Evaluation of macrostructural bone biomechanics

Beaupied, Hélène<sup>1</sup>; Lespessailles, Eric<sup>1</sup>; Benhamou, Claude-Laurent<sup>1</sup>

Affiliations

¹IPROS, Inserm U658, CHR Orléans, Hôpital Porte Madeleine, 1 rue Porte Madeleine – BP 2439, 45032 Orléans Cedex 1, France

Abstract and keywords

Bone fragility can be defined as an increased risk of fractures. Advanced age and bone diseases such as osteoporosis increase the fracture risk. Understanding the effects of osteoporosis and its treatments requires a description of the mechanical behavior of bone tissue. To this end, an entire bone can be studied, or the cortical and trabecular components can be investigated separately. We review the biomechanical tests available for measuring the ability of bone to withstand torsional, compressive, tensile, and bending forces.

Keywords: Bone; Bending; Compression; Traction; Torsion; Fatigue fracture

Links

DOI: 10.1016/j.jbspin.2007.01.019

PubMed: 17382570

WoS: 000247233800004

History

Received: 2006-06-19

Accepted: 2006-11-27

Online: 2007-02-23

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Year	Entry
2013	Shang-cheng W, Dong-mei W, Fang W, Qiu-gen W, Chun-hui W, Shan-guang C. Tensile and compressive mechanical property of human bone tissue [in Chinese]. Ch J Tissue Eng Res. 2013;17(7):1180-1184.
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2019	Asgari M, Abi-Rafeh J, Hendy GN, Pasini D. Material anisotropy and elasticity of cortical and trabecular bone in the adult mouse femur via AFM indentation. J Mech Behav Biomed Mater. May 2019;93:81-92.
2020	Hart NH, Newton RU, Tan2 J, Rantalainen T, Chivers P, Siafarikas A, Nimphius S. Biological basis of bone strength: anatomy, physiology and measurement. J Musculoskel Neuron Interact. September 2020;20(3):347-371.
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2017	Vaughan PE. The Impact of Developmental Age and Loading Rate on the Patterns of Bone Fracture Under Torsion and Bending Using Either Immature Porcine or Ovine Femurs [Master's thesis]. East Lansing, MI: Michigan State University; 2017.
2012	Acerbo AS. Local Chemical and Nanostructural Properties of Rat Cortical Bone Are Altered by Osteoporosis and Pharmaceutical Treatments [PhD thesis]. Stony Brook, NY: Stony Brook University; August 2012.
2012	Evdokimenko E. Investigation Into Mechanical Properties of Bone and Its Main Constituents [PhD thesis]. San Diego (UCSD), University of California; 2012.
2021	Romanowicz GE. The Role of Collagen Cross-Linking in Craniofacial and Long Bone Mineralization and Healing [PhD thesis]. University of Michigan; 2021.
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2016	Collins CJ. A Comprehensive Evaluation of Methods to Determine Mechanical Properties of Long Bone [PhD thesis]. University of Wisconsin – Madison; 2016.
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