Clinician’s guide to prevention and treatment of osteoporosis

Cosman, F.; de Beur, S. J.; LeBoff, M. S.; Lewiecki, E. M.; Tanner, B.; Randall, S.; Lindsay, R.

Year	Entry
2016	Kanis JA, Harvey NC, Cooper C, Johansson H, Odén A, McCloskey EV; The Advisory Board of the National Osteoporosis Guideline Group. A systematic review of intervention thresholds based on FRAX: a report prepared for the National Osteoporosis Guideline Group and the International Osteoporosis Foundation. Arch Osteoporos. December 2016;11(1):25.
2017	Curtis EM, Moon RJ, Harvey NC, Cooper C. The impact of fragility fracture and approaches to osteoporosis risk assessment worldwide. Bone. November 2017;104:29-38.
2020	Liphardt A-M, Windahl SH, Sehic E, Hannemann N, Gustafsson KL, Bozec A, Schett G, Engdahl C. Changes in mechanical loading affect arthritis-induced bone loss in mice. Bone. February 2020;131:115149.
2020	Schini M, Vilaca T, Poku E, Harnan S, Sutton A, Allen IE, Cummings SR, Eastell R. The risk of hip and non-vertebral fractures in patients with Parkinson's disease and parkinsonism: a systematic review and meta-analysis. Bone. March 2020;132:115173.
2020	Söreskog E, Ström O, Spångéus A, Åkesson KE, Borgström F, Banefelt J, Toth E, Libanati C, Charokopou M. Risk of major osteoporotic fracture after first, second and third fracture in Swedish women aged 50 years and older. Bone. May 2020;134:115286.
2020	Adami G, Arioli G, Bianchi G, Brandi ML, Caffarelli C, Cianferotti L, Gatti D, Girasole G, Gonnelli S, Manfredini M, Muratore M, Quarta E, Quarta L. Radiofrequency echographic multi spectrometry for the prediction of incident fragility fractures: a 5-year follow-up study. Bone. May 2020;134:115297.
2020	He Y, Li M, Tong G, Meng Y, Hao S, Hu S, Yan W, Yang D. hPTH(3-34)(29-34) selectively activated PKC and mimicked osteoanabolic effects of hPTH(1-34). Bone. June 2020;135:115326.
2020	Iki M, Yura A, Fujita Y, Kouda K, Tachiki T, Tamaki J, Sato Y, Moon J-S, Hamada M, Kajita E, Okamoto N, Kurumatani N. Relationships between serum uric acid concentrations, uric acid lowering medications, and vertebral fracture in community-dwelling elderly japanese men: Fujiwara-kyo Osteoporosis Risk in Men (FORMEN) Cohort Study. Bone. October 2020;139:115519.
2021	Savikangas T, Sipilä S, Rantalainen T. Associations of physical activity intensities, impact intensities and osteogenic index with proximal femur bone traits among sedentary older adults. Bone. February 2021;143:115704.
2021	Tang L, An S, Zhang Z, Fan X, Guo J, Sun L, Ta D. MSTN is a key mediator for low-intensity pulsed ultrasound preventing bone loss in hindlimb-suspended rats. Bone. February 2021;143:115610.
2021	Fuggle NR, Curtis B, Clynes M, Zhang J, Ward K, Javaid MK, Harvey NC, Dennison E, Cooper C. The treatment gap: the missed opportunities for osteoporosis therapy. Bone. March 2021;144:115833.
2023	Devries MC, Giangregorio L. Using the specificity and overload principles to prevent sarcopenia, falls and fractures with exercise. Bone. January 2023;166:116573.
2023	Cruchelow KR, Peter ME, Chakrabarti A, Gipson HM, Gregory WT, DeClercq J, Choi L, Tanner SB. Denosumab treatment lapses, discontinuation, and off-treatment fracture risk: a retrospective study of patients with osteoporosis in a real-world clinical setting. Bone. December 2023;177:116925.
