Collagen‐crystal relationships in bone as seen in the electron microscope

Robinson, R. A.<sup>1</sup>; Watson, M. L.<sup>1</sup>

Affiliations

¹Department of Surgery (Orthopaedics), The University of Rochester School of Medicine and Dentistry, Rochester, New York

²Department of Radiation Biology, The University of Rochester School of Medicine and Dentistry, Rochester, New York

Links

DOI: 10.1002/ar.1091140302

PubMed: 12996880

WoS: A1952UZ75400001

Cited Works (1)

Year	Entry
1952	Robinson RA. An electron-microscopic study of the crystalline inorganic component of bone and its relationship to the organic matrix. J Bone Joint Surg. April 1952;34A(2):389-435, 476.

Cited By (37)

Year	Entry
2021	Ahn T, Gidley DW, Thornton AW, Wong-Foy AG, Orr BG, Kozloff KM, Banaszak Holl MM. Hierarchical nature of nanoscale porosity in bone revealed by positron annihilation lifetime spectroscopy. ACS Nano. March 23, 2021;15(3):4321-4334.
2014	Reznikov N, Shahar R, Weiner S. Bone hierarchical structure in three dimensions. Acta Biomater. September 2014;10(8):3815-3826.
1998	Weiner S, Wagner HD. The material bone: structure-mechanical function relations. Ann Rev Mater Sci. August 1998;28:271-298.
2020	Reznikov N, Hoac B, Buss DJ, Addison WN, Barros NMT, McKee MD. Biological stenciling of mineralization in the skeleton: local enzymatic removal of inhibitors in the extracellular matrix. Bone. September 2020;138:115447.
1981	Chatterji S, Wall JC, Jeffery JW. Age-related changes in the orientation and particle size of the mineral phase in human femoral cortical bone. Calcif Tiss Int. December 1981;33(6):567-574.
1986	Weiner S, Price PA. Disaggregation of bone into crystals. Calcif Tiss Int. November 1986;39(6):365-375.
1988	Arsenault AL. Crystal-collagen relationships in calcified turkey leg tendons visualized by selected-area dark field electron microscopy. Calcif Tiss Int. October 1988;43(4):202-212.
1978	Jackson SA, Cartwright AG, Lewis D. The morphology of bone mineral crystals. Calcif Tiss Res. August 1978;25(3):217-222.
1960	Robinson RA. Crystal–collagen–water relationships in bone matrix. Clin Orthop Relat Res. 1960;17:69-76.
2020	Maghsoudi-Ganjeh M, Wang X, Zeng X. Nanomechanics and ultrastructure of bone: a review. Comput Model Eng Sci. 2020;125(1):1-32.
1994	Ziv V, Weiner S. Bone crystal sizes: a comparison of transmission electron microscopic and x-ray diffraction line width broadening techniques. Connect Tissue Res. 1994;30(3):165-175.
1992	Weiner S, Traub W. Bone structure: from ȧngstroms to microns. FASEB J. February 1992;6(3):879-885.
1986	Weiner S, Traub W. Organization of hydroxyapatite crystals within collagen fibrils. FEBS Lett. October 1986;206(2):262-266.
1991	Weiner S, Arad T, Traub W. Crystal organization in rat bone lamellae. FEBS Lett. July 1991;285(1):49-54.
1966	Cooper RR, Milgram JW, Robinson RA. Morphology of the osteon: an electron microscopic study. J Bone Joint Surg. October 1966;48A(7):1239-1271.
1970	Cooper RR, Misol S. Tendon and ligament insertion: a light and electron microscopic study. J Bone Joint Surg. January 1970;52A(1):1-20, 170.
1960	Smith JW. The arrangement of collagen fibres in human secondary osteones. J Bone Joint Surg. August 1960;42B(3):588-605.
1991	Lee DD, Glimcher MJ. Three-dimensional spatial relationship between the collagen fibrils and the inorganic calcium phosphate crystals of pickerel (Americanus americanus) and herring (Clupea harengus) bone. J Mol Biol. 1991;217(3):487-501.
