Misconceptions (2):​ turnover is always higher in cancellous than in cortical bone

Parfitt, A. M.<sup>1</sup>

Affiliations

¹Division of Endocrinology and Center for Osteoporosis and Metabolic Bone Disease, University of Arkansas for Medical Sciences, Little Rock, AR, USA

Links

DOI: 10.1016/S8756-3282(02)00735-4

PubMed: 12052445

WoS: 000176469200001

History

Received: 2001-11-30

Revised: 2002-02-08

Accepted: 2002-02-12

Online: 2002-05-02

Cited Works (8)

Year	Entry
1992	Balena R, Shih M-S, Parfitt AM. Bone resorption and formation on the periosteal envelope of the ilium: a histomorphometric study in healthy women. J Bone Miner Res. December 1992;7(12):1475-1482.
1994	Parfitt AM. Osteonal and hemi‐osteonal remodeling: the spatial and temporal framework for signal traffic in adult human bone. J Cell Biochem. July 1994;55(3):273-286.
1992	Riggs BL, Melton LJ III. The prevention and treatment of osteoporosis. NEJM. August 27, 1992;327(9):620-627.
1996	Han Z, Palnitkar S, Rao DS, Nelson D, Parfitt AM. Effect of ethnicity and age or menopause on the structure and geometry of iliac bone. J Bone Miner Res. December 1996;11(12):1967-1975.
1997	Han Z-H, Palnitkar S, Rao DS, Nelson D, Parfitt AM. Effects of ethnicity and age or menopause on the remodeling and turnover of iliac bone: implications for mechanisms of bone loss. J Bone Miner Res. April 1997;12(4):498-508.
1984	Keshawarz NM, Recker RR. Expansion of the medullary cavity at the expense of cortex in postmenopausal osteoporosis. Metab Bone Dis Rel Res. 1984;5(5):223-228.
1983	Parfitt AM. The physiologic and clinical significance of bone histomorphometric data. In: Recker RR, ed. Bone Histomorphometry: Techniques and Interpretation. Boca Raton, FL: Inc., CRC Press; 1983:143-223.
1969	Frost HM. Tetracycline-based histological analysis of bone remodeling. Calcif Tiss Res. 1969;3(1):211-237.

