Assessment of bone tissue mineralization by conventional x-ray microcomputed tomography:​ comparison with synchrotron radiation microcomputed tomography and ash measurements

Kazakia, G. J.; Burghardt, A. J.; Cheung, S.; Majumdar, S.

Year	Entry
2018	Wu D, Isaksson P, Ferguson SJ, Persson C. Young’s modulus of trabecular bone at the tissue level: a review. Acta Biomater. September 15, 2018;78:1.
2009	Garrison JG, Slaboch CL, Niebur GL. Density and architecture have greater effects on the toughness of trabecular bone than damage. Bone. May 2009;44(5):924-929.
2009	Meganck JA, Kozloff KM, Thornton MM, Broski SM, Goldstein SA. Beam hardening artifacts in micro-computed tomography scanning can be reduced by X-ray beam filtration and the resulting images can be used to accurately measure BMD. Bone. December 2009;45(6):1104-1116.
2010	Easley SK, Jekir MG, Burghardt AJ, Li M, Keaveny TM. Contribution of the intra-specimen variations in tissue mineralization to pth- and raloxifene-induced changes in stiffness of rat vertebrae. Bone. April 2010;46(4):1162-1169.
2021	Vahidi G, Rux C, Sherk VD, Heveran CM. Lacunar-canalicular bone remodeling: impacts on bone quality and tools for assessment. Bone. February 2021;143:115663.
2021	Akhter MP, Recker RR. High resolution imaging in bone tissue research-review. Bone. February 2021;143:115620.
2022	Rux CJ, Vahidi G, Darabi A, Cox LM, Heveran CM. Perilacunar bone tissue exhibits sub-micrometer modulus gradation which depends on the recency of osteocyte bone formation in both young adult and early-old-age female C57Bl/6 mice. Bone. April 2022;157:116327.
2023	Palanca M, Cavazzoni G, Dall'Ara E. The role of bone metastases on the mechanical competence of human vertebrae. Bone. August 2023;173:116814.
2011	Donnelly E. Methods for assessing bone quality: a review. Clin Orthop Relat Res. August 2011;469:2128-2138.
2011	Burghardt AJ, Link TM, Majumdar S. High-resolution computed tomography for clinical imaging of bone microarchitecture. Clin Orthop Relat Res. August 2011;469:2179-2193.
2012	Gross T, Pahr DH, Peyrin F, Zysset PK. Mineral heterogeneity has a minor influence on the apparent elastic properties of human cancellous bone: SRμCT-based finite element study. Comput Methods Biomech Biomed Eng. November 2012;15(11):1137-1144.
2011	Tassani S, Öhman C, Baruffaldi F, Baleani M, Viceconti M. Volume to density relation in adult human bone tissue. J Biomech. 2011;44(1):103-108.
2011	Garrison JG, Gargac JA, Niebur GL. Shear strength and toughness of trabecular bone are more sensitive to density than damage. J Biomech. November 10, 2011;44(16):2747-2754.
2015	Kaynia N, Soohoo E, Keaveny TM, Kazakia GJ. Effect of intraspecimen spatial variation in tissue mineral density on the apparent stiffness of trabecular bone. J Biomech Eng. January 2015;137(1):011010.
2010	Bouxsein ML, Boyd SK, Christiansen BA, Guldberg RE, Jepsen KJ, Müller R. Guidelines for assessment of bone microstructure in rodents using micro-computed tomography. J Bone Miner Res. July 2010;25(7):1468-1486.
2018	Oliviero S, Giorgi M, Dall'Ara E. Validation of finite element models of the mouse tibia using digital volume correlation. J Mech Behav Biomed Mater. October 2018;86:172-184.
2009	Slyfield CR Jr, Niemeyer KE., Tkachenko EV, Tomlinson RE, Steyer GG, Patthanacharoenphon CG, Kazakia GJ, Wilson DL, Hernandez CJ. Three-dimensional surface texture visualization of bone tissue through epifluorescence-based serial block face imaging. J Microsc (Oxford). October 2009;236(1):52-59.
2019	Oliviero S, Giorgi M, Laud PJ, Dall’Ara E. Effect of repeated in vivo microCT imaging on the properties of the mouse tibia. PLoS One. November 21, 2019;14(11):e0225127.