2020	Rendina D, D’Elia L, Evangelista M, Filippo GD, Giaquinto A, Barone B, Piccinocchi G, Prezioso D, Strazzullo P. Osteoporosis is a predictive factor for nephrolithiasis in an adult free-living caucasian population from southern italy: a longitudinal retrospective study based on a general practice database. Calcif Tiss Int. November 2020;107(5):446-452.
2021	Xiao X, Wu Q. The utility of genetic risk score to improve performance of FRAX for fracture prediction in US postmenopausal women. Calcif Tiss Int. June 2021;108(6):746-756.
2017	Humbert L, Martelli Y, Fonollà R, Steghöfer M, Di Gregorio S, Malouf J, Romera J, del Río Barquero LM. 3D-DXA: assessing the femoral shape, the trabecular macrostructure and the cortex in 3D from DXA images. IEEE Trans Med Imaging. January 2017;36(1):27-39.
2016	Miller PD, Hattersley G, Riis BJ, Williams GC, Lau E, Russo LA, Alexandersen P, Zerbini CAF, Hu M-y, Harris AG, Fitzpatrick LA, Cosman F, Christiansen C; ACTIVE Study Investigators. Effect of abaloparatide vs placebo on new vertebral fractures in postmenopausal women with osteoporosis: a randomized clinical trial. JAMA. August 16, 2016;316(7):722-733.
2020	Mattazio RR, Noritomi PY, Silveira ZC. An in silico model for the prediction of changes in mineral density in cortical bone remodeling. J Biomech Eng. January 2020;142(1):011008.
2017	Khosla S, Cauley JA, Compston J, Kiel DP, Rosen C, Saag KG, Shane E. Addressing the crisis in the treatment of osteoporosis: a path forward. J Bone Miner Res. March 2017;32(3):424-430.
2019	Chang P, Feldman D, Stefanick ML, McDonnell DP, Thompson BM, McDonald JG, Lee JS. 27‐hydroxycholesterol, an endogenous SERM, and risk of fracture in postmenopausal women: a nested case‐cohort study in the Women's Health Initiative. J Bone Miner Res. January 2019;34(1):59-66.
2020	Conley RB, Adib G, Adler RA, Åkesson KE, Alexander IM, Amenta KC, Blank RD, Brox WT, Carmody EE, Chapman‐Novakofski K, Clarke BL, Cody KM, Cooper C, Crandall CJ, Dirschl DR, Eagen TJ, Elderkin AL, Fujita M, Greenspan SL, Halbout P, Hochberg MC, Javaid M, Jeray KJ, Kearns AE, King T, Koinis TF, Koontz JS, Kužma M, Lindsey C, Lorentzon M, Lyritis GP, Michaud LB, Miciano A, Morin SN, Mujahid N, Napoli N, Olenginski TP, Puzas JE, Rizou S, Rosen CJ, Saag K, Thompson E, Tosi LL, Tracer H, Khosla S, Kiel DP. Secondary fracture prevention: consensus clinical recommendations from a multistakeholder coalition. J Bone Miner Res. January 2020;35(1):36-52.
2020	LeBoff MS, Chou SH, Murata EM, Donlon CM, Cook NR, Mora S, Lee I, Kotler G, Bubes V, Buring JE, Manson JE. Effects of supplemental vitamin D on bone health outcomes in women and men in the VITamin D and OmegA‐3 TriaL (VITAL). J Bone Miner Res. May 2020;35(5):883-893.
2020	Li G, Leslie WD, Kovacs CS, Prior J, Josse RG, Towheed T, Davison KS, Thabane L, Papaioannou A, Levine MAH, Goltzman D, Zeng J, Qi Y, Tian J, Adachi JD; Canadian Multicentre Osteoporosis Study (CaMos) Research Group. Combining frailty and trabecular bone score did not improve predictive accuracy in risk of major osteoporotic fractures. J Bone Miner Res. June 2020;35(6):1058-1064.