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2020	Mulder B, Stock JT, Saers JPP, Inskip SA, Cessford C, Robb JE. Intrapopulation variation in lower limb trabecular architecture. Am J Phys Anthropol. September 2020;173(1):112-129.
2007	McDonnell P, McHugh PE, O’Mahoney D. Vertebral osteoporosis and trabecular bone quality. Ann Biomed Eng. February 2007;35(2):170-189.
2010	Easley SK, Jekir MG, Burghardt AJ, Li M, Keaveny TM. Contribution of the intra-specimen variations in tissue mineralization to pth- and raloxifene-induced changes in stiffness of rat vertebrae. Bone. April 2010;46(4):1162-1169.
2015	Reznikov N, Chase H, Brumfeld V, Shahar R, Weiner S. The 3D structure of the collagen fibril network in human trabecular bone: relation to trabecular organization. Bone. February 2015;71:189-195.
2022	Borggaard XG, Roux J-P, Delaisse J-M, Chavassieux P, Andreasen CM, Andersen TL. Alendronate prolongs the reversal-resorption phase in human cortical bone remodeling. Bone. July 2022;160:116419.
2022	Chen J-R, Lazarenko OP, Blackburn ML. GPR109A gene deletion ameliorates gonadectomy-induced bone loss in mice. Bone. August 2022;161:116422.
2023	Wong AKO, Fung HJW, Chan ACH, Szabo E, Mathur S, Giangregorio L, Cheung AM. Ankle flexor torque, size and density are differential determinants of distal tibia trabecular plate-rod morphometry and bone strength: the ankle quality study. Bone. January 2023;166:116582.
2023	Walle M, Whittier DE, Schenk D, Atkins PR, Blauth M, Zysset P, Lippuner K, Müller R, Collins CJ. Precision of bone mechanoregulation assessment in humans using longitudinal high-resolution peripheral quantitative computed tomography in vivo. Bone. July 2023;172:116780.
2023	Hendriks FK, Weijzen MEG, Goessens JPB, Zorenc AHG, Gijsen AP, Kramer IF, van den Bergh JPW, Poeze M, Blokhuis TJ, van Loon LJC. Trabecular, but not cortical, bone tissue protein synthesis rates are lower in the femoral head when compared to the proximal femur following an intracapsular hip fracture. Bone. December 2023;177:116921.
2020	Lerebours C, Weinkamer R, Roschger A, Buenzli PR. Mineral density differences between femoral cortical bone and trabecular bone are not explained by turnover rate alone. Bone Rep. December 1, 2020;13:100731.
2012	Slyfield CR, Tkachenko EV, Wilson DL, Hernandez CJ. Three-dimensional dynamic bone histomorphometry. J Bone Miner Res. February 2012;27(2):486-495.
2022	Ott SM. Consider the bisphosphonate dose. J Bone Miner Res. 2022;37(1):1-2.
2023	Lai C, Heinemann J, Schleicher U, Schett G, Bogdan C, Bozec A, Soulat D. Chronic systemic infection of mice with Leishmania infantum leads to increased bone mass. J Bone Miner Res. January 2023;38(1):86-102.
2018	Morton JJ, Bennison M, Lievers WB, Waldman SD, Pilkey AK. Failure behaviour of rat vertebrae determined through simultaneous compression testing and micro-CT imaging. J Mech Behav Biomed Mater. March 2018;79:73-82.
2011	Karim L, Vashishth D. Role of trabecular microarchitecture in the formation, accumulation, and morphology of microdamage in human cancellous bone. J Orthop Res. November 2011;29(11):1739-1744.
2007	Fratzl P, Weinkamer R. Nature’s hierarchical materials. Prog Mater Sci. November 2007;52(8):1263-1334.
2017	Saers JPP. Ontogeny and Functional Adaptation of Trabecular Bone in the Human Foot [PhD thesis]. Cambridge, UK: University of Cambridge; July 2017.
2012	Slyfield CR Jr. The Biomechanics of Bone Turnover [PhD thesis]. Ithaca, NY: Cornell University; January 2012.
2017	Matheny JB. Interactions Between Bone Remodeling and Microdamage in Cancellous Bone [PhD thesis]. Ithaca, NY: Cornell University; August 2017.
2005	Stauber M. Volumetric Spatial Decomposition of Porous Microstructures: A Framework for Element Based Analysis of Trabecular Bone [PhD thesis]. Swiss Federal Institute of Technology Zürich; 2005.
2019	Watson S. LIFTMOR: Lifting Intervention for Training Muscle and Osteoporosis Rehabilitation [PhD thesis]. Brisbane, Australia: Griffith University; January 2019.
2015	Newman CL. Assessing and Modifying Bone Quality in Chronic Kidney Disease [PhD thesis]. Indianapolis, IN: Indiana University; May 2015.
2019	Karadaş Ö. Biochemical and Mechanical Cues for Osteogenic Induction of Stem Cells on Paper Based Scaffolds [PhD thesis]. Izmir Institute of Technology; December 2019.
2021	Scott MC. Exercise and Bone: Older Adults, Type II Diabetes, and Ketogenic Diets [PhD thesis]. Louisiana State University; May 2021.
2017	Keune JA. The Role of Bone Marrow Adipose Tissue in Bone Loss During Spaceflight and Simulated Spaceflight in Rodents [PhD thesis]. Oregon State University; 2017.
2019	Jammy GR. Skeletal and Muscle Health Among Rural South Indian Older Population [PhD thesis]. University of Pittsburgh; 2019.
2013	Morton JJ. An Investigation of Rat Vertebra Failure Behaviour Under Uniaxial Compression Through Time-Lapsed Micro-CT Imaging [Master's thesis]. Queen's University; 2013.
2013	Toal VR. The Mechanics of Microdamage and Microfracture in Trabecular Bone [PhD thesis]. Brisbane, Australia: Queensland University of Technology; September 2013.
2011	Karim L. The Biomolecular Basis of Bone Fracture [PhD thesis]. Troy, NY: Rensselaer Polytechnic Institute; November 2011.
2016	Bailey SM. The Role of Extra-Cellular Matrix Proteins and Post-Translational Modifications on Bone Fracture [PhD thesis]. Troy, NY: Rensselaer Polytechnic Institute; September 2016.
2012	Acerbo AS. Local Chemical and Nanostructural Properties of Rat Cortical Bone Are Altered by Osteoporosis and Pharmaceutical Treatments [PhD thesis]. Stony Brook, NY: Stony Brook University; August 2012.
2008	Kennedy OD. The Effect of Bone Turnover on Bone Quality and Material Properties [PhD thesis]. Trinity College Dublin; 2008.
2005	Cooper DML. 3D Micro-CT Imaging of Human Cortical Bone Porosity: A Novel Method for Estimating Age At Death [PhD thesis]. Calgary, AB: University of Calgary; December 2005.
2019	Shtil M. Longitudinal Assessment of Mechanical Strength of Trabecular Bone Underlying Bone Marrow Lesions Following Acute Anterior Cruciate Ligament Injuries [Master's thesis]. Calgary, AB: University of Calgary; June 2019.
2022	Blank MA. Defining Mechanisms by Which EphrinB2 in Osteocytes Controls Bone Strength and Material Quality [PhD thesis]. University of Melbourne; September 2022.
2022	Nandi S. HRAS GTPase, a Novel Regulator of Bone Homeostasis: Understanding the Cellular Base of Bone Loss in Costello Syndrome [PhD thesis]. University of Ulm; 2022.
2021	Harrison KD. A Novel in Vivo Synchrotron Radiation Micro-CT Imaging Platform for the Direct Tracking of Remodeling Events in Cortical Bone [PhD thesis]. University of Saskatchewan; December 2021.
2016	Andronowski JM. Evaluating Differential Nuclear DNA Yield Rates Among Human Bone Tissue Types: A Synchrotron Micro-CT Approach [PhD thesis]. Knoxville, University of Tennessee; May 2016.
2014	Reznikov N. The Adaptation of Mechanical Properties of Lamellar Bone Tissue [PhD thesis]. Weizmann Institute of Science; July 2014.