2011	Cotter MM. Gross Morphology, Microarchitecture, Strength and Evolution of the Hominoid Vertebral Body [PhD thesis]. Cleveland, OH: Case Western Reserve University; May 2011.
2016	Wang J. Plate-Rod Microstructural Modeling for Accurate and Fast Assessment of Bone Strength [PhD thesis]. Columbia University; 2016.
2012	Slyfield CR Jr. The Biomechanics of Bone Turnover [PhD thesis]. Ithaca, NY: Cornell University; January 2012.
2015	Brock GR Jr. Changes in Bone Tissue Properties With Osteoporosis Treatment [PhD thesis]. Ithaca, NY: Cornell University; January 2015.
2021	Törnquist E. Bone Structure Characterisation Using Neutron Scattering Techniques [PhD thesis]. Lund, Sweden: Lund University; 2021.
2014	Jameson JR. Characterization of Bone Material Properties and Microstructure in Osteogenesis Imperfecta/brittle Bone Disease [PhD thesis]. Marquette University; December 2014.
2010	Deuerling JM. Effects of Ultrastructural Organization on the Mechanical Properties and Anisotropy of Human Cortical Bone [PhD thesis]. University of Notre Dame; December 2010.
2011	Garrison JG. The Relative Importance of Stress State, Microarchitecture, and Damage Burden in the Failure Behavior of Trabecular Bone [PhD thesis]. University of Notre Dame; April 2011.
2012	Zhao Y. Bone Indentation Modeling Via Analytical and Finite Element Methods [PhD thesis]. University of Notre Dame; March 2012.
2017	Kreipke TC. Structural, Mechanical, and Biological Relationships of Trabecular Bone in Osteoporosis [PhD thesis]. University of Notre Dame; April 2017.
2009	Lievers WB. Effects of Geometric and Material Property Changes on the Apparent Elastic Properties of Cancellous Bone [PhD thesis]. Queen's University; April 2009.
2016	Chen Y. Verification and Validation of MicroCT-Based Finite Element Models of Bone Tissue Biomechanics [PhD thesis]. Sheffield, UK: University of Sheffield; July 2016.
2019	Oliviero S. Non-Invasive Prediction of Bone Mechanical Properties of the Mouse Tibia in Longitudinal Preclinical Studies [PhD thesis]. University of Sheffield; January 2019.
2014	Gross T. Development and Application of 3d CT Image-Based Micro and Macro Finite Element Models for Human Bones and Orthopedic Implant Systems [PhD thesis]. Vienna University of Technology; 2014.
2021	Frank M. Mechanical Characterization of Individual Trabeculae [PhD thesis]. Vienna University of Technology; February 2021.
2010	Rodriguez AG. Human Endplate Permeability and Microstructure and Their Relationship to Disc Degeneration [PhD thesis]. San Francisco, University of California; 2010.
2010	Meganck JA. Fracture Healing and Regeneration in the Context of an Altered Collagenous Extracellular Matrix [PhD thesis]. University of Michigan; 2010.
2015	Hoy CFO. Cardiovascular Computed Tomography Phantom Fabrication and Characterization Through the Tailored Properties of Polymeric Composites and Cellular Foams [Master's thesis]. University of Toronto; November 2015.

Year	Entry
2002	Nuzzo S, Peyrin F, Cloetens P, Baruchel J, Boivin G. Quantification of the degree of mineralization of bone in three dimensions using synchrotron radiation microtomography. Med Phys. November 2002;29(11):2672-2681.
2002	Boivin G, Meunier PJ. The degree of mineralization of bone tissue measured by computerized quantitative contact microradiography. Calcif Tiss Int. June 2002;70(6):503-511.
1999	Ding M, Odgaard A, Hvid I. Accuracy of cancellous bone volume fraction measured by micro-CT scanning. J Biomech. 1999;32(3):323-326.
1996	Rüegsegger P, Koller B, Müller R. A microtomographic system for the nondestructive evaluation of bone architecture. Calcif Tiss Int. 1996;58(1):24-29.