2020	Wang Q, Chen D, Jin H, Ye Z, Wang C, Chen K, Kuek V, Xu K, Qiu H, Chen P, Song D, Zhao J, Liu Q, Davis RA, Song F, Xu J. Hymenialdisine: a marine natural product that acts on both osteoblasts and osteoclasts and prevents estrogen‐dependent bone loss in mice. J Bone Miner Res. August 2020;35(8):1582-1596.
2020	Bon J, Nouraie SM, Smith KJ, Dransfield MT, McDonald M, Hoffman EA, Newell JD Jr, Comellas AP, Saha PK, Bowler RP, Regan EA. Lung‐specific risk factors associated with incident hip fracture in current and former smokers. J Bone Miner Res. October 2020;35(10):1952-1961.
2021	Talevski J, Sanders KM, Busija L, Beauchamp A, Duque G, Borgström F, Kanis JA, Svedbom A, Connaughton C, Stuart AL, Brennan‐Olsen SL. Health service use and quality of life recovery 12 months following major osteoporotic fracture: latent class analyses of the international costs and utilities related to osteoporotic fractures study (icuros). J Bone Miner Res. February 2021;36(2):252-261.
2022	Pérez-Castrillón JL, Dueñas-Laita A, Gómez-Alonso C, Bouillon R, Jódar E, Brandi ML, González-Macías J, Quesada-Gómez JM, Martínez JMO, Galarraga B, Pino-Montes Jd, Expósito MRA, Castro FC, López LG, Hernández-Herrero G, Fernández-Hernando N, Arranz-Gutiérrez P, Chinchilla SP. Reply to calcifediol is not superior to cholecalciferol in improving vitamin D status in postmenopausal women. J Bone Miner Res. 2022;37(7):1413-1415.
2022	Buettmann EG, Goldscheitter GM, Hoppock GA, Friedman MA, Suva LJ, Donahue HJ. Similarities between disuse and age-induced bone loss. J Bone Miner Res. August 2022;37(8):1417-1434.
2022	Lu T, Forgetta V, Greenwood CMT, Richards JB. Identifying causes of fracture beyond bone mineral density: evidence from human genetics. J Bone Miner Res. August 2022;37(8):1592-1602.
2022	Farzi M, Pozo JM, McCloskey E, Eastell R, Harvey NC, Frangi AF, Wilkinson JM. Quantitating age-related BMD textural variation from DXA region-free-analysis: a study of hip fracture prediction in three cohorts. J Bone Miner Res. September 2022;37(9):1679-1688.
2022	Pineda-Moncusí M, El-Hussein L, Delmestri A, Cooper C, Moayyeri A, Libanati C, Toth E, Prieto-Alhambra D, Khalid S. Estimating the incidence and key risk factors of cardiovascular disease in patients at high risk of imminent fracture using routinely collected real-world data from the UK. J Bone Miner Res. October 2022;37(10):1986-1996.
2022	Leslie WD, Morin SN, Lix LM, McCloskey EV, Johansson H, Harvey NC, Kanis JA. Effect of discordant hip bone density on incident fracture risk: a registry-based cohort study. J Bone Miner Res. October 2022;37(10):2018-2024.
2022	Czerwinski E, Cardona J, Plebanski R, Recknor C, Vokes T, Saag KG, Binkley N, Lewiecki EM, Adachi J, Knychas D, Kendler D, Orwoll E, Chen Y, Pearman L, Li YH, Mitlak B. The efficacy and safety of abaloparatide-sc in men with osteoporosis: a randomized clinical trial. J Bone Miner Res. December 2022;37(12):2435-2442.
2023	Cosman F, Hans D, Shevroja E, Wang Y, Mitlak B. Effect of abaloparatide on bone microarchitecture assessed by trabecular bone score in women with osteoporosis: post hoc analysis of ACTIVE and ACTIVExtend. J Bone Miner Res. April 2023;38(4):464-470.
