Failure properties of passive human aortic tissue, I:​ uniaxial tension tests

Mohan, Dinesh<sup>1</sup>; Melvin, John W.<sup>2</sup>

Affiliations

¹Centre for Biomedical Engineering, Indian Institute of Technology, New Delhi 110016, India

²Biomechanics Department, Highway Safety Research Institute, The University of Michigan. Ann Arbor, Michigan 48109

Abstract

Samples of descending mid-thoracic aortas were obtained from human autopsies and experiments were performed to determine the effect of strain rate and direction of loading on the failure properties of the tissue in uniaxial tension. The tests were performed at quasi-static strain rates in the range 0.01 s⁻¹–0.07s⁻¹ and dynamic tests in the range 80s⁻¹–100s⁻¹. Ultimate stress and extension ratio values have been calculated for specimens tested in the longitudinal and transverse directions of the aorta.

Links

DOI: 10.1016/0021-9290(82)90055-0

PubMed: 7161291

WoS: A1982PY44000010

History

Received: 1982-06-22

Cited Works (6)

Year	Entry
1970	Yamada H. Strength of Biological Materials. Evans FG, ed. Baltimore, MD: Williams & Wilkins Company; 1970.
1959	Cammack K, Rapport RL, Paul J, Baird WC. Deceleration injuries of the thoracic aorta. Arch Surg. September 1959;79(2):244-251.
1976	Mohan D. Passive Mechanical Properties of Human Aortic Tissue [PhD thesis]. University of Michigan; 1976.
1972	Fung Y-CB. Stress-strain-history relations of soft tissues in simple elongation. In: Fung YC, Perrone N, Anliker M, eds. Biomechanics: Its Foundations and Objectives. Symposium on Biomechanics, its Foundations and Objectives; July 29-31, 1970. Englewood Cliff, NJ: Inc., Prentice-Hall International; 1972:181-208.
1966	Roberts VL, Jackson FR, Berkas EM. Heart motion due to blunt trauma to the thorax. In: Proceedings of the 10th Stapp Car Crash Conference. November 8-9, 1966; Hollomon Air Force Base, NM. Warrendale, PA: Society of Automotive Engineers:242-248. SAE 660800.
1966	Greendyke RM. Traumatic rupture of aorta: special reference to automobile accidents. JAMA. February 14, 1966;195(7):527-530.

Cited By (28)

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2005	Lee S-H, Darvish K, Lobovsky L. Modeling of the material properties and fluid-structure interaction in the traumatic rupture of aorta. In: Proceedings of the 19th International Technical Conference on the Enhanced Safety of Vehicles (ESV). June 6-9, 2005; Washington, DC.
2011	Digges K, Augenstein J, Hardy W, Cavanaugh J, Jermakian JS, Echemendia C, Shah C. Measurement of aortic injuries in lower severity near-side impacts. In: Proceedings of the 22nd International Technical Conference on the Enhanced Safety of Vehicles (ESV). June 13-16, 2011; Washington, DC.
2002	Mohan D. Traffic safety and thirty years of biomechanics research: a personal adventure. In: Proceedings of the 2002 International IRCOBI Conference on the Biomechanics of Impact. September 18-20, 2002; Munich, Germany.
2005	Stemper BD, Stineman MR, Yoganandan N, Pintar FA, Sinson GP, Gennarelli TA. Mechanical characterization of internal layer failure in the human carotid artery. In: Proceedings of the 2005 International IRCOBI Conference on the Biomechanics of Impact. September 21-23, 2005; Prague, Czech Republic.269-277.
2011	Belwadi A, Yang KH. Mechanism of aortic injury in nearside left lateral automotive crashes: a finite element accident injury reconstruction approach. In: Proceedings of the 2011 International IRCOBI Conference on the Biomechanics of Injury. September 14-16, 2011; Krakow, Poland.169-180.
2012	Litlzer S, Vezin P. Characterization of the intima layer of the aorta by digital image correlation in dynamic traction up to failure. In: Proceedings of the 2012 International IRCOBI Conference on the Biomechanics of Injury. September 12-14, 2012; Dublin, Ireland.650-661.
2014	Rastgar-Agah M, Assari S, Rachev A, Darvish K. High rate failure properties of aortic tissue. In: Proceedings of the 10th Ohio State University Injury Biomechanics Symposium. May 18-20, 2014; Columbus, OH.
1983	Viano DC. Biomechanics of nonpenetrating aortic trauma: a review. In: Proceedings of the 27th Stapp Car Crash Conference. October 17-19, 1983; San Diego, CA. Warrendale, PA: Society of Automotive Engineers:109-114. SAE 831608.
2002	Zhang L, Bae J, Hardy WN, Monson KL, Manley GT, Goldsmith W, Yang KH, King AI. Computational study of the contribution of the vasculature on the dynamic response of the brain. Stapp Car Crash J. 2002;46:145-164. SAE 2002-22-0008.
2007	Lee S-H, Kent R. Blood flow and fluid-structure interactions in the human aorta during traumatic rupture conditions. Stapp Car Crash J. 2007;51:211-233. SAE 2007-22-0010.
2008	Hardy WN, Shah CS, Mason MJ, Kopacz JM, Yang KH, King AI, Van Ee CA, Bishop JL, Banglmaier RF, Bey MJ, Morgan RM, Digges KH. Mechanisms of traumatic rupture of the aorta and associated peri-isthmic motion and deformation. Stapp Car Crash J. 2008;52:233-265. SAE 2008-22-0010.
1983	Mohan D, Melvin JW. Failure properties of passive human aortic tissue, II: biaxial tension tests. J Biomech. 1983;16(1):31-44.
1989	Viano DC, King AI, Melvin JW, Weber K. Injury biomechanics research: an essential element in the prevention of trauma. J Biomech. 1989;22(5):403-417.
1989	Lee M-C, Haut RC. Insensitivity of tensile failure properties of human bridging veins to strain rate: implications in biomechanics of subdural hematoma. J Biomech. 1989;22(6-7):537-542.
1983	Haut RC. Age-dependent influence of strain rate on the tensile failure of rat-tail tendon. J Biomech Eng. August 1983;105(3):296-299.
2003	Monson KL, Goldsmith W, Barbaro NM, Manley GT. Axial mechanical properties of fresh human cerebral blood vessels. J Biomech Eng. April 2003;125(2):288-294.
2009	Darvish K, Shafieian M, Romanov V, Rotella V, Salvatore MD Jr, Blebea J. Development of an in vitro porcine aorta model to study the stability of stent grafts in motor vehicle accidents. J Biomech Eng. April 2009;131(4):044505.
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