Concussion:​ mechanism and pathology

Gurdjian, E. S.<sup>1</sup>; Lissner, H. R.<sup>2</sup>; Patrick, L. M.<sup>2</sup>

Affiliations

¹Department of Neurosurgery, College of Medicine

²College of Engineering, Wayne State University

Abstract

There is currently much confusion regarding the meaning of the term "concussion." In an attempt to bring some order out of the chaos in which the subject finds itself, various aspects of the problem are critically examined. Our main source of knowledge of the concussive phenomena comes from animal experimentation and this fact imposes certain limitations which must be kept in mind when applying the results to human experience.

Cited Works (1)

Year	Entry
1944	Walker AE, Kollros JJ, Case TJ. The physiological basis of concussion. J Neurosurg. March 1944;1(2):103-116.

Cited By (35)

Year	Entry
1999	Eppinger R, Sun E, Bandak F, Haffner M, Khaewpong N, Maltese M, Kuppa S, Nguyen T, Takhounts E, Tannous R, Zhang A, Saul R. Development of Improved Injury Criteria for the Assessment of Advanced Automotive Restraint Systems - II. Washington, DC: National Highway Traffic Safety Administration (NHTSA); November 1999.
1998	Kleinberger M, Sun E, Eppinger R, Kuppa S, Saul R. Development of Improved Injury Criteria for the Assessment of Advanced Automotive Restraint Systems. Washington, DC: National Highway Traffic Safety Administration (NHTSA); September 1998.
2001	Zhang L, Yang KH, King AI. Biomechanics of neurotrauma. Neurol Res. March–April 2001;23(2-3):144-156.
1970	Patrick LM, Sato TB. Methods of establishing human tolerance levels: cadaver and animal research and clinical observations. In: Gurdjian ES, Lange WA, Patrick LM, Thomas LM, eds. Impact Injury and Crash Protection. Springfield, IL: Charles C. Thomas; 1970:259-273.
1970	Stapp JP. Voluntary human tolerance levels. In: Gurdjian ES, Lange WA, Patrick LM, Thomas LM, eds. Impact Injury and Crash Protection. Springfield, IL: Charles C. Thomas; 1970:308-349.
2005	Yoganandan N, Pintar FA, Zhang J, Gennarelli TA, Beuse N. Biomechanical aspects of blunt and penentrating head injuries. In: Gilchrist MD, ed. IUTAM Symposium on Impact Biomechanics: From Fundamental Insights to Applications. Dordrecht, The Netherlands: Springer; 2005:173-184. Solid Mechanics and Its Applications; vol 124.
1998	Lawson AR, Sadeghi MM. Finite element modelling of blunt or non-contact head injuries. In: Proceedings of the 16th International Technical Conference on the Enhanced Safety of Vehicles (ESV). May 31–June 4, 1998; Windsor, Ontario, Canada.2080-2092.
2003	Dokko Y, Anderson R, Manavis J, Blumburgs P, McLean J, Zhang L, Yang KH, King AI. Validation of the human head FE model against pedestrian accident and its tentative application to the examination of the existing tolerance curve. In: Proceedings of the 18th International Technical Conference on the Enhanced Safety of Vehicles (ESV). May 19-22, 2003; Nagoya, Japan.
2003	King AI, Yang KH, Zhang L, Hardy W, Viano DC. Is head injury caused by linear or angular acceleration? In: Proceedings of the 2003 International IRCOBI Conference on the Biomechanics of Impact. September 25, 2003; Lisbon, Portugal.1-12.
2005	Arbogast KB, Jermakian JS, Ghati Y, Smith R, Maltese MR, Menon RA. Predictors and patterns of pediatric head injury in motor vehicle crashes. In: Proceedings of the 2005 International IRCOBI Conference on the Biomechanics of Impact. September 21-23, 2005; Prague, Czech Republic.15-27.
2007	Deck C, Baumgartner D, Willinger R. Influence of rotational acceleration on intracranial mechanical parameters under accidental circumstances. In: Proceedings of the 2007 International IRCOBI Conference on the Biomechanics of Impact. September 19-21, 2007; Maastricht, The Netherlands.185-197.
2016	Oeur RA, Hoshizaki TB. The effect of impact compliance, velocity, and location in predicting brain trauma for falls in sport. In: Proceedings of the 2016 International IRCOBI Conference on the Biomechanics of Injury. September 14-16, 2016; Malaga, Spain.228-238.
