Biomechanical response of the bovine pia-arachnoid complex to normal traction loading at varying strain rates

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Jin, Xin¹; Ma, Chunsheng^1,2; Zhang, Liying¹; Yang, King H.¹; King, Albert I.¹; Dong, Guang²; Zhang, Jinhuan²

Biomechanical response of the bovine pia-arachnoid complex to normal traction loading at varying strain rates

Stapp Car Crash J. 2007;51:115-126

Affiliations

¹Bioengineering Center, Wayne State University

²State Key Laboratory of Automotive Safety and Energy, Tsinghua University, P.R. China
Abstract and keywords

The pia-arachnoid complex (PAC) covering the brain plays an important role in the mechanical response of the brain due to impact or inertial loading. The mechanical properties of the bovine PAC under tensile loading have been characterized previously. However, the transverse properties of this structure, such as shear and normal traction which are equally important to understanding the skull/brain interaction under traumatic loading, have not been investigated. These material properties are essential information needed to adequately define the material model of the PAC in a finite element (FE) model of human brain.

The purpose of this study was to determine, experimentally, the material properties of the PAC under normal traction loading. PAC specimens were obtained from freshly slaughtered bovine subjects from various locations. Quasi-static and dynamic tests along the radial direction were performed at four different strain rates (0.36, 2.0, 20.5, and 116.3 s^-1) to investigate the rate and regional effects. Results suggest that the PAC under traction loading is stiffer than brain tissue, rate dependent, and can be characterized as linearly elastic until failure. However, no regional difference was observed.

Keywords: pia-arachnoid complex; normal traction properties; strain rate; dynamic loading; material properties
Links

PubMed: 18278593

SAE: 2007-22-0004

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Cited By (5)

Year	Entry
2016	Giordano C, Kleiven S. Development of a 3‐year‐old child FE head model, continuously scalable from 1.5‐ to 6‐ year‐old. In: Proceedings of the 2016 International IRCOBI Conference on the Biomechanics of Injury. September 14-16, 2016; Malaga, Spain.288-302.
2013	Mao H, Zhang L, Jiang B, Genthikatti VV, Jin X, Zhu F, Makwana R, Gill A, Jandir G, Singh A, Yang KH. Development of a finite element human head model partially validated with thirty five experimental cases. J Biomech Eng. November 2013;135(11):111002.
2016	Pasquesi SA. Can Vigorous Shaking Cause Extra-Axial Hemorrhage in Newborns? A Detailed Human and Porcine Study [PhD thesis]. Philadelphia, PA: University of Pennsylvania; 2016.
2014	Scott GG. Anatomy and Biomechanics of the Pia-Arachnoid Complex [Master's thesis]. University of Utah; August 2014.
2020	Zhou R. Development of Rat Head Finite Element Model and Tissue Level Biomechanical Threshold for Traumatic Axonal Injury [PhD thesis]. Detroit, MI: Wayne State University; May 2020.