Role of collagen and other organics in the mechanical properties of bone

Currey, John D.

Year	Entry
2021	Ahn T, Gidley DW, Thornton AW, Wong-Foy AG, Orr BG, Kozloff KM, Banaszak Holl MM. Hierarchical nature of nanoscale porosity in bone revealed by positron annihilation lifetime spectroscopy. ACS Nano. March 23, 2021;15(3):4321-4334.
2018	Wu D, Isaksson P, Ferguson SJ, Persson C. Young’s modulus of trabecular bone at the tissue level: a review. Acta Biomater. September 15, 2018;78:1.
2014	Marinozzi F, Bini F, Quintino A, Corcione M, Marinozzi A. Experimental study of diffusion coefficients of water through the collagen: apatite porosity in human trabecular bone tissue. BioMed Res Int. 2014;2014:796519.
2005	Borah B, Ritman EL, Dufresne TE, Jorgensen SM, Liu S, Sacha J, Phipps RJ, Turner RT. The effect of risedronate on bone mineralization as measured by micro-computed tomography with synchrotron radiation: correlation to histomorphometric indices of turnover. Bone. July 2005;37(1):1-9.
2006	Garnero P, Borel O, Gineyts E, Duboeuf F, Solberg H, Bouxsein ML, Christiansen C, Delmas PD. Extracellular post-translational modifications of collagen are major determinants of biomechanical properties of fetal bovine cortical bone. Bone. March 2006;38(3):300-309.
2006	Viguet-Carrin S, Roux JP, Arlot ME, Merabet Z, Leeming DJ, Byrjalsen I, Delmas PD, Bouxsein ML. Contribution of the advanced glycation end product pentosidine and of maturation of type I collagen to compressive biomechanical properties of human lumbar vertebrae. Bone. November 2006;39(5):1073-1079.
2007	Yan J, Mecholsky JJ Jr, Clifton KB. How tough is bone? application of elastic–plastic fracture mechanics to bone. Bone. February 2007;40(2):479-484.
2007	Ruffoni D, Fratzl P, Roschger P, Klaushofer K, Weinkamer R. The bone mineralization density distribution as a fingerprint of the mineralization process. Bone. May 2007;40(5):1308-1319.
2009	Busse B, Hahn M, Soltau M, Zustin J, Püschel K, Duda GN, Amling M. Increased calcium content and inhomogeneity of mineralization render bone toughness in osteoporosis: mineralization, morphology and biomechanics of human single trabeculae. Bone. December 2009;45(6):1034-1043.
2020	Xi L, De Falco P, Barbieri E, Karunaratne A, Bentley L, Esapa CT, Davis GR, Terrill NJ, Cox RD, Pugno NM, Thakker RV, Weinkamer R, Wu WW, Fang DN, Gupta HS. Reduction of fibrillar strain-rate sensitivity in steroid-induced osteoporosis linked to changes in mineralized fibrillar nanostructure. Bone. February 2020;131:115111.
2022	Bonicelli A, Kranioti EF, Xhemali B, Arnold E, Zioupos P. Assessing bone maturity: compositional and mechanical properties of rib cortical bone at different ages. Bone. February 2022;155:116265.
2020	Fujita R, Ota M, Sato D, Nakazawa D, Kimura-Suda H, Nakamura F, Shimizu T, Kobayashi H, Iwasaki N, Takahata M. Comparison of the efficacy and renal safety of bisphosphonate between low-dose/high-frequency and high-dose/low-frequency regimens in a late-stage chronic kidney disease rat model. Calcif Tiss Int. October 2020;107(4):389-402.
2005	Felsenberg D, Boonen S. The bone quality framework: determinants of bone strength and their interrelationships, and implications for osteoporosis management. Clin Ther. January 2005;27(1):1-11.
2020	Maghsoudi-Ganjeh M, Wang X, Zeng X. Nanomechanics and ultrastructure of bone: a review. Comput Model Eng Sci. 2020;125(1):1-32.
2019	Semaan M, Karam E, Baron C, Pithioux M. Estimation of the elastic modulus of child cortical bone specimens via microindentation. Connect Tissue Res. July 4, 2019;60(4):399-405.
