Computer modeling and simulation of human movement

Pandy, Marcus G.

Affiliations

¹Department of Kinesiology and Department of Biomedical Engineering, University of Texas at Austin, Austin, Texas 78712

Abstract and keywords

Recent interest in using modeling and simulation to study movement is driven by the belief that this approach can provide insight into how the nervous system and muscles interact to produce coordinated motion of the body parts. With the computational resources available today, large-scale models of the body can be used to produce realistic simulations of movement that are an order of magnitude more complex than those produced just 10 years ago. This chapter reviews how the structure of the neuromusculoskeletal system is commonly represented in a multijoint model of movement, how modeling may be combined with optimization theory to simulate the dynamics of a motor task, and how model output can be analyzed to describe and explain muscle function. Some results obtained from simulations of jumping, pedaling, and walking are also reviewed to illustrate the approach.

Keywords: joint; jumping; muscle coordination; musculoskeletal; pedaling; walking

Links

DOI: 10.1146/annurev.bioeng.3.1.245

PubMed: 11447064

WoS: 000170775500011

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2004	Oi N, Pandy MG, Myers BS, Nightingale RW, Chancey VC. Variation of neck muscle strength along the human cervical spine. Stapp Car Crash J. 2004;48:397-417. SAE 2004-22-0017.
2007	Erdemir A, McLean S, Herzog W, van den Bogert AJ. Model-based estimation of muscle forces exerted during movements. Clin Biomech (Bristol, Avon). February 2007;22(2):131-154.
2017	Fuchs RK, Kersh ME, Carballido-Gamio J, Thompson WR, Keyak JH, Warden SJ. Physical activity for strengthening fracture prone regions of the proximal femur. Curr Osteoporos Rep. February 2017;15(1):43-52.
2002	Zajac FE, Neptune RR, Kautz SA. Biomechanics and muscle coordination of human walking, I: introduction to concepts, power transfer, dynamics and simulations. Gait Post. December 2002;16(3):215-232.
2003	Zajac FE, Neptune RR, Kautz SA. Biomechanics and muscle coordination of human walking, II: lessons from dynamical simulations and clinical implications. Gait Post. February 2003;17(1):1-17.
2007	Delp SL, Anderson FC, Arnold AS, Loan P, Habib A, John CT, Guendelman E, Thelen DG. OpenSim: open-source software to create and analyze dynamic simulations of movement. IEEE Trans Biomed Eng. November 2007;54(11):1940-1950.
2005	Reinbolt JA, Schutte JF, Fregly BJ, Koh BI, Haftka RT, George AD, Mitchell KH. Determination of patient-specific multi-joint kinematic models through two-level optimization. J Biomech. March 2005;38(3):621-626.
2006	Liu MQ, Anderson FC, Pandy MG, Delp SL. Muscles that support the body also modulate forward progression during walking. J Biomech. 2006;39(14):2623-2630.
2008	Liu MQ, Anderson FC, Schwartz MH, Delp SL. Muscle contributions to support and progression over a range of walking speeds. J Biomech. November 14, 2008;41(15):3243-3252.
2010	Pandy MG, Lin Y-C, Kim HJ. Muscle coordination of mediolateral balance in normal walking. J Biomech. August 10, 2010;43(11):2055-2064.
2001	Anderson FC, Pandy MG. Dynamic optimization of human walking. J Biomech Eng. October 2001;123(5):381-390.
2006	Damsgaard M, Rasmussen J, Christensen ST, Surma E, de Zee M. Analysis of musculoskeletal systems in the AnyBody modeling system. Simul Model Pract Theory. November 2006;14(8):1100-1111.
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2008	Pal S. Explicit Finite Element Modeling of Joint Mechanics [PhD thesis]. University of Denver; August 2008.
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2016	Navacchia A. Multiscale Musculoskeletal Modeling of the Lower Limb to Perform Personalized Simulations of Movement [PhD thesis]. University of Denver; November 2016.
2018	Hume DR. Translating Data from the Laboratory Into Simulation: A Computational Framework for Subject-Specific Finite Element Musculoskeletal Simulation [PhD thesis]. University of Denver; August 2018.
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2014	Ellman R. Skeletal Adaptation to Reduced Mechanical Loading [PhD thesis]. Cambridge, MA: Massachusetts Institute of Technology; September 2014.
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2017	Schloemer SA. Differences in Lower Extremity Muscle Function and Coordination During Gait Between Older and Young Adults [PhD thesis]. The Ohio State University; 2017.
2011	Hast MW. Assessment of Total Knee Replacement Performance Using Muscle-Driven Dynamic Simulations [PhD thesis]. State College, PA: Pennsylvania State University; August 2011.
2014	Celik H. Predictive Gait Simulations for Investigation of Musculoskeletal Structure and Locomotor Function [PhD thesis]. State College, PA: Pennsylvania State University; August 2014.
2008	Liu MQ-M. Muscle Contributions to Support and Progression Over a Range of Walking Speeds [PhD thesis]. Stanford University; October 2008.
2002	Jinha A. Analyses of Muscle Force Predictions Based on Optimization [Master's thesis]. Calgary, AB: University of Calgary; May 2002.
2004	Kaya M. Coordination of Cat Hindlimb Muscles During Voluntary Movements [PhD thesis]. Calgary, AB: University of Calgary; February 2004.
2004	Scovil CY. The Viability of a 3D Forward Dynamic Model of Walking as a Research Tool to Enhance Clinical Understanding of Gait Abnormalities [PhD thesis]. Calgary, AB: University of Calgary; March 2004.
2012	Luo G. Limiting Factors for Curved Sprinting Performance [PhD thesis]. Calgary, AB: University of Calgary; September 2012.
2009	Xiao M. Computer Simulation of Human Walking: Model Sensitivity and Application to Stroke Gait [PhD thesis]. University of Delaware; 2009.
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