1965	Patrick LM, Lissner HR, Gurdjian ES. Survival by design: head protection. In: Severy DM, ed. Proceedings of the 7th Stapp Car Crash and Field Demonstration Conference. 1963; University of California at Los Angeles. Springfield, IL: Charles C. Thomas; 1965:483-499.
1969	Hodgson VR, Thomas LM, Gurdjian ES, Fernando OU, Greenberg SW, Chason JL. Advances in understanding of experimental concussion mechanisms. In: Proceedings of the 13th Stapp Car Crash Conference. December 2-4, 1969; Boston, MA. Warrendale, PA: Society of Automotive Engineers:18-37. SAE 690796.
1970	Portnoy HD, Benjamin D, Brian M, McCoy LE, Pince B, Edgerton R, Young J. Intracranial pressure and head acceleration during whiplash. In: Proceedings of the 14th Stapp Car Crash Conference. November 17-18, 1970; Ann Arbor, MI. Warrendale, PA: Society of Automotive Engineers:152-168. SAE 700900.
1972	Hodgson VR, Mason MW, Thomas LM. Head model for impact. In: Proceedings of the 16th Stapp Car Crash Conference. November 8-10, 1972; Detroit, MI. Warrendale, PA: Society of Automotive Engineers:1-13. SAE 720969.
2001	Zhang L, Yang KH, Dwarampudi R, Omori K, Li T, Chang K, Hardy WN, Khalil TB, King AI. Recent advances in brain injury research: a new human head model development and validation. Stapp Car Crash J. 2001;45:369-394. SAE 2001-22-0017.
2005	Walilko TJ, Viano DC, Bir CA. Biomechanics of the head for Olympic boxer punches to the face. Br J Sports Med. October 2005;39(10):710-719.
2004	Zhang L, Yang KH, King AI. A proposed injury threshold for mild traumatic brain injury. J Biomech Eng. 2004;126(2):226-236.
2020	King AI, Grimm MJ. Herbert R. Lissner: the father of impact biomechanics. J Biomech Eng. March 2020;142(3):030801.
1971	Moon DW, Beedle CW, Kovacic CR. Peak head acceleration of athletes during competition: football. Med Sci Sports. Spring 1971;3(1):44-50.
2005	Viano DC, Casson IR, Pellman EJ, Zhang L, King AI, Yang KH. Concussion in professional football: brain responses by finite element analysis: part 9. Neurosurgery. November 2005;57(5):891-916.
2005	Viano DC, Casson IR, Pellman EJ, Bir CA, Zhang L, Sherman DC, Boitano MA. Concussion in professional football: comparison with boxing head impacts: part 10. Neurosurgery. December 2005;57(6):1154-1172.
2012	Post A, Hoshizaki TB. Mechanisms of brain impact injuries and their prediction: a review. Trauma. October 2012;14(4):327-349.
2016	Rush GA. Design of an American Football Helmet Liner for Concussion Mitigation [PhD thesis]. Mississippi State University; August 2016.
2014	Patton DA. The Biomechanical Determinants of Sports-Related Concussion: Finite Element Simulations of Unhelmeted Head Impacts to Evaluate Kinematic and Tissue-Level Predictors of Injury and Investigate the Design Implications for Soft-Shell Headgear [PhD thesis]. University of New South Wales; March 2014.
2013	Post A. The Influence of Dynamic Response Characteristics on Traumatic Brain Injury [PhD thesis]. Ottawa, ON: University of Ottawa; 2013.
2016	Kendall M. Comparison and Characterization of Different Concussive Brain Injury Events [PhD thesis]. University of Ottawa; 2016.
2018	Adanty K. A Comparison Between Two Oblique Test Protocols for Cycling Helmets [Master's thesis]. University of Ottawa; 2018.
2018	Oeur RA. The Effects of Reconstructed Head Impact Event Parameters on Risk of Sport Related Concussions [PhD thesis]. Ottawa, ON: University of Ottawa; 2018.
2019	Karton C. Profiling Brain Trauma in Professional American-Style Football and the Implications to Developing Neurological Injury [PhD thesis]. Ottawa, ON: University of Ottawa; 2019.
2022	Murphy A. Comparing Equestrian Helmets With and Without Rotational Technology Using an Equestrian Concussive Specific Helmet Test Protocol [Master's thesis]. University of Ottawa; 2022.
1968	Hodgson VR. Head Impact Response of Several Mammals Including the Human Cadaver [PhD thesis]. Detroit, MI: Wayne State University; 1968.
2001	Zhang L. Computational Biomechanics of Traumatic Brain Injury: An Investigation of Head Impact Response and American Football Head Injury [PhD thesis]. Detroit, MI: Wayne State University; May 2001.
2004	Walilko TJ. Biomechanical Response of the Temporomandibular Joint from Impacts in Boxing [PhD thesis]. Detroit, MI: Wayne State University; December 2004.