bone and their relationships with age, gender, composition and microindentation properties in the elderly.
Bone
. December 2016;93:196-211.
2020
Rezaee T, Bouxsein ML, Karim L. Increasing fluoride content deteriorates rat bone mechanical properties.
Bone
. July 2020;136:115369.
2020
Taylor EA, Donnelly E. Raman and Fourier transform infrared imaging for characterization of bone material properties.
Bone
. October 2020;139:115490.
2016
Diez-Perez A, Bouxsein M, Eriksen E, Khosla S, Nyman J, Papapoulos S, Tang S. Technical note: recommendations for a standard procedure to assess cortical bone at the tissue-level in vivo using impact microindentation.
Bone Rep
. December 2016;5:181-185.
2021
Rajput S, Mehta P, Mittal M, Rajender S, Chattopadhyay N. Human relevance of preclinical studies on the skeletal impact of inflammatory bowel disease: a systematic review and meta-analysis.
Calcif Tiss Int
. June 2021;108(6):708-724.
2020
Mirzaali MJ, Libonati F, Böhm C, Rinaudo L, Cesana BM, Ulivieri FM, Vergani L. Fatigue-caused damage in trabecular bone from clinical, morphological and mechanical perspectives.
Int J Fatigue
. April 2020;133:105451.
2014
Farr JN, Drake MT, Amin S, Melton LJ III, McCready LK, Khosla S. In vivo assessment of bone quality in postmenopausal women with type 2 diabetes.
J Bone Miner Res
. April 2014;29(4):787-795.
2015
Granke M, Makowski AJ, Uppuganti S, Does MD, Nyman JS. Identifying novel clinical surrogates to assess human bone fracture toughness.
J Bone Miner Res
. July 2015;30(7):1290-1300.
2017
Nilsson AG, Sundh D, Johansson L, Nilsson M, Mellström D, Rudäng R, Zoulakis M, Wallander M, Darelid A, Lorentzon M. Type 2 diabetes mellitus is associated with better bone microarchitecture but lower bone material strength and poorer physical function in elderly women: a population‐based study.
J Bone Miner Res
. May 2017;32(5):1062-1071.
2021
Diniz‐Sousa F, Veras L, Boppre G, Sa‐Couto P, Devezas V, Santos‐Sousa H, Preto J, Vilas‐Boas JP, Machado L, Oliveira J, Fonseca H. The effect of an exercise intervention program on bone health after bariatric surgery: a randomized controlled trial.
J Bone Miner Res
. March 2021;36(3):489-499.
2022
Ahmed R, Uppuganti S, Derasari S, Meyer J, Pennings JS, Elefteriou F, Nyman JS. Identifying bone matrix impairments in a mouse model of neurofibromatosis type 1 (NF1) by clinically translatable techniques.
J Bone Miner Res
. August 2022;37(8):1603-1621.
2023
Hariri H, Kose O, Bezdjian A, Daniel SJ, St-Arnaud R. USP53 regulates bone homeostasis by controlling rankl expression in osteoblasts and bone marrow adipocytes.
J Bone Miner Res
. April 2023;38(4):578-596.
2016
Furst JR, Bandeira LC, Fan W-W, Agarwal S, Nishiyama KK, McMahon DJ, Dworakowski E, Jiang H, Silverberg SJ, Rubin MR. Advanced glycation endproducts and bone material strength in type 2 diabetes.
J Clin Endocrinol Metab
. June 2016;101(6):2502-2510.
2011
Jungmann R, Szabo ME, Schitter G, Tang RY-S, Vashishth D, Hansma PK, Thurner PJ. Local strain and damage mapping in single trabeculae during three-point bending tests.
J Mech Behav Biomed Mater
. May 2011;4(4):523-534.
2015
Poundarik AA, Wu P-C, Evis Z, Sroga GE, Ural A, Rubin M, Vashishth D. A direct role of collagen glycation in bone fracture.
J Mech Behav Biomed Mater
. December 2015;52:120-130.
2017
Sandino C, McErlain DD, Schipilow J, Boyd SK. Mechanical stimuli of trabecular bone in osteoporosis: a numerical simulation by finite element analysis of microarchitecture.