2023	Pérez-Castrillón JL, Dueñas-Laita A, Gómez-Alonso C, Jódar E, Pino-Montes Jd, Brandi ML, Castro FC, Quesada-Gómez JM, López LG, Martínez JMO, Expósito MRA, Galarraga B, González-Macías J, Neyro JL, Bouillon R, Hernández-Herrero G, Fernández-Hernando N, Chinchilla SP. Long-term treatment and effect of discontinuation of calcifediol in postmenopausal women with vitamin D deficiency: a randomized trial. J Bone Miner Res. April 2023;38(4):471-479.
2023	Kirk B, Harrison SL, Zanker J, Burghardt AJ, Orwoll E, Duque G, Cawthon PM. Interactions between HR-pQCT bone density and D₃Cr muscle mass (or HR-pQCT bone structure and HR-pQCT muscle density) in predicting fractures: the osteoporotic fractures in men study. J Bone Miner Res. September 2023;38(9):1245-1257.
2023	Fink HA, Butler ME, Claussen AM, Collins ES, Krohn KM, Taylor BC, Tikabo SS, Vang D, Zerzan NL, Ensrud KE. Performance of fracture risk assessment tools by race and ethnicity: a systematic review for the ASBMR task force on clinical algorithms for fracture risk. J Bone Miner Res. December 2023;38(12):1731-1741.
2023	Alarkawi D, Tran T, Chen W, March LM, Blyth FM, Blank RD, Bliuc D, Center JR. Denosumab and mortality in a real-world setting: a comparative study. J Bone Miner Res. December 2023;38(12):1757-1770.
2015	Zysset P, Qin L, Lang T, Khosla S, Leslie WD, Shepherd JA, Schousboe JT, Engelke K. Clinical use of quantitative computed tomography–based finite element analysis of the hip and spine in the management of osteoporosis in adults: the 2015 ISCD official positions—part II. J Clin Densitom. July–September 2015;18(3):359-392.
2019	Eastell R, Rosen CJ, Black DM, Cheung AM, Murad MH, Shoback D. Pharmacological management of osteoporosis in postmenopausal women: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. May 2019;104(5):1595-1622.
2023	Haffer H, Chiapparelli E, Moser M, Muellner M, Dodo Y, Amini DA, Zhu J, Miller TT, Han YX, Donnelly E, Shue J, Sama AA, Cammisa FP, Girardi FP, Hughes AP. Dermal ultrasound measurements for bone quality assessment: an investigation of advanced glycation endproducts derived from confocal fluorescence microscopy. J Orthop Res. February 2023;41(2):345-354.
2018	Kendler DL, Marin F, Zerbini CAF, Russo LA, Greenspan SL, Zikan V, Bagur A, Malouf-Sierra J, Lakatos P, Fahrleitner-Pammer A, Lespessailles E, Minisola S, Body JJ, Geusens P, Möricke R, López-Romero P. Effects of teriparatide and risedronate on new fractures in post-menopausal women with severe osteoporosis (VERO): a multicentre, double-blind, double-dummy, randomised controlled trial. Lancet. January 20, 2018;391(10117):230-240.
2019	Compston JE, McClung MR, Leslie WD. Osteoporosis. Lancet. January 26, 2019;393(10169):364-376.
2016	Black DM, Rosen CJ. Postmenopausal osteoporosis. NEJM. January 21, 2016;374(3):254-262.
2018	Reid IR, Horne AM, Mihov B, Stewart A, Garratt E, Wong S, Wiessing KR, Bolland MJ, Bastin S, Gamble GD. Fracture prevention with zoledronate in older women with osteopenia. NEJM. December 20, 2018;379(25):2407-2416.
2017	Harvey NCW, McCloskey EV, Mitchell PJ, Dawson-Hughes B, Pierroz DD, Reginster J-Y, Rizzoli R, Cooper C, Kanis JA. Mind the (treatment) gap: a global perspective on current and future strategies for prevention of fragility fractures. Osteoporos Int. May 2017;28(5):1507-1529.
