The morphology of the calcification front in articular cartilage:​ its significance in joint function

Bullough, Peter G.; Jagannath, Anand

Affiliations

¹Department of Orthopaedic Pathology at the Hospital for Special Surgery, affiliated with the New York Hospital and the Cornell University Medical College, 535 East 70th Street, New York, New York 10021, USA

Abstract

Biochemical and histochemical studies have indicated that there is specific cellular activity in the region of the calcification front of articular cartilage implying that a regulation process takes place there. Using scanning and transmission electron microscopy and light microscopy to examine tissue sections of both undecalcified and decalcified articular cartilage in the region of the calcification front, we have looked at its morphology with particular reference to its cellular control. Our observations show that physiological calcification is an active process under cellular control and is related to the presence of extracellular membrane-bound matrix vesicles

Links

DOI: 10.1302/0301-620X.65B1.6337169

PubMed: 6337169

WoS: A1983QA02900018

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Cited By (31)

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