J Mech Behav Biomed Mater
. February 2017;66:19-27.
2023
Visser N, Rezaie E, Ducharme A, Shin AY, Bishop AT. The effect of surgical revascularization on the mechanical properties of cryopreserved bone allograft in a porcine tibia model.
J Orthop Res
. April 2023;41(4):815-822.
2020
Ballesta S, Güerri-Fernández RC, Chillarón JJ, Güell A, Herrera S, Torres E, Ascoeta NG, Le-Roux JAF, Díez A. The use of microindentation for the study of bone properties in type 1 diabetes mellitus patients.
Osteoporos Int
. January 2020;31(1):175-180.
2020
Starr JR, Tabacco G, Majeed R, Omeragic B, Bandeira L, Rubin MR. PTH and bone material strength in hypoparathyroidism as measured by impact microindentation.
Osteoporos Int
. February 2020;31(2):327-333.
2024
Szabo E.
Insights Into the Mechanical Behavior of Maturing Cortical Bone: A Porcine Model
[PhD thesis]. Cleveland, OH: Case Western Reserve University; May 2024.
2013
Kim G.
The Effects of Mineralization and Crystallinity on the Mechanical Behavior of Bone
[PhD thesis]. Ithaca, NY: Cornell University; May 2013.
2020
Taylor EA.
Validation and Implementation of Vibrational Spectroscopic Measures of Bone Composition
[PhD thesis]. Ithaca, NY: Cornell University; December 2020.
2016
Oei L.
Epidemiological, Radiological and Genetic Aspects of Endocrine Bone Diseases
[PhD thesis]. Erasmus University Rotterdam; December 14, 2016.
2020
Axelsson KF.
Aspects of Fracture Prevention: The Role of Fracture Liaison Services and Alendronate
[PhD thesis]. University of Gothenburg; 2020.
2013
Bart ZR.
Multi-Scale Analysis of Morphology, Mechanics, and Composition of Collagen in Murine Osteogenesis Imperfecta
[Master's thesis]. Indianapolis, IN: Purdue University; August 2013.
2015
Clauser CA.
In Vivo Tibial Loading of Healthy and Osteolathrytic Mice
[Master's thesis]. Indianapolis, IN: Purdue University; May 2015.
2016
Hammond MA.
The Influence of Collagen Crosslinking and Treadmill Exercise on the Mechanics, Composition, and Morphology of Bone At Multiple Length Scales
[PhD thesis]. Purdue University; May 2016.
2011
Karim L.
The Biomolecular Basis of Bone Fracture
[PhD thesis]. Troy, NY: Rensselaer Polytechnic Institute; November 2011.
2013
Poundarik A.
The Role of Non-Collagenous Proteins, in Particular, Osteocalcin and Osteopontin, in the Determination of Bone Matrix Quality
[PhD thesis]. Troy, NY: Rensselaer Polytechnic Institute; May 2013.
2015
Grover K.
Osteopenia Uncovered by Remodeling in Spatial Distribution of Elastic Moduli in Orthogonal Orientations: A Nanoindentation Study
[Master's thesis]. Stony Brook, NY: Stony Brook University; May 2015.
2012
Tjhia CKH.
Bone Quality of Patients With Atypical Fractures and Severely Suppressed Bone Turnover
[PhD thesis]. Davis, University of California; 2012.
2016
Jones DA.
Reference Point Indentation of Human Trabecular Bone Treated With Bisphosphonates for Varying Durations
[Master's thesis]. University of Kentucky; 2016.
2022
Rezaee T.
Effect of Clinically Relevant Alterations of Mineral and Protein on Bone Biomechanics
[PhD thesis]. University of Massachusetts at Dartmouth; May 2022.
2014
Makowski AJ.
Evaluation of Raman Spectroscopy for Fracture Resistance Assessment
[PhD thesis]. Nashville, TN: Vanderbilt University; December 2014.
2013
Tomlinson RE.
The Role of Angiogenesis in Osteogenic Mechanical Loading
[PhD thesis]. St. Louis, MO: Washington University in St. Louis; May 2013.