The biology of fracture healing in long bones

McKibbin, B.

Year	Entry
1992	Dunham J. Metabolism of the fracture callus. In: Hall BK, ed. Bone. Volume 5: Fracture Repair and Regeneration. Boca Raton, FL: Inc., CRC Press; 1992:1-31.
1992	Ashhurst DE. Macromolecular synthesis and mechanical stability during fracture repair. In: Hall BK, ed. Bone. Volume 5: Fracture Repair and Regeneration. Boca Raton, FL: Inc., CRC Press; 1992:61-121.
1992	Hall BK. Historical overview of studies on bone growth and repair. In: Hall BK, ed. Bone. Volume 6: Bone Growth — A. Boca Raton, FL: Inc., CRC Press; 1992:1-19.
2001	Majeska RJ. Cell biology of bone. In: Cowin SC, ed. Bone Mechanics Handbook. 2nd ed. Boca Raton, FL: CRC Press; 2001:2-1–2-24.
2001	Prendergast PJ, van der Meulen MCH. Mechanics of bone regeneration. In: Cowin SC, ed. Bone Mechanics Handbook. 2nd ed. Boca Raton, FL: CRC Press; 2001:32-1–32-13.
2005	Claes LE, Ito K. Biomechanics of fracture fixation and fracture healing. In: Mow VC, Huiskes R, eds. Basic Orthopaedic Biomechanics & Mechano-Biology. 3rd ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2005:563-584.
2001	Hausman MR, Schaffler MB, Majeska RJ. Prevention of fracture healing in rats by an inhibitor of angiogenesis. Bone. December 2001;29(6):560-564.
2022	Anani T, Castillo AB. Mechanically-regulated bone repair. Bone. January 2022;154:116223.
1992	Frost HM, Jee WSS. On the rat model of human osteopenias and osteoporoses. Bone Miner. September 1992;18(3):227-236.
1998	Einhorn TA. The cell and molecular biology of fracture healing. Clin Orthop Relat Res. October 1998;355(suppl):S7-S21.
1998	Claes LE, Heigele CA, Neidlinger-Wilke C, Kaspar D, Seidl W, Margevicius KJ, Augat P. Effects of mechanical factors on the fracture healing process. Clin Orthop Relat Res. October 1998;355(suppl):S132-S147.
2005	Hill TP, Später D, Taketo MM, Birchmeier W, Hartmann C. Canonical Wnt/β-catenin signaling prevents osteoblasts from differentiating into chondrocytes. Dev Cell. May 2005;8(5):727-738.
2004	Doblaré M, García JM, Gomez MJ. Modelling bone tissue fracture and healing: a review. Eng Fract Mech. September 2004;71(13-14):1809-1840.
2008	Shapiro F. Bone development and its relation to fracture repair: the role of mesenchymal osteoblasts and surface osteoblasts. Eur Cell Mater. 2008;15:53-76.
2020	Haffner-Luntzer M, Ignatius A. Animal models for studying metaphyseal bone fracture healing. Eur Cell Mater. July–December 2020;40:172-188.
1999	Claes LE, Heigele CA. Magnitudes of local stress and strain along bony surfaces predict the course and type of fracture healing. J Biomech. March 1999;32(3):255-266.
2000	Gardner TN, Stoll T, Marks L, Mishra S, Knothe Tate M. The influence of mechanical stimulus on the pattern of tissue differentiation in a long bone fracture: an FEM study. J Biomech. April 2000;33(4):415-425.
2002	Lacroix D, Prendergast PJ. A mechano-regulation model for tissue differentiation during fracture healing: analysis of gap size and loading. J Biomech. September 2002;35(9):1163-1171.
1998	Yoo JU, Barthel TS, Nishimura K, Solchaga L, Caplan AI, Goldberg VM, Johnstone B. The chondrogenic potential of human bone-marrow-derived mesenchymal progenitor cells. J Bone Joint Surg. December 1998;80A(12):1745-1757.
1985	Goodship AE, Kenwright J. The influence of induced micromovement upon the healing of experimental tibial fractures. J Bone Joint Surg. 1985;67B(4):650-655.
1997	Guldberg RE, Caldwell NJ, Guo XE, Goulet RW, Hollister SJ, Goldstein SA. Mechanical stimulation of tissue repair in the hydraulic bone chamber. J Bone Miner Res. August 1997;12(8):1295-1302.
1999	Barnes GL, Kostenuik PJ, Gerstenfeld LC, Einhorn TA. Growth factor regulation of fracture repair. J Bone Miner Res. November 1999;14(11):1805-1815.
1989	Blenman PR, Carter DR, Beaupré GS. Role of mechanical loading in the progressive ossification of a fracture callus. J Orthop Res. 1989;7(3):398-407.
1991	Cheal EJ, Mansmann KA, Digioia AM III, Hayes WC, Perren SM. Role of interfragmentary strain in fracture healing: ovine model of a healing osteotomy. J Orthop Res. January 1991;9(1):131-142.
1997	Claes L, Augat P, Suger G, Wilke H-J. Influence of size and stability of the osteotomy gap on the success of fracture healing. J Orthop Res. July 1997;15(4):577-584.
2002	Lacroix D, Prendergast PJ, Li G, Marsh D. Biomechanical model to simulate tissue differentiation and bone regeneration: application to fracture healing. Med Biol Eng Comput. January 2002;40(1):14-21.
2012	Claes L, Recknagel S, Ignatius A. Fracture healing under healthy and inflammatory conditions. Nat Rev Rheumatol. March 2012;8(3):133-143.
2007	Fratzl P, Weinkamer R. Nature’s hierarchical materials. Prog Mater Sci. November 2007;52(8):1263-1334.