2016	Osterhoff G, Morgan EF, Shefelbine SJ, Karim L, McNamara LM, Augat P. Bone mechanical properties and changes with osteoporosis. Injury. June 2016;47(suppl 2):S11-S20.
2008	Yan J, Daga A, Kumar R, Mecholsky JJ. Fracture toughness and work of fracture of hydrated, dehydrated, and ashed bovine bone. J Biomech. 2008;41(9):1929-1936.
2011	Dall'Ara E, Öhman C, Baleani M, Viceconti M. Reduced tissue hardness of trabecular bone is associated with severe osteoarthritis. J Biomech. May 17, 2011;44(8):1593-1598.
2010	Donnelly E, Boskey AL, Baker SP, van der Meulen MCH. Effects of tissue age on bone tissue material compositionand nanomechanical properties in the rat cortex. J Biomed Mater Res. March 1, 2010;A92(3):1048-1056.
2015	McNerny EMB, Gong B, Morris MD, Kohn DH. Bone fracture toughness and strength correlate with collagen cross-link maturity in a dose-controlled lathyrism mouse model. J Bone Miner Res. March 2015;30(3):455-464.
2023	Lekkala S, Sacher SE, Taylor EA, Williams RM, Moseley KF, Donnelly E. Increased advanced glycation endproducts, stiffness, and hardness in iliac crest bone from postmenopausal women with type 2 diabetes mellitus on insulin. J Bone Miner Res. February 2023;38(2):261-277.
2005	Gupta HS, Schratter S, Tesch W, Roschger P, Berzlanovich A, Schoeberl T, Klaushofer K, Fratzl P. Two different correlations between nanoindentation modulus and mineral content in the bone–cartilage interface. J Struct Biol. February 2005;149(2):138-148.
2008	Utku FS, Klein E, Saybasili H, Yucesoy CA, Weiner S. Probing the role of water in lamellar bone by dehydration in the environmental scanning electron microscope. J Struct Biol. 2008;162(3):361-367.
2007	Fritsch A, Hellmich C. “Universal” microstructural patterns in bone: micromechanics-based prediction of anisotropic material behavior. J Theo Biol. February 21, 2007;244(4):597-620.
2006	Sambrook P, Cooper C. Osteoporosis. Lancet. June 17, 2006;367(9527):2010-2018.
2007	Olszta MJ, Cheng X, Jee SS, Kumar R, Kim Y-Y, Kaufman MJ, Douglas EP, Gower LB. Bone structure and formation: a new perspective. Mater Sci Eng R Rep. November 28, 2007;58(3-5):77-116.
2003	Bouxsein ML. Bone quality: where do we go from here? Osteoporos Int. September 2003;14(suppl 5):S118-S127.
2006	Viguet-Carrin S, Garnero P, Delmas PD. The role of collagen in bone strength. Osteoporos Int. March 2006;17(3):319-336.
2008	Ruppel ME, Miller LM, Burr DB. The effect of the microscopic and nanoscale structure on bone fragility. Osteoporos Int. September 2008;19(9):1251-1265.
2013	Cesar R, Boffa RS, Fachine LT, Leivas TP, Silva AMH, Pereira CAM, Reiff RBM, Rollo JMDA. Evaluation of trabecular microarchitecture of normal osteoporotic and osteopenic human vertebrae. Procedia Eng. 2013;59:6-15.
2017	Unal M. Classification of Bound Water and Collagen Denaturation Status of Cortical Bone by Raman Spectroscopy [PhD thesis]. Cleveland, OH: Case Western Reserve University; January 2017.
2013	Burket JC. Alterations in Tissue Composition and Nanomechanical Properties With Ageing, Osteoporosis, and Treatment [PhD thesis]. Ithaca, NY: Cornell University; January 2013.
2020	Lekkala S. Characterization of Material and Compositional Properties of Iliac Bone from Postmenopausal Women With Worsening Glycemic Control [Master's thesis]. Ithaca, NY: Cornell University; August 2020.
2021	Sacher S. Characterization of Trabecular Morphology, Microdamage Accumulation, and Collagen Crosslinking in Bone Tissue from Individuals With Type II Diabetes Mellitus [Master's thesis]. Ithaca, NY: Cornell University; May 2021.
