A parametric study of age-related factors affecting intracranial responses under impact loading using a human head/brain FE model

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Yanaoka, Toshiyuki¹; Dokko, Yasuhiro¹

A parametric study of age-related factors affecting intracranial responses under impact loading using a human head/brain FE model

Proceedings of the 2013 International IRCOBI Conference on the Biomechanics of Injury

Affiliations

¹Honda R&D Co., Ltd. Automobile R&D center, Japan
Abstract and keywords

The high frequency of fatal head injuries in elderly people in traffic accidents is one of the important issues in Japan. One of the causes may be vulnerability of the aged brain. While a human head/brain FE model is a useful tool to investigate head injury mechanism, there has not been such a model considering the structural and qualitative changes of the brain caused by aging. The objective of this study was to clarify the influence of intracranial changes on intracranial responses relating to brain injuries, which could be the basic knowledge to develop a head/brain model capable of representing injury mechanisms of the aged brain. The influence of eight factors representing structural and material features on intracranial response was parametrically studied using a human head/brain FE model. Furthermore, influence of the impact direction was studied swapping the axis in the model along which the acceleration pulses were applied. The following results were found: 1) PAC (Pia-Arachnoid Complex) layer volume and stiffness of bridging vein (BV) had a strong influence on elongation of BV, 2) stiffness of the brain strongly influenced dilatational damage measure (DDM) and 3) stiffness of the brain and PAC layer volume had a strong influence on cumulative strain damage measure (CSDM).

Keywords: age-related changes, brain Injuries, human FE model, parametric study
Links

URL: http://www.ircobi.org/downloads/irc13/pdf_files/50.pdf

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2017	Guleyupoglu B, Barnard R, Gayzik FS. Failed rib regions in a computational human model vs. observed PMHS fractures: a comparative study. In: Proceedings of the 13th Ohio State University Injury Biomechanics Symposium. May 21-23, 2017; Columbus, OH.
2014	Vavalle NA, Schoell SL, Weaver AA, Stitzel JD, Gayzik FS. Application of radial basis function methods in the development of a 95th percentile male seated FEA model. Stapp Car Crash J. November 2014;58:361-384.
2015	Vavalle NA, Davis ML, Stitzel JD, Gayzik FS. Quantitative validation of a human body finite element model using rigid body impacts. Ann Biomed Eng. September 2015;43:2163-2174.
2019	Pak W. Development and Validation of Human Body Finite Element Models for Pedestrian Protection [PhD thesis]. Virginia Polytechnic Institute and State University; September 17, 2019.
2023	Grindle DM. Protection of Standing and Seated Pedestrians Using Finite Element Analysis [PhD thesis]. Virginia Polytechnic Institute and State University; April 27, 2023.
2015	Vavalle NA. The Application of a Radial Basis Function Morphing Technique to a Validated Full Human Body Finite Element Model [PhD thesis]. Winston-Salem, NC: Wake Forest University; May 2015.
2017	Davis ML. Development and Full Body Validation of a 5th Percentile Female Finite Element Model [PhD thesis]. Winston-Salem, NC: Wake Forest University; January 2017.