1993	Landis WJ, Song MJ, Leith A, McEwen L, McEwen BF. Mineral and organic matrix interaction in normally calcifying tendon visualized in three dimensions by high-voltage electron microscopic tomography and graphic image reconstruction. J Struct Biol. January 1993;110(1):39-54.
2020	Raguin E, Rechav K, Brumfeld V, Shahar R, Weiner S. Unique three-dimensional structure of a fish pharyngeal jaw subjected to unusually high mechanical loads. J Struct Biol. August 1, 2020;211(2):107530.
1965	Ascenzi A, Bonucci E, Bocciarelli DS. An electron microscope study of osteon calcification. J Ultrastruct Res. April 1965;12(3-4):287-303.
1977	Landis WJ, Paine MC, Glimcher MJ. Electron microscopic observations of bone tissue prepared anhydrously in organic solvents. J Ultrastruct Res. April 1977;59(1):1-30.
2007	Olszta MJ, Cheng X, Jee SS, Kumar R, Kim Y-Y, Kaufman MJ, Douglas EP, Gower LB. Bone structure and formation: a new perspective. Mater Sci Eng R Rep. November 28, 2007;58(3-5):77-116.
2005	Nyman JS, Reyes M, Wang X. Effect of ultrastructural changes on the toughness of bone. Micron. October–December 2005;36(7-8):566-582.
1996	Landis WJ, Hodgens KJ, Arena J, Song MJ, McEwen BF. Structural relations between collagen and mineral in bone as determined by high voltage electron microscopic tomography. Microsc Res Tech. 1996;33(2):192-202.
1977	White SW, Hulmes DJS, Miller A, Timmins PA. Collagen-mineral axial relationship in calcified turkey leg tendon by X-ray and neutron diffraction. Nature. March 31, 1977;266(5601):421-425.
2012	McNally EA, Schwarcz HP, Botton GA, Arsenault AL. A model for the ultrastructure of bone based on electron microscopy of ion-milled sections. PLoS One. January 17, 2012;7(1):e29258.
1989	Traub W, Arad T, Weiner S. Three-dimensional ordered distribution of crystals in turkey tendon collagen fibers. Proc Natl Acad Sci USA. December 1989;86(24):9822-9826.
1959	Glimcher MJ. Molecular biology of mineralized tissues with particular reference to bone. Rev Mod Phys. April 1959;31(2):359-.
2005	Ho EY. Engineering Bioactive Polymers for the Next Generation of Bone Repair [PhD thesis]. Drexel University; April 2005.
2022	Gupta SD. Mineralized Tissues At the Osteochondral Junction in Healthy and Osteoarthritic Joints: Advanced Microimaging and Mechanical Studies [PhD thesis]. University of Oulu; 2022.
2011	Raghavan M. Investigation of Mineral and Collagen Organization in Bone Using Raman Spectroscopy [PhD thesis]. University of Michigan; 2011.
2020	Ahn T. Understanding Nanoscale Hierarchical Nature of Pore and Chemical Heterogeneity in Bone as a Function of Tissue Ages [PhD thesis]. University of Michigan; 2020.
2018	Burke MV. Quantification of Changes in Vertebral Bone Quality in the Presence of Metastases [PhD thesis]. University of Toronto; 2018.
2010	Reyes MJ. Age-Related Influence of Bone Remodeling on Local Tissue Properties of Human Cortical Bone [PhD thesis]. San Antionio, TX: University of Texas at San Antonio; December 2010.
2014	Reznikov N. The Adaptation of Mechanical Properties of Lamellar Bone Tissue [PhD thesis]. Weizmann Institute of Science; July 2014.
2012	Liu Y. The Mechanics of Bimaterial Attachment At the Tendon-to-Bone Insertion Site [PhD thesis]. St. Louis, MO: Washington University in St. Louis; May 2012.