Brain injury from the macro to the micro level and back again:​ what have we learned to date?

Thibault, Lawrence E.<sup>1</sup>

Affiliations

¹Department of Bioengineering, University of Pennsylvania

Cited Works (27)

Year	Entry
1989	Gennarelli TA, Thibault LE, Tipperman R, Tomei G, Sergot R, Brown M, Maxwell WL, Graham DI, Adams JH, Irvine A, Gennarelli LM, Duhaime AC, Boock R, Greenberg J. Axonal injury in the optic nerve: a model simulating diffuse axonal injury in the brain. J Neurosurg. August 1989;71(2):244-253.
1966	Ommaya AK, Hirsch AE, Flamm ES, Mahone RH. Cerebral concussion in the monkey: an experimental model. Science. July 8, 1966;153(3732):211-212.
1974	Ommaya AK, Gennarelli TA. Cerebral concussion and traumatic unconsciousness: correlation of experimental and clinical observations of blunt head injuries. Brain. December 1974;97(4):633-654.
1943	Holbourn AHS. Mechanics of head injuries. Lancet. October 9, 1943;242(6267):438-441.
1982	Gennarelli TA, Thibault LE, Adams JH, Graham DI, Thompson CJ, Marcincin RP. Diffuse axonal injury and traumatic coma in the primate. Ann Neurol. 1982;12(6):564-574.
1989	Winston FK. The Modulation of Intracellular Free-Calcium Concentration by Biaxial Extensional Strains of Bovine Pulmonary Artery Endothelial Cells [PhD thesis]. Philadelphia, PA: University of Pennsylvania; 1989.
1945	Holbourn AHS. The mechanics of brain injuries. Br Med Bull. January 1945;3(6):147-149.
1962	Gurdjian ES, Lissner HR, Patrick LM. Protection of the head and neck in sports. JAMA. November 3, 1962;182(5):509-512.
1966	Ommaya AK, Hirsch AE, Martinez JL. The role of whiplash in cerebral concussion. In: Proceedings of the 10th Stapp Car Crash Conference. November 8-9, 1966; Hollomon Air Force Base, NM. Warrendale, PA: Society of Automotive Engineers:314-324. SAE 660804.
1973	Bycroft GN. Mathematical model of a head subjected to an angular acceleration. J Biomech. 1973;6(5):487-495.
1989	Tong; DiMasi; Carr; Eppinger; Marcus, Galbraith C. Finite element modeling of head injury caused by inertial loading. In: Proceedings of the 12th International Technical Conference on Experimental Safety Vehicles (ESV). May 29–June 1, 1989; Göteborg, Sweden.617-627.
1990	Thibault LE, Gennarelli TA, Margulies SS, Marcus J, Eppinger R. The strain dependent pathophysiological consequences of inertial loading on central nervous system tissue. In: Proceedings of the 1990 International IRCOBI Conference on the Biomechanics of Impact. September 12-14, 1990; Lyon, France.191-202.
1991	Meaney DF. Biomechanics of Acute Subdural Hematoma in the Subhuman Primate and Man [PhD thesis]. Philadelphia, PA: University of Pennsylvania; 1991.
1978	Abel JM, Gennarelli TA, Segawa H. Incidence and severity of cerebral concussion in the rhesus monkey following sagittal plane angular acceleration. In: Proceedings of the 22nd Stapp Car Crash Conference. October 24-26, 1978; Ann Arobor, MI. Warrendale, PA: Society of Automotive Engineers:35-53. SAE 780886.
1989	Margulies SS, Thibault LE. An analytical model of traumatic diffuse brain injury. J Biomech Eng. August 1989;111(3):241-249.
1982	Gennarelli TA, Thibault LE. Biomechanics of acute subdural hematoma. J Trauma. 1982;22(8):680-686.
1987	Margulies SS. Biomechanics of Traumatic Coma in the Primate [PhD thesis]. Philadelphia, PA: University of Pennsylvania; 1987.
1988	Galbraith JA. The Effects of Mechanical Loading on the Electrophysiology of the Squid Giant Axon [PhD thesis]. Philadelphia, PA: University of Pennsylvania; 1988.
1972	Gennarelli TA, Thibault LE, Ommaya AK. Pathophysiologic responses to rotational and translational accelerations of the head. In: Proceedings of the 16th Stapp Car Crash Conference. November 8-10, 1972; Detroit, MI. Warrendale, PA: Society of Automotive Engineers:296-308. SAE 720970.
1974	Shatsky SA, Alter WA III, Evans DE, Armbrustmacher VW, Clark G. Traumatic distortions of the primate head and chest: correlation of biomechanical, radiological and pathological data. In: Proceedings of the 18th Stapp Car Crash Conference. December 4-5, 1974; Ann Arbor, MI. Warrendale, PA: Society of Automotive Engineers:351-381. SAE 741186.
1988	Hunter CM. Effects of Mechanical Loading on Ion Transport Through Lipid Bilayer Membranes [PhD thesis]. Philadelphia, PA: University of Pennsylvania; 1988.
1941	Denny-Brown D, Russell WR. Experimental cerebral concussion. Brain. September 1941;64(2-3):93-164.
1975	Ward CC, Thompson RB. The development of a detailed finite element brain model. In: Proceedings of the 19th Stapp Car Crash Conference. November 17-19, 1975; San Diego, CA. Warrendale, PA: Society of Automotive Engineers:641-674. SAE 751163.
1975	Ljung C. A model for brain deformation due to rotation of the skull. J Biomech. 1975;8(5):263-274.
1982	Khalil TB, Viano DC. Critical issues in finite element modeling of head impact. In: Proceedings of the 26th Stapp Car Crash Conference. October 20-21, 1982; Ann Arbor, MI. Warrendale, PA: Society of Automotive Engineers:87-102. SAE 821150.
1987	Lee M-C, Melvin JW, Ueno K. Finite element analysis of traumatic subdural hematoma. In: Proceedings of the 31st Stapp Car Crash Conference. November 9-11, 1987; New Orleans, LA. Warrendale, PA: Society of Automotive Engineers:67-77. SAE 872201.
1991	Barbee KA. Cellular Response of Vascular Smooth Muscle to Mechanical Stimuli [PhD thesis]. Philadelphia, PA: University of Pennsylvania; 1991.

