The effect of impact on the marrow pressure of long bones in vitro

Bryant, J. D.

Affiliations

¹Department of Biology, University of York, U.K

Abstract

Intact fresh sheep tibiae were subjected to non-destructive impact loads while maintained in an environment like that encountered in life. Under a maximum load of 2.5 kN, and loading rate of 500N ms⁻¹, marrow pressures no higher than 50 k Pa were recorded. Such low pressures would provide only a trivial amount of hydraulic strengthening, and are consistent with results from other workers carried out at lower rates of loading.

Links

DOI: 10.1016/0021-9290(83)90117-3

PubMed: 6643538

WoS: A1983RN86400012

History

Received: 1982-10-27

Revised: 1983-01-1

Online: 2004-03-19

Cited Works (4)

Year	Entry
1977	Carter DR, Hayes WC. The compressive behavior of bone as a two-phase porous structure. J Bone Joint Surg. 1977;59A(7):954-962.
1966	Swanson SAV, Freeman MAR. Is bone hydraulically strengthened? Med Biol Eng. September 1966;4(5):433-438.
1976	Hayes WC, Carter DR. Postyield behavior of subchondral trabecular bone. J Biomed Mater Res. July 1976;10(4):537-544.
1981	Piekarski K. Mechanically enhanced perfusion of bone. In: Cowin SC, ed. Mechanical Properties of Bone. The Joint ASME-ASCE Applied Mechnics, Fluids Engineering and Bioengineering Conference; June 22-24, 1981; Boulder, CO. New York, NY: American Society of Mechical Engineers; 1981:185-191.

Cited By (20)

Year	Entry
2001	Cowin SC. Bone poroelasticity. In: Cowin SC, ed. Bone Mechanics Handbook. 2nd ed. Boca Raton, FL: CRC Press; 2001:23-1–23-31.
2002	Currey JD. Bones: Structure and Mechanics. Princeton, NJ: Princeton University Press; 2002.
2008	Gurkan UA, Akkus O. The mechanical environment of bone marrow: a review. Ann Biomed Eng. December 2008;36(12):1978-1991.
2004	Hellmich C, Ulm F-J, Dormieux L. Can the diverse elastic properties of trabecular and cortical bone be attributed to only a few tissue-independent phase properties and their interactions? arguments from a multiscale approach. Biomech Model Mechanobiol. June 2004;2(4):219-238.
2006	Xie L, Jacobson JM, Choi ES, Busa B, Donahue LR, Miller LM, Rubin CT, Judex S. Low-level mechanical vibrations can influence bone resorption and bone formation in the growing skeleton. Bone. November 2006;39(5):1059-1066.
1994	Courtney AC, Wachtel EF, Myers ER, Hayes WC. Effects of loading rate on strength of the proximal femur. Calcif Tiss Int. 1994;55(1):53-58.
1999	Cowin SC. Bone poroelasticity. J Biomech. March 1999;32(3):217-238.
2003	Qin Y-X, Kaplan T, Saldanha A, Rubin C. Fluid pressure gradients, arising from oscillations in intramedullary pressure, is correlated with the formation of bone and inhibition of intracortical porosity. J Biomech. October 2003;36(10):1427-1437.
2011	Brynk T, Hellmich C, Fritsch A, Zysset P, Eberhardsteiner J. Experimental poromechanics of trabecular bone strength: role of Terzaghi's effective stress and of tissue level stress fluctuations. J Biomech. 2011;44(3):501-508.
2004	Samuel SP. Fluid/solid Interactions in Cancellous Bone [PhD thesis]. Cleveland State University; August 2004.
2013	Souzanchi MF. The Effect of Microarchitecture and Fabric Anisotropy of Trabecular Bone on Its Mechanical Behavior [PhD thesis]. New York, NY: The City University of New York; 2013.
1994	Courtney AC. Mechanical Properties of the Proximal Femur: Changes With Age [PhD thesis]. Cambridge, MA: Harvard University; May 1994.
2015	Gargac J. Evaluation of Bone Healing, Damage, and Adaptation Using Computational Modeling and Image Processing Techniques [PhD thesis]. University of Notre Dame; July 2015.
2016	Metzger TA. Experimental and Computational Investigation of Bone Marrow Mechanobiology [PhD thesis]. University of Notre Dame; April 2016.
2013	Verbruggen SW. Mechanobiological Origins of Osteoporosis [PhD thesis]. National University of Ireland Galway; September 2013.
2010	Gurkan UA. Engineering of Bone Marrow in Vitro for Investigating the Role of Growth Factors and Their Mechanoresponsiveness in Osteogenesis [PhD thesis]. Purdue University; May 2010.
2006	Xie L. Low Level Mechanical Vibrations Enhance Musculoskeletal Accretion in Growing Mice [PhD thesis]. Stony Brook, NY: Stony Brook University; December 2006.
2003	Ominsky MS. Effects of Hydrostatic Pressure, Biaxial Strain, and Fluid Shear on Osteoblastic Cells: Mechanotransduction Via NF-ΚB, MAP Kinase, and AP-1 Pathways [PhD thesis]. University of Michigan; 2003.
2010	Soves CP. The Potential Role of Megakaryocytes in Mechanically Mediated Bone Adaptation [PhD thesis]. University of Michigan; 2010.
2011	Rieger R. Modélisation mécano-biologique par éléments finis de l'os trabéculaire: Des activités cellulaires au remodelage osseux [Mechano-Biological Modeling of Trabecular Bone by Finite Elements: From Cells’ Activities to Bone Remodeling] [PhD thesis]. University of Orleans; 2011.