Clinical use of quantitative computed tomography–based finite element analysis of the hip and spine in the management of osteoporosis in adults:​ the 2015 ISCD official positions—part II

Zysset, Philippe<sup>1</sup>; Qin, Ling<sup>2</sup>; Lang, Thomas<sup>3</sup>; Khosla, Sundeep<sup>4</sup>; Leslie, William D.<sup>5,6</sup>; Shepherd, John A.<sup>4</sup>; Schousboe, John T.<sup>7,8</sup>; Engelke, Klaus<sup>9,10</sup>

Affiliations

¹Institute for Surgical Technology and Biomechanics, University of Bern, Bern, Switzerland

²Bone Quality and Health Center, Department of Orthopedics and Traumatology, The Chinese University of Hong Kong, Hong Kong, China

³Center for Clinical and Translational Science, Mayo Clinic College of Medicine, Rochester, MN, USA

⁴Department of Radiology and Biomedical Imaging, UCSF School of Medicine, San Francisco, CA, USA

⁵Department of Medicine, University of Manitoba, Winnipeg, Canada

⁶Department of Radiology, University of Manitoba, Winnipeg, Canada

⁷Park Nicollet Clinic/HealthPartners, Minneapolis, MN, USA

⁸Division of Health Policy and Management, University of Minnesota, Minneapolis, MN, USA

⁹Institute of Medical Physics, University of Erlangen, Erlangen, Germany

¹⁰Bioclinica, Hamburg, Germany

Abstract and keywords

The International Society for Clinical Densitometry (ISCD) has developed new official positions for the clinical use of quantitative computed tomography (QCT)-based finite element analysis of the spine and hip. The ISCD task force for QCT reviewed the evidence for clinical applications and presented a report with recommendations at the 2015 ISCD Position Development Conference. Here we discuss the agreed upon ISCD official positions with supporting medical evidence, rationale, controversy, and suggestions for further study. Parts I and III address the clinical use of QCT of the hip, and the clinical feasibility of existing techniques for opportunistic screening of osteoporosis using CT scans obtained for other diagnosis such as colonography was addressed.

Keywords: osteoporosis; position; quantitative computed tomography (QCT); finite element analysis (FEA)

Links

DOI: 10.1016/j.jocd.2015.06.011

PubMed: 26277852

WoS: 000359886000007

History

Received: 2015-06-25

Revised: 2015-06-25

Accepted: 2015-06-25

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2020	Sadoughi S, vom Scheidt A, Nawathe S, Zhu S, Moini A, Keaveny TM. Effect of variations in tissue-level ductility on human vertebral strength. Bone. August 2020;137:115445.
2021	Grassi L, Fleps I, Sahlstedt H, Väänänen SP, Ferguson SJ, Isaksson H, Helgason B. Validation of 3D finite element models from simulated DXA images for biofidelic simulations of sideways fall impact to the hip. Bone. January 2021;142:115678.
2021	Almendros-Abellán VM, Castro-García M, Canales-Vázquez J, Berenguel-Herraiz P, Sabater S. Alterations in femoral neck strength following pelvic irradiation: a finite element analysis of simulated eccentric forces using bone density data derived from CT. Bone. April 2021;145:115865.
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