2011	Leong PL. Spatial Localization of Mechanical Stimuli and Cellular Responses During Bone Healing in Vivo [PhD thesis]. Boston University; 2011.
2012	Hayward LNM. Investigations Into the Quantitative Relationship Between the Mechanical Environment and Skeletal Healing [PhD thesis]. Boston University; 2012.
1992	Ryaby JT. Biochemical Effects of Low-Frequency Electromagnetic Fields on Cells [PhD thesis]. New York, NY: The City University of New York; 1992.
2005	Murray AW. Fracture Healing in Osteopenic Bone and the Influence of Simvastatin [MD thesis]. Edinburgh, Scotland: University of Edinburgh; 2005.
2019	Lang A. HIF-Stabilization to Accelerate Fracture Healing: Evaluation of a New Therapeutic Strategy to Treat Delayed Bone Regeneration [PhD thesis]. The Free University of Berlin; 2019.
2007	Duvall CL. The Role of Osteopontin in Postnatal Vascular Growth: Functional Effects in Ischemic Limb Collateral Vessel Formation and Long Bone Fracture Healing [PhD thesis]. Atlanta, GA: Georgia Institute of Technology; May 2007.
2009	Kolambkar YM. Electrospun Nanofiber Meshes for the Functional Repair of Bone Defects [PhD thesis]. Atlanta, GA: Georgia Institute of Technology; December 2009.
2015	Allen AB. Modulation of Stem Cell Delivery Strategy by Platelet Lysate Utilization and Cell Aggregation for Enhanced Bone Regeneration [PhD thesis]. Atlanta, GA: Georgia Institute of Technology; August 2015.
2019	Klosterhoff BS. Mechanobiological Regulation of Early Stage Bone Repair [PhD thesis]. Atlanta, GA: Georgia Institute of Technology; August 2019.
2007	Geris L. Mathematical Modelling of Bone Regeneration During Fracture Healing and Implant Osseointegration [PhD thesis]. Katholieke Universiteit Leuven; May 2007.
2019	Ghiasi MS. Mechanobiological Modeling on Bone Fracture Healing [PhD thesis]. Northeastern University; December 2019.
2013	Weiss HE. Engineering a Replacement Bone Tissue With Adult Adipose-Derived Stem Cells [PhD thesis]. University of Notre Dame; April 2013.
2020	Karali A. Multi-Scale Evaluation of Bone Combining Indentation, in Situ XCT Mechanics and Digital Volume Correlation [PhD thesis]. Portsmouth, England: University of Portsmouth; 2020.
1990	Fyhrie PB. Finite Element Analyses of Fracture Healing in Long Bones [PhD thesis]. Stanford University; August 10, 1990.
2018	Bobyn JD. Improving Outcomes in NF1 Spine Fusion [PhD thesis]. University of Sydney; 2018.
2008	Byrne DP. Computational Modelling of Bone Regeneration Using a Three-Dimensional Lattice Approach [PhD thesis]. Trinity College Dublin; October 2008.
2007	Isaksson HE. Mechanical and Mechanobiological Influences on Bone Fracture Repair: Identifying Important Cellular Characteristics [PhD thesis]. Eindhoven, The Netherlands: Eindhoven University of Technology; 2007.
2003	Youn I. Osteogenic Properties of the Periosteum: In Vitro Characterizations and Its Potential Application to Bone-Tunnel Healing [PhD thesis]. Tulane University; 2003.
2016	Yu Q. Applications of Human Bone Materials and Synthesized Biomaterials for Bone-Related Tissue Engineering [PhD thesis]. University of Akron; December 2016.
2005	Ashe MC. Upper Limb Bone Health: Cadaveric, Imaging and Clinical Studies With Special Emphasis on Peripheral Quantitative Computed Tomography [PhD thesis]. Vancouver, BC: University of British Columbia; April 2005.
2013	Soicher MA. Fabrication and Characterization of Remineralized Bone Matrices (RBM) for Use as Bone Tissue Engineering Substrates [PhD thesis]. Davis, University of California; 2013.
1995	Guldberg RE. Mechanical Adaptation of Trabecular Bone Formation in Vivo [PhD thesis]. University of Michigan; 1995.
1995	Waanders NA. A Distraction Osteogenesis Model to Investigate the Influence of the Mechanical Environment on Bone Formation [PhD thesis]. University of Michigan; 1995.
1996	Germiller JA. Influence of Skeletal Muscle on Embryonic Long Bone Development [PhD thesis]. University of Michigan; 1996.
1996	Rouleau JP. The Influence of Cyclic Strain Amplitude and Timing of Mechanical Stimulation on Secondary Fracture Healing [PhD thesis]. University of Michigan; 1996.
2008	Weaver AS. The Effect of Mechanical Stimulation on Bone Fracture Healing: Changes in Callus Morphology and Mesenchymal Stem Cell Homing [PhD thesis]. University of Michigan; 2008.
2000	Simmons CA. Modelling and Characterization of Mechanically Regulated Tissue Formation Around Bone-Interfacing Implants [PhD thesis]. University of Toronto; 2000.
2011	Kempen DHR. Bone Regeneration Based on Growth Factor Releasing Polymer Composites [PhD thesis]. Utrecht University; 2011.

Year	Entry
1957	Fukada E, Yasuda I. On the piezoelectric effect of bone. J Phys Soc Jpn. October 1957;12(10):1158-1162.
1962	Bassett CAL, Becker RO. Generation of electric potentials by bone in response to mechanical stress. Science. September 28, 1962;137(3535):1063.