2018	Rubin KH, Rothmann MJ, Holmberg T, Høiberg M, Möller S, Barkmann R, Glüer CC, Hermann AP, Bech M, Gram J, Brixen K. Effectiveness of a two-step population-based osteoporosis screening program using FRAX: the randomized Risk-stratified Osteoporosis Strategy Evaluation (ROSE) study. Osteoporos Int. March 2018;29(3):567-578.
2019	Kanis JA, Cooper C, Rizzoli R, Reginster J-Y; Scientific Advisory Board of the European Society for Clinical and Economic Aspects of Osteoporosis (ESCEO); Committees of Scientific Advisors and National Societies of the International Osteoporosis Foundation (IOF). European guidance for the diagnosis and management of osteoporosis in postmenopausal women. Osteoporos Int. January 2019;30(1):3-44.
2019	Balasubramanian A, Zhang J, Chen L, Wenkert D, Daigle SG, Grauer A, Curtis JR. Risk of subsequent fracture after prior fracture among older women. Osteoporos Int. January 2019;30(1):79-92.
2020	Löffler MT, Sollmann N, Mei K, Valentinitsch A, Noël PB, Kirschke JS, Baum T. X-ray-based quantitative osteoporosis imaging at the spine. Osteoporos Int. February 2020;31(2):233-250.
2020	Sosa-Henríquez M. Cholecalciferol and calcifediol for vitamin D supplementation. Osteoporos Int. February 2020;31(2):391-392.
2020	Wang Y, Yu S, Hsu C, Tsai C, Cheng T. Underestimated fracture risk in postmenopausal women: application of the hybrid intervention threshold. Osteoporos Int. March 2020;31(3):475-483.
2020	Keaveny TM, Clarke BL, Cosman F, Orwoll ES, Siris ES, Khosla S, Bouxsein ML. Biomechanical computed tomography analysis (BCT) for clinical assessment of osteoporosis. Osteoporos Int. June 2020;31(6):1025-1048.
2020	Leslie WD, Schousboe JT, Morin SN, Martineau P, Lix LM, Johansson H, McCloskey EV, Harvey NC, Kanis JA. Fracture risk following high-trauma versus low-trauma fracture: a registry-based cohort study. Osteoporos Int. June 2020;31(6):1059-1067.
2020	Leslie WD, Schousboe JT, Morin SN, Martineau P, Lix LM, Johansson H, McCloskey EV, Harvey NC, Kanis JA. Measured height loss predicts incident clinical fractures independently from FRAX: a registry-based cohort study. Osteoporos Int. June 2020;31(6):1079-1087.
2020	Cui R, Sun SQ, Zhong N, Xu MX, Cai HD, Zhang G, Qu S, Sheng H. The relationship between atherosclerosis and bone mineral density in patients with type 2 diabetes depends on vascular calcifications and sex. Osteoporos Int. June 2020;31(6):1135-1143.
2020	Zhou J, Huo X, Xue Y. Comments on Min et al. effects of anti-osteoporosis medications on radiological and clinical results after acute osteoporotic spinal fractures: a retrospective analysis of prospectively designed study. Osteoporos Int. June 2020;31(6):1181-1181.
2020	Ruiz-Adame M, Correa M. A systematic review of the indirect and social costs studies in fragility fractures. Osteoporos Int. July 2020;31(7):1205-1216.
2020	Nayak S, Greenspan SL. Cost-effectiveness of five versus ten years of alendronate treatment prior to drug holiday for women with osteoporosis. Osteoporos Int. July 2020;31(7):1273-1282.
2020	Wang Y, Zhao R, Gu Z, Dong C, Guo G, Li L. Effects of glucocorticoids on osteoporosis in rheumatoid arthritis: a systematic review and meta-analysis. Osteoporos Int. August 2020;31(8):1401-1409.
