Organization of hydroxyapatite crystals within collagen fibrils

Weiner, Stephen; Traub, Wolfie

Affiliations

¹Isotope Department, The Weizmann Institute of Science, 76100 Rehovot, Israel

²Structural Chemistry Department, The Weizmann Institute of Science, 76100 Rehovot, Israel

Abstract and keywords

Transmission electron micrographs of individual mineralized collagen fibrils show that hydroxyapatite crystals are located mainly within the fibrils at the level of the gap regions. The plate-shaped crystals are observed to be more or less uniformly stacked across the fibril diameter. We therefore suggest that the crystals are primarily located in ‘grooves’ created by contiguous adjacent gaps. Thi proposal is consistent with the observed crystal distribution in the fibril and with their average widths, which are almost lo-times greater than an individual gap diameter.

Keywords: Collagen; Hydroxyapatite crystal; Biomineralization; (Bone, Turkey tendon)

Links

DOI: 10.1016/0014-5793(86)80993-0

PubMed: 3019771

WoS: A1986E461700017

History

Received: 1986-08-04

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Cited By (48)

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2009	Rath AL. The Effects of Strain and Perilacunar Environment on the Mechanotransduction of Osteocytes [PhD thesis]. Winston-Salem, NC: Wake Forest University; May 2009.