High-intensity physical activity with high serum vitamin D levels is associated with a low prevalence of osteopenia and osteoporosis:​ a population-based study

Min, C.; Yoo, D. M.; Wee, J. H.; Lee, H.-J.; Choi, H. G.

Affiliations

¹Hallym Data Science Laboratory, Hallym University College of Medicine, Anyang, Korea

²Graduate School of Public Health, Seoul National University, Seoul, Korea

³Department of Otorhinolaryngology-Head & Neck Surgery, Hallym University College of Medicine, Anyang, Korea

Abstract and keywords

Summary: We found that combination of high-intensity PA and high 25(OH)D levels was associated with low prevalence of osteoporosis/osteopenia. In addition, the prevalence of osteoporosis was lower in the low PA with high 25(OH)D levels than in the moderate or high PA with low 25(OH)D levels.

Introduction: The aim of this study was to explore the association of physical activity (PA) and serum 25-hydroxyvitamin D (25[OH]D) levels with osteopenia/osteoporosis.

Methods: The Korean National Health and Nutrition Examination Survey data from 2008 to 2011 were used in this study. Data from 6868 individuals were selected. Each individual’s level of PA was classified as ‘low’, ‘moderate’, or ‘high’. Serum 25(OH)D levels were classified as ‘low’ or ‘high’. Accordingly, the combined PA and 25(OH)D groups were divided into 6 groups. Bone mineral density (BMD) was classified as ‘normal (T score ≥ − 1.0)’, ‘osteopenia (− 2.5 < T score < − 1.0)’ or ‘osteoporosis (T score ≤ − 2.5)’. Crude and adjusted odds ratios (AORs) with 95% confidence intervals (CIs) were calculated using multinomial logistic regression models.

Results: The AORs (95% CIs) for osteopenia were 0.64 (0.50–0.83) in the high PA with high 25(OH)D group and 0.69 (0.53–0.88) in the moderate PA with high 25(OH)D group. The AORs (95% CIs) for osteoporosis were increased in the groups in ascending order as follows: high PA with high 25(OH)D (0.40 [0.28–0.57]) < moderate PA with high 25(OH)D (0.47 [0.33–0.66]) < low PA with high 25(OH)D (0.59 [0.42–0.83]) < high PA with low 25(OH)D (0.70 [0.49–1.00]) < moderate PA with low 25(OH)D (0.76 [0.53–1.07]) < low PA with low 25(OH)D. This result was consistent in males but not evident in females.

Conclusion: We suggest that the combination of high-intensity PA and high 25(OH)D levels is positively associated with high BMD.

Keywords: Bone mineral density; Osteopenia; Osteoporosis; Physical activity; Serum 25-hydroxyvitamin D; Vitamin D

Links

DOI: 10.1007/s00198-020-05746-w

PubMed: 33230576

WoS: 000591946800001

History

Received: 2020-05-02

Accepted: 2020-11-13

Online: 2020-11-23

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