2020	Aboudiab M, Grados F, Batteux B, Henry-Desailly I, Fardellone P, Goëb V. Vertebral fracture assessment (VFA) in patients over 50 years of age with a non-severe peripheral fracture. Osteoporos Int. August 2020;31(8):1477-1486.
2020	Kanis JA, Johansson H, Harvey NC, Gudnason V, Sigurdsson G, Siggeirsdottir K, Lorentzon M, Liu E, Vandenput L, McCloskey EV. Adjusting conventional FRAX estimates of fracture probability according to the recency of sentinel fractures. Osteoporos Int. October 2020;31(10):1817-1828.
2020	Jazinizadeh F, Adachi JD, Quenneville CE. Advanced 2D image processing technique to predict hip fracture risk in an older population based on single DXA scans. Osteoporos Int. October 2020;31(10):1925-1933.
2020	Kanis JA, Cooper C, Dawson-Hughes B, Harvey NC, Johansson H, Lorentzon M, McCloskey EV, Reginster J-Y, Rizzoli R; International Osteoporosis Foundation. FRAX and ethnicity. Osteoporos Int. November 2020;31(11):2063-2067.
2020	Lewiecki EM, Wright NC, Singer AJ. Racial disparities, FRAX, and the care of patients with osteoporosis. Osteoporos Int. November 2020;31(11):2069-2071.
2020	Lewiecki EM, Binkley N, Clark P, Kim S, Leslie WD, Morin SN. Core principles for fracture prevention: North American Consensus from the National Osteoporosis Foundation, Osteoporosis Canada, and Academia Nacional de Medicina de Mexico. Osteoporos Int. November 2020;31(11):2073-2076.
2020	Christensen DL, Nappo KE, Wolfe JA, Tropf JG, Berge MJ, Wheatley BM, Saxena S, Yow BG, Tintle SM. Ten-year fracture risk predicted by proximal femur Hounsfield units. Osteoporos Int. November 2020;31(11):2123-2130.
2020	McClung MR, Bolognese MA, Brown JP, Reginster J-Y, Langdahl BL, Maddox J, Shi Y, Rojeski M, Meisner PD, Grauer A. A single dose of zoledronate preserves bone mineral density for up to 2 years after a second course of romosozumab. Osteoporos Int. November 2020;31(11):2231-2241.
2020	Yang J, Cosman F, Stone PW, Li M, Nieves JW. Vertebral fracture assessment (VFA) for osteoporosis screening in US postmenopausal women: is it cost-effective? Osteoporos Int. December 2020;31(12):2321-2335.
2020	Choi M-K, Bae Y-J. Protein intake and osteosarcopenic adiposity in Korean adults aged 50 years and older. Osteoporos Int. December 2020;31(12):2363-2372.
2021	Ho-Le TP, Tran HTT, Center JR, Eisman JA, Nguyen HT, Nguyen TV. Assessing the clinical utility of genetic profiling in fracture risk prediction: a decision curve analysis. Osteoporos Int. February 2021;32(2):271-280.
2021	Lee Y-F, Tsou H-K, Leong P-Y, Wang Y-H, Wei JC-C. Association of sepsis with risk for osteoporosis: a population-based cohort study. Osteoporos Int. February 2021;32(2):301-309.
2021	Guo F, Song X, Li Y, Guan W, Pan W, Yu W, Li T, Hsieh E. Longitudinal change in bone mineral density among Chinese individuals with HIV after initiation of antiretroviral therapy. Osteoporos Int. February 2021;32(2):321-332.
2021	Leslie WD, Edwards B, Al-Azazi S, Yan L, Lix LM, Czaykowski P, Singh H. Cancer patients with fractures are rarely assessed or treated for osteoporosis: a population-based study. Osteoporos Int. February 2021;32(2):333-341.
