Growth factor regulation of fracture repair

Barnes, George L.; Kostenuik, Paul J.; Gerstenfeld, Louis C.; Einhorn, Thomas A.

Affiliations

¹Musculoskeletal Research Laboratory, Department of Orthopaedic Surgery, Boston University School of Medicine, Boston, Massachusetts, U.S.A.

Links

DOI: 10.1359/jbmr.1999.14.11.1805

PubMed: 10571679

WoS: 000083368600001

Cited Works (4)

Year	Entry
1998	Einhorn TA. The cell and molecular biology of fracture healing. Clin Orthop Relat Res. October 1998;355(suppl):S7-S21.
1992	Yasko AW, Lane JM, Fellinger EJ, Wozney JM, Wang EA. The healing of segmental bone defects, induced by recombinant human bone morphogenetic protein (rhBMP-2): a radiographic, histological, and biomechanical study in rats. J Bone Joint Surg. June 1992;74A(5):659-670.
1978	McKibbin B. The biology of fracture healing in long bones. J Bone Joint Surg. May 1978;60B(2):150-162.
1965	Urist MR. Bone: formation by autoinduction. Science. November 12, 1965;150(3698):893-899.

Cited By (25)

Year	Entry
2001	Jee WSS. Integrated bone tissue physiology: anatomy and physiology. In: Cowin SC, ed. Bone Mechanics Handbook. 2nd ed. Boca Raton, FL: CRC Press; 2001:1-1–1-68.
2001	Prendergast PJ, van der Meulen MCH. Mechanics of bone regeneration. In: Cowin SC, ed. Bone Mechanics Handbook. 2nd ed. Boca Raton, FL: CRC Press; 2001:32-1–32-13.
2001	Hausman MR, Schaffler MB, Majeska RJ. Prevention of fracture healing in rats by an inhibitor of angiogenesis. Bone. December 2001;29(6):560-564.
2008	Shapiro F. Bone development and its relation to fracture repair: the role of mesenchymal osteoblasts and surface osteoblasts. Eur Cell Mater. 2008;15:53-76.
2011	Marsell R, Einhorn TA. The biology of fracture healing. Injury. June 2011;42(6):551-555.
2002	Lieberman JR, Daluiski A, Einhorn TA. The role of growth factors in the repair of bone: biology and clinical applications. J Bone Joint Surg. June 2002;84A(6):1032-1044.
2001	Kon T, Cho T-J, Aizawa T, Yamazaki M, Nooh N, Graves D, Gerstenfeld LC, Einhorn TA. Expression of osteoprotegerin, receptor activator of NF-κB ligand (osteoprotegerin ligand) and related proinflammatory cytokines during fracture healing. J Bone Miner Res. June 2001;16(6):1004-1014.
2003	Gerstenfeld LC, Cullinane DM, Barnes GL, Graves DT, Einhorn TA. Fracture healing as a post‐natal developmental process: molecular, spatial, and temporal aspects of its regulation. J Cell Biochem. April 2003;88(5):873-884.
2004	Mullender M, El Haj AJ, Yang Y, van Duin MA, Burger EH, Klein-Nulend J. Mechanotransduction of bone cells in vitro: mechanobiology of bone tissue. Med Biol Eng Comput. January 2004;42(1):14-21.
2008	Schindeler A, McDonald MM, Bokko P, Little DG. Bone remodeling during fracture repair: the cellular picture. Semin Cell Dev Biol. October 2008;19(5):459-466.
2004	Pearson OM, Lieberman DE. The aging of Wolff's “law”: ontogeny and responses to mechanical loading in cortical bone. Yearb Phys Anthropol. 2004;47:63-99.
2007	Jiang J. The Role of Cellular Interactions in Osteochondral Graft Design and the Maintenance of a Stable Osteochondral Interface [PhD thesis]. Columbia University; 2007.
2003	Bailón-Plaza A. Simulation of Fracture Healing Mediated by Growth Factors and Mechanical Stimulus [PhD thesis]. Ithaca, NY: Cornell University; May 2003.
2015	Allen AB. Modulation of Stem Cell Delivery Strategy by Platelet Lysate Utilization and Cell Aggregation for Enhanced Bone Regeneration [PhD thesis]. Atlanta, GA: Georgia Institute of Technology; August 2015.
2015	Priddy LB. Biomaterial Strategies for Improved Bone Healing With Bone Morphogenetic Protein-2 Delivery [PhD thesis]. Atlanta, GA: Georgia Institute of Technology; August 2015.
2007	Geris L. Mathematical Modelling of Bone Regeneration During Fracture Healing and Implant Osseointegration [PhD thesis]. Katholieke Universiteit Leuven; May 2007.
2000	Richman CC. In Vitro and in Vivo Studies on Bone Formation [PhD thesis]. Loma Linda University; March 2000.
2010	Gurkan UA. Engineering of Bone Marrow in Vitro for Investigating the Role of Growth Factors and Their Mechanoresponsiveness in Osteogenesis [PhD thesis]. Purdue University; May 2010.
2018	Yang F. The Synergistic Effect of Bone Graft Substitute Architecture and Mechanical Environment on HMSCs Responses in Vitro [PhD thesis]. Queen Mary University of London; December 2018.
2007	Tang SY-C. Effects of Non-Enzymatic Glycation on the Biomechanical Behavior of Bone [PhD thesis]. Troy, NY: Rensselaer Polytechnic Institute; 2007.
2004	De Ranieri A. Morphologic, Mechanical, and Molecular Aspects of TGF-Β2 Enhanced Implant Fixation [PhD thesis]. Rush University; 2004.
2012	Brennan MA. Close to the Bone: Investigations Into Bone Tissue Mineralisation and Mechanobiology of Osteoporosis [PhD thesis]. University of Southampton; January 2012.
2016	Yu Q. Applications of Human Bone Materials and Synthesized Biomaterials for Bone-Related Tissue Engineering [PhD thesis]. University of Akron; December 2016.
2010	Melhus G. Molecular Studies on Bone With Focus on Fracture Healing in Experimental Osteoporosis [PhD thesis]. Oslo, Norway: University of Oslo; 2010.
2015	Patel JJ. Single and Dual Growth Factor Delivery from Poly-Ε-Caprolactone Scaffolds for Pre-Fabricated Bone Flap Engineering [PhD thesis]. University of Michigan; 2015.