Measurement of the density of trabecular bone

Sharp, D. J.<sup>1</sup>; Tanner, K. E.<sup>1</sup>; Bonfield, W.<sup>1</sup>

Affiliations

¹Department of Materials, Queen Mary College, Mile End Road, London E1 4NS, U.K.

Abstract

Methods of assessing real and apparent trabecular bone density are discussed. A method of defatting trabecular bone using trichlorethylene in an ultrasound bath for 4 h followed by rehydration in distilled water under vacuum is described, and its effectiveness discussed.

Links

DOI: 10.1016/0021-9290(90)90032-X

PubMed: 2384496

WoS: A1990DP19600012

History

Revised: 1989-10-09

Cited Works (8)

Year	Entry
1960	Arnold JS. Quantitation of mineralization of bone as an organ and tissue in osteoporosis. Clin Orthop Relat Res. 1960;17:167-175.
1967	Arnold JS, Tont SA. Bone water studied by differential centrifugation. Calcif Tiss Res. 1967;1(1):68-74.
1983	Ashby MF. The mechanical properties of cellular solids. Metall Trans. September 1983;A14:1755-1769.
1977	Carter DR, Hayes WC. The compressive behavior of bone as a two-phase porous structure. J Bone Joint Surg. 1977;59A(7):954-962.
1970	Galante J, Rostoker W, Ray RD. Physical properties of trabecular bone. Calcif Tiss Res. 1970;5(1):236-246.
1974	Behrens JC, Walker PS, Shoji H. Variations in strength and structure of cancellous bone at the knee. J Biomech. 1974;7(3):201-207.
1970	McElhaney JH, Fogle JL, Melvin JW, Haynes RR, Roberts VL, Alem NM. Mechanical properties of cranial bone. J Biomech. 1970;3(5):495-511.
1988	Rice JC, Cowin SC, Bowman JA. On the dependence of the elasticity and strength of cancellous bone on apparent density. J Biomech. 1988;21(2):155-168.

Cited By (25)

Year	Entry
1994	Linde F. Elastic and viscoelastic properties of trabecular bone by a compression testing approach. Dan Med Bull. April 1994;41(2):119-138.
2000	Ding M. Age variations in the properties of human tibial trabecular bone and cartilage. Acta Orthop Scand. 2000;71(suppl 292):1-45.
2018	Xie S, Wallace RJ, Callanan A, Pankaj P. From tension to compression: asymmetric mechanical behaviour of trabecular bone’s organic phase. Ann Biomed Eng. June 2018;46(6):801-809.
2008	Helgason B, Perilli E, Schileo E, Taddei F, Brynjólfsson S, Viceconti M. Mathematical relationships between bone density and mechanical properties: a literature review. Clin Biomech (Bristol, Avon). 2008;23(2):135-146.
2005	Shim VPW, Yang LM, Liu JF, Lee VS. Characterisation of the dynamic compressive mechanical properties of cancellous bone from the human cervical spine. Int J Impact Eng. December 2005;32(1-4):525-540.
1994	Keller TS. Predicting the compressive mechanical behavior of bone. J Biomech. September 1994;27(9):1159-1168.
1999	Ding M, Odgaard A, Hvid I. Accuracy of cancellous bone volume fraction measured by micro-CT scanning. J Biomech. 1999;32(3):323-326.
2007	Lievers WB, Lee V, Arsenault SM, Waldman SD, Pilkey AK. Specimen size effect in the volumetric shrinkage of cancellous bone measured at two levels of dehydration. J Biomech. 2007;40(9):1903-1909.
2008	Zioupos P, Cook RB, Hutchinson JR. Some basic relationships between density values in cancellous and cortical bone. J Biomech. 2008;41(9):1961-1968.
1997	Ding M, Dalstra M, Danielsen CC, Kabel J, Hvid I, Linde F. Age variations in the properties of human tibial trabecular bone. J Bone Joint Surg. November 1997;79B(6):995-1002.
2002	Ding M, Odgaard A, Danielsen CC, Hvid I. Mutual associations among microstructural, physical and mechanical properties of human cancellous bone. J Bone Joint Surg. August 2002;84B(6):900-907.
2020	Xie S, Wallace RJ, Pankaj P. Time-dependent behaviour of demineralised trabecular bone: experimental investigation and development of a constitutive model. J Mech Behav Biomed Mater. September 2020;109:103751.
1994	Spadaro JA, Werner FW, Brenner RA, Fortino MD, Fay LA, Edwards WT. Cortical and trabecular bone contribute strength to the osteopenic distal radius. J Orthop Res. March 1994;12(2):211-218.
2010	Lievers WB, Poljsak AS, Waldman SD, Pilkey AK. Effects of dehydration-induced structural and material changes on the apparent modulus of cancellous bone. Med Eng Phys. 2010;32(8):921-925.
2004	Wegst UGK, Ashby MF. The mechanical efficiency of natural materials. Philos Mag. July 21, 2004;84(21):2167-2181.
2003	Bredbenner TL. Damage Modeling of Vertebral Trabecular Bone [PhD thesis]. Cleveland, OH: Case Western Reserve University; January 2003.
2004	Samuel SP. Fluid/solid Interactions in Cancellous Bone [PhD thesis]. Cleveland State University; August 2004.
2018	Xie S. Characterisation of Time-Dependent Mechanical Behaviour of Trabecular Bone and Its Constituents [PhD thesis]. Edinburgh, Scotland: University of Edinburgh; 2018.
2011	Ahmed F. Multiscale Quantitative Imaging of Human Femoral Heads Using X-Ray Microtomography [PhD thesis]. Queen Mary University of London; 2011.
2009	Lievers WB. Effects of Geometric and Material Property Changes on the Apparent Elastic Properties of Cancellous Bone [PhD thesis]. Queen's University; April 2009.
2019	Heney AP. Effect of Fatigue-Induced Microdamage on the Compressive Properties of Bovine Trabecular Bone [Master's thesis]. Queen's University; September 2019.
2001	Lin W. Development of Quantitative Ultrasound to Determine the Physical Properties of Bone [PhD thesis]. Stony Brook, NY: State University of New York at Stony Brook; May 2001.
2004	Mittra ES. Assessment of Trabecular Bone Quality Using Microstructure, Micro-Mechanics and Micro-Finite Element Modeling [PhD thesis]. Stony Brook, NY: Stony Brook University; May 2004.
2002	Graham JH. Fracture Toughness Testing of the Trabecular Bone/acrylic Bone Cement Interface [PhD thesis]. Berkeley, CA: Berkeley, University of California; 2002.
2019	Martig S. Compressive Fatigue Life and Micromorphology of Equine Metacarpal Subchondral Bone [PhD thesis]. University of Melbourne; June 2019.