2021	Lems WF, Paccou J, Zhang J, Fuggle NR, Chandran M, Harvey NC, Cooper C, Javaid K, Ferrari S, Akesson KE; International Osteoporosis Foundation Fracture Working Group. Vertebral fracture: epidemiology, impact and use of DXA vertebral fracture assessment in fracture liaison services. Osteoporos Int. March 2021;32(3):399-411.
2021	Sagalla N, Colón-Emeric C, Sloane R, Lyles K, Vognsen J, Lee R. FRAX without BMD can be used to risk-stratify veterans who recently sustained a low trauma non-vertebral/non-hip fracture. Osteoporos Int. March 2021;32(3):467-472.
2021	Fang Y, Zhu J, Fan J, Sun L, Cai S, Fan C, Zhong Y, Li Y. Dietary Inflammatory Index in relation to bone mineral density, osteoporosis risk and fracture risk: a systematic review and meta-analysis. Osteoporos Int. April 2021;32(4):633-643.
2021	Lane NE, Saag K, O’Neill TJ, Manion M, Shah R, Klause U, Eastell R. Real-world bone turnover marker use: impact on treatment decisions and fracture [published correction appears in Osteoporos Int. March 2021;32(3):609-609]. Osteoporos Int. May 2021;32(5):831-840.
2021	Min C, Yoo DM, Wee JH, Lee H-J, Choi HG. High-intensity physical activity with high serum vitamin D levels is associated with a low prevalence of osteopenia and osteoporosis: a population-based study. Osteoporos Int. May 2021;32(5):883-891.
2020	Li X, Xu Y, Lin W, Fan Y. The comparison of bone mineral density of femoral head between non-hip fracture side and hip fracture side. Sci Rep. 2020;10:13015.
2016	Pisani P, Renna MD, Conversano F, Casciaro E, Di Paola M, Quarta E, Muratore M, Casciaro S. Major osteoporotic fragility fractures: risk factor updates and societal impact. World J Orthop. March 18, 2016;7(3):171-181.
2017	Billington E. Emerging Issues in Osteoporosis [MD thesis]. Auckland, New Zealand: University of Auckland; 2017.
2020	Gardezi M. Comparative Efficacy of Six Different Metods of RNA Extraction from Human Trabecular Bone and Comparison of Mineralization to Collagen Levels in Osteoinduced Stem Cells [Master's thesis]. Boston University; 2020.
2017	Unal M. Classification of Bound Water and Collagen Denaturation Status of Cortical Bone by Raman Spectroscopy [PhD thesis]. Cleveland, OH: Case Western Reserve University; January 2017.
2021	Coulombe JC. Diminished Bone Structural Quality in Aging and Microgravity Follow Impairments of the Osteocyte Lacunar-Canalicular System [PhD thesis]. University of Colorado; 2021.
2012	Mulholland B. The Role of Post-Menopausal Osteoporosis in Bone Metastatic Breast Cancer and the Effect of Monocyte Chemoattractant Protein-1 [PhD thesis]. Brisbane, Australia: Griffith University; April 2012.
2017	Bakalova LP. Relating Cortical Bone Mechanics to Intracortical Pore Morphology, Distribution and Remodeling History Within the Fibula Diaphysis [Master's thesis]. University of Illinois at Urbana-Champaign; 2017.
2023	Tippen SP. Interactions Between Aging and Chronic Kidney Disease on the Skeleton [PhD thesis]. Indianapolis, IN: Indiana University; May 2023.
2018	Wang M. Effect of Osteonal Microstructure on Crack Propagation: A Computational Study [PhD thesis]. Loughborough University; October 2018.
2022	Lu T. Leveraging Complex Disease Polygenic Risk Scores for Improved Risk Prediction and Identification of Rare Genetic Conditions [PhD thesis]. McGill University; April 2022.
2020	Jazinizadeh F. Assessment of Hip Fracture Risk in Older Adults by Considering the Effect of Geometry and Bone Mineral Density Distribution in the Femur Using Single Dual-Energy X-Ray Absorptiometry Scans [PhD thesis]. Hamilton, ON: McMaster University; August 2020.
