MADYMO is a compact general purpose computer program package for two- or threedimensional Crash Victim Simulations. The program predicts the kinematic and dynamic behaviour of the victim during the crash, based on data of the victim, environment, safety devices and crash conditions. The package differs from most of the existing CVS programs by its flexibility in choice of number of linkages and number of elements in each linkage. Great flexibility in the modelling of force interactions between elements and environment is assured by the fact that user-defined submodels can readily be incorporated. The program is used in basic biomechanical crash research as well as the development and optimisation of crash safety devices such as seat belts and child seats. This paper briefly discusses the theoretical basis and the use of MADYMO, with some examples of applications.