Cited By (10)

Year	Entry
2002	Ommaya AK, Goldsmith W, Thibault L. Biomechanics and neuropathology of adult and paediatric head injury. Br J Radiol. June 2002;16(3):220-242.
2007	Mordaka J, Kleiven S, van Schijndel-de Nooij M, de Lange R, Guerra Casanova LJ, Carter EL, von Holst H. The importance of rotational kinematics in pedestrian head to windshield impacts. In: Proceedings of the 2007 International IRCOBI Conference on the Biomechanics of Impact. September 19-21, 2007; Maastricht, The Netherlands.83-94.
2007	Kleiven S. Predictors for traumatic brain injuries evaluated through accident reconstructions. Stapp Car Crash J. 2007;51:81-114. SAE 2007-22-0003.
2007	Tamura A, Nagayama K, Matsumoto T, Hayashi S. Variation in nerve fiber strain in brain tissue subjected to uniaxial stretch. Stapp Car Crash J. 2007;51:139-154. SAE 2007-22-0006.
2008	Takhounts EG, Ridella SA, Hasija V, Tannous RE, Campbell JQ, Malone D, Danelson K, Stitzel J, Rowson S, Duma S. Investigation of traumatic brain injuries using the next generation of Simulated Injury Monitor (SIMon) finite element head model. Stapp Car Crash J. 2008;52:1-31. SAE 2008-22-0001.
2010	Rousseau P, Hoshizaki TB, Gilchrist MD, Post A. Estimating the influence of neckform compliance on brain tissue strain during a helmeted impact. Stapp Car Crash J. 2010;54:37-48. SAE 2010-22-0003.
2004	Goldsmith W, Plunket J. A biomechanical analysis of the causes of traumatic brain injury in infants and children. Am J Forensic Med Pathol. June 2004;25(2):89-100.
2000	Smith DH, Meaney DF. Axonal damage in traumatic brain injury. Neuroscientist. December 2000;6(6):483-495.
2016	Kendall M. Comparison and Characterization of Different Concussive Brain Injury Events [PhD thesis]. University of Ottawa; 2016.
2018	Adanty K. A Comparison Between Two Oblique Test Protocols for Cycling Helmets [Master's thesis]. University of Ottawa; 2018.