2021	Moon E. Aging Alters Cervical Vertebral Bone Density Distribution [Master's thesis]. The Ohio State University; 2021.
2019	Jammy GR. Skeletal and Muscle Health Among Rural South Indian Older Population [PhD thesis]. University of Pittsburgh; 2019.
2019	Beltejar M-JG. Understanding the Genetic Basis for Bone-Matrix Quality [PhD thesis]. University of Rochester; 2019.
2020	Doolittle ML. Dissecting the Genetic Influences on Osteoporosis Reveals Zbtb40* as a Novel Regulator of Osteoblast Function* [PhD thesis]. University of Rochester; 2020.
2016	Bailey SM. The Role of Extra-Cellular Matrix Proteins and Post-Translational Modifications on Bone Fracture [PhD thesis]. Troy, NY: Rensselaer Polytechnic Institute; September 2016.
2017	Owen R. Tissue Engineering an in Vitro Model of Osteoporosis [PhD thesis]. Sheffield, UK: University of Sheffield; October 2017.
2021	Frank M. Mechanical Characterization of Individual Trabeculae [PhD thesis]. Vienna University of Technology; February 2021.
2018	George JK. Using Finite Element Models Under Multiple Loading Conditions to Improve the Association Between Radius and Tibia Microarchitecture and Prevalent Osteoporotic Vertebral Fracture [Master's thesis]. Calgary, AB: University of Calgary; May 2018.
2021	Whittier DEW. The Assessment of Fragility Fracture Risk Using HR-PQCT as a Novel Tool for Diagnosis of Osteoporosis [PhD thesis]. Calgary, AB: University of Calgary; August 2021.
2019	Sadoughi S. Micromechanics of Human Bone: Role of Architecture and Tissue Material Properties [PhD thesis]. Berkeley, CA: Berkeley, University of California; 2019.
2019	Colón-Bernal ID. Unraveling Chemical Composition Heterogeneity of Type I Collagen in Trabecular Bone as a Function of Disease and Treatment [PhD thesis]. University of Michigan; 2019.
2019	Surowiec R. Novel Models to Image and Quantify Bone Drug Efficacy and Disease Progression in Vivo: Addressing the Fragility Phenotype [PhD thesis]. University of Michigan; 2019.
2022	Nandi S. HRAS GTPase, a Novel Regulator of Bone Homeostasis: Understanding the Cellular Base of Bone Loss in Costello Syndrome [PhD thesis]. University of Ulm; 2022.
2021	Harrison KD. A Novel in Vivo Synchrotron Radiation Micro-CT Imaging Platform for the Direct Tracking of Remodeling Events in Cortical Bone [PhD thesis]. University of Saskatchewan; December 2021.
2022	Ponzano M. Risk Assessment and Interventions for Individuals At Risk of Osteoporotic Fractures [PhD thesis]. University of Waterloo; 2022.
2020	Mancuso ME. Defining the Multiscale Relationship Between Subject-Specific Bone Strain and Structural Adaptation in the Distal Radius of Women [PhD thesis]. Worcester, MA: Worcester Polytechnic Institute; July 2020.

Year	Entry
2007	Khosla S, Burr D, Cauley J, Dempster DW, Ebeling PR, Felsenberg D, Gagel RF, Gilsanz V, Guise T, Koka S, McCauley LK, McGowan J, McKee MD, Mohla S, Pendrys DG, Raisz LG, Ruggiero SL, Shafer DM, Shum L, Silverman SL, Van Poznak CH, Watts N, Woo S-B, Shane E. Bisphosphonate-associated osteonecrosis of the jaw: report of a task force of the American Society for Bone and Mineral Research. J Bone Miner Res. October 2007;22(10):1479-1491.
1994	Kanis JA, Melton LJ III, Christiansen C, Johnston CC, Khaltaev N. The diagnosis of osteoporosis. J Bone Miner Res. August 1994;9(8):1137-1141.
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