1985	Kleerekoper M, Villanueva AR, Stanciu J, Rao DS, Parfitt AM. The role of three-dimensional trabecular microstructure in the pathogenesis of vertebral compression fractures. Calcif Tiss Int. 1985;37(6):594-597.
1999	Zysset PK, Guo XE, Hoffler CE, Moore KE, Goldstein SA. Elastic modulus and hardness of cortical and trabecular bone lamellae measured by nanoindentation in the human femur. J Biomech. October 1999;32(10):1005-1012.
1997	Laib A, Hildebrand T, Häuselmann HJ, Rüegsegger P. Ridge number density: a new parameter for in vivo bone structure analysis. Bone. December 1997;21(6):541-546.
2005	Borah B, Ritman EL, Dufresne TE, Jorgensen SM, Liu S, Sacha J, Phipps RJ, Turner RT. The effect of risedronate on bone mineralization as measured by micro-computed tomography with synchrotron radiation: correlation to histomorphometric indices of turnover. Bone. July 2005;37(1):1-9.
1997	Bloebaum RD, Skedros JG, Vajda EG, Bachus KN, Constantz BR. Determining mineral content variations in bone using backscattered electron imaging. Bone. May 1997;20(5):485-490.
2004	Mulder L, Koolstra JH, Van Eijden TMGJ. Accuracy of microCT in the quantitative determination of the degree and distribution of mineralization in developing bone. Acta Radiol. November 2004;45(7):769-777.
1994	Müller R, Hildebrand T, Rüegsegger P. Non-invasive bone biopsy: a new method to analyse and display the three-dimensional structure of trabecular bone. Phys Med Biol. January 1994;39(1):145-164.
1998	Gordon CL, Lang TF, Augat P, Genant HK. Image-based assessment of spinal trabecular bone structure from high-resolution CT images. Osteoporos Int. August 1998;8(4):317-325.
1991	Ciarelli MJ, Goldstein SA, Kuhn JL, Cody DD, Brown MB. Evaluation of orthogonal mechanical properties and density of human trabecular bone from the major metaphyseal regions with materials testing and computed tomography. J Orthop Res. May 1991;9(5):674-682.
1997	Meunier PJ, Boivin G. Bone mineral density reflects bone mass but also the degree of mineralization of bone: therapeutic implications. Bone. November 1997;21(5):373-377.
1993	Boyce TM, Bloebaum RD. Cortical aging differences and fracture implications for the human femoral neck. Bone. September–October 1993;14(5):769-778.
1999	Rho JY, Zioupos P, Currey JD, Pharr GM. Variations in the individual thick lamellar properties within osteons by nanoindentation. Bone. September 1999;25(3):295-300.
2002	Jaasma MJ, Bayraktar HH, Niebur GL, Keaveny TM. Biomechanical effects of intraspecimen variations in tissue modulus for trabecular bone. J Biomech. 2002;35(2):237-246.
1997	Hildebrand T, Rüegsegger P. A new method for the model-independent assessment of thickness in three-dimensional images. J Microsc (Oxford). 1997;185(1):67-75.
1970	Galante J, Rostoker W, Ray RD. Physical properties of trabecular bone. Calcif Tiss Res. 1970;5(1):236-246.
1998	Müller R, Van Campenhout H, Van Damme B, Van der Perre G, Dequeker J, Hildebrand T, Rüegsegger P. Morphometric analysis of human bone biopsies: a quantitative structural comparison of histological sections and micro-computed tomography. Bone. July 1998;23(1):59-66.
1989	Feldkamp LA, Goldstein SA, Parfitt MA, Jesion G, Kleerekoper M. The direct examination of three‐dimensional bone architecture in vitro by computed tomography. J Bone Miner Res. 1989;4(1):3-11.
1996	Courtney AC, Hayes WC, Gibson LJ. Age-related differences in post-yield damage in human cortical bone: experiment and model. J Biomech. November 1996;29(11):1463-1471.
2002	Riggs BL, Melton LJ III. Bone turnover matters: the raloxifene treatment paradox of dramatic decreases in vertebral fractures without commensurate increases in bone density. J Bone Miner Res. January 2002;17(1):11-14.