2007	Schneider P. Ultrastructural Phenotyping of Murine Bone Using Synchrotron Micro- and Nano-Computed Tomography [PhD thesis]. Swiss Federal Institute of Technology Zürich; 2007.
2012	Hamed E. Multiscale Modeling of Elastic Moduli and Strength of Bone [PhD thesis]. University of Illinois at Urbana-Champaign; 2012.
2015	Newman CL. Assessing and Modifying Bone Quality in Chronic Kidney Disease [PhD thesis]. Indianapolis, IN: Indiana University; May 2015.
2012	Yuan F. Finite Element Simulation of the Mechanical Properties of Mineralized Biomaterials [PhD thesis]. Evanston, IL: Northwestern University; August 2012.
2005	Espinoza Orias AA. The Relationship Between the Mechanical Anisotropy of Human Cortical Bone Tissue and Its Microstructure [PhD thesis]. University of Notre Dame; April 2005.
2020	O’Sullivan LM. Time-Sequence of Biomechanical Adaption in Trabecular Tissue During Estrogen Deficiency [PhD thesis]. National University of Ireland Galway; March 2020.
2011	Agnew AM. Histomorphometry of the Elderly Rib: A Methodological Approach With Implications for Biomechanics, Function, and Fracture Risk [PhD thesis]. The Ohio State University; 2011.
2012	Jimenez Palomar I. Mechanical Properties of Bone At the Sub-lamellar Level [PhD thesis]. London, England: Queen Mary University of London; September 2012.
2009	Lievers WB. Effects of Geometric and Material Property Changes on the Apparent Elastic Properties of Cancellous Bone [PhD thesis]. Queen's University; April 2009.
2013	Toal VR. The Mechanics of Microdamage and Microfracture in Trabecular Bone [PhD thesis]. Brisbane, Australia: Queensland University of Technology; September 2013.
2004	Mittra ES. Assessment of Trabecular Bone Quality Using Microstructure, Micro-Mechanics and Micro-Finite Element Modeling [PhD thesis]. Stony Brook, NY: Stony Brook University; May 2004.
2009	Ruppel ME. Alterations in the Mineral and Collagen Matrix of Bisphosphonate-Treated Bone and Osteoblasts [PhD thesis]. Stony Brook, NY: Stony Brook University; May 2009.
2012	Hardisty MR. Not Tough Enough: Why Bone Turns Pale When it Feels Stressed [PhD thesis]. Davis, CA: Davis, University of California; 2012.
2020	Amromanoh OA. An Experimental Study of the Effect of Bone Inorganic-Organic Composition on the Mechanical Properties [Master's thesis]. Winnipeg, MB: University of Manitoba; April 2020.
2020	Ahn T. Understanding Nanoscale Hierarchical Nature of Pore and Chemical Heterogeneity in Bone as a Function of Tissue Ages [PhD thesis]. University of Michigan; 2020.
2012	Barkaoui A. Modélisation multiéchelle du comportement mécano-biologique de l’os humain: De l’ultrastructure au remodelage osseux [PhD thesis]. University of Orleans; 2012.
2022	Snow TJ. An Investigation of the Role of Collagen Network on the Dynamic Fracture Initiation Toughness of Bovine Cortical Bone [Master's thesis]. University of Utah; December 2022.
2013	Islam MM. Effect of Coring Conditions on Temperature Rise in Bone [Master's thesis]. San Antionio, TX: University of Texas at San Antonio; August 2013.

Year	Entry
2002	Currey JD. Bones: Structure and Mechanics. Princeton, NJ: Princeton University Press; 2002.
2001	Vashishth D, Gibson GJ, Khoury JI, Schaffler MB, Kimura J, Fyhrie DP. Influence of nonenzymatic glycation on biomechanical properties of cortical bone. Bone. February 2001;28(2):195-201.
2002	Wang X, Shen X, Li X, Agrawal CM. Age-related changes in the collagen network and toughness of bone [published correction appears in Bone. 2003;32(1):107]. Bone. 2002;31(1):1-7.
1996	Jepsen KJ, Goldstein SA, Kuhn JL, Schaffler MB, Bonadio J. Type‐I collagen mutation compromises the post‐yield behavior of Mov13 long bone. J Orthop Res. May 1996;14(3):493-499.
1997	Misof K, Landis WJ, Klaushofer K, Fratzl P. Collagen from the osteogenesis imperfecta mouse model (oim) shows reduced resistance against tensile stress. J Clin Invest. July 1997;100(1):40-45.
1996	McKee MD, Nanci A. Osteopontin at mineralized tissue interfaces in bone, teeth, and osseointegrated implants: ultrastructural distribution and implications for mineralized tissue formation, turnover, and repair. Microsc Res Tech. February 1996;33(2):141-164.
1988	Rice JC, Cowin SC, Bowman JA. On the dependence of the elasticity and strength of cancellous bone on apparent density. J Biomech. 1988;21(2):155-168.
1999	Jepsen KJ, Davy DT, Krzypow DJ. The role of the lamellar interface during torsional yielding of human cortical bone. J Biomech. March 1999;32(3):303-310.
1997	Currey JD, Foreman J, Laketić I, Mitchell J, Pegg DE, Reilly GC. Effects of ionizing radiation on the mechanical properties of human bone. J Orthop Res. January 1997;15(1):111-117.
2002	Sarkar S, Mitlak BH, Wong M, Stock JL, Black DM, Harper KD. Relationships between bone mineral density and incident vertebral fracture risk with raloxifene therapy. J Bone Miner Res. January 2002;17(1):1-10.
1996	Paul RG, Bailey AJ. Glycation of collagen: the basis of its central role in the late complications of ageing and diabetes. Int J Biochem Cell Biol. December 1996;28(12):1297-1310.
2002	Benezra Rosen V, Hobbs LW, Spector M. The ultrastructure of anorganic bovine bone and selected synthetic hyroxyapatites used as bone graft substitute materials. Biomaterials. February 2002;23(3):921-928.
2002	Corsi A, Xu T, Chen X-D, Boyde A, Liang J, Mankani M, Sommer B, Iozzo RV, Eichstetter I, Gehron Robey P, Bianco P, Young MF. Phenotypic effects of biglycan deficiency are linked to collagen fibril abnormalities, are synergized by decorin deficiency, and mimic ehlers-danlos-like changes in bone and other connective tissues. J Bone Miner Res. July 2002;17(7):1180-1189.
1999	Hamer AJ, Stockley I, Elson RA. Changes in allograft bone irradiated atdifferent temperatures. J Bone Joint Surg. March 1999;81B(2):342-344.
2000	Liu D, Wagner HD, Weiner S. Bending and fracture of compact circumferential and osteonal lamellar bone of the baboon tibia. J Mater Sci Mater Med. January 2000;11(1):49-60.
2002	Homminga J, McCreadie BR, Ciarelli TE, Weinans H, Goldstein SA, Huiskes R. Cancellous bone mechanical properties from normals and patients with hip fractures differ on the structure level, not on the bone hard tissue level. Bone. May 2002;30(5):759-764.
1999	Bailey AJ, Sims TJ, Ebbesen EN, Mansell JP, Thomsen JS, Mosekilde L. Age-related changes in the biochemical properties of human cancellous bone collagen: relationship to bone strength. Calcif Tiss Int. September 1999;65(3):203-210.
1999	Zioupos P, Currey JD, Hamer AJ. The role of collagen in the declining mechanical properties of aging human cortical bone. J Biomed Mater Res. May 1999;A45(2):108-116.
2002	Burr DB. The contribution of the organic matrix to bone's material properties. Bone. July 2002;31(1):8-11.
1998	Knott L, Bailey AJ. Collagen cross-links in mineralizing tissues: a review of their chemistry, function, and clinical relevance. Bone. March 1998;22(3):181-187.
1999	Currey JD. What determines the bending strength of compact bone? J Exp Biol. September 1999;202(18):2495-2503.
2001	Grabner B, Landis WJ, Roschger P, Rinnerthaler S, Peterlik H, Klaushofer K, Fratzl P. Age- and genotype-dependence of bone material properties in the osteogenesis imperfecta murine model (oim). Bone. November 2001;29(5):453-457.
2002	Hellmich C, Ulm F-J. Are mineralized tissues open crystal foams reinforced by crosslinked collagen? some energy arguments. J Biomech. September 2002;35(9):1199-1212.